Breast carcinoma presenting as axillary metastases without evidence of a primary tumor.

abstract：:A staging system was proposed for chronic myeloid leukemia (CML) that groups patients into three stages (I, II, and III), each with two subclasses (A and B). The system uses pathologic parameters, of which the percentage of blasts in the blood and bone marrow is the most important. CML is defined as a myeloproliferati...

journal_title：Cancer

authors： Ross DW,Brunning RD,Kantarjian HM,Koeffler HP,Ozer H

更新日期：1993-06-01 00:00:00

abstract：BACKGROUND:For patients who have chondrosarcoma with unresectable disease, because of tumor location, tumor size, or extensive metastatic disease, treatment options are very limited because of their relative resistance to radiotherapy and chemotherapy. The overall survival of this patient population is poor; however, s...

journal_title：Cancer

authors： van Maldegem AM,Gelderblom H,Palmerini E,Dijkstra SD,Gambarotti M,Ruggieri P,Nout RA,van de Sande MA,Ferrari C,Ferrari S,Bovée JV,Picci P

更新日期：2014-10-15 00:00:00

abstract：:Sixty patients with advanced prostatic carcinoma were treated with monthly subcutaneous injections of a depot formulation of goserelin, a luteinizing hormone-releasing hormone (LHRH) analogue (Zoladex, ICI Pharma, Destelbergen, Belgium). All patients were regularly evaluated with measurements of luteinizing hormone (L...

journal_title：Cancer

authors： Mahler C,Verhelst J,Chaban M,Denis L

更新日期：1991-02-01 00:00:00

abstract：:This study examines the interrelationships of depth of penetration, tumor size, and the number of positive nodes in Dukes C colorectal cancer. The results indicated that depth of tumor penetration was related to both tumor size and the number of positive regional lymph nodes. Tumors with positive nodes which failed to...

journal_title：Cancer

authors： Wolmark N,Fisher ER,Wieand HS,Fisher B

更新日期：1984-06-15 00:00:00

abstract：BACKGROUND:Older women are less likely than younger women to receive definitive care for a new diagnosis of breast cancer, but the reasons are not well understood. Although coordination of referral among specialists is an important component of quality of care, it has not been studied as a factor that contributes to ob...

journal_title：Cancer

authors： Thwin SS,Fink AK,Lash TL,Silliman RA

更新日期：2005-09-01 00:00:00

abstract：BACKGROUND:Ifosfamide has previously been shown to be active as a single agent and in combination with doxorubicin, etoposide, and teniposide in pediatric solid tumors and adult acute leukemia. The authors performed a dose-escalation trial of ifosfamide with a fixed dosage of etoposide, with mesna uroprotection, in chi...

journal_title：Cancer

authors： Bernstein ML,Whitehead VM,Devine S,Grier H,Kung F,Krischer J,Dreyer Z,Bell B,Land V,Buchanan GR

更新日期：1993-09-01 00:00:00

abstract：:The authors investigated the level of lipid peroxidation and possible related phenomena in the activation of phospholipase A2 and the infiltration of granulocyte neutrophils in human colorectal cancer tissue samples. Malondialdehyde (an index of lipid peroxidation), phospholipase A2 activity, and myeloperoxidase activ...

journal_title：Cancer

authors： Otamiri T,Sjödahl R

更新日期：1989-07-15 00:00:00

abstract：:The authors discovered some errors regarding reference group labels in Table 2. The corrected table is attached. The authors regret these errors. ...

journal_title：Cancer

authors：

更新日期：2015-03-01 00:00:00

abstract：:Postmenopausal patients with metastatic breast cancer were treated with medroxyprogesterone acetate (MPA) (Clinovir) in dosages between 500 and 1500 mg orally per day. The relation of MPA plasma concentrations and endocrine effects were studied in a longitudinal fashion. MPA exerted suppressive effects on the basal an...

journal_title：Cancer

authors： Blossey HC,Wander HE,Koebberling J,Nagel GA

更新日期：1984-09-15 00:00:00

abstract：BACKGROUND:China's lung cancer (LC) burden plays a pivotal role in the global cancer epidemic. Comparing LC burden and population attributable fractions (PAFs) of risk factors between China and other countries/regions is essential to inform effective intervention. The Global Burden of Disease (GBD) study provides a uni...

journal_title：Cancer

authors： Wang N,Mengersen K,Tong S,Kimlin M,Zhou M,Hu W

更新日期：2020-09-15 00:00:00

abstract：:Solitary extramedullary plasmacytomas are rare tumors, reported to occur most commonly in the upper respiratory passages, but which also are rarely seen in the middle and lower gastrointestinal system. This report documents the first primary plasmacytoma of the esophagus. A 67-year-old Caucasian man complained of dysp...

