Cancer in collagen disease. A statistical analysis by reviewing the Annual of Pathological Autopsy Cases (Nippon Boken Shuho) in Japan.

Abstract:

:Cases of systemic lupus erythematosus, systemic sclerosis, periarteritis nodosa, and dermato- and polymyositis autopsied in Japan during a recent, 7-year period (1972-1978) were studied to assess the incidence of cancer as a complication. In comparison with the other three groups, cases of dermato- and polymyositis (DP) showed quite a high incidence of malignancy: 53 of 99 for males (53.5%) and 36 of 139 for females (25.9%). In patients older than 50 years of age cancer was recognized in the autopsies of 65.7% of males and 38.2% of females with DP. The stomach was both the primary site and had the highest incidence of cancers in DP (62.3% males, 27.8% females). It was concluded that DP has a strong association with the development of cancer, particularly gastric carcinoma, in Japan.

journal_name

Cancer

journal_title

Cancer

authors

Okayasu I,Mizutani H,Kurihara H,Yanagisawa F

doi

10.1002/1097-0142(19841101)54:9<1841::aid-cncr2820

subject

Has Abstract

pub_date

1984-11-01 00:00:00

pages

1841-4

issue

9

eissn

0008-543X

issn

1097-0142

journal_volume

54

pub_type

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