A controlled trial of extended radical versus radical mastectomy. Ten-year results.

abstract：:Results from the standpoint of survival rates and locoregional failures are compared in three series of patients having had a radical mastectomy for breast cancer: (1) radical mastectomy alone for the patients who had essentially outer quadrant lesions and a negative axilla; (2) postoperative irradiation when the axil...

journal_title：Cancer

authors： Rodger A,Montague ED,Fletcher G

更新日期：1983-04-15 00:00:00

abstract：BACKGROUND:The purpose of this study was to evaluate the results of thyroid fine-needle aspiration (FNA) and to determine the reasons for the discrepancies between the cytologic and histologic diagnoses. METHODS:The authors evaluated the cytologic and histologic results of 133 FNAs obtained from 92 patients who underw...

journal_title：Cancer

authors： Sidawy MK,Del Vecchio DM,Knoll SM

更新日期：1997-08-25 00:00:00

abstract：BACKGROUND:Medulloblastomas are small cell embryonal tumors of the cerebellum found predominantly in children, only slightly more than half of whom survive. Predicting favorable outcome has been difficult, and improved stratification clearly is required to avoid both undertreatment and overtreatment. Patients currently...

journal_title：Cancer

authors： Eberhart CG,Kepner JL,Goldthwaite PT,Kun LE,Duffner PK,Friedman HS,Strother DR,Burger PC

更新日期：2002-01-15 00:00:00

abstract：:A case of basosquamous or so-called transitional cloacogenic carcinoma of the sigmoid colon, which arose above the pelvic brim at the peritoneal reflection, is reported. We were not able to find a report of this histologic type of tumor arising this far from the pectinate line of the anus, which is the most common pri...

journal_title：Cancer

authors： Strate RW,Richardson JD,Bannayan GA

更新日期：1977-09-01 00:00:00

abstract：:The Southwest Oncology Group in a prospective randomized study compared one year of adjuvant combination chemotherapy with continuous CMFVP to two years of intermittent L-PAM in women with operable breast cancer with histologically positive axillary lymph nodes. In fully evaluable patients with a 42-month median and 3...

journal_title：Cancer

authors： Glucksberg H,Rivkin SE,Rasmussen S,Tranum B,Gad-el-Mawla N,Costanzi J,Hoogstraten B,Athens J,Maloney T,McCracken J,Vaughn C

更新日期：1982-08-01 00:00:00

abstract：BACKGROUND:In the United States, incidence rates for malignant tumors of the uterine corpus are lower among blacks than among whites, whereas mortality rates are higher among blacks. Reasons for the higher level of mortality among blacks have been debated. METHODS:Using data from the Surveillance, Epidemiology, and En...

journal_title：Cancer

authors： Sherman ME,Devesa SS

更新日期：2003-07-01 00:00:00

abstract：BACKGROUND:Despite published reports regarding the association of elevated circulating CD44 and CD54 levels with unfavorable outcome in non-Hodgkin lymphoma (NHL) and chronic lymphocytic leukemia (CLL), little is known about therapy-related changes in either adhesion molecule. In an attempt to evaluate the effect of in...

journal_title：Cancer

authors： Beksaç M,Arat M,Akan H,Koç H,Ilhan O,Ozcan M

更新日期：2000-10-01 00:00:00

abstract：:In 25 patients under treatment or during follow-up for acute lymphoblastic leukemia magnetic resonance imaging (MRI) of both knees was compared to history and physical examination to detect osteonecrosis. Results of MRI were classified as: O, normal bone marrow (BM); 1, diffuse decrease in signal intensity; 2, circums...

journal_title：Cancer

authors： Pieters R,van Brenk AI,Veerman AJ,van Amerongen AH,van Zanten TE,Golding RP

更新日期：1987-12-15 00:00:00

abstract：:A 22-micron glass microsphere called TheraSphere (Theragenics Corp., Atlanta, GA) has been developed in which yttrium 89 oxide is incorporated into the glass matrix and is activated by neutron bombardment to form the beta-emitting isotope yttrium 90 (Y 90) before using the spheres as radiotherapeutic vehicles. The inj...

journal_title：Cancer

authors： Wollner I,Knutsen C,Smith P,Prieskorn D,Chrisp C,Andrews J,Juni J,Warber S,Klevering J,Crudup J

更新日期：1988-04-01 00:00:00

abstract：BACKGROUND:A rigorous assessment of the risk of colorectal cancer (CRC) among prostate cancer (PC) survivors that controls for important confounding factors and competing risks is necessary to determine the risk of CRC in this population and to inform screening guidelines. METHODS:With data from Manitoba, Canada, subj...

