Neutropenic enterocolitis. Clinical diagnosis and treatment.

abstract：:Multifocal osteosarcoma with unique patho-biological features in a 23-year old white male is reported. The natural history and classification of multiple osteosarcomas are reviewed. A proposal is presented for evaluation of the multicentric origin in future cases. ...

journal_title：Cancer

authors： Mahoney JP,Spanier SS,Morris JL

更新日期：1979-11-01 00:00:00

abstract：:Nutrients as therapy for patients with cancer are important as adjunctive therapy, i.e., adequate nutrition may be important for the success of whatever form of therapy is administered. Diets deficient in certain amino acids have some selectivity when tested against experimental tumors propagated in vivo. Such diets h...

journal_title：Cancer

authors： Bertino JR

更新日期：1979-05-01 00:00:00

abstract：BACKGROUND:The Akt/mammalian target of the rapamycin (mTOR) signaling pathway represents a promising target for cancer therapy. The phosphorylation status of Akt and of mTOR's phosphorylation target eukaryotic initiation factor 4E-binding protein 1 (4E-BP1) is often used to assess the activity of Akt and mTOR signaling...

journal_title：Cancer

authors： Akcakanat A,Sahin A,Shaye AN,Velasco MA,Meric-Bernstam F

更新日期：2008-06-01 00:00:00

abstract：:Lobular carcinoma in situ (LCIS) has uncertain malignant potential; biologic markers that will identify patients at risk for a poor clinical outcome have been sought actively. Amplification of the c-erbB-2 protooncogene has been correlated with poor prognosis in invasive mammary carcinoma, and immunohistochemical eval...

journal_title：Cancer

authors： Porter PL,Garcia R,Moe R,Corwin DJ,Gown AM

更新日期：1991-07-15 00:00:00

abstract：BACKGROUND:The authors sought to determine whether differences existed in patterns of outcome and morbidity between the 3 thigh compartments after limb-sparing surgery and postoperative radiation therapy (RT). METHODS:A total of 255 patients with primary soft tissue sarcoma (STS) of the thigh were identified in our sa...

journal_title：Cancer

authors： Rimner A,Brennan MF,Zhang Z,Singer S,Alektiar KM

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:The purpose of the current study was to describe a population of young patients with breast carcinoma, their characteristics at the time of diagnosis, and the association of these characteristics with disease recurrence and survival. METHODS:Four hundred fifty-two women age < or = 35 years with breast carci...

journal_title：Cancer

authors： Gonzalez-Angulo AM,Broglio K,Kau SW,Eralp Y,Erlichman J,Valero V,Theriault R,Booser D,Buzdar AU,Hortobagyi GN,Arun B

更新日期：2005-06-15 00:00:00

abstract：:Systemic aspergillosis is encountered with increasing prevalence in immunocompromised patients undergoing chemotherapy. The current communication describes the clinical and postmortem findings in three leukemic patients who developed myocardial infarction secondary to Aspergillus embolization of the coronary arteries....

journal_title：Cancer

authors： Andersson BS,Luna MA,McCredie KB

更新日期：1986-11-01 00:00:00

abstract：BACKGROUND:Upfront autologous hematopoietic stem cell transplantation (AHCT) remains an important therapy in the management of patients with multiple myeloma (MM), a disease of older adults. METHODS:The authors investigated the outcomes of AHCT in patients with MM who were aged ≥70 years. The Center for International ...

journal_title：Cancer

authors： Munshi PN,Vesole D,Jurczyszyn A,Zaucha JM,St Martin A,Davila O,Agrawal V,Badawy SM,Battiwalla M,Chhabra S,Copelan E,Kharfan-Dabaja MA,Farhadfar N,Ganguly S,Hashmi S,Krem MM,Lazarus HM,Malek E,Meehan K,Murthy HS,Ni

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:Results from numerous trials have indicated that breast-conserving therapy (BCT) produces outcomes equivalent to those produced by mastectomy in terms of both locoregional control and survival. However, conservative treatment has resulted in the dilemma of how best to address recurrences when they appear in ...

journal_title：Cancer

authors： Vicini FA,Antonucci JV,Goldstein N,Wallace M,Kestin L,Krauss D,Kunzmann J,Gilbert S,Schell S

更新日期：2007-04-01 00:00:00

abstract：BACKGROUND:The prognostic impact of DNA mismatch repair (MMR) status remains controversial in patients with stage III colon cancer who are treated with adjuvant chemotherapy (AC). The aim of this study was to evaluate the survival outcome of AC in deficient mismatch repair (dMMR)/microsatellite instable (MSI) stage III...

journal_title：Cancer

authors： Shaib WL,Zakka KM,Jiang R,Yan M,Alese OB,Akce M,Wu C,Behera M,El-Rayes BF

