Distinct genome-wide methylation patterns in sporadic and hereditary nonfunctioning pancreatic neuroendocrine tumors.

abstract：BACKGROUND:This study was conducted to determine the efficacy and safety of irinotecan (CPT-11) as second-line therapy in patients with advanced cervical carcinoma. METHODS:Sixteen patients with platinum-resistant squamous cell carcinoma were treated with CPT-11 as second-line therapy. CPT-11 was administered in repea...

journal_title：Cancer

authors： Irvin WP,Price FV,Bailey H,Gelder M,Rosenbluth R,Durivage HJ,Potkul RK

更新日期：1998-01-15 00:00:00

abstract：BACKGROUND:Modern cancer treatments can cure or prolong patients' lives. However, the associated physical and psychosocial problems can detrimentally affect patients' compliance with treatment and, ultimately, their outcomes. Therefore, oncologists need to recognize the problems experienced by their patients and, when ...

journal_title：Cancer

authors： Newell S,Sanson-Fisher RW,Girgis A,Bonaventura A

更新日期：1998-10-15 00:00:00

abstract：:To assess the importance of radiation dose fraction size in the treatment of malignant melanomas, the records of 48 patients (83 sites) treated at Tufts-New England Medical Center from 1971 to 1979 have been retrospectively reviewed. During this period, the dose fractionation schemes evolved from standard fraction siz...

journal_title：Cancer

authors： Strauss A,Dritschilo A,Nathanson L,Piro AJ

更新日期：1981-03-15 00:00:00

abstract：:Few epidemiologic studies have been undertaken to investigate the etiology of cancer of the vulva. To identify risk factors associated with this cancer, a case-control study was conducted in 149 patients with histologically proven vulvar carcinoma and the same number of control patients matched for age, race, marital ...

journal_title：Cancer

authors： Mabuchi K,Bross DS,Kessler II

更新日期：1985-04-15 00:00:00

abstract：:In a series of 643 patients with small cell lung cancer (SCLC), 55 patients (8.6%) had signs or symptoms of superior vena caval obstruction syndrome (SVCO). Relatively long intervals from the onset of the first symptoms of SVCO to the start of therapy were observed, and invasive diagnostic procedures were safely perfo...

journal_title：Cancer

authors： Sculier JP,Evans WK,Feld R,DeBoer G,Payne DG,Shepherd FA,Pringle JF,Yeoh JL,Quirt IC,Curtis JE

更新日期：1986-02-15 00:00:00

abstract：:We have demonstrated by tissue assay and immunohistochemical techniques that tumor cells appear to be the source of the increased histaminase activity found in 60% of ascitic fluids from patients with ovarian carcinoma. The histaminase activity in 64% of tumor tissues studied was greater than 100 U/g of tissue, a valu...

journal_title：Cancer

authors： Ettinger DS,Rosenshein NB,Parmley TH,Mendelsohn G,Baylin SB

更新日期：1980-05-15 00:00:00

abstract：:Central nervous system (CNS) recurrence continues to be a significant complication in the treatment of adult patients with acute lymphoblastic leukemia (ALL). Preventing CNS recurrence has been a therapeutic challenge and has not been addressed critically in many clinical trials. Adult studies modeled on childhood ALL...

journal_title：Cancer

authors： Jabbour E,Thomas D,Cortes J,Kantarjian HM,O'Brien S

更新日期：2010-05-15 00:00:00

abstract：:A case of a patient with a metastatic ACTH (adrenocorticotrophic hormone)-producing gastric carcinoid APUD (amine precursor uptake and decarboxylation) tumor is presented. The patient presented with Cushing's syndrome and very high levels of ACTH. The Cushing's syndrome was controlled medically, and when the patient d...

journal_title：Cancer

authors： Marcus FS,Friedman MA,Callen PW,Churg A,Harbour J

更新日期：1980-09-01 00:00:00

abstract：BACKGROUND:A combination regimen comprised of docetaxel, gemcitabine, and granulocyte-colony stimulating factor (G-CSF) was studied in patients with advanced nonsmall cell lung carcinoma (NSCLC) to determine its antitumor efficacy and tolerance. METHODS:Thirty-four patients with advanced measurable NSCLC (3 patients w...

journal_title：Cancer

authors： Hejna M,Kornek GV,Raderer M,Ulrich-Pur H,Fiebiger WC,Marosi L,Schneeweiss B,Greul R,Scheithauer W

更新日期：2000-08-01 00:00:00

abstract：BACKGROUND:The authors conducted a comprehensive review of the efficacy of 2-deoxy-2-[F-18]fluoro-D-glucose positron emission tomography (FDG-PET) in the detection of primary tumors in patients with disseminated carcinoma of unknown primary site. METHODS:Ten studies (involving a total of 221 patients) tat were publish...

