Occurrence of in vitro tetraploidy in the heritable colon cancer syndromes.

abstract：BACKGROUND:Because the prostatic capsule is often indistinct, recognition of extraprostatic extension by carcinoma depends heavily on the identification of carcinoma cells in the periprostatic adipose tissue. However, the distribution of adipose tissue along the prostatic surfaces has not been studied extensively. MET...

journal_title：Cancer

authors： Hong H,Koch MO,Foster RS,Bihrle R,Gardner TA,Fyffe J,Ulbright TM,Eble JN,Cheng L

更新日期：2003-04-01 00:00:00

abstract：BACKGROUND:The authors administered a combination of docetaxel and topotecan with granulocyte-colony-stimulating factor (G-CSF) support in a Phase I study to define the maximum tolerated dose (MTD) of this regimen. METHODS:Patients with advanced-stage solid tumors were eligible for this trial if they had a Zubrod perf...

journal_title：Cancer

authors： Tsao AS,Shin DM,Palmer JL,Lee JS,Glisson BS

更新日期：2004-05-15 00:00:00

abstract：:This presentation will focus on the issues of access to care, insurance, and personpower in pediatric oncology. The invitation to participate in this workshop was addressed to me as former Chairman of the Section of Hematology/Oncology of the American Academy of Pediatrics and current Chairman of the sub-board of Pedi...

journal_title：Cancer

authors： Gilchrist GS

更新日期：1993-05-15 00:00:00

abstract：BACKGROUND:Uveal melanomas of the choroid and ciliary body are aggressive tumors causing the death of approximately 50% of patients. In contrast, iris melanomas only infrequently metastasize; why these differences exist is not known. The local environment can regulate cancer growth and development, and it is probable t...

journal_title：Cancer

authors： Canovas D,Rennie IG,Nichols CE,Sisley K

更新日期：2008-04-15 00:00:00

abstract：:Ten consecutive diffuse histiocytic lymphoma (DHL) cell lines established in our laboratory were studied for the presence of Epstein-Barr virus (EBV) genomes, lysozyme, nonspecific esterase and other cytochemical reactions, phagocytic activity, cytoplasmic immunoglobulin light and heavy chains, and surface receptors t...

journal_title：Cancer

authors： Epstein AL,Levy R,Kim H,Henle W,Henle G,Kaplan HS

更新日期：1978-11-01 00:00:00

abstract：:The experience of 260 patients with endometrial carcinoma was reviewed. The influence of factors such as age, stage of disease, grade and degree of myometrial penetration on the survival was presented, showing that survival decreases in elderly patients, in patients with advanced stage of disease, when the tumor is un...

journal_title：Cancer

authors： Tavares MA,Patricio MB,Vilhena M,Da Silva JN

更新日期：1977-02-01 00:00:00

abstract：BACKGROUND:The ThinPrep Pap Test (TP), a liquid-based cervical cytology preparation, was approved for use in the U.S. in 1996. The purpose of this study was to compare TP performance and biopsy follow-up studies with a similar population of high risk patients sampled by conventional Papanicolaou (Pap) smear (CS). METH...

journal_title：Cancer

authors： Carpenter AB,Davey DD

更新日期：1999-06-25 00:00:00

abstract：:From February 1972 to July 1975, 200 lung cancer patients were seen at the University of Rochester Cancer Center's Division of Radiation Oncology; 40% had squamous cell tumors and 87.5% had advanced disease localized to the thorax. Of the 160 patients who completed treatment, 101 were treated with continuous therapy s...

journal_title：Cancer

authors： Salazar OM,Rubin P,Brown JC,Feldstein ML,Keller BE

更新日期：1976-06-01 00:00:00

abstract：BACKGROUND:BRCA2 gene, located at chromosome 13q12.3, frequently is altered in familial types of cancer in which a "double-hit" inactivation model seems to occur. In contrast, in sporadic forms of cancer there is frequent absence of a second event (point mutations) suggesting that allelic imbalance at the BRCA2 locus m...

journal_title：Cancer

authors： Gorgoulis VG,Kotsinas A,Zacharatos P,Mariatos G,Liloglou T,Tsoli E,Kokotas S,Fassoulas C,Field JK,Kittas C

更新日期：2000-11-01 00:00:00

abstract：:Two hundred-eighty patients were randomized to receive either BCNU, hydroxyurea and imidazole carboxamide (BHD), BHD plus levamisole, or high-dose DTIC plus actinomycin D. There was no difference in response rate in the three groups (24%, 25% and 22%). Females responded better than males and, as expected, those with a...

