Relation of comorbidities and patient navigation with the time to diagnostic resolution after abnormal cancer screening.

abstract：BACKGROUND:The authors report the long-term treatment results for advanced stage base of tongue (BOT) and tonsillar fossa (TF) carcinomas treated with surgery and postoperative radiation therapy (RT) at Memorial Sloan-Kettering Cancer Center. METHODS:Between 1973 and 1986, 51 patients with squamous cell carcinoma of t...

journal_title：Cancer

authors： Zelefsky MJ,Harrison LB,Armstrong JG

更新日期：1992-11-15 00:00:00

abstract：BACKGROUND:The influence of HER-2/neu on prognosis of breast cancer is controversial. The authors investigated by immunohistochemistry in node-positive disease the influence of the pattern of immunostaining (membranous or cytoplasmic) on outcome and the prognostic significance of this marker in patients receiving or no...

journal_title：Cancer

authors： Têtu B,Brisson J

更新日期：1994-05-01 00:00:00

abstract：BACKGROUND:Previously published studies concerning autopsy findings in ovarian cancer failed to consider the broad differences in factors that influence the course of disease. Furthermore, those studies were conducted when the currently accepted standards in diagnostics and therapy had not been fully established. The o...

journal_title：Cancer

authors： Güth U,Huang DJ,Bauer G,Stieger M,Wight E,Singer G

更新日期：2007-09-15 00:00:00

abstract：:In three cases of the spontaneous rupture of hepatocellular carcinoma, emergent transcatheter hepatic arterial embolization was performed for controlling the intraperitoneal hemorrhage. No more transfusions were required after embolization. Operation was carried out on the 10th, 5th, and 5th day, respectively, after l...

journal_title：Cancer

authors： Chen MF,Jan YY,Lee TY

更新日期：1986-07-15 00:00:00

abstract：:A series of eight plasma cell granulomas of the lung were examined. Their clinical, pathologic, and immunohistochemical characteristics as well as the ultrastructural features of one case are in agreement with those found in the literature. One patient died after a surgical intervention complicated by invasion of pulm...

journal_title：Cancer

authors： Warter A,Satge D,Roeslin N

更新日期：1987-02-01 00:00:00

abstract：:Grilled or fried meat and fish contain various mutagenic heterocyclic amines, and structures of at least 19 compounds have already been determined. Among these, 10 have been examined for long term carcinogenicity, all proving to be positive. 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP), for example, preferen...

journal_title：Cancer

authors： Nagao M,Ushijima T,Wakabayashi K,Ochiai M,Kushida H,Sugimura T,Hasegawa R,Shirai T,Ito N

更新日期：1994-08-01 00:00:00

abstract：:Blood was obtained on 414 occasions from 106 children with acute lymphocytic leukemia (ALL) or solid tumors. Resting and stimulated hexose monophosphate shunt (HMPS) activity and unstimulated and stimulated nitroblue tetrazolium (NBT) dye reduction were assessed on each sample. The values obtained were compared to sim...

journal_title：Cancer

authors： Pickering LK,Anderson DC,Choi S,Feigin RD

更新日期：1975-05-01 00:00:00

abstract：:A short-term differential staining cytotoxicity (DiSC) assay was used to assess the sensitivity of tumor cells in vitro from patients with chronic lymphocytic leukemia (CLL) and non-Hodgkin's lymphoma to various cytotoxic drugs. The results have been correlated with drug sensitivities of the tumors in vivo. The chemos...

journal_title：Cancer

authors： Bird MC,Bosanquet AG,Forskitt S,Gilby ED

更新日期：1988-03-15 00:00:00

abstract：:Survivors of pediatric and young adult cancers remain at risk for subsequent diseases, including those related to human papillomavirus (HPV) infection. Prevention of HPV acquisition through vaccination has become possible over the last decade. HPV vaccines have been shown to be safe and effective, yet rates of vaccina...

journal_title：Cancer

authors： Temkin SM,Seibel NL

更新日期：2015-10-01 00:00:00

abstract：:A new approach using anthropometric, radiographic, biochemical, and ultrasonic methods allowed partition of body weight into fat, fat-free mass, skeletal muscle, and volume of heart, liver, kidneys, spleen, and tumor. These methods were used to evaluate body composition longitudinally in a pilot group of nine cancer p...

journal_title：Cancer

authors： Heymsfield SB,McManus CB

更新日期：1985-01-01 00:00:00

abstract：BACKGROUND:National Cancer Institute of Canada Clinical Trials Group PA.3 (NCIC CTG PA.3) was a phase 3 study (n = 569) that demonstrated benefits for overall survival and progression-free survival with the addition of the epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) erlotinib to gemcitabine ...

