Body composition in cachexia resulting from malignant and non-malignant diseases.

abstract：BACKGROUND:Thymic malignancies are rare tumors. The insulin-like growth factor-1 (IGF-1)/IGF-1 receptor (IGF-1R) system is involved in the development of the thymus. IGF-1R expression in thymic epithelial malignancies is unknown. METHODS:The authors investigated the expression of IGF-1R and phosphorylated AKT serine 4...

journal_title：Cancer

authors： Zucali PA,Petrini I,Lorenzi E,Merino M,Cao L,Di Tommaso L,Lee HS,Incarbone M,Walter BA,Simonelli M,Roncalli M,Santoro A,Giaccone G

更新日期：2010-10-15 00:00:00

abstract：:In the past few years, the role of membrane-bound transport genes in human disease has been increasingly recognized and understood. Of these genes, the p170 membrane glycoprotein may function as an outward transport pump for many cancer chemotherapeutic drugs associated with the multidrug resistance phenotype. This ar...

journal_title：Cancer

authors： Leyland-Jones B,Dalton W,Fisher GA,Sikic BI

更新日期：1993-12-01 00:00:00

abstract：:Numerous examples exist of prognostic factors that have been conclusively established and that can segregate the target patient population into subgroups with vastly different outcomes. At the same time, we can expect, in the majority of trials being conducted, that if a new treatment turns out to be successful, it ge...

journal_title：Cancer

authors： Sather HN

更新日期：1986-07-15 00:00:00

abstract：BACKGROUND:Some vasoactive drugs have been studied in the hope of altering the vascular permeability and/or blood of tumors to enhance monoclonal antibody (MoAb) uptake. The pretreatment of interleukin-2 (IL-2), one of the vasoactive reagents, produced a generalized vascular permeability, but its function was not tumor...

journal_title：Cancer

authors： Nakamura K,Kubo A

更新日期：1997-12-15 00:00:00

abstract：:Findings from 1665 women with primary breast cancer, treated at 34 NSABP institutions in Canada and the United States, have failed to demonstrate that patients with medial-central tumors had a greater probability of developing distant metastases or dying than did those with lateral tumors despite the greater incidence...

journal_title：Cancer

authors： Fisher B,Wolmark N,Redmond C,Deutsch M,Fisher ER

更新日期：1981-10-15 00:00:00

abstract：:Twenty-four patients who developed extramedullary disease during the course of Philadelphia chromosome-positive chronic myelogenous leukemia are described. The most frequent sites of extramedullary disease were lymph nodes (54%), bone (37%), and skin and soft tissue (29%). The appearance of extramedullary disease was ...

journal_title：Cancer

authors： Terjanian T,Kantarjian H,Keating M,Talpaz M,McCredie K,Freireich EJ

更新日期：1987-01-15 00:00:00

abstract：BACKGROUND:The demonstration of the monoclonality of immunoglobulin heavy chain (IgH) gene rearrangement is an indispensable method for the diagnosis of B-cell lymphoma as well as histocytochemical analysis. For the detection of IgH gene rearrangement, the extraction of DNA from a homogenous cell population is necessar...

journal_title：Cancer

authors： Orba Y,Tanaka S,Nishihara H,Kawamura N,Itoh T,Shimizu M,Sawa H,Nagashima K

更新日期：2003-08-25 00:00:00

abstract：BACKGROUND:Oral tongue cancer incidence has increased among whites in the United States; however, the cause remains unknown. If an infectious agent is implicated, then elevated risk would be expected among immunosuppressed individuals. METHODS:By using population-based registry linkage information from the US Transpla...

journal_title：Cancer

authors： Tota JE,Engels EA,Madeleine MM,Clarke CA,Lynch CF,Ortiz AP,Hernandez BY,Chaturvedi AK

更新日期：2018-06-15 00:00:00

abstract：BACKGROUND:Extrapulmonary inflammatory pseudotumor (plasma cell granuloma) is an uncommon lesion in adults and children, and little is known either of its etiology or clinical characteristics. However, it remains a significant source of morbidity to patients and confusion to clinicians. METHODS:Case reports are presen...

journal_title：Cancer

authors： Treissman SP,Gillis DA,Lee CL,Giacomantonio M,Resch L

更新日期：1994-03-01 00:00:00

abstract：BACKGROUND:We investigated p16(INK4A) expression in branchial cleft cysts and its utility in distinguishing branchial cleft cysts from metastatic head and neck squamous cell carcinomas (SCCs) in fine-needle aspiration biopsies (FNABs). METHODS:A study set comprising 41 resections (15 SCC and 26 branchial cleft cysts) ...

