Abstract:
:Thirty-eight patients with metastatic colorecal carcinoma were treated with 5-fluorouracil (5-FU), and 38 patients were treated with the combination of 5-FU, cyclophosphamide, and methotrexate. In terms of percent response, response duration, and survival there was no apparent difference between the two regimens. Combination chemotherapy was found to be effective in 6 of 16 patients refractory to treatment with 5-FU alone, but was associated with more morbidity.
journal_name
Cancerjournal_title
Cancerauthors
Richards F 2nd,Pajak TL,Cooper MR,Spurr CLdoi
10.1002/1097-0142(197511)36:5<1589::aid-cncr282036subject
Has Abstractpub_date
1975-11-01 00:00:00pages
1589-92issue
5eissn
0008-543Xissn
1097-0142journal_volume
36pub_type
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