Tissue factor expression in human colorectal carcinoma: correlation with hepatic metastasis and impact on prognosis.

abstract：:Seventy-eight patients with metastatic cancer to the lungs underwent flexible fiberoptic bronchoscopy for diagnosis. The patients were divided into two groups by presenting radiographic pattern as: (I) diffuse linear interstitial infiltrations (55 patients); and (II) localized or multiple nodular opacities (23 patient...

journal_title：Cancer

authors： Chuang MT,Padilla ML,Teirstein AS

更新日期：1983-11-15 00:00:00

abstract：BACKGROUND:To evaluate the pathologic characteristics of the primary tumor relative to local control, survival, and freedom from distant metastases, an analysis was performed of 172 patients with ductal carcinoma in situ (intraductal carcinoma) of the breast treated with breast-conserving surgery and definitive breast ...

journal_title：Cancer

authors： Solin LJ,Yeh IT,Kurtz J,Fourquet A,Recht A,Kuske R,McCormick B,Cross MA,Schultz DJ,Amalric R

更新日期：1993-04-15 00:00:00

abstract：:During the past decade, one of the major changes in the field of oncology has been in the surgical approach to primary and secondary cancer of the liver. As a result of data and experience gained in liver transplantation programs and with the application of vascular surgical principles, resectability rates have been i...

journal_title：Cancer

authors： Fortner JG,MacLean BJ,Kim DK,Howland WS,Turnbull AD,Goldiner P,Carlon G,Beattie EJ Jr

更新日期：1981-05-01 00:00:00

abstract：:Trabecular carcinoma of the skin (Merkel cell tumor), a neoplasm of putative neural origin, must be differentiated from other small cell tumors primary or metastatic to skin. In order to provide more objective diagnostic criteria, four were examined using monoclonal antibodies against neurofilament proteins (NF) and a...

journal_title：Cancer

authors： Leff EL,Brooks JS,Trojanowski JQ

更新日期：1985-08-01 00:00:00

abstract：:The close observation of patients treated for testicular cancer led to the suspicion of intrathoracic and/or mediastinal metastases on radiologic examination in a number of patients without other evidence of relapse. This report presents two patients with combined seminomatous and nonseminomatous germ cell tumors with...

journal_title：Cancer

authors： Looijen R,Hoekstra HJ,Sleijfer DT,Postmus P,Oosterhuis JW,de Boer WJ,Schraffordt Koops H

更新日期：1990-11-15 00:00:00

abstract：:In estrogen target tissues and hormone-dependent tumors, the steroid enters the cells and binds to a cytoplasmic protein called the estrogen receptor (ER). The steroid-receptor complex then migrates to the nuclei, where it initiates the biochemicial events characteristic of estrogen stimulation. Since ER is absent in ...

journal_title：Cancer

authors： McGuire WL

更新日期：1975-08-01 00:00:00

abstract：:The authors found metastases to the heart in 10.7% of 1029 autopsy cases in which a malignant neoplasm was diagnosed. The lung was the commonest primary site (36.4%) and adenocarcinoma was the most frequent cell type (36.4%) of neoplasms metastatic to heart. Nonepithelial tumors accounted for 22.7% of cardiac metastas...

journal_title：Cancer

authors： Klatt EC,Heitz DR

更新日期：1990-03-15 00:00:00

abstract：:This study delineates the temporal relationship between immune complex formation and tumor growth, and provides one possible explanation for host immunosuppression during tumor growth. The authors have studied serial circulating immune complex (CIC) levels and interleukin (IL) elaboration by peripheral blood cells (IL...

journal_title：Cancer

authors： Ravikumar T,Steele G Jr,Rodrick M,Ross D,Wilson R,Lahey S,Wright D,Munroe A,King V

更新日期：1984-03-15 00:00:00

abstract：BACKGROUND:The objective of this study was to define the effects of socioeconomic status (SES) and other demographic variables on outcomes for patients with pancreatic adenocarcinoma. METHODS:Florida cancer registry and inpatient hospital data were queried for pancreatic adenocarcinoma diagnosed from 1998 to 2002. RE...

journal_title：Cancer

authors： Cheung MC,Yang R,Byrne MM,Solorzano CC,Nakeeb A,Koniaris LG

更新日期：2010-02-01 00:00:00

abstract：:Common myths about nutrition education and care of cancer patients are debunked and realities are discussed. First, frequently held misconceptions of nonspecialized health professionals are considered. These include the myths that diet change in the population will be rapid now that dietary guidelines to prevent cance...