journal_title：Cancer

authors： Pai RK,Erickson J,Pourmand N,Kong CS

更新日期：2009-04-25 00:00:00

abstract：BACKGROUND:The objective of this study was to describe characteristics at diagnosis and outcomes of adults with soft tissue sarcoma. METHODS:The authors conducted a retrospective multicenter study of 12,262 patients who were treated between January 1980 and 31 December 2013 in French Sarcoma Group centers and enrolled...

journal_title：Cancer

authors： Penel N,Coindre JM,Giraud A,Terrier P,Ranchere-Vince D,Collin F,Guellec SLE,Bazille C,Lae M,de Pinieux G,Ray-Coquard IL,Bonvalot S,Cesne ALE,Robin YM,Stoeckle E,Toulmonde M,Blay JY

更新日期：2018-03-15 00:00:00

abstract：BACKGROUND:Cytology and core-needle biopsies are not always sufficient to exclude malignancy in benign breast lesions (BBL) that are at risk of developing cancer, and open biopsy often is mandatory. In screening programs, open biopsies performed for lesions that are at risk of developing malignancy are considered benig...

journal_title：Cancer

authors： Manfrin E,Mariotto R,Remo A,Reghellin D,Falsirollo F,Dalfior D,Bricolo P,Piazzola E,Bonetti F

更新日期：2009-02-01 00:00:00

abstract：BACKGROUND:The growth of cancer symptom management research has been limited by challenges of slow recruitment and under-enrollment. One potential solution to this problem is the use of screening questions that identify patients who are interested in participating in research. The goal of this study was to evaluate thi...

journal_title：Cancer

authors： Crowley R,Casarett D

更新日期：2003-05-01 00:00:00

abstract：:The discovery that the human papilloma virus (HPV) is associated with a high and increasing percentage of oropharyngeal squamous cell carcinomas (SCCs) is among the most significant advances in the field of head and neck oncology. HPV-positive oropharyngeal cancer (HPVOPC) has clinical, etiologic, pathologic, and mole...

journal_title：Cancer

authors： Urban D,Corry J,Rischin D

更新日期：2014-05-15 00:00:00

abstract：BACKGROUND:Late menarche, early menopause, high parity, and early first birth decrease the risk of development of breast cancer. The influence of these factors on the survival of breast cancer patients has not been explained. METHODS:A group of 1885 patients with operable breast cancer was studied retrospectively. A u...

journal_title：Cancer

authors： Korzeniowski S,Dyba T

更新日期：1994-09-01 00:00:00

abstract：BACKGROUND:Meeting quality of care standards in oncology is recognized as important by physicians, professional organizations, and payers. Data from a population-based cohort of patients with prostate cancer were used to examine whether receipt of care was consistent with published consensus metrics and whether receivi...

journal_title：Cancer

authors： Holmes JA,Bensen JT,Mohler JL,Song L,Mishel MH,Chen RC

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:In this study, the authors evaluated the clinical presentation of patients with T4b breast carcinoma, analyzed the impact of noninflammatory skin involvement on long-term survival, and addressed the question whether the T4 tumor category still has any justification. METHODS:The clinical course of a study gr...

journal_title：Cancer

authors： Guth U,Wight E,Schotzau A,Langer I,Dieterich H,Rochlitz C,Herberich L,Holzgreve W,Singer G

更新日期：2005-11-01 00:00:00

abstract：:Chemotherapy once relegated to end stage patients has markedly improved with the use of combinations. Response rates with single agents have improved from 15 to 35%, to 50 to 70%, using combinations with an increase in complete response rates to about 25%. A series of four studies completed by the Eastern Cooperative ...

journal_title：Cancer

authors： Carbone PP,Bauer M,Band P,Tormey D

更新日期：1977-06-01 00:00:00

abstract：BACKGROUND:Surveillance, Epidemiology, and End Results (SEER) data are frequently used to examine receipt of adjuvant radiotherapy (RT), but to the authors' knowledge the accuracy of data regarding second-course treatments is unknown. METHODS:Using SEER-Medicare-linked data, the authors identified a cohort of men who ...

journal_title：Cancer

authors： Wang K,Sheets NC,Basak R,Chen RC

更新日期：2016-10-01 00:00:00

abstract：:In 1988, the International Federation of Gynecology and Obstetrics (FIGO) Cancer Committee changed the staging of endometrial carcinoma from a clinical one to a surgicopathologic one. The emphasis in the new FIGO system was changed to the pathologic findings in the uterus, cervix, adnexa, and pelvic and/or periaortic ...

journal_title：Cancer

authors： Mikuta JJ

更新日期：1993-02-15 00:00:00

abstract：BACKGROUND:This survey documents the strategies used by pain control physicians in the selection of opioid drugs and routes of administration in the management of inpatients referred to a cancer pain service. METHODS:The following approaches were prospectively evaluated during the treatment of 100 consecutive inpatien...

