Mismatch repair gene expression defects contribute to microsatellite instability in ovarian carcinoma.

abstract：:The study is a clinicopathologic report on 64 patients with primary adenocarcinoma of the urinary bladder and urachus, with particular reference to important prognostic and therapeutic factors. All tumors exhibited adenocarcinomatous features in at least two thirds of the examined tumor area. Pure forms of the differe...

journal_title：Cancer

authors： Anderström C,Johansson SL,von Schultz L

更新日期：1983-10-01 00:00:00

abstract：BACKGROUND:Fear of cancer recurrence (FCR) adversely affects quality of life. Cigarette smoking increases the risk of recurrence and may exacerbate FCR among survivors who smoke. FCR also may motivate quitting, but research on whether quitting reduces long-term survivors' FCR is lacking. Among long-term survivors of va...

journal_title：Cancer

authors： Westmaas JL,Thewes B,Séguin Leclair C,Lebel S

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:Although acquired somatic mutations presumably are crucial in carcinogenesis, nothing is known about the chromosome aberrations of bilateral breast carcinomas. METHODS:Eighteen specimens from 16 bilateral carcinomas were analyzed cytogenetically. The banding analysis was supplemented with fluorescence in si...

journal_title：Cancer

authors： Pandis N,Teixeira MR,Gerdes AM,Limon J,Bardi G,Andersen JA,Idvall I,Mandahl N,Mitelman F,Heim S

更新日期：1995-07-15 00:00:00

abstract：:Histologic examination of bone-marrow from the posterior iliac crest was routinely done as a pretreatment staging procedure in 203 consecutive patients with small-cell anaplastic carcinoma of the lung. Subtyping of the patients according to the WHO classification included 27.8% with "fusiform" cell type (WHO II,1), 28...

journal_title：Cancer

authors： Hirsch F,Hansen HH,Dombernowsky P,Hainau B

更新日期：1977-06-01 00:00:00

abstract：:Thirty-one patients were treated with cisplatin combination chemotherapy for advanced seminoma (26 Stage III or bulky Stage II testicular, and five disseminated extragonadal). Seventeen (89%) of 19 patients not previously pretreated and four (80%) of five who had received only abdominal irradiation entered continuous ...

journal_title：Cancer

authors： Pizzocaro G,Salvioni R,Piva L,Zanoni F,Milani A,Faustini M

更新日期：1986-10-15 00:00:00

abstract：:The immunologic and clinicopathologic features of common acute lymphoblastic leukemia antigen (CALLA)-positive and CALLA-negative T-acute lymphoblastic leukemia (ALL) and of CALLA-positive non-T, non-B ALL (common ALL) of childhood were compared. Twenty-seven percent of children with T-ALL had blasts that expressed CA...

journal_title：Cancer

authors： Dowell BL,Borowitz MJ,Boyett JM,Pullen DJ,Crist WM,Quddus FF,Russell EC,Falletta JM,Metzgar RS

更新日期：1987-06-15 00:00:00

abstract：:The majority of patients with advanced ovarian cancer progress after first-line therapy and require further treatment. Tumor biology, prior chemotherapy, responses to previous therapy, performance status, and toxicity are the characteristics that influence treatment choice. These criteria have been linked to the time ...

journal_title：Cancer

authors： Pignata S,Pisano C,Di Napoli M,Cecere SC,Tambaro R,Attademo L

更新日期：2019-12-15 00:00:00

abstract：:Lymphoblasts from "null cell" acute lymphocytic leukemia (ALL) were analyzed for the pattern of proliferation displayed in a mixed lymphocyte reaction (MLR), the presence of a B cell surface antigen, and for the presence of intracytoplasmic immunoglobulin (ICIg). "Null cell" ALL was defined by cytologic and cytochemic...

journal_title：Cancer

authors： Davey FR,Dock NL,Wolos JA,Terzian JA,Gottlieb AJ

更新日期：1979-11-01 00:00:00

abstract：:Since 1975, clinical studies have been carried out to determine whether radiation when combined with localized hyperthermia evokes improved tumor control compared to that achieved with radiation alone. Local tumor hyperthermia was achieved using radiofrequency inductive heating at 27.12 MHz. In bulky lesions (greater ...

journal_title：Cancer

authors： Kim JH,Hahn EW,Ahmed SA

更新日期：1982-08-01 00:00:00

abstract：:Greatest surface diameter of a cancer, together with suspicion of regional node metastasis, forms the basis for prognosis through the clinical TNM staging system for many cancers. In oral cancer, however, surface size sometimes fails to correlate, or sometimes inversely correlates, with tumor aggressiveness. To shed l...

