Abstract:
:A case of a patient with a metastatic ACTH (adrenocorticotrophic hormone)-producing gastric carcinoid APUD (amine precursor uptake and decarboxylation) tumor is presented. The patient presented with Cushing's syndrome and very high levels of ACTH. The Cushing's syndrome was controlled medically, and when the patient deteriorated clinically she received treatment with a combination of BCNU, adriamycin, and ftorafur. She responded dramatically with marked clinical improvement and normalization of plasma ACTH levels. The current status of the APUD cell concept is discussed, with its overall implications for treatment of this group of malignancies.
journal_name
Cancerjournal_title
Cancerauthors
Marcus FS,Friedman MA,Callen PW,Churg A,Harbour Jdoi
10.1002/1097-0142(19800901)46:5<1263::aid-cncr2820subject
Has Abstractpub_date
1980-09-01 00:00:00pages
1263-9issue
5eissn
0008-543Xissn
1097-0142journal_volume
46pub_type
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