journal_title：Cancer

authors： Desautels D,Czaykowski P,Nugent Z,Demers AA,Mahmud SM,Singh H

更新日期：2016-04-15 00:00:00

abstract：:Between September 1976 and May 1980, 135 patients with operable breast cancer and positive axillary nodes received l-phenylalanine mustard, adjunct to surgery, 0.15 mg/kg for five days, six weekly, and were randomised prospectively to levamisole 150 mg for three days, two weekly, or a placebo. Treatment was continued ...

journal_title：Cancer

authors： Kay RG,Mason BH,Stephens EJ,Arthur JF,Hitchcock GC,Trindall PL,Rodgers R,Mullins P

更新日期：1983-06-01 00:00:00

abstract：BACKGROUND:American Indians/Alaskan Natives (AI/ANs) have the worst 5-year cancer survival of all racial/ethnic groups in the United States. Causes for this disparity are unknown. The authors of this report examined the receipt of cancer treatment among AI/AN patients compared with white patients. METHODS:This was a r...

journal_title：Cancer

authors： Javid SH,Varghese TK,Morris AM,Porter MP,He H,Buchwald D,Flum DR,Collaborative to Improve Native Cancer Outcomes (CINCO).

更新日期：2014-07-15 00:00:00

abstract：:The use of preoperative computed tomographic (CT) scans of the chest in carcinoma of the esophagus to associate preoperative staging with postoperative survival is controversial. Thirty-two patients who underwent esophagectomy and reconstruction were examined with respect to a variety of variables available on preoper...

journal_title：Cancer

authors： Lefor AT,Merino MM,Steinberg SM,Dwyer A,Roth JA,Flanagan M,Pass HI

更新日期：1988-10-01 00:00:00

abstract：BACKGROUND:Combined transperineal prostate brachytherapy and external beam radiation therapy (EBRT) is widely used for treatment of prostate cancer. Long-term efficacy and toxicity results of a multicenter phase 2 trial assessing combination of EBRT and transperineal prostate brachytherapy boost with androgen deprivati...

journal_title：Cancer

authors： Hurwitz MD,Halabi S,Archer L,McGinnis LS,Kuettel MR,DiBiase SJ,Small EJ

更新日期：2011-12-15 00:00:00

abstract：:A case of pancreatoblastoma, arising in the tail of the pancreas with metastases to the right radius, in an 8-year-old boy is reported. The serum alpha-fetoprotein (AFP) level was over 13 times the normal value before surgery, but returned to normal after removal of the primary tumor. Furthermore, AFP was detected in ...

journal_title：Cancer

authors： Iseki M,Suzuki T,Koizumi Y,Hirose M,Laskin WB,Nakazawa S,Ohaki Y

更新日期：1986-05-01 00:00:00

abstract：BACKGROUND:hMLH1, the human MutL homologue, has been linked to microsatellite instability (MSI) in gastrointestinal tumors. However, to the authors' knowledge, the role of hMLH1, the other mismatch repair genes (MMR), and MSI in ovarian carcinoma has not been well defined. The purpose of the current study was to determ...

journal_title：Cancer

authors： Geisler JP,Goodheart MJ,Sood AK,Holmes RJ,Hatterman-Zogg MA,Buller RE

更新日期：2003-11-15 00:00:00

abstract：BACKGROUND:Anemia in patients receiving chemotherapy can be ameliorated with recombinant human erythropoietin (rHuEPO), which is administered one to three times per week. Darbepoetin alpha, a new erythropoietic agent, has longer serum residence time, allowing it to be administered less frequently. METHODS:Patients (n ...

journal_title：Cancer

authors： Glaspy JA,Jadeja JS,Justice G,Fleishman A,Rossi G,Colowick AB

更新日期：2003-03-01 00:00:00

abstract：BACKGROUND:Results from numerous trials have indicated that breast-conserving therapy (BCT) produces outcomes equivalent to those produced by mastectomy in terms of both locoregional control and survival. However, conservative treatment has resulted in the dilemma of how best to address recurrences when they appear in ...

journal_title：Cancer

authors： Vicini FA,Antonucci JV,Goldstein N,Wallace M,Kestin L,Krauss D,Kunzmann J,Gilbert S,Schell S

更新日期：2007-04-01 00:00:00

abstract：:A novel sequential administration schedule of PALA (N-phosphonoacetyl-L-aspartate) and thymidine to enhance the cytotoxic effect of 5-fluorouracil (5FU) was tested in 36 patients with advanced gastric cancer and 21 patients with advanced poorly differentiated (anaplastic) colorectal cancer. The potency of 5FU was dram...

journal_title：Cancer

authors： Windschitl HE,O'Connell MJ,Wieand HS,Krook JE,Rubin J,Moertel CG,Kugler JW,Pfeifle DM,Goldberg RM,Laurie JA

