Tivantinib (ARQ 197), a selective inhibitor of MET, in patients with microphthalmia transcription factor-associated tumors: results of a multicenter phase 2 trial.

abstract：:Mammary carcinomas have been induced by 3.5 Gy whole-body gamma radiation administered at age 40 to 50 days to virgin female Sprague-Dawley rats. In 142 irradiated controls carcinoma incidence averaged 7.8% in survivors observed less than 300 days and 38.3% of those surviving longer (P less than 0.001 by t test). Mamm...

journal_title：Cancer

authors： Lemon HM,Kumar PF,Peterson C,Rodriguez-Sierra JF,Abbo KM

更新日期：1989-05-01 00:00:00

abstract：:Deguelin is a rotenoid compound that exists in abundant quantities in the bark, roots, and leaves of the Leguminosae family of plants. An analysis of evidence from both in vitro and in vivo studies suggests that deguelin displays potent anticancer activity against multiple cancer types and exhibits chemopreventive pot...

journal_title：Cancer

authors： Varughese RS,Lam WS,Marican AABH,Viganeshwari SH,Bhave AS,Syn NL,Wang J,Wong AL,Kumar AP,Lobie PE,Lee SC,Sethi G,Goh BC,Wang L

更新日期：2019-06-01 00:00:00

abstract：:Compliance in oncology clinic attendance was prospectively evaluated over a 12-month period at Harlem Hospital Center, an inner city municipal facility serving a predominantly black population. One hundred patients were followed (97 blacks, 2 Hispanics, 1 white) with an average age of 60 years. There were 41 men and 5...

journal_title：Cancer

authors： Garrett TJ,Ashford A,Savage DG

更新日期：1986-08-01 00:00:00

abstract：BACKGROUND:Epidemiologic studies have recently related benzene hexachloride (BHC) to breast carcinoma risk. Experimental studies have also shown that beta-BHC is weakly estrogenic, hence supporting the alleged association. By directly comparing beta-BHC levels in breast adipose tissue from incident breast carcinoma cas...

journal_title：Cancer

authors： Zheng T,Holford TR,Mayne ST,Owens PH,Ward B,Carter D,Dubrow R,Zahm SH,Boyle P,Tessari J

更新日期：1999-05-15 00:00:00

abstract：:The current classification of cutaneous malignant lymphomas (ML) into low-grade and high-grade lymphomas was found to be of limited reproducibility and permitted only a rough prediction about outcome. With this in mind, the relationship between nuclear DNA content and both prognosis and histologic grading according to...

journal_title：Cancer

authors： Vogt T,Stolz W,Braun-Falco O,Kaudewitz P,Eckert F,Abmayr W,Dummer R,Burg G

更新日期：1991-09-01 00:00:00

abstract：:The discovery of genes responsible for inherited forms of colorectal cancer have the potential to improve cancer risk assessment and counseling. Germline mutations (nonsense, frameshift) of APC are associated with familial adenomatous polyposis, an autosomal dominant syndrome, clinically characterized by young onset, ...

journal_title：Cancer

authors： Petersen GM,Brensinger JD,Johnson KA,Giardiello FM

更新日期：1999-12-01 00:00:00

abstract：BACKGROUND:Although it is believed that p53 suppressor gene mutations, compared with mutations in the K-ras oncogene, occur at a later stage of colorectal tumorigenesis, the distribution of these genetic alterations at an early stage remains poorly characterized. METHODS:The authors analyzed the immunoreactivity for p...

journal_title：Cancer

authors： Hosaka S,Aoki Y,Akamatsu T,Nakamura N,Hosaka N,Kiyosawa K

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:Soft tissue sarcomas of the head and neck represent uncommon malignant neoplasms. With the exception of orbital and parameningeal sites, the treatment of sarcomas in the head and neck has not been standardized. The authors used a prospectively collected database of adult soft tissue sarcomas to identify prog...

journal_title：Cancer

authors： Kraus DH,Dubner S,Harrison LB,Strong EW,Hajdu SI,Kher U,Begg C,Brennan MF

更新日期：1994-07-15 00:00:00

abstract：BACKGROUND:Central nervous system (CNS) recurrence is almost invariably fatal in patients with aggressive non-Hodgkin lymphoma (NHL). Although some protocols are intended to prevent CNS disease, the value of CNS prophylaxis in patients with aggressive NHL remains to be determined. METHODS:We retrospectively analyzed a...

journal_title：Cancer

authors： Tomita N,Kodama F,Kanamori H,Motomura S,Ishigatsubo Y

更新日期：2002-08-01 00:00:00

abstract：:Since primary lymphoma of bone (PLB) exhibits morphologic diversity and variability in individual survival, we analyzed the relationship between histopathologic features and biological behavior in 33 patients treated at the Massachusetts General Hospital. Three major histologic subgroups were identified, based on a va...