journal_title：Cancer

authors： Costanzi JJ,Fletcher WS,Balcerzak SP,Taylor S,Eyre HJ,O'Bryan RM,Al-Sarraf M,Frank J

更新日期：1984-02-15 00:00:00

abstract：BACKGROUND:An epidermal growth factor receptor (EGFR) immunohistochemical detection system currently is being developed. The current study attempts to address background EGFR reactivity issues before determining the optimum EGFR scoring system. METHODS:Tissue sections from 102 patients with T3N1-2M1 colon adenocarcino...

journal_title：Cancer

authors： Goldstein NS,Armin M

更新日期：2001-09-01 00:00:00

abstract：:Therapeutic intervention in a course of illness, while producing the desired result, also may have some adverse long-term effects on the patient. Second malignancies are one of the known complications of therapy. The treatments of gynecologic cancers by surgery, irradiation and chemotherapy have been associated with s...

journal_title：Cancer

authors： Messerschmidt GL,Hoover R,Young RC

更新日期：1981-07-15 00:00:00

abstract：BACKGROUND:Chronic disseminated candidiasis (CDC) is a serious complication of treatment in patients with acute leukemia. Although some general risk factors are known to predispose to systemic fungal infections, few studies have addressed the relevance of certain clinical and laboratory features in patients with CDC. ...

journal_title：Cancer

authors： Sallah S,Wan JY,Nguyen NP,Vos P,Sigounas G

更新日期：2001-09-15 00:00:00

abstract：:Recombinant human granulocyte colony-stimulating factor (rhG-CSF) was administered intraperitoneally in combination with multidrug chemotherapy using methotrexate (M), vinblastine (V), doxorubicin (A), and cisplatin (C, or for the combination, MVAC) to C3H/He mice (5-week-old females) after experimental carcinoma, MBT...

journal_title：Cancer

authors： Akaza H,Fukushima H,Koiso K,Aso Y

更新日期：1992-02-15 00:00:00

abstract：:In the evaluation of cervical cancer, computed tomography (CT) is used primarily to stage advanced tumors and evaluate for recurrence. Because of reports that CT imaging lacks sensitivity and specificity in the detection of primary tumors and metastatic lesions, its use in these applications has been limited, but rece...

journal_title：Cancer

authors： Pannu HK,Fishman EK

更新日期：2003-11-01 00:00:00

abstract：BACKGROUND:There is concern that antioxidant supplement use during chemotherapy and radiation therapy may decrease treatment effects, yet the effects of such supplements on recurrence and survival are largely unknown. METHODS:The authors prospectively examined the associations between antioxidant use after breast canc...

journal_title：Cancer

authors： Greenlee H,Kwan ML,Kushi LH,Song J,Castillo A,Weltzien E,Quesenberry CP Jr,Caan BJ

更新日期：2012-04-15 00:00:00

abstract：:The incidence of gastric cancer has declined markedly in Finland during the last 4 decades. To document the changes caused by that in the ratio of the intestinal type (IT) to the diffuse type (DT) of gastric carcinoma we compared the 367 cases diagnosed from southwestern Finland at the Department of Pathology, Turku U...

journal_title：Cancer

authors： Laurén PA,Nevalainen TJ

更新日期：1993-05-15 00:00:00

abstract：BACKGROUND:Minority patients with cancer are at risk for undertreatment of cancer-related pain. Most studies of patient-related barriers to pain control have surveyed primarily non-Hispanic Caucasian patients. The purpose of the current study was to explore barriers to optimal pain management among African-American and...

journal_title：Cancer

authors： Anderson KO,Richman SP,Hurley J,Palos G,Valero V,Mendoza TR,Gning I,Cleeland CS

更新日期：2002-04-15 00:00:00

abstract：:The colon and rectum were removed from 445 consecutive autopsies and examined for the presence of polypoid lesions under an illuminating magnifying lens. There were seven clinically undiagnosed carcinomas, 329 adenomas, 174 hyperplastic polyps, 59 mucosal tags, 34 other polypoid lesions, and 54 polyps in which no hist...

journal_title：Cancer

authors： Vatn MH,Stalsberg H

更新日期：1982-02-15 00:00:00

abstract：BACKGROUND:Chemotherapy improves survival for patients with stage III colon cancer, but some older patients with lymph node-positive colon cancer do not see a medical oncologist and, thus, do not receive adjuvant chemotherapy. METHODS:To evaluate the role of the surgeon in determining referrals to medical oncology amo...

journal_title：Cancer

authors： Luo R,Giordano SH,Zhang DD,Freeman J,Goodwin JS

更新日期：2007-03-01 00:00:00

abstract：:Between February 1980 and December 1985, splenectomies were performed in 13 patients with advanced (Stage III and IV) chronic lymphocytic leukemia (CLL). Patients had advanced disease for a median of 32 months at the time of splenectomy and all were refractory to chemotherapy. All patients were anemic with a median he...