journal_title：Cancer

authors： Ahmed N,Ramos S,Sika J,LeVeen HH,Piccone VA

更新日期：1976-08-01 00:00:00

abstract：:Fifty-four patients with advanced squamous, large-cell or adeno-carcinoma of the lung were treated with a three drug regimen of high-dose cisplatin, vindesine and a four-day bleomycin infusion (CVB). All patients had measurable disease; none had previously received chemotherapy. Of 52 patients evaluable for response, ...

journal_title：Cancer

authors： Itri LM,Gralla RJ,Kelsen DP,Chapman RA,Casper ES,Braun DW Jr,Howard JE,Golbey R,Heelan RT

更新日期：1983-03-15 00:00:00

abstract：BACKGROUND:Glioblastoma, which is the most malignant brain tumor, remains incurable and almost always causes death. As a new treatment strategy, the combination of all-trans retinoic acid (ATRA) and paclitaxel was explored for controlling the growth of glioblastoma U87MG xenografts. METHODS:Human glioblastoma U87MG xe...

journal_title：Cancer

authors： Karmakar S,Banik NL,Ray SK

更新日期：2008-02-01 00:00:00

abstract：:Flow cytometry was used to compare binding of wheat germ agglutinin (WGA) and Lens culinaris lectin (Lcl) to peripheral lymphocytes (PBL) from normal subjects and 26 patients with chronic lymphocytic leukemia (CLL). As defined by the interactions of WGA and Lcl with cell surface receptors, normal unfractionated PBL an...

journal_title：Cancer

authors： Boldt DH,Nelson MO

更新日期：1983-06-01 00:00:00

abstract：BACKGROUND:The incidence of rectal cancer in the United States in young patients is considered to be low. Underestimating this incidence may result in a failure to diagnose younger patients with rectal cancer in a timely manner. METHODS:The authors conducted a retrospective cohort study using Surveillance, Epidemiolog...

journal_title：Cancer

authors： Meyer JE,Narang T,Schnoll-Sussman FH,Pochapin MB,Christos PJ,Sherr DL

更新日期：2010-09-15 00:00:00

abstract：BACKGROUND:The purpose of the study was to determine the utility of quantitation of the extracellular domain (ECD) of the HER-2/neu receptor in the serum for predicting response to treatment in patients with primary breast cancer receiving neoadjuvant therapy. METHODS:HER-2/neu ECD was measured in sera obtained from 3...

journal_title：Cancer

authors： Mazouni C,Hall A,Broglio K,Fritsche H,Andre F,Esteva FJ,Hortobagyi GN,Buzdar AU,Pusztai L,Cristofanilli M

更新日期：2007-02-01 00:00:00

abstract：BACKGROUND:Workload is extensively regulated and often used as a measure of quality in gynecologic cytology. Whether workload correlates with the sensitivity of screening in gynecologic cytology is not known. METHODS:The sensitivity of gynecologic cytology screening was measured over an 8-month period using the result...

journal_title：Cancer

authors： Deschenes M,Renshaw AA,Auger M

更新日期：2008-06-25 00:00:00

abstract：:A large lipoma and a large angiomyolipoma of the liver, one case each, are described. In the first case, a 24 X 14-cm homogeneous mass demonstrated a fatty density (-96H) on computed tomography (CT), echogenicity on sonography, and fine neovascular vessels on angiography in the right lobe of the liver. Histopathologic...

journal_title：Cancer

authors： Takayasu K,Shima Y,Muramatsu Y,Moriyama N,Yamada T,Makuuchi M,Hirohashi S

更新日期：1987-03-01 00:00:00

abstract：BACKGROUND:Heparanase up-regulation has been correlated with reduced postoperative survival in various cancers. METHODS:Heparanase expression was analyzed in 60 consenting tongue (mobile) cancer patients by means of immunohistochemistry. Heparanase levels were also analyzed in the saliva of both healthy controls and t...

journal_title：Cancer

authors： Nagler R,Ben-Izhak O,Cohen-Kaplan V,Shafat I,Vlodavsky I,Akrish S,Ilan N

更新日期：2007-12-15 00:00:00

abstract：:Four courses of ifosfamide with mesna given by intravenous infusions were combined with bolus doxorubicin in a phase II trial to treat patients with breast cancer. Ifosfamide can deplete intracellular glutathione levels and because doxorubicin resistance may be associated with elevated levels of intracellular glutathi...

journal_title：Cancer

authors： Millward MJ,Harris AL,Cantwell BM

更新日期：1990-06-01 00:00:00

abstract：BACKGROUND:The authors hypothesized that comprehensive genomic profiling of advanced-stage cutaneous squamous cell carcinoma (cSCC) could identify genomic-derived drug targets of therapy for patients with conventional therapy-resistant disease. METHODS:Comprehensive genomic profiling of 315 cancer genes was applied to...