journal_title：Cancer

authors： da Cunha Santos G,Dhani N,Tu D,Chin K,Ludkovski O,Kamel-Reid S,Squire J,Parulekar W,Moore MJ,Tsao MS

更新日期：2010-12-15 00:00:00

abstract：BACKGROUND:Hospital services are expectantly reduced over the weekend, which may result in a delay in treatment or in obtainment of medical procedures. The authors investigated quality of care and clinical outcomes of newly diagnosed acute myeloid leukemia (AML) patients who were hospitalized on weekends versus weekday...

journal_title：Cancer

authors： Bejanyan N,Fu AZ,Lazaryan A,Fu R,Kalaycio M,Advani A,Sobecks R,Copelan E,Maciejewski JP,Sekeres MA

更新日期：2010-08-01 00:00:00

abstract：BACKGROUND:Uveal melanomas of the choroid and ciliary body are aggressive tumors causing the death of approximately 50% of patients. In contrast, iris melanomas only infrequently metastasize; why these differences exist is not known. The local environment can regulate cancer growth and development, and it is probable t...

journal_title：Cancer

authors： Canovas D,Rennie IG,Nichols CE,Sisley K

更新日期：2008-04-15 00:00:00

abstract：:Four courses of ifosfamide with mesna given by intravenous infusions were combined with bolus doxorubicin in a phase II trial to treat patients with breast cancer. Ifosfamide can deplete intracellular glutathione levels and because doxorubicin resistance may be associated with elevated levels of intracellular glutathi...

journal_title：Cancer

authors： Millward MJ,Harris AL,Cantwell BM

更新日期：1990-06-01 00:00:00

abstract：:Lymphoid cells from two patients with hand-mirror variant of acute lymphoblastic leukemia (ALL) were studied with various monoclonal antibodies in attempts to determine their derivation and differentiation. The predominant feature of the malignant bone marrow cells was strong reactivity with antibody 3A1, which stains...

journal_title：Cancer

authors： Gramatzki M,Strong DM,Duval-Arnould B,Morstyn G,Schumacher HR

更新日期：1985-01-01 00:00:00

abstract：BACKGROUND:Clinical trials established the value of breast-conserving treatment (BCT) including the macroscopic removal of the tumor followed by local radiation therapy (RT) for Stage I and II invasive carcinomas. The occurrence of local tumor recurrence is related to the extent and multifocality of the tumor. Various ...

journal_title：Cancer

authors： Faverly DR,Hendriks JH,Holland R

更新日期：2001-02-15 00:00:00

abstract：:Fifty-nine colorectal carcinomas of patients with verified cancer family syndrome (CFS) were analyzed for DNA ploidy using flow cytometry. Sixty-eight percent of the tumors were diploid, and 32% were aneuploid. The aneuploid tumors had a median DNA index of 1.24 (range, 1.12-1.97). In 90% of all tumors the DNA index w...

journal_title：Cancer

authors： Kouri M,Laasonen A,Mecklin JP,Järvinen H,Franssila K,Pyrhönen S

更新日期：1990-04-15 00:00:00

abstract：:Fourteen examples of intravenous leiomyomatosis in the FIP files were studied. Growth beyond the uterus occurred in 10 of the 14 examples, largely in vessels in the broad ligament and in uterine and iliac veins. Metastasis to the heart occurred in 1 example. The study provides evidence that is consistent with both the...

journal_title：Cancer

authors： Norris HJ,Parmley T

更新日期：1975-12-01 00:00:00

abstract：BACKGROUND:Methotrexate is a chemotherapeutic agent frequently utilized for the treatment of malignant, rheumatic, and pulmonary diseases. Although this agent has been extensively used for more than 45 years, there are few reports of immediate systemic hypersensitivity reactions. The reported immediate reactions includ...

journal_title：Cancer

authors： Alkins SA,Byrd JC,Morgan SK,Ward FT,Weiss RB

更新日期：1996-05-15 00:00:00

abstract：:The authors report a case of leiomyosarcoma in the mediastinum presenting with superior vena cava obstruction, and also demonstrate the aggressive nature of this tumor in spite of radiotherapy. Where technically feasible, surgery appears to be the treatment of choice. The pathologic and electron microscopic features o...