journal_title：Cancer

authors： Stein RS,Weikert D,Reynolds V,Greer JP,Flexner JM

更新日期：1987-05-15 00:00:00

abstract：BACKGROUND:Aggressive angiomyxoma is an uncommon mesenchymal tumor that preferentially involves the pelvic and perineal regions of females. Since its initial description in 1983, approximately 65 cases have been reported in the English literature. METHODS:The clinical and pathologic features of 29 cases of aggressive ...

journal_title：Cancer

authors： Fetsch JF,Laskin WB,Lefkowitz M,Kindblom LG,Meis-Kindblom JM

更新日期：1996-07-01 00:00:00

abstract：:In view of increasing debate over possible benefit of more complete surgery compared to conservative procedures, a randomized controlled trial contrasting the then standard Halsted radical (RDL) operation with the more complete extended radical (EXT) mastectomy was initiated in 1973. Between November 1973 and July 198...

journal_title：Cancer

authors： Meier P,Ferguson DJ,Karrison T

更新日期：1989-01-01 00:00:00

abstract：BACKGROUND:Human papillomavirus (HPV) DNA has been identified in esophageal carcinomas. However, the incidence of HPV varies significantly in different geographic locations. In the current study, neoplasms from two separate geographic regions were analyzed for the presence of HPV DNA: METHODS:One hundred and ten esoph...

journal_title：Cancer

authors： Suzuk L,Noffsinger AE,Hui YZ,Fenoglio-Preiser CM

更新日期：1996-08-15 00:00:00

abstract：BACKGROUND:Men who receive androgen-deprivation therapy (ADT) for prostate cancer experience several side effects from this treatment. A few recent studies have examined the cognitive implications of ADT and how they impact a patient's treatment decision-making, occupational pursuits, and quality of life. For this repo...

journal_title：Cancer

authors： Nelson CJ,Lee JS,Gamboa MC,Roth AJ

更新日期：2008-09-01 00:00:00

abstract：:The authors studied the expression of c-myc and ras family oncogene products in 43 cases of malignant lymphoma (ML) using the immunoperoxidase method. Unfixed frozen sections of lymph nodes from four patients with Hodgkin's disease and 39 with non-Hodgkin's lymphoma, together with normal lymph nodes, were studied by t...

journal_title：Cancer

authors： Mitani S,Sugawara I,Shiku H,Mori S

更新日期：1988-11-15 00:00:00

abstract：BACKGROUND:A large amount of interindividual variability exists in the occurrence of symptoms in patients receiving chemotherapy (CTX). The purposes of the current study, which was performed in a sample of 582 oncology outpatients who were receiving CTX, were to identify subgroups of patients based on their distinct ex...

journal_title：Cancer

authors： Miaskowski C,Cooper BA,Melisko M,Chen LM,Mastick J,West C,Paul SM,Dunn LB,Schmidt BL,Hammer M,Cartwright F,Wright F,Langford DJ,Lee K,Aouizerat BE

更新日期：2014-08-01 00:00:00

abstract：:The authors retrospectively reviewed 50 episodes of spinal epidural tumor that occurred in 42 patients with metastatic prostate cancer and were treated with external-beam radiation. Treatment response was evaluated in terms of symptoms, neurologic status, and, in most cases, reduction of tumor on repeat myelography. A...

journal_title：Cancer

authors： Zelefsky MJ,Scher HI,Krol G,Portenoy RK,Leibel SA,Fuks ZY

更新日期：1992-11-01 00:00:00

abstract：BACKGROUND:Nineteen patients with Ewing sarcoma of bone, each younger than 3 years of age at the time of initial presentation, are reported. These children represent an unusually young age group for documented Ewing sarcoma and represent 2.6% of all patients registered in the Intergroup Ewing's Sarcoma Study (IESS). M...

journal_title：Cancer

authors： Maygarden SJ,Askin FB,Siegal GP,Gilula LA,Schoppe J,Foulkes M,Kissane JM,Nesbit M

更新日期：1993-03-15 00:00:00

abstract：:Mixed cellularity Hodgkin's disease and diffuse non-Hodgkin's lymphoma, mixed cell type, occurred consecutively in a husband and wife. Both patients demonstrated monoclonal IgM gammopathies. The unusual nature and possible significance of these findings are discussed. ...

journal_title：Cancer

authors： Offit K,Macris NT,Hellman G,Rotterdam HZ

更新日期：1986-01-15 00:00:00