Epidermal Langerhans' cell densities influence survival in mycosis fungoides and Sézary syndrome.

abstract：:A 44-year-old patient with histologically proven bilateral ulcerated lymph node metastases from a carcinoma of the penis was treated by sequenced combined chemotherapy and radical irradiation. Methotrexate and bleomycin were administered at weekly intervals for 5 weeks, followed by radiation with a split-course coning...

journal_title：Cancer

authors： Abratt RP

更新日期：1984-10-15 00:00:00

abstract：BACKGROUND:Second primary tumors are a leading cause of death among patients with head and neck cancer; therefore, early detection of these tumors is necessary. In the current study, the authors aimed to evaluate the diagnostic capacity of (18)F-fluorodeoxyglucose dual-head positron emission tomography (FDG-PET) for de...

journal_title：Cancer

authors： Stokkel MP,Moons KG,ten Broek FW,van Rijk PP,Hordijk GJ

更新日期：1999-12-01 00:00:00

abstract：BACKGROUND:Active surveillance (AS) is an accepted means of managing low-risk prostate cancer. Because of the rarity of downstream events, data from existing AS cohorts cannot yet address how differences in surveillance intensity affect metastasis and mortality. This study projected the comparative benefits of differen...

journal_title：Cancer

authors： Lange JM,Laviana AA,Penson DF,Lin DW,Bill-Axelson A,Carlsson SV,Newcomb LF,Trock BJ,Carter HB,Carroll PR,Cooperberg MR,Cowan JE,Klotz LH,Etzioni RB

更新日期：2020-02-01 00:00:00

abstract：BACKGROUND:Microphthalmia transcription factor (MITF)-associated (MiT) tumors are a family of rare malignancies, including alveolar soft part sarcoma (ASPS), clear cell sarcoma (CCS), and translocation-associated renal cell carcinoma (tRCC) that have dysregulated expression of oncogenic MITF family proteins. The MET re...

journal_title：Cancer

authors： Wagner AJ,Goldberg JM,Dubois SG,Choy E,Rosen L,Pappo A,Geller J,Judson I,Hogg D,Senzer N,Davis IJ,Chai F,Waghorne C,Schwartz B,Demetri GD

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:Hepatocellular carcinoma (HCC) complicating cirrhosis has a high intrahepatic recurrence rate after treatment by surgical resection or percutaneous ethanol injection (PEI). In this study, certain clinical, biochemical, and pathologic parameters were evaluated as risk factors for intrahepatic tumor recurrence...

journal_title：Cancer

authors： Pompili M,Rapaccini GL,de Luca F,Caturelli E,Astone A,Siena DA,Villani MR,Grattagliano A,Cedrone A,Gasbarrini G

更新日期：1997-04-15 00:00:00

abstract：:A retrospective study was done of all patients who were seen for definitive treatment of adenocarcinoma of the pancreas at the Massachusetts General Hospital from 1963 to 1973. There were a total of 145 patients. Thirty-one patients were treated with radical surgery, with a 16% operative mortality, a 5-year crude surv...

journal_title：Cancer

authors： Tepper J,Nardi G,Sutt H

更新日期：1976-03-01 00:00:00

abstract：:With increasing numbers of survivors from cancer at a young age, the issue of fertility preservation has assumed greater importance. This review describes normal ovarian and testicular function and summarizes what is known about the effect of chemotherapy and radiotherapy on the gonads and uterus. All young patients w...

journal_title：Cancer

authors： Wallace WH

更新日期：2011-05-15 00:00:00

abstract：:The expression of the Thomsen-Friedenreich antigen (T-antigen) in normal and neoplastic urothelium was investigated using paraffin-processed and fresh frozen tissue sections obtained by biopsy from 56 patients. The T-antigen was detected through its binding to the peanut agglutinin (PNA) with two methods: a biotin-avi...

journal_title：Cancer

authors： Limas C,Lange P

更新日期：1986-09-15 00:00:00

abstract：BACKGROUND:There is global variation in the onset of hepatocellular carcinoma (HCC). The objective of the current study was to investigate the impact of country of birth on age at the time of HCC diagnosis in the United States. METHODS:Incident HCC cases diagnosed between 2000 and 2012 in the Surveillance, Epidemiolog...

journal_title：Cancer

authors： Yang JD,Altekruse SF,Nguyen MH,Gores GJ,Roberts LR

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:The authors purpose in this study was to clarify the difference in terms of clinicopathologic features between gastric cancer (GC) with high numbers of DNA methylated genes and CpG island methylator phenotype (CIMP)-positive GC as originally defined. METHODS:We analyzed DNA methylation of 12 tumor-related g...

journal_title：Cancer

authors： Oue N,Mitani Y,Motoshita J,Matsumura S,Yoshida K,Kuniyasu H,Nakayama H,Yasui W