journal_title：Cancer

authors： Dwyer J

更新日期：1986-10-15 00:00:00

abstract：:Thirty-eight patients with metastatic colorecal carcinoma were treated with 5-fluorouracil (5-FU), and 38 patients were treated with the combination of 5-FU, cyclophosphamide, and methotrexate. In terms of percent response, response duration, and survival there was no apparent difference between the two regimens. Comb...

journal_title：Cancer

authors： Richards F 2nd,Pajak TL,Cooper MR,Spurr CL

更新日期：1975-11-01 00:00:00

abstract：:Fifteen cases of pure supradiapragmatic lymphoma with initial prominent antero-superior mediastinal involvement displaying a B-cell pattern of reactivity were studied. These cases occurred in six men and nine women with a median age of 33 years at diagnosis (range, 23 to 75 years). Supradiapragmatic peripheral lymphad...

journal_title：Cancer

authors： Lavabre-Bertrand T,Donadio D,Fegueux N,Jessueld D,Taib J,Charlier D,Rousset T,Emberger JM,Baldet P,Navarro M

更新日期：1992-05-15 00:00:00

abstract：BACKGROUND:The incidence and pattern of brain metastases was analyzed among patients who achieved a pathological complete response (pCR) after neoadjuvant chemotherapy or chemoradiotherapy for locally advanced nonsmall-cell lung cancer (NSCLC). METHODS:Between 1990 and 2004, 211 patients were treated with neoadjuvant ...

journal_title：Cancer

authors： Chen AM,Jahan TM,Jablons DM,Garcia J,Larson DA

更新日期：2007-04-15 00:00:00

abstract：BACKGROUND:The presence of tumor at the inked margins (IMs) of breast specimens is associated with an increased risk of local recurrence after breast-conserving therapy for invasive breast carcinoma and ductal carcinoma in situ (DCIS). Given the importance of margin status, some have advocated the use of shaved margins...

journal_title：Cancer

authors： Guidi AJ,Connolly JL,Harris JR,Schnitt SJ

更新日期：1997-04-15 00:00:00

abstract：:Seventeen cases of intranasal epithelial tumors are reviewed. Thirteen were epithelial papillomas and four were squamous cell carcinomas associated with epithelial papillomas. In two cases followed over a 10 year period, transformation from an initial papilloma into a carcinoma was demonstrated. The histopathologic ca...

journal_title：Cancer

authors： Lasser A,Rothfeld PR,Shapiro RS

更新日期：1976-12-01 00:00:00

abstract：:Small cell carcinoma is primarily a pulmonary neoplasm that rarely arises in extrapulmonic sites including salivary glands of the head and neck. Twelve cases of small cell carcinoma of salivary gland origin were retrieved from the Armed Forces Institute of Pathology files. Six tumors occurred in the parotid gland and ...

journal_title：Cancer

authors： Gnepp DR,Corio RL,Brannon RB

更新日期：1986-08-01 00:00:00

abstract：:Over the last several decades, significant "new eyes" have been developed that improve the diagnosis, treatment, planning, and monitoring of human cancer: computer tomography (CT), magnetic resonance imaging (MRI) and spectroscopy (MRS), single photon emission computed tomography (SPECT), and positron emission tomogra...

journal_title：Cancer

authors： Wagner HN Jr,Conti PS

更新日期：1991-02-15 00:00:00

abstract：:One hundred eighty-three patients with malignant skeletal (83) or soft tissue sarcoma (100) were entered into the multimodality preoperative limb salvage protocol. Local recurrences were observed in 5 of 183 (2.7%). Six patients required amputation because of complications, and 13 patients died within 1 year from meta...

journal_title：Cancer

authors： Eilber FR,Morton DL,Eckardt J,Grant T,Weisenburger T

更新日期：1984-06-15 00:00:00

abstract：:Radiotherapy was applied to 14 esophageal carcinomas with respiratory tract fistulas using various treatment regimens. Closure of the fistulas was observed in four cases after irradiation at a daily dose of 1.5 Gy. The period of closure was transient in two cases but long-term in the other two. One long-term closure c...

journal_title：Cancer

authors： Yamada S,Takai Y,Ogawa Y,Kakuto Y,Sakamoto K

更新日期：1989-09-01 00:00:00

abstract：BACKGROUND:The growth of cancer symptom management research has been limited by challenges of slow recruitment and under-enrollment. One potential solution to this problem is the use of screening questions that identify patients who are interested in participating in research. The goal of this study was to evaluate thi...

journal_title：Cancer

authors： Crowley R,Casarett D

更新日期：2003-05-01 00:00:00

abstract：:The c-Met/hepatocyte growth factor receptor and its family members are known to promote cancer cell migration and invasion. Signaling within and beyond this pathway contributes to the systemic spread of metastases through induction of the epithelial-mesenchymal transition, a process also implicated in mediating resist...