更新日期：1990-09-01 00:00:00

abstract：:Estradiol and testosterone levels in the peripheral and ovarian circulation of patients with endometrial cancer and of postmenopausal women were studied. These levels proved to be the same in the two groups. The ovaries of neither group secreted estradiol. The testosterone level in the ovarian circulation of all exami...

journal_title：Cancer

authors： Schenker JG,Weinstein D,Okon E

更新日期：1979-11-01 00:00:00

abstract：BACKGROUND:Patients scheduled to receive chemotherapy frequently undergo pretherapy dental treatment to eliminate potential sources of odontogenic infection. A prospective study was conducted to assess a new protocol emphasizing minimal pretherapy dental treatment. METHODS:Forty-eight consecutive patients diagnosed wi...

journal_title：Cancer

authors： Toljanic JA,Bedard JF,Larson RA,Fox JP

更新日期：1999-04-15 00:00:00

abstract：:Methionine-depleting total parenteral nutrition (methionine-depleting TPN), which infuses an amino acid solution devoid of L-methionine and L-cysteine as the sole protein source, showed enhancement of the effect of several anti-cancer agents. In this study, the combined effect of the methionine-depleting TPN with the ...

journal_title：Cancer

authors： Goseki N,Yamazaki S,Endo M,Onodera T,Kosaki G,Hibino Y,Kuwahata T

更新日期：1992-04-01 00:00:00

abstract：BACKGROUND:Several of the large studies addressing prognosis and survival from hepatocellular carcinoma (HCC) have been from Europe and Asia, but only a few have emanated from North America. Survival statistics from other parts of the world may not be applicable to the North American population because of etiologic, de...

journal_title：Cancer

authors： Nzeako UC,Goodman ZD,Ishak KG

更新日期：1995-08-15 00:00:00

abstract：BACKGROUND:Pretreatment serum prostate specific antigen (PSA) level is a powerful prognostic factor for clinically localized prostate carcinoma. The traditional prognostic factors, T classification and Gleason score, appear to have been relegated to a minor position. This study was conducted to evaluate the relative pr...

journal_title：Cancer

authors： Zagars GK,Pollack A,von Eschenbach AC

更新日期：1997-04-01 00:00:00

abstract：BACKGROUND:Gastric carcinoma is one of the most common malignancies worldwide, with an overall survival of about 10%. Improvement in therapy awaits better understanding of the biologic behavior of this tumor. Establishment of cell lines permits detailed analysis of the biology of gastric cancer. The authors report on t...

journal_title：Cancer

authors： Altorki N,Schwartz GK,Blundell M,Davis BM,Kelsen DP,Albino AP

更新日期：1993-08-01 00:00:00

abstract：:In a retrospective analysis of 166 patients with chronic hepatitis B followed for up to 8 years, 22 patients had 29 episodes of elevations in serum alpha-fetoprotein (AFP) levels. Twenty-five episodes were due to a transient exacerbation of the underlying hepatitis and 11 of these episodes were followed by a loss of h...

journal_title：Cancer

authors： Di Bisceglie AM,Hoofnagle JH

更新日期：1989-11-15 00:00:00

abstract：BACKGROUND:Although several refinements have been reported for breast magnetic resonance imaging (MRI), there has been no uniform agreement by researchers on the optimal method. The authors report a simple and effective MRI method that incorporated the best qualities of other breast MRI methods yet eliminated the compl...

journal_title：Cancer

authors： Khatri VP,Stuppino JJ,Espinosa MH,Pollack MS

更新日期：2001-08-01 00:00:00

abstract：BACKGROUND:It has been suggested that tissue factor (TF) plays an important role in tumor metastasis. Its expression in sarcoma cells was reported to up-regulate the vascular endothelial growth factor (VEGF) gene and thereby enhance tumor angiogenesis, which is essential to tumor metastasis. Although many malignant tum...

journal_title：Cancer

authors： Seto S,Onodera H,Kaido T,Yoshikawa A,Ishigami S,Arii S,Imamura M

更新日期：2000-01-15 00:00:00

abstract：:The authors present a retrospective review of 90 cases of Stage III endometrial carcinoma seen over a 10-year period at the Princess Margaret Hospital, Toronto. Overall 5-year survival was 45.5% and disease-free survival was 36.0%. Prognostic factors identified within Stage III were tumor grade, geographic distributio...

journal_title：Cancer

authors： Mackillop WJ,Pringle JF

更新日期：1985-11-15 00:00:00

abstract：:Seventy-six patients with malignant germ cell tumors of the ovary received vincristine, dactinomycin, and cyclophosphamide (VAC) postoperatively. Fifty-four were treated after removal of all gross disease. The majority of these remain disease-free. Indeed, only 15 (28%) have failed, including 11 of 24 with pure endode...

journal_title：Cancer

authors： Slayton RE,Park RC,Silverberg SG,Shingleton H,Creasman WT,Blessing JA

更新日期：1985-07-15 00:00:00