Abstract:
BACKGROUND:Extrapulmonary inflammatory pseudotumor (plasma cell granuloma) is an uncommon lesion in adults and children, and little is known either of its etiology or clinical characteristics. However, it remains a significant source of morbidity to patients and confusion to clinicians. METHODS:Case reports are presented of three patients with intraabdominal inflammatory pseudotumor who recently underwent surgery. A review of the recent world literature is also presented. Clinical and laboratory characteristics of omental-mesenteric inflammatory pseudotumor are reviewed along with a discussion of its etiology. RESULTS:Cytogenetic data from cells of one patient show a derivative chromosome evolved from a translocation between the long arm of chromosome 2 and the short arm of chromosome 9 [(2;9)(q1,3;p2,2)]. CONCLUSIONS:The lesion is monoclonal, and genetic changes may play a crucial role in the development of this neoplasm. Omental-mesenteric inflammatory pseudotumor appears to represent a distinct clinicopathologic entity as a benign neoplasm in children.
journal_name
Cancerjournal_title
Cancerauthors
Treissman SP,Gillis DA,Lee CL,Giacomantonio M,Resch Ldoi
10.1002/1097-0142(19940301)73:5<1433::aid-cncr2820subject
Has Abstractpub_date
1994-03-01 00:00:00pages
1433-7issue
5eissn
0008-543Xissn
1097-0142journal_volume
73pub_type
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