journal_title：Cancer

authors： Bhardwaj V,Cascone T,Cortez MA,Amini A,Evans J,Komaki RU,Heymach JV,Welsh JW

更新日期：2013-05-15 00:00:00

abstract：:Two patients developed extremely bizarre (pseudomalignant) granulation-tissue reactions in the larynx and facial sinuses, following radiation therapy for carcinoma. Containing pleomorphic spindle cells and numerous (sometimes atypical) mitotic figures, both tumefactive lesions simulated high grade malignancies. While ...

journal_title：Cancer

authors： Weidner N,Askin FB,Berthrong M,Hopkins MB,Kute TE,McGuirt FW

更新日期：1987-04-15 00:00:00

abstract：:Renal cell carcinoma (RCC) evokes an immune response, which occasionally has resulted in spontaneous and dramatic remissions. In an attempt to reproduce or accentuate this response, various immunotherapeutic strategies have been studied. The most consistent antitumor activity has been reported with interferon-alpha (I...

journal_title：Cancer

authors： McDermott DF

更新日期：2009-05-15 00:00:00

abstract：:The predictive value of estrogen receptor (ER) level for response to chemotherapy was studied in 182 patients with metastatic breast cancer in a prospective study. Patients were stratified according to ER status and dominant site of disease and randomized to one of three regimens: cyclophosphamide, 5-Fluorouracil, and...

journal_title：Cancer

authors： Rosner D,Lane WW,Nemoto T

更新日期：1989-07-01 00:00:00

abstract：:Twelve cases of ovarian adenocarcinoma were studied for alterations in proto-oncogenes, and a unique pattern of altered ras proto-oncogenes was observed. Amplification of ras-Ki was found in three of seven ovarian tumors and amplification of ras-Ha in one of 12. In contrast, ras-Ha amplification was not found in any o...

journal_title：Cancer

authors： Zhou DJ,Gonzalez-Cadavid N,Ahuja H,Battifora H,Moore GE,Cline MJ

更新日期：1988-10-15 00:00:00

abstract：BACKGROUND:Previous studies have shown that matrix metalloproteinase-2 (MMP-2) (a 72-kilodalton Type IV collagenase/gelatinase A) is associated with breast carcinoma, but to the authors' knowledge there are no reports showing that it is prognostic for overall survival. METHODS:Expression of the immunoreactive protein ...

journal_title：Cancer

authors： Talvensaari-Mattila A,Pääkkö P,Höyhtyä M,Blanco-Sequeiros G,Turpeenniemi-Hujanen T

更新日期：1998-09-15 00:00:00

abstract：:The myeloproliferative neoplasms (MPNs) essential thrombocythemia (ET), polycythemia vera (PV), and primary myelofibrosis (MF) are malignancies that frequently harbor the recurrent somatic point mutation JAK2(V617F). The discovery of this mutation has fueled the development of Janus kinase 2 (JAK2) inhibitors. Availab...

journal_title：Cancer

authors： Quintás-Cardama A,Verstovsek S

更新日期：2012-02-15 00:00:00

abstract：BACKGROUND:Lung carcinoma usually is advanced at the time of presentation and frequently shows metastatic spread. In recent times, prognostic factors such as c-erbB-2 in patients with breast carcinoma have provided useful information and beneficial therapeutic targets. The objective of this study was to evaluate angiog...

journal_title：Cancer

authors： Toomey D,Smyth G,Condron C,Kay E,Conroy R,Foley D,Hong C,Hogan B,Toner S,McCormick P,Broe P,Kelly C,Bouchier-Hayes D

更新日期：2001-11-15 00:00:00

abstract：BACKGROUND:Hispanics comprise almost one-third of the population of California, are the most rapidly increasing racial/ethnic group in the state, and represent almost one-third of all Hispanics in the U.S. California has among the highest rates of melanoma in the world, yet little is known about trends in melanoma in i...

journal_title：Cancer

authors： Cockburn MG,Zadnick J,Deapen D

更新日期：2006-03-01 00:00:00

abstract：:To optimize the prognostic value of DNA flow cytometry in breast cancer the authors calculated several parameters from the DNA histogram, including the DNA index, the size and number of aneuploid peaks as well as S-phase and G2/M-phase cell cycle fractions. Of these, DNA index and S-phase fraction (SPF) proved to be t...

journal_title：Cancer

authors： Kallioniemi OP,Blanco G,Alavaikko M,Hietanen T,Mattila J,Lauslahti K,Lehtinen M,Koivula T

更新日期：1988-11-15 00:00:00