Abstract:
:From April 1985 through March 1988, 24 lung cancer patients with carcinomatous pleuritis were treated with a new combined treatment modality consisting of pulmonary resection and postoperative intrathoracic chemo-thermotherapy (PICT). They consisted of 15 male patients and nine female patients. A majority of the patients (79%%) had adenocarcinoma. The PICT was started 10 to 14 days after the operation. Immediately after a bolus intrathoracic injection of cisplatin (CDDP) 50-100 mg, thermotherapy was carried out using 13.56-MHz or 8.00-MHz radiofrequency waves for 60 minutes. The peripleural temperature was precisely monitored in 20 patients. The temperature was successfully maintained above 42 degrees C for 40 minutes in each of two or three treatment courses in 13 patients, with no complications. However, in the other seven patients the therapy resulted in incomplete treatment because of development of a side effect. Cytologic examination of the pleural effusion, which was performed after the completion of PICT, gave a negative result in 16 of 20 patients examined. The median follow-up period was 16 months. Local relapse was recognized in only three cases who received incomplete treatment or in whom no temperature measurement was performed. The overall survival of the treated patients (n = 24) was significantly prolonged in comparison with a historical control group treated by surgery only (n = 17) or exploratory thoracotomy (n = 11). Of those 17 patients treated by surgery only, ten patients (59%) died of local relapse. These results suggest that this new treatment modality consisting of pulmonary resection and PICT is useful for the treatment of lung cancer patients with carcinomatous pleuritis, especially in the light of improved local control.
journal_name
Cancerjournal_title
Cancerauthors
Kodama K,Doi O,Tatsuta M,Kuriyama K,Tateishi Rdoi
10.1002/1097-0142(19891001)64:7<1422::aid-cncr2820subject
Has Abstractpub_date
1989-10-01 00:00:00pages
1422-8issue
7eissn
0008-543Xissn
1097-0142journal_volume
64pub_type
杂志文章相关文献
CANCER文献大全abstract:BACKGROUND:The objective of this study was to describe characteristics at diagnosis and outcomes of adults with soft tissue sarcoma. METHODS:The authors conducted a retrospective multicenter study of 12,262 patients who were treated between January 1980 and 31 December 2013 in French Sarcoma Group centers and enrolled...
journal_title:Cancer
pub_type: 杂志文章,多中心研究
doi:10.1002/cncr.31176
更新日期:2018-03-15 00:00:00
abstract::Since primary lymphoma of bone (PLB) exhibits morphologic diversity and variability in individual survival, we analyzed the relationship between histopathologic features and biological behavior in 33 patients treated at the Massachusetts General Hospital. Three major histologic subgroups were identified, based on a va...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19820901)50:5<1009::aid-cncr2820
更新日期:1982-09-01 00:00:00
abstract:BACKGROUND:The aim of this study was to determine and compare the added prognostic value of screening tools, geriatric assessment (GA) components, and GA summaries to clinical information for overall survival (OS) in older patients with cancer. METHODS:A screening and a 10-item GA were systematically performed in pati...
journal_title:Cancer
pub_type: 杂志文章,多中心研究
doi:10.1002/cncr.31581
更新日期:2018-09-15 00:00:00
abstract:BACKGROUND:Gastrin-releasing peptide (GRP) is an autocrine growth factor in patients with small cell lung carcinoma (SCLC). The authors developed a reverse transcriptase-polymerase chain reaction (RT-PCR) assay for the detection of SCLC cells in the peripheral blood and the pleural effusion using preproGRP mRNA as a ta...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.11378
更新日期:2003-05-15 00:00:00
abstract::Fifty patients with metastatic breast cancer were treated with a combination of vincristine, Adriamycin and prednisolone (VAP) at four weekly intervals. Response rates of 78% for soft tissue disease, 66% for parenchymal lung disease, 67% for liver disease, and 64% for pleural effusions were seen. Only 26% of patients ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(197802)41:2<396::aid-cncr2820410
更新日期:1978-02-01 00:00:00
abstract:BACKGROUND:Cancer affects patients' incomes, but to the authors' knowledge few studies to date have examined how the income of the patients' spouses may be influenced. In this population-based study from Norway, the effects of cancer on both partners' earnings are analyzed. METHODS:The difference between labor earning...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.24582
更新日期:2009-09-15 00:00:00
abstract:BACKGROUND:Whether patient navigation improves outcomes for patients with comorbidities is unknown. The aims of this study were to determine the effect of comorbidities on the time to diagnostic resolution after an abnormal cancer screening test and to examine whether patient navigation improves the timeliness and like...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.30316
更新日期:2017-01-01 00:00:00
abstract::One promising area of current research in chemoprevention is the possibility that micronutrients, including vitamin A analogues, may decrease cancer incidence. The term "vitamin A" refers either to retinol (preformed vitamin A) and its synthetic analogues, or to certain carotenoids (provitamin A), which are converted ...