journal_title：Cancer

authors： Dosoretz DE,Raymond AK,Murphy GF,Doppke KP,Schiller AL,Wang CC,Suit HD

更新日期：1982-09-01 00:00:00

abstract：:International comparisons have provided striking correlations between fat consumption and risk of breast cancer, but these comparisons do not often consider variations in life style. Case-control studies carried out in several countries showed no real association between fat intake and breast cancer. There is some evi...

journal_title：Cancer

authors： Kritchevsky D

更新日期：1990-09-15 00:00:00

abstract：BACKGROUND:The mortality rate associated with fever accompanied by pulmonary infiltrates after chemotherapy for hematologic malignancies remains higher than the corresponding rate associated with febrile neutropenia without pulmonary infiltrates. Nonetheless, few studies have focused on the factors that predict outcome...

journal_title：Cancer

authors： Offidani M,Corvatta L,Malerba L,Marconi M,Bichisecchi E,Cecchini S,Manso E,Principi T,Gasparini S,Leoni P

更新日期：2004-08-01 00:00:00

abstract：:The cases of three patients with primary carcinoid tumor of the testis were reported. The patients were 41, 44, and 83 years of age. At initial examination, all three had testicular masses with or without associated pain, and none had the carcinoid syndrome. The tumors measured 4.3 cm, 3.0 cm, and 6.5 cm in dimension....

journal_title：Cancer

authors： Zavala-Pompa A,Ro JY,el-Naggar A,Ordóñez NG,Amin MB,Pierce PD,Ayala AG

更新日期：1993-09-01 00:00:00

abstract：BACKGROUND:The authors assessed the prognostic significance of abnormal cyclin dependent kinase inhibitor (CDKI) expression in adenocarcinomas of the uterine cervix. METHODS:Population-based, archival material from patients with International Federation of Gynecology and Obstetrics (FIGO) Stage I and II cervical adeno...

journal_title：Cancer

authors： Alfsen GC,Reed W,Sandstad B,Kristensen GB,Abeler VM

更新日期：2003-11-01 00:00:00

abstract：BACKGROUND:There are few reports comparing the clinicopathologic features of sarcomas of the aorta (SA), sarcomas of the inferior vena cava (SIVC), and sarcomas of the pulmonary artery (SPA). METHODS:The authors retrospectively reviewed 11 SA, 16 SIVC, and 16 SPA, and compared clinical, pathologic, and immunohistochem...

journal_title：Cancer

authors： Burke AP,Virmani R

更新日期：1993-03-01 00:00:00

abstract：:A study of primary epithelial neoplasms of the appendix (with the exception of classical carcinoids), produced 24 adenocarcinomas and 42 benign lesions from the files of the Laboratory of Surgical Pathology of Columbia University. Invasive adenoarcinomas were often complicated by appendicitis and were then unexpectedl...

journal_title：Cancer

authors： Wolff M,Ahmed N

更新日期：1976-05-01 00:00:00

abstract：BACKGROUND:Chemotherapy-induced nausea and vomiting remain common, distressing side effects of chemotherapy. It has been reported that acupressure prevents chemotherapy-induced nausea in adults, but it has not been well studied in children. METHODS:In this multicenter, prospective, randomized, single-blind, sham-contr...

journal_title：Cancer

authors： Dupuis LL,Kelly KM,Krischer JP,Langevin AM,Tamura RN,Xu P,Chen L,Kolb EA,Ullrich NJ,Sahler OJZ,Hendershot E,Stratton A,Sung L,McLean TW

更新日期：2018-03-15 00:00:00

abstract：BACKGROUND:A single-institution, prospective, randomized open trial was performed to compare ondansetron and granisetron in the prevention of chemotherapy-related nausea and vomiting. The effect of antemetic drugs was analyzed indipendently for patients treated with highly emetogenic chemotherapy (Study 1), and those t...

journal_title：Cancer

authors： Gebbia V,Cannata G,Testa A,Curto G,Valenza R,Cipolla C,Latteri MA,Gebbia N

更新日期：1994-10-01 00:00:00

abstract：BACKGROUND:Louisiana is one of the few Southern states that enacted the Medicaid expansion of the Patient Protection and Affordable Care Act (ACA). To the authors' knowledge, the issue of how this has affected the breast cancer landscape in Louisiana is unknown. The authors have postulated that ACA expansion had a posi...

journal_title：Cancer

authors： Chu QD,Li T,Hsieh MC,Yi Y,Gibbs JF,Lyons JM 3rd,Wu XC

更新日期：2020-11-03 00:00:00

abstract：BACKGROUND:Familial breast cancer risk studies usually overlook the dynamic nature of family history. METHODS:The authors assessed the effect of incorporating the timing of cancer diagnosis events into the assessment of familial risks of breast cancer in first-degree and second-degree relatives in a nationwide cohort ...