更新日期：2006-03-15 00:00:00

abstract：BACKGROUND:The identification of brain metastases in patients with malignant disease has important implications for determining their treatment and prognosis. Asymptomatic metastatic brain tumors may be detected by surveillance imaging techniques, but longitudinal follow-up of patients who are at risk is sporadic prima...

journal_title：Cancer

authors： Vogelbaum MA,Masaryk T,Mazzone P,Mekhail T,Fazio V,McCartney S,Marchi N,Kanner A,Janigro D

更新日期：2005-08-15 00:00:00

abstract：BACKGROUND AND METHODS:Specimens obtained from 192 patients with Stage III squamous cell carcinoma of the cervix treated by radiation therapy alone were investigated with an immunohistochemical method for the expression of p53CM1, a monoclonal antibody that recognizes wild and mutant type p53 gene products in histologi...

journal_title：Cancer

authors： Oka K,Nakano T,Arai T

更新日期：1993-07-01 00:00:00

abstract：BACKGROUND:Unresolved epidemiologic issues in large bowel cancer include reasons for changes in incidence rates, differences in epidemiology of cancer in the distal and proximal colon and rectal cancer, and the optimal fat and fiber levels for low rates. METHODS:The authors examined questions of suitable procedures fo...

journal_title：Cancer

authors： Wynder EL,Reddy BS,Weisburger JH

更新日期：1992-09-01 00:00:00

abstract：BACKGROUND:Previous reports suggesting a correlation between lymphoproliferative disease and serum levels of beta-2-microglobulin (beta-2M) and in vitro data indicating a role of cytokines in the production of beta-2M prompted a study of serum and urine beta-2M concentration in patients with hemophagocytic syndrome (HP...

journal_title：Cancer

authors： Hibi S,Ikushima S,Fujiwara F,Hashida T,Tsunamoto K,Todo S,Imashuku S

更新日期：1995-04-01 00:00:00

abstract：:Actual HL-A typing has been performed on 115 members of cancer family N, a large kindred (over 1000 members ascertained) showing the findings consistent with the cancer family syndrome. In the cancer-prone line (branches C and D) of the family, 20 of 21 members with cancer had one HL-A haplotype, HL-A2-HL-A12 (relativ...

journal_title：Cancer

authors： Lynch HT,Thomas RJ,Terasaki PI,Ting A,Guirgis HA,Kaplan AR,Magee H,Lynch J,Kraft C,Chaperon E

更新日期：1975-10-01 00:00:00

abstract：BACKGROUND:The importance of the bone marrow microenvironment in multiple myeloma is receiving increasing attention. Recent studies have suggested the importance of cytokine production and cell-cell contact by bone marrow stromal cells in the survival of myeloma cells. METHODS:In the current study, the authors examine...

journal_title：Cancer

authors： Wallace SR,Oken MM,Lunetta KL,Panoskaltsis-Mortari A,Masellis AM

更新日期：2001-04-01 00:00:00

abstract：:Kaposi's sarcoma of the gingiva and skin developed in an HIV-negative renal transplant patient while he was receiving cyclosporine therapy. The Kaposi's sarcoma developed shortly after the patient had an acute infection with cytomegalovirus (CMV). Electron microscopy of the tumor's established cell line showed two typ...

journal_title：Cancer

authors： Siegal B,Levinton-Kriss S,Schiffer A,Sayar J,Engelberg I,Vonsover A,Ramon Y,Rubinstein E

更新日期：1990-02-01 00:00:00

abstract：:A retrospective analysis of 12 patients with primary central nervous system non-Hodgkin's lymphoma seen from 1958 to 1980 was carried out with emphasis on diagnostic evaluation and treatment results. Computerized tomography (CT) scans were found to be the most valuable diagnostic tool both for initial evaluation as we...

journal_title：Cancer

authors： Mendenhall NP,Thar TL,Agee OF,Harty-Golder B,Ballinger WE Jr,Million RR

更新日期：1983-12-01 00:00:00

abstract：BACKGROUND:Little is known about the natural growth characteristics of untreated glioblastoma before surgical or therapeutic intervention, because patients are rapidly treated after preliminary radiographic diagnosis. Understanding the growth characteristics of uninhibited human glioblastoma may be useful for character...

journal_title：Cancer

authors： Ellingson BM,Nguyen HN,Lai A,Nechifor RE,Zaw O,Pope WB,Yong WH,Nghiemphu PL,Liau LM,Cloughesy TF

更新日期：2016-06-01 00:00:00

abstract：BACKGROUND:In patients with locoregional carcinoma of the esophagus or esophagogastric junction who underwent preoperative chemoradiation, it is unclear whether survival was better predicted by pretherapy clinical stage or by posttherapy pathologic stage. METHODS:The authors studied 235 consecutive patients with preth...