journal_title：Cancer

authors： Sève P,Billotey C,Broussolle C,Dumontet C,Mackey JR

更新日期：2007-01-15 00:00:00

abstract：BACKGROUND:To evaluate the pathologic characteristics of the primary tumor relative to local control, survival, and freedom from distant metastases, an analysis was performed of 172 patients with ductal carcinoma in situ (intraductal carcinoma) of the breast treated with breast-conserving surgery and definitive breast ...

journal_title：Cancer

authors： Solin LJ,Yeh IT,Kurtz J,Fourquet A,Recht A,Kuske R,McCormick B,Cross MA,Schultz DJ,Amalric R

更新日期：1993-04-15 00:00:00

abstract：BACKGROUND:Nonsteroidal anti-inflammatory drugs (NSAIDs) may prevent the development of cancer by inhibiting cyclooxygenase (COX) enzymes, which are involved in carcinogenesis. Therefore, the authors of this report examined the association between NSAID use and the risk of squamous cell carcinoma (SCC), basal cell carc...

journal_title：Cancer

authors： Johannesdottir SA,Chang ET,Mehnert F,Schmidt M,Olesen AB,Sørensen HT

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:Screening over many years is required to optimize reductions in colorectal cancer (CRC) mortality. However, no prior trials have compared strategies for obtaining long-term adherence. METHODS:Systems of Support to Increase Colorectal Cancer Screening and Follow-Up was implemented in an integrated health car...

journal_title：Cancer

authors： Green BB,Anderson ML,Cook AJ,Chubak J,Fuller S,Meenan RT,Vernon SW

更新日期：2017-11-15 00:00:00

abstract：:The immunologic phenotypes of 59 cases of diffuse, aggressive, non-Hodgkin's lymphomas were determined using a battery of immunologic and cytochemical techniques. Included were cases of diffuse, large cell "histiocytic," mixed cell, undifferentiated non-Burkitt's. Burkitt's lymphoma, lymphoblastic lymphoma, and mycosi...

journal_title：Cancer

authors： Cossman J,Jaffe ES,Fisher RI

更新日期：1984-10-01 00:00:00

abstract：BACKGROUND:Complementary medicine has become an important aspect of palliative cancer care. This overview is primarily aimed at providing guidance to clinicians regarding some commonly used complementary therapies. METHODS:Several complementary therapies were identified as particularly relevant to palliative cancer ca...

journal_title：Cancer

authors： Ernst E

更新日期：2001-06-01 00:00:00

abstract：:One hundred thirty-five hepatocellular carcinomas were examined for the presence of antigenic tumor markers by the avidin-biotin-peroxidase complex method. Ninety-seven were from the US and 38 came from Argentina. The following markers were tested: alpha-fetoprotein (AFP), alpha-1-antitrypsin (AAT), hepatitis B surfac...

journal_title：Cancer

authors： Chedid A,Chejfec G,Eichorst M,Villamil F,Terg R,Telenta M,Hojman R

更新日期：1990-01-01 00:00:00

abstract：:The reports of 240 gallium scans on 165 patients with Hodgkin's disease were reviewed to compare results with higher doses with those in earlier studies that employed lower doses. Tracer concentrations in specific sites were correlated with radiologic and pathologic reports and with the clinical courses of the patient...

journal_title：Cancer

authors： Hagemeister FB,Fesus SM,Lamki LM,Haynie TP

更新日期：1990-03-01 00:00:00

abstract：BACKGROUND:Methotrexate is a chemotherapeutic agent frequently utilized for the treatment of malignant, rheumatic, and pulmonary diseases. Although this agent has been extensively used for more than 45 years, there are few reports of immediate systemic hypersensitivity reactions. The reported immediate reactions includ...

journal_title：Cancer

authors： Alkins SA,Byrd JC,Morgan SK,Ward FT,Weiss RB

更新日期：1996-05-15 00:00:00

abstract：:Using a modified Feulgen hydrolysis procedure and integrating microdensitometry, the acid-labile nuclear DNA in exfoliated cervical epithelial cells was quantified in a range of histologically confirmed cervical intraepithelial neoplasia (CIN), invasive cancer, and normal controls. The mean relative optical densities ...

journal_title：Cancer

authors： Partington CK,Sincock AM,Steele SJ

更新日期：1991-06-15 00:00:00

abstract：BACKGROUND:There is limited information on outcomes of prostate carcinoma treatments given to screened patient populations for whom cancer is usually detected at an earlier stage. METHODS:The authors conducted a cross-sectional evaluation of quality-of-life outcomes for men with prostate carcinoma detected in screenin...

