Abstract:
:Eighty-six children with non-Hodgkin's lymphoma were studied from 1964 to January 31, 1975. Seventy-six percent of the 43 patients in the nonprotocol group had far advanced disease, and 76% had Rappaport's diffuse histology. Only 11% of these patients survived free of disease. The second group of 43 patients received the LSA2L2 protocol. Seventy-six percent had advanced disease and 86% diffuse histology. Of these patients 76% are surviving free of disease with a median observation time of 25+ months. Fifty-one percent of the survivors are off therapy and without evidence of disease. Prognostic factors such as primary sites, stages, histology, and others are discussed. The most important prognostic factor is early and aggressive therapy, and the achievement of a complete response status within 1-2 months from onset of therapy.
journal_name
Cancerjournal_title
Cancerauthors
Wollner N,Burchenal JH,Lieberman PH,Exelby P,D'Angio G,Murphy MLdoi
10.1002/1097-0142(197601)37:1<123::aid-cncr2820370subject
Has Abstractpub_date
1976-01-01 00:00:00pages
123-34issue
1eissn
0008-543Xissn
1097-0142journal_volume
37pub_type
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