Abstract:
:A staging system was proposed for chronic myeloid leukemia (CML) that groups patients into three stages (I, II, and III), each with two subclasses (A and B). The system uses pathologic parameters, of which the percentage of blasts in the blood and bone marrow is the most important. CML is defined as a myeloproliferative disorder with molecular or cytogenetic evidence of the translocation of the abl oncogene on chromosome 9 to the break-point cluster region gene on chromosome 22. The proposed staging system is similar to format to the standard TNM system used for many solid tumors.
journal_name
Cancerjournal_title
Cancerauthors
Ross DW,Brunning RD,Kantarjian HM,Koeffler HP,Ozer Hdoi
10.1002/1097-0142(19930601)71:11<3788::aid-cncr282subject
Has Abstractpub_date
1993-06-01 00:00:00pages
3788-91issue
11eissn
0008-543Xissn
1097-0142journal_volume
71pub_type
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