journal_title：Cancer

authors： Chirieac LR,Swisher SG,Ajani JA,Komaki RR,Correa AM,Morris JS,Roth JA,Rashid A,Hamilton SR,Wu TT

更新日期：2005-04-01 00:00:00

abstract：:The acquisition of ligand-independent ESR1 mutations during aromatase inhibitor therapy in metastatic estrogen receptor (ER)-positive breast cancer is a common mechanism of hormonal therapy resistance. Preclinical and clinical studies have demonstrated that ESR1 mutations can preexist in primary tumors and can be enri...

journal_title：Cancer

authors： Dustin D,Gu G,Fuqua SAW

更新日期：2019-11-01 00:00:00

abstract：:Nine patients from 34 to 74 years of age (median, 67 years of age) with uterine papillary serous carcinoma (UPSC) were treated with whole-abdominal radiation therapy (WART) on an adjuvant basis after cytoreductive surgery. All patients were treated with megavoltage photons to an abdominopelvic field to a median dose o...

journal_title：Cancer

authors： Frank AH,Tseng PC,Haffty BG,Papadopoulos DP,Kacinski BM,Dowling SW,Carcangiu ML,Kohorn EI,Chambers JT,Chambers SK

更新日期：1991-10-01 00:00:00

abstract：:Transgenic model systems provide tools for obtaining information that clarifies important relationships between genetic alterations and carcinogenesis. One such relationship is the induction of specific growth factor activities by dominantly acting oncogenes. Using a "transgenic organ" model referred to as mouse prost...

journal_title：Cancer

authors： Thompson TC,Truong LD,Timme TL,Kadmon D,McCune BK,Flanders KC,Scardino PT,Park SH

更新日期：1993-02-01 00:00:00

abstract：:A 30-year-old man underwent orchiectomy in 1962 for a testicular carcinoma composed of choriocarcinomatous and teratocarcinomatous elements. Bilateral pulmonary metastases regressed completely on combination chemotherapy. However, a cerebral metastasis developed in 1963 and caused severe neurologic signs. At craniotom...

journal_title：Cancer

authors： Stolinsky DC

更新日期：1981-03-01 00:00:00

abstract：:In the treatment of gynecologic malignancies, various combinations of surgery, drugs, and radiation therapy are used with increasing frequency. An examination is made of data dealing with combined modalities in the treatment of tumors of the cervix, endometrium, and ovary. Although the efficacy of such treatments has ...

journal_title：Cancer

authors： Brady LW

更新日期：1975-01-01 00:00:00

abstract：BACKGROUND:Allelic deletions are frequent genetic alterations in patients with hepatocellular carcinoma (HCC). METHODS:To evaluate the allelic losses on chromosome 8p in HCC patients and define their clinicopathologic significance, we performed high-density allelotyping on 8p in 60 patients with HCC and analyzed the c...

journal_title：Cancer

authors： Chan KL,Lee JM,Guan XY,Fan ST,Ng IO

更新日期：2002-06-15 00:00:00

abstract：:Three hundred fifteen radioisotopic bone scans ranging from initial scan only to nine scans per patient, performed on 114 patients with adenocarcinoma of the prostate between 1979 and 1984, were reviewed. Seventeen patients had positive scans, ten on initial scan and seven at follow-up. Nine patients had bone pain at ...

journal_title：Cancer

authors： Corrie D,Timmons JH,Bauman JM,Thompson IM

更新日期：1988-06-15 00:00:00

abstract：:Quality assurance for the management of multicenter clinical trials requires timely patient and data accrual and consistency with design parameters. Data from central pathology review, treatment modality, and follow-up as well as trial end points direct the selection of appropriate compliance measures. To integrate th...

journal_title：Cancer

authors： Pollock BH

更新日期：1994-11-01 00:00:00

abstract：BACKGROUND:To identify the factors that contribute to poorer colon carcinoma survival rates for African Americans compared with Caucasians, the authors evaluated survival differences based on the histologic grade (differentiation) of the tumor. METHODS:All 169 African Americans and 229 randomly selected non-Hispanic C...

journal_title：Cancer

authors： Alexander D,Jhala N,Chatla C,Steinhauer J,Funkhouser E,Coffey CS,Grizzle WE,Manne U

更新日期：2005-05-15 00:00:00

abstract：BACKGROUND:African-American (AA) women have lower survival rates from cervical cancer compared with white women. The objective of this study was to examine the influence of socioeconomic status (SES) and other variables on racial disparities in overall survival among women with invasive cervical cancer. METHODS:One th...

journal_title：Cancer

authors： Movva S,Noone AM,Banerjee M,Patel DA,Schwartz K,Yee CL,Simon MS

更新日期：2008-03-15 00:00:00