更新日期：2020-09-15 00:00:00

abstract：:Eighty-seven previously untreated patients with pathologic Stage IA, II (A or B), or IIIA Hodgkin's disease were randomized over a 48-month period to receive either megavoltage extended field radiotherapy alone or megavoltage radiotherapy limited to involved lymph node sites (including at least an upper mantle field) ...

journal_title：Cancer

authors： O'Connell MJ,Wiernik PH,Brace KC,Byhardt RW,Greene WH

更新日期：1975-04-01 00:00:00

abstract：:In a former series of 60 resected Stage II nonseminomatous germinal testis tumors the authors succeeded in demonstrating that adjuvant cisplatin, vinblastine, and bleomycin (PVB) was able to significantly improve survival (100% in 11 treated versus 28.5% in 7 historical controls, P less than 0.01) only in patients wit...

journal_title：Cancer

authors： Pizzocaro G,Zanoni F,Milani A,Piva L,Salvioni R,Pasi M,Pilotti S,Monfardini S

更新日期：1984-03-15 00:00:00

abstract：BACKGROUND:Sunitinib malate is an orally bioavailable tyrosine kinase inhibitor that is active against many tyrosine kinase receptors involving crucial pathways in both healthy tissues and malignant tissues. Because its use in clinical practice is quite recent, many of its possible side effects remain unknown. In this ...

journal_title：Cancer

authors： Baldazzi V,Tassi R,Lapini A,Lunghi A,Garofoli E,Caruso S,Carini M,Mazzanti R

更新日期：2012-06-15 00:00:00

abstract：BACKGROUND:Gastrointestinal stromal tumors (GISTs) are a specific clinicopathologic entity characterized by activating mutations in the c-KIT gene. These mutations are associated with increased immunohistochemical staining for the c-KIT protein. Because many GISTs display a definitive response to the KIT inhibitor imat...

journal_title：Cancer

authors： Willmore-Payne C,Layfield LJ,Holden JA

更新日期：2005-06-25 00:00:00

abstract：:Because Langerhans' cells (LC) (CD1a-positive epidermal cells) have been discussed to be involved in the pathogenesis of mycosis fungoides and Sézary syndrome, the authors examined the influence of densities of Langerhans' cells and, concurrently, of other phenotypes retrospectively on survival of 35 patients. Cell de...

journal_title：Cancer

authors： Meissner K,Michaelis K,Rehpenning W,Löning T

更新日期：1990-05-01 00:00:00

abstract：BACKGROUND:A series of retrospective studies have reported that patients with human epidermal growth factor receptor 2(HER2)-positive breast cancer are at a greater risk of central nervous system (CNS) metastases. Trastuzumab, which does not cross the blood-brain barrier, has been associated with this increased risk. ...

journal_title：Cancer

authors： Musolino A,Ciccolallo L,Panebianco M,Fontana E,Zanoni D,Bozzetti C,Michiara M,Silini EM,Ardizzoni A

更新日期：2011-05-01 00:00:00

abstract：:In 186 women with breast cancer, there was a progressive increase in the proportion of axillary nodal involvement as the number of pregnancies increased from zero to two or more (P = 0.026). Logistic regression analysis demonstrated that this effect was independent of the known relationship of age and tumor size to no...

journal_title：Cancer

authors： Lehrer S,Levine E,Savoretti P,Cropley J,Botstein C,Song HK,Mandell L,Shank B

更新日期：1992-02-15 00:00:00

abstract：:Estradiol and testosterone levels in the peripheral and ovarian circulation of patients with endometrial cancer and of postmenopausal women were studied. These levels proved to be the same in the two groups. The ovaries of neither group secreted estradiol. The testosterone level in the ovarian circulation of all exami...

journal_title：Cancer

authors： Schenker JG,Weinstein D,Okon E

更新日期：1979-11-01 00:00:00

abstract：:In search of tumor-associated components in human melanomas and gliomas, plasma membranes were isolated from these tumors and compared morphologically, biochemically and immunologically with those from normal human brain. The preparations exhibited a comparable ultrastructure of empty vesicles of various form and size...

journal_title：Cancer

authors： Birkmayer GD

更新日期：1981-12-01 00:00:00

abstract：BACKGROUND:It has been shown that adoptive immunotherapy with Epstein-Barr virus (EBV)-specific cytotoxic T-lymphocytes (CTL) is effective for the treatment of EBV-induced lymphoproliferative disease in stem cell transplantation recipients and organ transplantation recipients. The role of EBV CTL in other tumors for wh...