journal_title：Cancer

authors： Moore C,Flynn MB,Greenberg RA

更新日期：1986-07-01 00:00:00

abstract：BACKGROUND:Podoplanin is a mucin-like glycoprotein that is important in lymphangiogenesis but not blood vessel formation. Recent studies suggested a potential role of podoplanin in certain tumor cells. The purpose of the current study was to determine the role of podoplanin in head and neck squamous cell carcinoma (HNS...

journal_title：Cancer

authors： Yuan P,Temam S,El-Naggar A,Zhou X,Liu DD,Lee JJ,Mao L

更新日期：2006-08-01 00:00:00

abstract：BACKGROUND:Preclinical and clinical studies suggest synergistic activity between somatostatin analogues and mammalian target of rapamycin inhibitors. The activity and safety of everolimus was assessed in combination with octreotide long-acting repeatable (LAR) in patients with neuroendocrine tumors (NETs) of gastroente...

journal_title：Cancer

authors： Bajetta E,Catena L,Fazio N,Pusceddu S,Biondani P,Blanco G,Ricci S,Aieta M,Pucci F,Valente M,Bianco N,Mauri CM,Spada F

更新日期：2014-08-15 00:00:00

abstract：:Seventy patients with poor prognosis, metastatic breast cancer were treated with FUVAC induction chemotherapy (5-fluorouracil, vinblastine, Adriamycin [doxorubicin] and cyclophosphamide). Consolidation therapy was given to 30 of 48 responders (63%), of whom 23 received sequential hemibody irradiation (HBI) at 8 cGy, c...

journal_title：Cancer

authors： Livingston RB,Schulman S,Griffin BR,Tranum BL,Rivkin SE,Goldberg RS,Fabian CJ,Hammond N,Hynes H

更新日期：1987-04-01 00:00:00

abstract：BACKGROUND:Fine-needle aspiration biopsy (FNA) has been successful in diagnosing epithelial lesions of the breast. Its role in the evaluation of spindle cell and mesenchymal lesions of the breast, which include a variety of benign and malignant conditions, is less clear. This article discusses the cytologic features an...

journal_title：Cancer

authors： Chhieng DC,Cangiarella JF,Waisman J,Fernandez G,Cohen JM

更新日期：1999-12-25 00:00:00

abstract：:The changes in skeletal muscle mass of 14 children with newly diagnosed acute leukemia were studied during the first 24 weeks of antileukemia therapy. A muscle index was calculated from the femoral quadriceps muscle thickness, measured by using an ultrasound method, and from the body surface area. Serum albumin concen...

journal_title：Cancer

authors： Koskelo EK,Saarinen UM,Siimes MA

更新日期：1990-07-15 00:00:00

abstract：BACKGROUND:The human papillomavirus (HPV) E2 protein is a transcriptional repressor of the oncogenes E6/E7 and loss of E2 function is considered a key step in carcinogenesis. Integration of HPV into the host genome may disrupt the E2 gene. Furthermore, methylation of CpG dinucleotides in E2-binding sites (E2BSs) in the...

journal_title：Cancer

authors： Reuschenbach M,Huebbers CU,Prigge ES,Bermejo JL,Kalteis MS,Preuss SF,Seuthe IM,Kolligs J,Speel EJ,Olthof N,Kremer B,Wagner S,Klussmann JP,Vinokurova S,von Knebel Doeberitz M

更新日期：2015-06-15 00:00:00

abstract：BACKGROUND:Capecitabine with oxaliplatin (CAPOX) has previously demonstrated clinical activity in patients with small bowel adenocarcinoma (SBA) and ampullary adenocarcinoma (AAC). Herein, the authors conducted a phase 2 trial to evaluate the benefit of adding bevacizumab to CAPOX. METHODS:In this phase 2, single-arm,...

journal_title：Cancer

authors： Gulhati P,Raghav K,Shroff RT,Varadhachary GR,Kopetz S,Javle M,Qiao W,Wang H,Morris J,Wolff RA,Overman MJ

更新日期：2017-05-15 00:00:00

abstract：:Increased in vitro tetraploidy occurred in skin cultures derived from all affected patients and some family members at risk studied in families with heritable colon cancer syndromes (15 of 16 Gardner syndrome families, three Oldfield syndrome families, and four families with heritable colon cancer syndrome without pol...

journal_title：Cancer

authors： Danes BS

更新日期：1981-10-01 00:00:00

abstract：:The concept that most transitional cell neoplasms of the urinary bladder exist as either nonaggressive lesions of low cytologic grade or aggressive anaplastic cancers is gradually gaining acceptance. The extent to which the biological potential of these neoplasms is revealed in their pathologic features is the subject...

journal_title：Cancer

authors： Jordan AM,Weingarten J,Murphy WM

更新日期：1987-12-01 00:00:00

abstract：BACKGROUND:Previous Commission on Cancer studies have examined time trends in stage of disease, treatment patterns, and survival for special populations. Reported herein are the most current National Cancer Data Base data for Hispanics. METHODS:Two Calls for Data have yielded a total of 23,650 cancer reports for Hispa...