journal_title:Cancer
pub_type: 临床试验,杂志文章
doi:10.1002/1097-0142(19861015)58:8+<1837::aid-cncr282
更新日期:1986-10-15 00:00:00
abstract::Serum trace elements (STE) were measured in 50 patients with chronic lymphocytic leukemia (CLL) and 100 normal subjects. Copper was higher in patients than in controls (1.50 +/- 0.06 versus 1.10 +/- 0.02 micrograms/ml, P less than 0.001), increased steadily from Stage 0 to Stage 4 (P = 0.002), and correlated with the ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19871015)60:8<1842::aid-cncr2820
更新日期:1987-10-15 00:00:00
abstract:BACKGROUND:For many childhood cancers, survival is lower among non-Hispanic blacks and Hispanics in comparison with non-Hispanic whites, and this may be attributed to underlying socioeconomic factors. However, prior childhood cancer survival studies have not formally tested for mediation by socioeconomic status (SES). ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.31560
更新日期:2018-10-15 00:00:00
abstract::Tumor-associated antigens (TAA) excreted into the urine of sarcoma patients can be detected by the complement-fixation assay. The authors prospectively measured TAA levels in the urine of 50 sarcoma patients postoperatively to determine whether reappearance of antigen in the urine would be predictive of disease recurr...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19840315)53:6<1306::aid-cncr2820
更新日期:1984-03-15 00:00:00
abstract::Malignant schwannomas with rhabdomyoblastic differentiation have been termed malignant "Triton" tumors (MTT). To define the natural history of MTT, we have analyzed our experience (9 cases, the largest series reported) in combination with the 27 previously described in the literature (total 36 cases). This study was i...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19850601)55:11<2543::aid-cncr282
更新日期:1985-06-01 00:00:00
abstract::A new method of arterially administering an oily anticancer agent was successfully established for the selective targeting of metastatic lymph nodes. A high molecular weight anticancer agent, a conjugate of copolymer (styrene maleic acid) to neocarzinostatin (SMANCS) was prepared in our laboratory and dissolved in a l...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19870501)59:9<1560::aid-cncr2820
更新日期:1987-05-01 00:00:00
abstract:BACKGROUND:The stabilization and nuclear translocation of beta-catenin are early events in the majority of sporadic colorectal carcinomas (CRC). beta-catenin up-regulates c-Myc and cyclin D1, which antagonize the association of the cyclin-dependent kinase (Cdk) inhibitor, p27(kip1), with Cdk2, thus allowing cell cycle ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.10986
更新日期:2002-12-15 00:00:00
abstract::Although weight loss has an adverse impact on cancer patient survival, the ability of caloric provision via total parenteral nutrition (TPN) to favorably influence outcome in chemotherapy-treated populations is not established. In randomized trials, no significant improvement in either response or survival was associa...
journal_title:Cancer
pub_type: 临床试验,杂志文章,评审
doi:10.1002/1097-0142(19850101)55:1+<268::aid-cncr2820
更新日期:1985-01-01 00:00:00
abstract:BACKGROUND:Ewing sarcoma family of tumors (ESFTs) are the second most common bone tumor, that most often affects persons ages 3-40 years. The ESFTs rely on signaling through the insulin-like growth factor-1 receptor (IGF-1R) for growth and transformation. The current studies were performed to determine the levels of IG...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(20011201)92:11<2941::aid-cncr100
更新日期:2001-12-01 00:00:00
abstract:BACKGROUND:Nilotinib is a potent, second-generation inhibitor of BCR-ABL1 tyrosine kinase and has been approved as frontline and salvage therapy for patients with chronic-phase chronic myeloid leukemia (CP-CML). METHODS:In this single-institution, phase 2 study, 122 patients with newly diagnosed CP-CML received niloti...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.32623
更新日期:2020-04-01 00:00:00
abstract:BACKGROUND:We have often encountered difficulties in identifying small liver cancers during surgery. Fluorescent imaging using indocyanine green (ICG) has the potential to detect liver cancers through the visualization of the disordered biliary excretion of ICG in cancer tissues and noncancerous liver tissues compresse...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.24291
更新日期:2009-06-01 00:00:00
abstract:BACKGROUND:Immediate or early postmastectomy breast reconstruction is performed infrequently. To the authors' knowledge, little is known regarding surgeon or patient perspectives on reconstruction treatment decisions. The purpose of the current study was to identify patient attitudes and preferences associated with bre...