journal_title：Cancer

authors： Cherny NJ,Chang V,Frager G,Ingham JM,Tiseo PJ,Popp B,Portenoy RK,Foley KM

更新日期：1995-10-01 00:00:00

abstract：BACKGROUND:Histologic response to chemotherapy has been shown to be an independent prognostic factor in patients with osteosarcoma and Ewing sarcoma. However, in patients with soft tissue sarcoma (STS), the prognostic impact of histologic response to chemotherapy is less clear. In the current study, the authors sought ...

journal_title：Cancer

authors： Mullen JT,Hornicek FJ,Harmon DC,Raskin KA,Chen YL,Szymonifka J,Yeap BY,Choy E,DeLaney TF,Nielsen GP

更新日期：2014-12-01 00:00:00

abstract：:Urinary polyamine concentrations in 91 samples were assayed in 79 patients with malignant melanoma who were classified as to clinical stage, as well as to activity of disease. Patients with active disease had higher mean polyamine values, increased frequency of polyamine elevations, and increased frequency of two or m...

journal_title：Cancer

authors： Townsend RM,Banda PW,Marton LJ

更新日期：1976-11-01 00:00:00

abstract：:Fourteen examples of intravenous leiomyomatosis in the FIP files were studied. Growth beyond the uterus occurred in 10 of the 14 examples, largely in vessels in the broad ligament and in uterine and iliac veins. Metastasis to the heart occurred in 1 example. The study provides evidence that is consistent with both the...

journal_title：Cancer

authors： Norris HJ,Parmley T

更新日期：1975-12-01 00:00:00

abstract：:Trabecular carcinoma of the skin (Merkel cell tumor), a neoplasm of putative neural origin, must be differentiated from other small cell tumors primary or metastatic to skin. In order to provide more objective diagnostic criteria, four were examined using monoclonal antibodies against neurofilament proteins (NF) and a...

journal_title：Cancer

authors： Leff EL,Brooks JS,Trojanowski JQ

更新日期：1985-08-01 00:00:00

abstract：:Hepatoid adenocarcinomas of the stomach are gastric carcinomas with both adenocarcinomatous and hepatocellular differentiations. They usually produce large amounts of alpha-fetoprotein (AFP) with a Concanavalin A-binding property of hepatic type. In this study, these carcinomas occurred in older persons, with the antr...

journal_title：Cancer

authors： Ishikura H,Kirimoto K,Shamoto M,Miyamoto Y,Yamagiwa H,Itoh T,Aizawa M

更新日期：1986-07-01 00:00:00

abstract：:Six patients with Hodgkin's disease (HD) and demonstrable serum antibodies to human immunodeficiency virus (HIV) and two additional patients with HD belonging to HIV-associated high-risk groups but with negative HIV serology were studied. All patients were men and ranged in age from 21 to 45 years. The HIV risk factor...

journal_title：Cancer

authors： Pelstring RJ,Zellmer RB,Sulak LE,Banks PM,Clare N

更新日期：1991-04-01 00:00:00

abstract：BACKGROUND:Multimodality treatment has dramatically improved the outcome of patients with Ewing sarcoma. However, there appears to be little information concerning treatment-related complications in patients who are long-term survivors. METHODS:Forty-one patients with Ewing sarcoma who were treated between 1960-1980 a...

journal_title：Cancer

authors： Fuchs B,Valenzuela RG,Inwards C,Sim FH,Rock MG

更新日期：2003-12-15 00:00:00

abstract：:The DNA stemline ploidy was assessed in paraffin-embedded, formalin-fixed primary tumor tissue from 68 patients with nonseminomatous germ cell cancer (NSCGT) clinical Stage I (CS I). Forty-three patients had a single aneuploid (greater than 1C) DNA stemline, whereas 24 patients had multiple aneuploid stemlines. In one...

journal_title：Cancer

authors： Fosså SD,Nesland JM,Waehre H,Amellem O,Pettersen EO

更新日期：1991-04-01 00:00:00

abstract：BACKGROUND:Bone morphogenetic proteins (BMP) induce ectopic bone formation in vivo and may play a role in normal bone development. In addition, bone morphogenetic activity, as measured in a bone-forming assay in immunodeficient, athymic nu/nu mice, is present in a proportion of osteosarcomas; this activity, which may b...

journal_title：Cancer

authors： Yoshikawa H,Rettig WJ,Takaoka K,Alderman E,Rup B,Rosen V,Wozney JM,Lane JM,Huvos AG,Garin-Chesa P

更新日期：1994-01-01 00:00:00