journal_title：Cancer

authors： Smith DS,Carvalhal GF,Schneider K,Krygiel J,Yan Y,Catalona WJ

更新日期：2000-03-15 00:00:00

abstract：:Over the years, there has been a continuous increase in clinically relevant driver mutations in patients with non-small cell lung cancer (NSCLC). Among these, dysregulated activation of the MET tyrosine kinase receptor has gained importance due to the recent development of quite effective treatments. MET dysregulation...

journal_title：Cancer

authors： Friedlaender A,Drilon A,Banna GL,Peters S,Addeo A

更新日期：2020-11-15 00:00:00

abstract：:Breast reconstruction is not a new idea. Techniques have been developing since the late 1800s. The state of the art is such that the knowledge of its availability and success has significant effect on the willingness of women to seek earlier diagnosis and treatment. However, reconstruction is not for everyone. This pa...

journal_title：Cancer

authors： Brown HG

更新日期：1991-09-01 00:00:00

abstract：BACKGROUND:A prospective, randomized study was performed to determine the efficacy of neoadjuvant chemotherapy over radiotherapy alone in patients with locally advanced nasopharyngeal carcinoma. METHODS:From January 1991 to December 1998, 80 patients were enrolled in this study. Patients with locoregional carcinoma of...

journal_title：Cancer

authors： Hareyama M,Sakata K,Shirato H,Nishioka T,Nishio M,Suzuki K,Saitoh A,Oouchi A,Fukuda S,Himi T

更新日期：2002-04-15 00:00:00

abstract：:CA 125 and steroid production is compared in a group of 48 women with ovarian epithelial carcinoma. The histologic types were I C (n = 20), II C (n = 5), III C (n = 11), or V (n = 12). The number of patients in Stage I was six; Stage II, 11; Stage III, 16; and Stage IV, 15. All patients were naturally or surgically po...

journal_title：Cancer

authors： Mählck CG,Grankvist K,Kjellgren O,Bäckström T

更新日期：1990-05-01 00:00:00

abstract：:The entire colonic mucosa of 51 cases of colorectal carcinoma was examined histologically. Mucosal lesions including goblet cell hyperplasia, crypt dilatation, ulceration with regeneration, basal cell hyperplasia, metaplastic lesions, and adenomas were encountered. Goblet cell hyperplasia (80.4%) was most prominent ad...

journal_title：Cancer

authors： Lee YS

更新日期：1988-04-15 00:00:00

abstract：BACKGROUND:Patients with renal masses are at risk for having or developing chronic kidney disease (CKD) stage 3 (glomerular filtration rate [GFR] <60 mL per minute/1.73 m2). In this study, the authors investigated whether the Screening for Occult Renal Disease (SCORED) model could identify patients with renal masses wh...

journal_title：Cancer

authors： Lucas SM,Nuss G,Stern J,Lotan Y,Sagalowsky AI,Cadeddu JA,Raj GV

更新日期：2008-11-15 00:00:00

abstract：BACKGROUND:Human neoplasms often are accompanied by an inflammatory infiltrate. It has been proposed that this represents an immunologic response to the tumor. Dysgerminoma, a germ cell tumor of the ovary, is a classic example of this phenomenon. The authors investigated the immunophenotype of the tumor-infiltrating ly...

journal_title：Cancer

authors： Dietl J,Horny HP,Ruck P,Kaiserling E

更新日期：1993-04-15 00:00:00

abstract：BACKGROUND:An increase in resting energy expenditure (REE) is considered to contribute to the weight loss experienced by patients with cancer. However, alternations in basal metabolism vary among patients with different neoplasms. REE in patients with hepatocellular carcinoma (HCC), a common malignant tumor in Taiwan, ...

journal_title：Cancer

authors： Chen WJ,Chung YC

更新日期：1994-02-01 00:00:00

abstract：:The purpose of this study is to evaluate benign and/or malignant thyroid tumors with 201TI thyroid scan. We studied 76 cases of histologically verified thyroid tumors, all seen as cold nodules on the 123I thyroid scan. 201TI thyroid scan was performed 5-15 minutes (early scan) and 3-5 hours (delayed scan) after intrav...

journal_title：Cancer

authors： Ochi H,Sawa H,Fukuda T,Inoue Y,Nakajima H,Masuda Y,Okamura T,Onoyama Y,Sugano S,Ohkita H,Tei Y,Kamino K,Kobayashi Y

更新日期：1982-07-15 00:00:00

abstract：BACKGROUND:The association between hormone replacement therapy (HRT) and a reduced lung cancer risk has been reported in previous studies. There is a high female to male ratio in Chinese lung cancer patients, and female patients have different clinicopathological characteristics compared with Western patient population...

journal_title：Cancer

authors： Chen KY,Hsiao CF,Chang GC,Tsai YH,Su WC,Perng RP,Huang MS,Hsiung CA,Chen CJ,Yang PC,GEFLAC Study Group.

更新日期：2007-10-15 00:00:00