journal_title：Cancer

authors： Mukama T,Kharazmi E,Sundquist K,Sundquist J,Brenner H,Fallah M

更新日期：2020-06-15 00:00:00

abstract：:Currently attention is focused on the testicle as a site of leukemic relapse. Leukemic involvement of the ovary has been described in several autopsy series with an incidence of 11-50% in patients with bone marrow relapse, but has rarely been reported during the clinical course of leukemia. In this report, four girls ...

journal_title：Cancer

authors： Cecalupo AJ,Frankel LS,Sullivan MP

更新日期：1982-08-01 00:00:00

abstract：BACKGROUND:The diagnostic accuracy of technetium-99m methoxyisobutylisonitrile (Tc-MIBI) single photon emission computed tomography (SPECT) and computed tomography (CT) of the head and neck for differentiating recurrent or residual nasopharyngeal carcinomas (NPC) from benign lesions after radiotherapy was compared with...

journal_title：Cancer

authors： Kao CH,Shiau YC,Shen YY,Yen RF

更新日期：2002-04-01 00:00:00

abstract：:Eighty-six children with non-Hodgkin's lymphoma were studied from 1964 to January 31, 1975. Seventy-six percent of the 43 patients in the nonprotocol group had far advanced disease, and 76% had Rappaport's diffuse histology. Only 11% of these patients survived free of disease. The second group of 43 patients received ...

journal_title：Cancer

authors： Wollner N,Burchenal JH,Lieberman PH,Exelby P,D'Angio G,Murphy ML

更新日期：1976-01-01 00:00:00

abstract：BACKGROUND:Triple-negative breast cancer (TNBC) is defined as breast cancer that is negative for estrogen receptor, progesterone receptor, and human epidermal growth factor receptor 2. TNBC represents 15% of all invasive breast cancers, but some studies have suggested that its prevalence differs between races. To the a...

journal_title：Cancer

authors： Lara-Medina F,Pérez-Sánchez V,Saavedra-Pérez D,Blake-Cerda M,Arce C,Motola-Kuba D,Villarreal-Garza C,González-Angulo AM,Bargalló E,Aguilar JL,Mohar A,Arrieta Ó

更新日期：2011-08-15 00:00:00

abstract：BACKGROUND:Many experienced oncologists have encountered patients with proven non-small cell lung cancer (NCLC) who received modest doses of palliative radiotherapy (RT) and who unexpectedly survived for > 5 years; some were apparently cured. We used a very large prospective database to estimate the frequency of this p...

journal_title：Cancer

authors： Mac Manus MP,Matthews JP,Wada M,Wirth A,Worotniuk V,Ball DL

更新日期：2006-03-01 00:00:00

abstract：:The establishment and characterization of 11 human lung cancer cell lines are described in this article. Nine of these cell lines were established over a 5-year period, from 1983 to 1988, from patients treated at the Kingston Regional Cancer Centre. These include eight definite or probable small cell lung cancer (SCLC...

journal_title：Cancer

authors： Campling BG,Haworth AC,Baker HM,Greer DL,Holden JJ,Bradley EC,Pym J,Dexter DF

更新日期：1992-04-15 00:00:00

abstract：BACKGROUND:Recently, peripheral lung adenocarcinomas (PLA) measuring < or = 3 cm in greatest dimension often have been diagnosed using diagnostic radiology. The objective of the current study was to determine which cytologic factors are associated with a favorable outcome and an unfavorable outcome in patients with PLA...

journal_title：Cancer

authors： Kobayashi Y,Yokose T,Kawamura K,Iwasaki S,Murata Y,Onuma S,Hasebe T,Nagai K,Sasaki S,Ochiai A

更新日期：2005-02-25 00:00:00

abstract：BACKGROUND:The authors compared the survival outcomes of radiotherapy+/-salvage surgery to surgery+/-postoperative radiotherapy for patients with squamous cell cancer of the hypopharynx. There was no evidence beyond observational studies and no consensus on the which treatment is most effective for this patient group. ...

journal_title：Cancer

authors： Hall SF,Groome PA,Irish J,O'Sullivan B

更新日期：2009-12-15 00:00:00

abstract：BACKGROUND:Although flow cytometric DNA analysis has been recognized to be a useful prognostic indicator for patients with squamous cell carcinoma of the esophagus, the biologic significance of DNA aneuploidy remains to be elucidated. METHODS:Twenty-five patients with squamous cell carcinoma of the esophagus who under...

journal_title：Cancer

authors： Watanabe M,Kuwano H,Tanaka S,Toh Y,Sadanaga N,Sugimachi K

更新日期：1999-06-01 00:00:00

abstract：BACKGROUND:Nonionizing radiation, such as radiofrequency field and near infrared laser, induces thermal cytotoxicity in cancer cells treated with gold nanoparticles. Quantum dots are fluorescent semiconducting nanoparticles that were hypothesized to induce similar injury after radiofrequency field irradiation. METHODS...

journal_title：Cancer

authors： Glazer ES,Curley SA

更新日期：2010-07-01 00:00:00