journal_title:Cancer
pub_type: 杂志文章,多中心研究
doi:10.1002/cncr.21444
更新日期:2005-12-01 00:00:00
abstract:BACKGROUND:Commission on Cancer data from the National Cancer Data Base (NCDB) report time trends in stage of disease, treatment patterns, and survival for patients with selected cancers. The most current data (1993) for patients with colon cancer are described. METHODS:Five calls for data yielded 3,700,000 cases of c...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/(SICI)1097-0142(19960815)78:4<918::AID-CNC
更新日期:1996-08-15 00:00:00
abstract::A solitary tumor which by light microscopy was calssified as a neurofibroma was found by electron microscopic study to be composed of parallel, elongate cells with collagen rich intervening matrix. The cells showed thin, polar cytoplasmic processes which extended long distances, frequent junctional complexes between c...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(197805)41:5<1823::aid-cncr282041
更新日期:1978-05-01 00:00:00
abstract:BACKGROUND:Primary lymphomas of the uterus or cervix are so rare that treatment series of single institutions consist of very small numbers of patients, making standard treatment difficult to define. The outcome of patients treated with a combination of chemotherapy and radiation therapy was analyzed for all but patien...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19950501)75:9<2392::aid-cncr2820
更新日期:1995-05-01 00:00:00
abstract::Immunomorphologic methods were utilized to localize adenosine deaminase (ADA) in extrathymic benign lymphoid tissues and B-cell lymphomas. In reactive lymph nodes, tonsils and appendix, germinal centers displayed strong ADA-positive nuclear staining in small cleaved lymphocytes and weak nuclear and/or cytoplasmic stai...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19840101)53:1<70::aid-cncr282053
更新日期:1984-01-01 00:00:00
abstract::Despite proven benefits of neoadjuvant chemotherapy in patients with locally advanced, invasive breast cancer, no regimen is recommended as the treatment of choice. Neoadjuvant chemotherapy regimens encompass single-agent and combination therapy and sequential treatment. For this report, the author reviewed the litera...
journal_title:Cancer
pub_type: 杂志文章,评审
doi:10.1002/cncr.23083
更新日期:2007-12-01 00:00:00
abstract:BACKGROUND:Tumor volume in radical prostatectomies can be determined by several different techniques and appears to predict clinical progression. Greatest tumor dimension and area are easily obtained measures that are both correlated with tumor volume. The authors sought to determine whether greatest tumor dimension an...
journal_title:Cancer
pub_type: 杂志文章
doi:
更新日期:1998-08-15 00:00:00
abstract:BACKGROUND:The objective of this study was to estimate the time to treatment failure and survival rate of the three-drug combination of doxorubicin, cisplatin, and ifosfamide as primary and postoperative, adjunctive treatment for teenagers and adults with osteosarcoma (OS). METHODS:Sixty-three eligible patients with n...
journal_title:Cancer
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1002/cncr.20021
更新日期:2004-02-15 00:00:00
abstract::A series of 108 prospectively collected human pancreata were evaluated histologically for the presence of acinar cell and ductal lesions. Foci of dysplastic acinar cells were present in 44% of the series. Some of the focal acinar cell abnormalities were similar to atypical acinar cell nodules which have been described...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19800201)45:3<534::aid-cncr28204
更新日期:1980-02-01 00:00:00
abstract::There are few cases of catecholamine-secreting paragangliomas of the neck reported in the literature, most of these being of the carotid body and glomus-jugulare type. This report cites the second case of a functioning vagal body tumor secreting norepinephrine predominantly and producing labile hypertension and sympto...
journal_title:Cancer
pub_type: 杂志文章,评审
doi:10.1002/1097-0142(19830901)52:5<932::aid-cncr28205
更新日期:1983-09-01 00:00:00
abstract:BACKGROUND:The American Joint Committee on Cancer (AJCC) 7th edition introduced major changes in the staging of lung cancer, including the tumor (T), node (N), metastasis (M)-TNM-system and new stage/prognostic site-specific factors (SSFs), collected under the Collaborative Stage Version 2 (CSv2) Data Collection System...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.29045
更新日期:2014-12-01 00:00:00
abstract::A primary cardiac spindle cell tumor with immunoreactivity for keratin proteins is reported. Cytogenetic analysis of the tumor demonstrated a translocation (X;18), an aberration almost exclusively reported in synovial sarcomas. Postmortem examination revealed amphibole asbestos within the lungs and diaphragmatic pleur...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19940101)73:1<74::aid-cncr282073
更新日期:1994-01-01 00:00:00