Synovial sarcoma. A DNA flow cytometric study.

Abstract:

:The relationship between DNA content, clinicopathologic findings, and patient survival in synovial sarcoma was investigated. Patient age at diagnosis (P less than 0.001), tumor size (P less than 0.001), and ploidy status (P less than 0.003) correlated significantly with patient survival. A marginally significant correlation between mitotic count and patient survival was also observed (P = 0.04). Histologic subtypes (monophasic versus biphasic), mitotic count, and S-phase by flow cytometry had no significant influence on the clinical outcome of patients with synovial sarcoma in this study. The authors conclude that DNA ploidy analysis is a significant objective probe in the prognostication of patients with synovial sarcoma.

journal_name

Cancer

journal_title

Cancer

authors

el-Naggar AK,Ayala AG,Abdul-Karim FW,McLemore D,Ballance WW,Garnsey L,Ro JY,Batsakis JG

doi

10.1002/1097-0142(19900515)65:10<2295::aid-cncr282

subject

Has Abstract

pub_date

1990-05-15 00:00:00

pages

2295-300

issue

10

eissn

0008-543X

issn

1097-0142

journal_volume

65

pub_type

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