journal_title：Cancer

authors： Lucas KG,Salzman D,Garcia A,Sun Q

更新日期：2004-05-01 00:00:00

abstract：:One hundred twenty-seven white European patients with differentiated thyroid cancer were typed for human lymphocyte antigen (HLA) DR specificities. There was no significant deviation from the HLA-DR distribution observed in 160 normal patient controls, neither in the entire group nor in the patient groups with nonmedu...

journal_title：Cancer

authors： Weissel M,Kainz H,Hoefer R,Mayr WR

更新日期：1988-12-15 00:00:00

abstract：:Serum sialyltransferases and fucosyltransferases measured by an affinity adsorbent technique were studied in 27 exactly defined patients with malignant pulmonary diseases. Fourteen patients with benign pulmonary diseases and 56 with benign surgical diseases were used as controls. Enzyme activities were expressed as am...

journal_title：Cancer

authors： Ronquist G,Nou E

更新日期：1983-11-01 00:00:00

abstract：BACKGROUND:Retroperitoneal lymph node dissection is a fundamental step in the surgical management of patients with pelvic gynecologic malignancies, but its applicability to geriatric patients is controversial. The objective of this study was to evaluate whether pelvic and aortic lymphadenectomy in elderly patients with...

journal_title：Cancer

authors： Giannice R,Susini T,Ferrandina G,Poerio A,Margariti PA,Carminati R,Marana E,Mancuso S,Scambia G

更新日期：2001-11-15 00:00:00

abstract：BACKGROUND:There is concern that antioxidant supplement use during chemotherapy and radiation therapy may decrease treatment effects, yet the effects of such supplements on recurrence and survival are largely unknown. METHODS:The authors prospectively examined the associations between antioxidant use after breast canc...

journal_title：Cancer

authors： Greenlee H,Kwan ML,Kushi LH,Song J,Castillo A,Weltzien E,Quesenberry CP Jr,Caan BJ

更新日期：2012-04-15 00:00:00

abstract：:Five patients with angiosarcoma of the breast were treated with surgery, radiotherapy and an adjuvant Adriamycin containing regimen. Two patients remain disease-free at 38+ and 20+ months. The median survival of previously reported cases is 22 months with only five patients disease-free at five years. Possible hormona...

journal_title：Cancer

authors： Antman KH,Corson J,Greenberger J,Wilson R

更新日期：1982-11-15 00:00:00

abstract：BACKGROUND:To retrospectively evaluate the significance of morphologic examination and ancillary studies performed on bilateral bone marrow biopsy specimens, 1864 bone marrow samples were studied. METHODS:Bilateral bone marrow biopsy specimens included 883 specimens that were evaluated for involvement by non-Hodgkin l...

journal_title：Cancer

authors： Wang J,Weiss LM,Chang KL,Slovak ML,Gaal K,Forman SJ,Arber DA

更新日期：2002-03-01 00:00:00

abstract：BACKGROUND:Partial splenic embolization (PSE) has been used to improve hematologic parameters related to hypersplenism. The purpose of this study was to review our institutional experience with PSE for cancer patients with thrombocytopenia because of splenic sequestration precluding the administration of systemic thera...

journal_title：Cancer

authors： Kauffman CR,Mahvash A,Kopetz S,Wolff RA,Ensor J,Wallace MJ

更新日期：2008-05-15 00:00:00

abstract：BACKGROUND:Flow cytometric analysis of trophoblastic tissue has shown that most partial hydatidiform moles (PMs) are triploid, whereas most complete moles (CMs) are diploid or tetraploid. Ploidy analysis can support a diagnosis of CM or PM. However, in some cases, a precise diagnosis cannot be rendered. METHODS:This s...

journal_title：Cancer

authors： Bocklage TJ,Smith HO,Bartow SA

更新日期：1994-06-01 00:00:00

abstract：:Three bleomycin-resistant (BLMr) human carcinoma cell lines (HeLa-BLMr, KB-BLMr, and Hepd-uvBLMr) were established in culture by progressively increasing the concentration of bleomycin (BLM). HeLa-BLMr and KB-BLMr were obtained after 5 and 2 months of incubation with BLM, whereas the establishment of Hepd-uvBLMr requi...

journal_title：Cancer

authors： Urade M,Sugi M,Miyazaki T

更新日期：1988-04-15 00:00:00

abstract：BACKGROUND:Microsatellite instability (MIN) appears to be a novel molecular mechanism in carcinogenesis and is believed to reflect multiple replication errors. The authors analyzed MIN in de novo acute leukemia and its association with expression of the human MSH3 (hMSH3) gene and point mutations of the N-ras gene. The...

journal_title：Cancer

authors： Tanosaki S,Inokuchi K,Shimada T,Dan K

更新日期：1998-08-01 00:00:00