A proposed staging system for chronic myeloid leukemia.

Abstract:

:A staging system was proposed for chronic myeloid leukemia (CML) that groups patients into three stages (I, II, and III), each with two subclasses (A and B). The system uses pathologic parameters, of which the percentage of blasts in the blood and bone marrow is the most important. CML is defined as a myeloproliferative disorder with molecular or cytogenetic evidence of the translocation of the abl oncogene on chromosome 9 to the break-point cluster region gene on chromosome 22. The proposed staging system is similar to format to the standard TNM system used for many solid tumors.

journal_name

Cancer

journal_title

Cancer

authors

Ross DW,Brunning RD,Kantarjian HM,Koeffler HP,Ozer H

doi

10.1002/1097-0142(19930601)71:11<3788::aid-cncr282

subject

Has Abstract

pub_date

1993-06-01 00:00:00

pages

3788-91

issue

11

eissn

0008-543X

issn

1097-0142

journal_volume

71

pub_type

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