journal_title：Cancer

authors： Al-Rohil RN,Tarasen AJ,Carlson JA,Wang K,Johnson A,Yelensky R,Lipson D,Elvin JA,Vergilio JA,Ali SM,Suh J,Miller VA,Stephens PJ,Ganesan P,Janku F,Karp DD,Subbiah V,Mihm MC,Ross JS

更新日期：2016-01-15 00:00:00

abstract：:The efficacy of trioxifene mesylate, a new antiestrogen, in the management of advanced breast cancer was evaluated in 69 patients. Fifty-two patients were randomly allocated to dose schedules of 5 mg, 10 mg, and 20 mg orally twice daily. There were five complete responders (10%), 22 partial responders (42%), and 9 pat...

journal_title：Cancer

authors： Lee RW,Buzdar AU,Blumenschein GR,Hortobagyi GN

更新日期：1986-01-01 00:00:00

abstract：BACKGROUND:Investigations regarding the impact of tumor biology after surgical management of colorectal liver metastasis have focused largely on overall survival. We investigated the impact of codon-specific KRAS mutations on the rates and patterns of recurrence in patients after surgery for colorectal liver metastasis...

journal_title：Cancer

authors： Margonis GA,Kim Y,Sasaki K,Samaha M,Amini N,Pawlik TM

更新日期：2016-09-01 00:00:00

abstract：BACKGROUND:Paclitaxel currently is administered by prolonged intravenous infusion because of the occurrence of severe hypersensitivity reactions in patients in early clinical trials. However, intensive premedication probably is more important in eliminating allergic reactions than is the length of infusion. The authors...

journal_title：Cancer

authors： Hainsworth JD,Greco FA

更新日期：1994-08-15 00:00:00

abstract：:Low-dose continuous infusion 5-fluorouracil (LDCI-FU) was administered to 28 women with advanced breast carcinoma. Daily doses ranged from 175 to 250 mg/m2. The LDCI-FU was delivered continuously until the appearance of toxicity and was reinstituted at a 20% dose reduction after toxicity completely resolved. Patients ...

journal_title：Cancer

authors： Huan S,Pazdur R,Singhakowinta A,Samal B,Vaitkevicius VK

更新日期：1989-02-01 00:00:00

abstract：:Irreversible and progressive renal parenchymal damage and functional impairment occurred in the majority of patients receiving at least six courses (200 mg/m2 of BCNU and/or methyl CCNU at eight-week intervals) of nitrosoureas for therapy of malignant brain tumors. Seventeen of 18 patients who received at least six co...

journal_title：Cancer

authors： Schacht RG,Feiner HD,Gallo GR,Lieberman A,Baldwin DS

更新日期：1981-09-15 00:00:00

abstract：:This report describes a case of null cell congenital acute lymphoblastic leukemia associated with a (4;11) translocation. This chromosome abnormality is associated with acute lymphoblastic leukemia and probably more specifically with congenital acute lymphoblastic leukemia. A review of the literature is presented. ...

journal_title：Cancer

authors： Esseltine DW,Vekemans M,Seemayer T,Reece E,Gordon J,Whitehead VM

更新日期：1982-08-01 00:00:00

abstract：:Treatment of 91 consecutive patients having metastatic, Stage IV melanoma who had not received any previous chemotherapy was begun between January 1977 and April 1978. The therapy included bleomycin (B) at 7.5 units subcutaneously in the first course and 15 units in subsequent courses on days 1 and 4; vincristine or O...

journal_title：Cancer

authors： Seigler HF,Lucas VS Jr,Pickett NJ,Huang AT

更新日期：1980-12-01 00:00:00

abstract：:Chondrosarcoma of the temporal bone is a rare lesion. Clinically it has been confused with multiple sclerosis, glomus jugulare tumors, meningioma, and chordomas. The cranial nerve palsies frequently observed with the tumors are related to the anatomic locations of the tumors. Thirteen patients with this entity are pre...

journal_title：Cancer

authors： Coltrera MD,Googe PB,Harrist TJ,Hyams VJ,Schiller AL,Goodman ML

更新日期：1986-12-15 00:00:00

abstract：BACKGROUND:The authors previously identified sperm protein 17 (Sp17) as being expressed in patients with multiple myeloma. The restricted expression of Sp17 in normal tissue makes it an ideal target for tumor vaccine. In the current study, the authors extended their research to include ovarian carcinoma. METHODS:A pai...

journal_title：Cancer

authors： Chiriva-Internati M,Wang Z,Salati E,Timmins P,Lim SH

更新日期：2002-05-01 00:00:00