Somatostatinoma of the cystic duct.

Abstract:

:An unusual tumor of the cystic duct in a 28-year-old woman is described. The patient presented with a painful distended gallbladder due to a small tumor occluding the cystic duct. Microscopically the tumor cells showed a nesting pattern suggestive of endocrine differentiation, but contained numerous lipid vacuoles and were argentaffin and argyrophil negative. Ultrastructurally, there were relatively few dense granules measuring 135 to 475 nm. Immunoperoxidase staining showed that the tumor cells contained somatostatin but did not contain immunoreactive ACTH, gastrin, calcitonin, glucagon, insulin, parathyroid hormone, or carcinoembryonic antigen. To the authors' knowledge, this is the first reported somatostatinoma occurring in the extrahepatic biliary tract.

journal_name

Cancer

journal_title

Cancer

authors

Goodman ZD,Albores-Saavedra J,Lundblad DM

doi

10.1002/1097-0142(19840201)53:3<498::aid-cncr28205

subject

Has Abstract

pub_date

1984-02-01 00:00:00

pages

498-502

issue

3

eissn

0008-543X

issn

1097-0142

journal_volume

53

pub_type

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