journal_title：Cancer

authors： Sunderrajan EV,Luger AM,Rosenholtz MJ,Maltby JD

更新日期：1984-06-01 00:00:00

abstract：BACKGROUND:The current study was conducted to evaluate the maximum tolerable dose of weekly gemcitabine administered simultaneously with radiation and cisplatin in patients with locally advanced nonsmall cell lung cancer (NSCLC). METHODS:Patients with stage IIIA/B NSCLC received concurrently 63 grays radiation and 20 ...

journal_title：Cancer

authors： Momm F,Kaden M,Tannock I,Schumacher M,Hasse J,Henke M

更新日期：2010-10-15 00:00:00

abstract：:The prognostic significance of ploidy level was studied in prostatic carcinoma and compared with the prognostic significance of morphologic grade and clinical stage. A nonselected group of 145 patients was studied in whom prostatic carcinoma was diagnosed by fine-needle aspiration biopsy at the Karolinska Hospital in ...

journal_title：Cancer

authors： Forsslund G,Esposti PL,Nilsson B,Zetterberg A

更新日期：1992-03-15 00:00:00

abstract：:Although Kaposi's sarcoma (KS) usually appears with solitary skin lesions, in a large percentage of these patients the disease progresses eventually to involve large extensive segments of the skin. In the past, the most frequently used approach is the irradiation of isolated lesions as they arose, hence the so-called ...

journal_title：Cancer

authors： Nisce LZ,Safai B,Poussin-Rosillo H

更新日期：1981-02-15 00:00:00

abstract：BACKGROUND:The median survival for patients with glioblastoma is reported to be 12 months. To improve the outcome for glioblastoma patients, the authors evaluated the therapeutic efficacy of preirradiation gemcitabine chemotherapy followed by standard radiotherapy. METHODS:Twenty-one patients with newly diagnosed glio...

journal_title：Cancer

authors： Weller M,Streffer J,Wick W,Kortmann RD,Heiss E,Küker W,Meyermann R,Dichgans J,Bamberg M

更新日期：2001-01-15 00:00:00

abstract：:A low-dose maintenance schedule of Adriamycin was evaluated in six children whose metastatic solid tumors regressed following toxic induction therapy with Adriamycin. Three of these children are now disease-free more than one year following discontinuation of therapy. Adriamycin can be given on a low-dose maintenance ...

journal_title：Cancer

authors： Hvizdala EV,Komp DM,Arnold JB

更新日期：1977-06-01 00:00:00

abstract：BACKGROUND:There is no standard therapy for surgery- and radiotherapy-resistant, recurrent, low-grade spinal cord gliomas. Therefore, a retrospective study of temozolomide (TMZ) in adults with recurrent low-grade spinal cord gliomas with a primary objective of determining progression-free survival (PFS) was performed. ...

journal_title：Cancer

authors： Chamberlain MC

更新日期：2008-09-01 00:00:00

abstract：BACKGROUND:Insulin receptor (IR), a member of the receptor tyrosine kinase family, is expressed in normal thyroid cells and affects thyroid cell proliferation and differentiation. METHODS:The authors measured IR content in benign and malignant thyroid tumors by three independent methods: a specific radioimmunoassay, 1...

journal_title：Cancer

authors： Frittitta L,Sciacca L,Catalfamo R,Ippolito A,Gangemi P,Pezzino V,Filetti S,Vigneri R

更新日期：1999-01-15 00:00:00

abstract：:We assessed the frequency of silent (i.e., clinically asymptomatic) cirrhosis among 305 patients with hepatocellular carcinoma (HCC) and cirrhosis in relation to the patients' country of birth, the cause of the cirrhosis, clinical features, and hepatitis B surface antigen (HBsAg) status. Overall, 56% of the patients h...

journal_title：Cancer

authors： Zaman SN,Johnson PJ,Williams R

更新日期：1990-04-01 00:00:00

abstract：BACKGROUND:Squamous cell lung carcinoma (SLC), the most frequent type of lung cancer, generally is treated surgically and its prognosis is poor. The only current clinically useful prognostic criterion is lymph node staging (TNM classification). Expression of a novel tumor-associated carbohydrate epitope Gal beta 1-3[Fu...

journal_title：Cancer

authors： Battifora H,Sorensen HR,Mehta P,Ahn C,Niland J,Hage E,Pettijohn DE,Olsson L

更新日期：1992-10-01 00:00:00

abstract：:Numerous examples exist of prognostic factors that have been conclusively established and that can segregate the target patient population into subgroups with vastly different outcomes. At the same time, we can expect, in the majority of trials being conducted, that if a new treatment turns out to be successful, it ge...

journal_title：Cancer

authors： Sather HN

更新日期：1986-07-15 00:00:00