journal_title：Cancer

authors： Villar HV,Menck HR

更新日期：1994-10-15 00:00:00

abstract：BACKGROUND:Since the 1970s, incidence rates of esophageal and gastric cardia adenocarcinoma have risen substantially. Reasons for the increasing trends are not well understood. METHODS:A population-based, case-control study that included esophageal adenocarcinomas (n = 222), gastric cardia adenocarcinomas (n = 277), d...

journal_title：Cancer

authors： Wu AH,Tseng CC,Bernstein L

更新日期：2003-09-01 00:00:00

abstract：:Three-hundred whole thyroid glands were collected at autopsy from patients who had no known clinical history of thyroid disease, and who varied from 13 to 82 years of age; 200 were male and 100 female. Thyroid glands were weighed, measured, and examined after previous formalin fixation. Histologic examination was done...

journal_title：Cancer

authors： Bisi H,Fernandes VS,de Camargo RY,Koch L,Abdo AH,de Brito T

更新日期：1989-11-01 00:00:00

abstract：:From November 1985 to August 1988, the National Study Group for Oesophageal Cancer collected and centralized data on 1926 new cases of oesophageal cancer in South Africa. A standard data sheet was used to record the age, sex, and condition of the patients, the site, length, and circumferential extent of the tumor, the...

journal_title：Cancer

authors： Mannell A,Murray W

更新日期：1989-12-15 00:00:00

abstract：BACKGROUND:The health-related functioning of patients with cancer is compromised by several factors, including the disease process, treatment, and the various symptoms that are produced by both disease and treatment. This study was designed to specify the relationship between patients' pain severity and their self-repo...

journal_title：Cancer

authors： Wang XS,Cleeland CS,Mendoza TR,Engstrom MC,Liu S,Xu G,Hao X,Wang Y,Ren XS

更新日期：1999-11-01 00:00:00

abstract：BACKGROUND:Adenocarcinomas of the appendix represent a heterogeneous disease depending on the presence of mucinous histology, histologic grade, and stage. In the current study, the authors sought to explore the interplay of these factors with systemic chemotherapy in a large population data set. METHODS:Patients in th...

journal_title：Cancer

authors： Asare EA,Compton CC,Hanna NN,Kosinski LA,Washington MK,Kakar S,Weiser MR,Overman MJ

更新日期：2016-01-15 00:00:00

abstract：BACKGROUND:Nipple duct lavage (NDL) may be useful for breast cancer risk stratification. Published guidelines recommend that women with a 5-year Gail risk >/=1.7% should consider undergoing lavage for any fluid-yielding ducts, but it is not known whether increased breast cancer risk or nipple fluid production predict l...

journal_title：Cancer

authors： Bushnaq ZI,Ashfaq R,Leitch AM,Euhus D

更新日期：2007-04-01 00:00:00

abstract：:Over the last decade, new cytotoxic treatments and targeted therapies have altered treatment paradigms for patients with metastatic non-small cell lung cancer (NSCLC). We sought to analyze the impact of histology and biomarker selection criteria on outcomes of clinical trials in metastatic NSCLC reported over the last...

journal_title：Cancer

authors： Gentzler RD,Yentz SE,Johnson ML,Rademaker AW,Patel JD

更新日期：2014-12-15 00:00:00

abstract：BACKGROUND:The objective of this study was to assess the value of combined-modality therapy in elderly patients by comparing the differences in outcome between patients who received radiotherapy (RT) alone and patients who received RT plus chemotherapy for stage III nonsmall cell lung cancer (NSCLC). METHODS:The North...

journal_title：Cancer

authors： Schild SE,Mandrekar SJ,Jatoi A,McGinnis WL,Stella PJ,Deming RL,Jett JR,Garces YI,Allen KL,Adjei AA,North Central Cancer Treatment GroupThis study was conducted as a collaborative trial of the North Central Cancer Treatment Group and

更新日期：2007-07-15 00:00:00

abstract：:The authors present a retrospective review of 90 cases of Stage III endometrial carcinoma seen over a 10-year period at the Princess Margaret Hospital, Toronto. Overall 5-year survival was 45.5% and disease-free survival was 36.0%. Prognostic factors identified within Stage III were tumor grade, geographic distributio...

journal_title：Cancer

authors： Mackillop WJ,Pringle JF

更新日期：1985-11-15 00:00:00

abstract：BACKGROUND:Clinical practice guidelines for the management of breast carcinoma were introduced in Australia in October, 1995. This article describes the management of early-stage breast carcinoma both before and after the introduction of these guidelines. METHODS:All cases of early breast carcinoma that were diagnosed...

journal_title：Cancer

authors： White V,Pruden M,Giles G,Collins J,Jamrozik K,Inglis G,Boyages J,Hill D

更新日期：2004-08-01 00:00:00