Abstract:
:The experience of 260 patients with endometrial carcinoma was reviewed. The influence of factors such as age, stage of disease, grade and degree of myometrial penetration on the survival was presented, showing that survival decreases in elderly patients, in patients with advanced stage of disease, when the tumor is undifferentiated, and when the tumor deeply penetrates the myometrium. The methods of therapy, fall into three main groups: surgery, radiotherapy, and combined therapy, the latter yielding the best 5-year survival rate, in all stages. The incidence of vaginal recurrences was low, probably due to the fact that 68.8% of the patients were treated by a combined therapeutic modality.
journal_name
Cancerjournal_title
Cancerauthors
Tavares MA,Patricio MB,Vilhena M,Da Silva JNdoi
10.1002/1097-0142(197702)39:2<675::aid-cncr2820390subject
Has Abstractpub_date
1977-02-01 00:00:00pages
675-80issue
2eissn
0008-543Xissn
1097-0142journal_volume
39pub_type
杂志文章相关文献
CANCER文献大全abstract:BACKGROUND:Colorectal carcinoma is the second most common cause of cancer death with African Americans having lower survival compared with White Americans. The purpose of this study was to investigate the effect of demographics, clinical factors, and socioeconomic status (SES) on racial disparities in colorectal cancer...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.24408
更新日期:2009-08-15 00:00:00
abstract::Two patients with superior vena cava syndrome (SVCS) recurring after maximum-tolerance radiation were treated by placing a Gianturco expandable wire stent (GEWS) into the obstructed superior vena cava. The SVCS symptoms rapidly disappeared and good short-term (6 months) palliation was achieved. GEWS placement is a pro...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19870915)60:6<1243::aid-cncr2820
更新日期:1987-09-15 00:00:00
abstract:BACKGROUND:CD133 is a specific surface marker for bone marrow-derived circulating endothelial progenitors, which are vital in postnatal physiologic and pathologic (eg, tumor) angiogenesis. In this study, the authors examined whether increased levels of expression of CD133 messenger RNA (mRNA) in peripheral blood predic...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.22774
更新日期:2007-08-01 00:00:00
abstract::A prospective study of four cycles of etoposide with ifosfamide and cisplatin (VIP) chemotherapy was conducted in 42 germ cell tumor (GCT) patients who were refractory to cisplatin with etoposide/vinblastine-based therapy. Forty patients were evaluable for response. Ten patients (25%) had a complete response: seven to...
journal_title:Cancer
pub_type: 临床试验,杂志文章
doi:10.1002/1097-0142(19901215)66:12<2476::aid-cncr282
更新日期:1990-12-15 00:00:00
abstract:BACKGROUND:Peritoneal metastases are one reason for the poor prognosis of scirrhous gastric cancer. However, the mechanism of peritoneal metastasis remains unclear. We therefore investigated the interaction between gastric cancer cells and peritoneal fibroblasts, in vivo and in vitro. METHODS:A human scirrhous gastric...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/(SICI)1097-0142(19960415)77:8<1668::AID-CN
更新日期:1996-04-15 00:00:00
abstract::Clinical, histological and ultrastructural features of three small cell carcinomas arising in the parotid gland are presented. The light microscopic appearance of two of the neoplasms suggested neuroendocrine cell derivation, confirmed by electron microscopy in both instances. The fine structure of the third neoplasm ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19831201)52:11<2115::aid-cncr282
更新日期:1983-12-01 00:00:00
abstract:BACKGROUND:Preclinical studies have demonstrated that the inhibition of the PI3K/Akt/mTOR pathway restores gefitinib sensitivity in resistant cancer cell lines. A phase 1 study was conducted of the combination of everolimus, an mTOR inhibitor, and gefitinib to determine a daily dose of everolimus with gefitinib in pati...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.22816
更新日期:2007-08-01 00:00:00
abstract::Four courses of ifosfamide with mesna given by intravenous infusions were combined with bolus doxorubicin in a phase II trial to treat patients with breast cancer. Ifosfamide can deplete intracellular glutathione levels and because doxorubicin resistance may be associated with elevated levels of intracellular glutathi...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19900601)65:11<2421::aid-cncr282
更新日期:1990-06-01 00:00:00
abstract::Granular cell tumor of the stomach is rare and may occur in association with similar tumors in the skin. Two such tumors were found in association with cutaneous granular cell tumors in two black females. Infiltrating carcinoma of the stomach was suspected at surgery in one case. All of the lesions were typical granul...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19840515)53:10<2104::aid-cncr282
更新日期:1984-05-15 00:00:00
abstract::Two human Burkitt's lymphoma cell lines (HBL-4 and HBL-5) were established individually from two patients with small noncleaved cell lymphoma (Burkitt's type). The HBL-4 cell line is Epstein-Barr virus (EBV)-negative, and the HBL-5 cell line is EBV-positive. Cytogenetically, both cell lines had the same chromosomal tr...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19920201)69:3<763::aid-cncr28206
更新日期:1992-02-01 00:00:00
abstract:BACKGROUND:The unknown etiology of endometrioid carcinomas of the ovary and the relatively high frequency of a concomitant carcinoma of the endometrium in these patients warrants study of such tumors. The aim of this study was to identify the genetic alterations involved in endometrioid ovarian cancer development, and ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19950815)76:4<650::aid-cncr28207
更新日期:1995-08-15 00:00:00
abstract:BACKGROUND:Monitoring therapy in patients with brain tumors is very difficult and unreliable. It has been shown that there is no good correlation between tumor sensitivity measured in vitro and in situ tumor response to therapies. METHODS:Sequential changes in tumor size, number of DNA synthesizing cells (labelling in...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/(sici)1097-0142(19960315)77:6<1167::aid-cn
更新日期:1996-03-15 00:00:00
abstract::The cellular DNA content in colorectal biopsies from 51 patients with chronic ulcerative colitis has been studied with flow-cytometric technique. The DNA pattern has been related to the duration of the disease, and to histopathology. Aneuploid cell lines were found in eight patients, two of which had histopathological...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19840115)53:2<291::aid-cncr28205
更新日期:1984-01-15 00:00:00
abstract:BACKGROUND:Parathyroid hormone-related protein (PTHrP) is the predominant cause of humoral hypercalcemia of malignancy (HHM). METHODS:Using a PTHrP-specific monoclonal antibody (MoAb), 4B3, the authors investigated the immunohistochemical localization of PTHrP in formalin-fixed and paraffin-embedded sections of normal...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19930501)71:9<2803::aid-cncr2820
更新日期:1993-05-01 00:00:00
abstract:BACKGROUND:There is limited published evidence regarding the efficacy of total skin electron beam radiation for patients with the diffuse erythrodermic form of mycosis fungoides. METHODS:Forty-five patients with erythrodermic mycosis fungoides were managed at McMaster University in Hamilton, Ontario, Canada (n=34), an...
journal_title:Cancer
pub_type: 临床试验,杂志文章
doi:10.1002/(sici)1097-0142(19990501)85:9<1985::aid-cn
更新日期:1999-05-01 00:00:00
abstract:BACKGROUND:Myoepithelial carcinoma, also know as malignant myoepithelioma, is rare in the salivary gland, and its cytologic features have rarely been reported. DESIGN:Four cases of myoepithelial carcinoma with cytology were retrieved from the archives of the Pathology Departments of two academic institutes. In three c...
journal_title:Cancer
pub_type: 杂志文章
doi:
更新日期:2002-02-25 00:00:00
abstract:BACKGROUND:Reliable predictive biomarkers are required to address the challenge of disease recurrence after thyroid cancer surgery. For this study, the authors assessed the association of cellular-based and serum-based immunologic mediators with thyroid cancer recurrence. METHODS:Leukocyte subset counts and immune reg...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.27937
更新日期:2013-04-15 00:00:00
abstract:BACKGROUND:Hospital services are expectantly reduced over the weekend, which may result in a delay in treatment or in obtainment of medical procedures. The authors investigated quality of care and clinical outcomes of newly diagnosed acute myeloid leukemia (AML) patients who were hospitalized on weekends versus weekday...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.25086
更新日期:2010-08-01 00:00:00
abstract::To determine whether steroid hormone receptor expression is clinically relevant in ovarian cancer, cytoplasmic and nuclear estrogen (ER) and progesterone (PR) receptor levels have been measured and their concentration calculated by Scatchard analysis. Of 89 samples from patients with non-pretreated epithelial ovarian ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19900201)65:3<486::aid-cncr28206
更新日期:1990-02-01 00:00:00
abstract:BACKGROUND:Telomerase activity and telomere length have been shown to be involved in the control of cell proliferation and regulation of cell senescence. The expression of telomerase activity may endow cells with the capacity of unlimited proliferation and immortality. The authors examined the telomerase activity and t...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(20001115)89:10<2092::aid-cncr9>3
更新日期:2000-11-15 00:00:00
abstract::Indomethacin (prostaglandin synthetase inhibitor) was found to be capable of enhancing the mitogen-induced lymphocyte proliferative responses of healthy subjects and patients with lung cancer. A whole-blood culture technique was used. Indomethacin had no mitogenic activity. We observed a greater enhancement of lymphoc...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19801201)46:11<2416::aid-cncr282
更新日期:1980-12-01 00:00:00
abstract:BACKGROUND:Low-dose computed tomography (LDCT) lung screening has been associated with a 20% reduction in lung cancer mortality. A major barrier to the adoption of lung screening is the potential negative psychological impact of a false-positive (FP) screen, occurring in 20% to 50% of those screened. The objective of t...
journal_title:Cancer
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1002/cncr.28833
更新日期:2014-11-01 00:00:00
abstract::A 17 year old man with a primary intracranial germ cell tumor in the pituitary region is reported. Both serum alpha-fetoprotein (AFP) and serum human chorionic gonadotropin (hCG) were found elevated preoperatively. Normal levels of serum AFP and hCG were found after operation and radiotherapy. By indirect immunofluore...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(197806)41:6<2315::aid-cncr282041
更新日期:1978-06-01 00:00:00
abstract::Forty-four patients with advanced carcinoma of the head and neck were treated with cyclophosphamide, 400 mg/m2 plus BCNU, 100 mg/m2 day 1 followed by adriamycin 40 mg/m2 day 2, with therapy repeated every 4 weeks. Of 31 evaluable patients, there were 1 complete response, and 10 partial responses (35%). Four of 8 patie...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(197911)44:5<1571::aid-cncr282044
更新日期:1979-11-01 00:00:00
abstract:BACKGROUND:This study was undertaken to determine whether the use of intermediate dose methotrexate in combination with vinblastine, doxorubicin, and cisplatin as first-line therapy increases the proportion of major responders and overall survival in patients with unresectable or metastatic transitional cell carcinoma ...
journal_title:Cancer
pub_type: 临床试验,杂志文章
doi:10.1002/(sici)1097-0142(19990301)85:5<1145::aid-cn
更新日期:1999-03-01 00:00:00
abstract:BACKGROUND:Rising health care costs have caused providers to question the benefit of regular follow-up after treatment for patients with early stage cutaneous melanoma. The authors hypothesized that routine reassessment and careful education of these patients would facilitate earlier diagnosis of a subsequent second pr...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(20010415)91:8<1520::aid-cncr1160
更新日期:2001-04-15 00:00:00
abstract::In order to search for the histogenesis and progression of colorectal cancer, the background mucosas of 18 patients with a single colorectal cancer, apart from familial adenomatosis coli, were studied by a step sectioning method. Three early minute cancers (3-5 mm in diameter) were detected in the apparently normal mu...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19880215)61:4<829::aid-cncr28206
更新日期:1988-02-15 00:00:00
abstract::The presentation, growth patterns, and response to therapy of 11 consecutive children with choroid plexus carcinomas were analyzed, and the results were compared with the outcome reported in other series. Patients were a median of 26 months of age at diagnosis. Two patients had thalamic tumors, one had a posterior fos...
journal_title:Cancer
pub_type: 杂志文章,评审
doi:10.1002/1097-0142(19920115)69:2<580::aid-cncr28206
更新日期:1992-01-15 00:00:00
abstract::Sixteen patients with metastatic neuroendocrine tumors and the malignant carcinoid syndrome were treated with cyproheptadine (Periactin, Merck, Sharp & Dohme, West Point, PA) at maximum tolerable doses that ranged from 12 to 48 mg daily. Usual side effects were mild sedation and dry mouth, but three patients found it ...
journal_title:Cancer
pub_type: 临床试验,杂志文章
doi:10.1002/1097-0142(19910101)67:1<33::aid-cncr282067
更新日期:1991-01-01 00:00:00
abstract:BACKGROUND:Topotecan is a topoisomerase I inhibitor that has good penetration across the blood-brain barrier and significant antitumor activity against human brain tumor xenografts. In a Phase I trial in children with refractory cancer, topotecan was well tolerated when administered as a 24-hour infusion. The maximum t...
journal_title:Cancer
pub_type: 临床试验,杂志文章
doi:10.1002/(SICI)1097-0142(19960801)78:3<527::AID-CNC
更新日期:1996-08-01 00:00:00