Phase I evaluation of docetaxel and topotecan for patients with advanced solid tumors.

abstract：:The reported results from throughout the world of modern treatment of testicular seminoma are reviewed for the various clinical stages of disease. The three-year survival rate for 1,346 patients with Stage 1 and 2 disease is 91%. Since the review reveals considerable differences in staging methods, a clinically useful...

journal_title：Cancer

authors： Caldwell WL,Kademian MT,Frias Z,Davis TE

更新日期：1980-04-01 00:00:00

abstract：:The physiologic consequences of malnutrition in children with cancer are reviewed. It is stressed that the child with cancer has a nutritional state that is no different from the average population from which the child comes. What little malnutrition is seen is calorie malnutrition. The physiologic consequences are th...

journal_title：Cancer

authors： van Eys J

更新日期：1986-10-15 00:00:00

abstract：BACKGROUND:The psychological adaptation to a cancer diagnosis is characterized by significant distress. Although distress levels in cancer patients have been reported to be the highest shortly after diagnosis and before treatment, few attempts have been made to study emotional adjustment during the diagnostic period of...

journal_title：Cancer

authors： Perczek RE,Burke MA,Carver CS,Krongrad A,Terris MK

更新日期：2002-06-01 00:00:00

abstract：:Immunoproliferative small intestinal diseases (IPSID), previously known as Mediterranean Lymphomas, constitute more than 60% of the non-Burkitt's small intestinal lymphomas in Tunisia. A multidisciplinary study of IPSID was undertaken by the Tunisian/French Lymphoma Study Group in 1980 to reach a better understanding ...

journal_title：Cancer

authors： Tabbane F,Mourali N,Cammoun M,Najjar T

更新日期：1988-04-15 00:00:00

abstract：:Survivors of pediatric and young adult cancers remain at risk for subsequent diseases, including those related to human papillomavirus (HPV) infection. Prevention of HPV acquisition through vaccination has become possible over the last decade. HPV vaccines have been shown to be safe and effective, yet rates of vaccina...

journal_title：Cancer

authors： Temkin SM,Seibel NL

更新日期：2015-10-01 00:00:00

abstract：:The pancreatographic appearance and the clinical presentation of ten patients presenting with adenocarcinoma of the head of the pancreas coexisting with chronic pancreatitis were compared with those of 45 patients with chronic pancreatitis (CP), without malignancy, investigated at the same time period. All ten patient...

journal_title：Cancer

authors： Shemesh E,Czerniak A,Nass S,Klein E

更新日期：1990-02-15 00:00:00

abstract：:A distinctive glycopeptide, which acts as an acceptor for a cancer-associated galactosyltransferase, has been detected in sera and effusions of patients with extensive carcinoma. Cancer-associated galactosyltransferase acceptor (CAGA) purified from human malignant effusions was tested for its effects on cell growth in...

journal_title：Cancer

authors： Podolsky DK,Isselbacher KJ

更新日期：1980-03-15 00:00:00

abstract：BACKGROUND:A diagnosis of cancer provides a teachable moment in which a physician can counsel or teach the patient. The Cancer and Leukemia Group B hypothesized that this teachable moment could also be used to encourage counseling of the patients' relatives who smoke. The authors' first study sought to determine the fe...

journal_title：Cancer

authors： Schilling A,Conaway MR,Wingate PJ,Atkins JN,Berkowitz IM,Clamon GH,DiFino SM,Vinciguerra V

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND:Hispanics comprise almost one-third of the population of California, are the most rapidly increasing racial/ethnic group in the state, and represent almost one-third of all Hispanics in the U.S. California has among the highest rates of melanoma in the world, yet little is known about trends in melanoma in i...

journal_title：Cancer

authors： Cockburn MG,Zadnick J,Deapen D

更新日期：2006-03-01 00:00:00

abstract：:We report the clinical and pathologic features of two cases of adenosarcoma. Our first case occurred in the ovary of a 51-year-old woman with extensive pelvic involvement. She was treated vigorously with radiation and chemotherapy and at the present time almost 9 years later the patient is free of disease. This repres...

journal_title：Cancer

authors： Valdez VA,Planas AT,Lopez VF,Goldberg M,Herrera NE

更新日期：1979-04-01 00:00:00

abstract：:Two patients fulfilled the clinical and hematologic criteria for B-cell acute lymphoblastic leukemia: the malignant cells had L3 morphology, bore B-cell markers, and carried the specific t(8;14) translocation. The leukemic cells of one patient were tetrasomic for 1q, and those of the other patient showed several separ...

journal_title：Cancer

authors： Morris CM,Fitzgerald PH,Neville MA,Wyld PJ,Beard ME

更新日期：1984-07-01 00:00:00

abstract：BACKGROUND:Cancer rates in immigrant populations are frequently found to be intermediate between the country of origin and the adopted country. Such observations play an important role in establishing the environmental origin of cancer. Chinese now constitute the third largest group immigrating to New York City. METHO...

journal_title：Cancer

authors： Stellman SD,Wang QS

更新日期：1994-02-15 00:00:00

abstract：:From 1959 to 1986, 24 patients with primary malignant tumors of the trachea received radiotherapy as all or part of treatment. Common presentations included respiratory symptoms in 20 patients and hemoptysis in 15. Thirteen patients had squamous carcinomas with undifferentiated and adenoid cystic cancers in five and f...

journal_title：Cancer

authors： Fields JN,Rigaud G,Emami BN

更新日期：1989-06-15 00:00:00

abstract：:New approaches are needed in the treatment of advanced breast cancer. In vitro studies have shown that recombinant tumor necrosis factor (TNF) is a growth inhibitor for the MCF-7, ZR-75-1, and BT-20 human breast cancer cell lines. Based on these considerations, the Southwest Oncology Group performed a Phase II trial o...

journal_title：Cancer

authors： Budd GT,Green S,Baker LH,Hersh EP,Weick JK,Osborne CK

更新日期：1991-10-15 00:00:00

abstract：:Four cell lines were derived from childhood malignancies: rhabdomyosarcoma, sarcoma, lymphosarcoma and an American Burkitt's lymphoma. Cells of the four lines formed tumors in immunosuppressed newborn hamsters. The tumors had a microscopic appearance like that of the tumors from which the cell lines were derived. No ...

journal_title：Cancer

authors： McAllister RM,Nelson-Rees WA,Peer M,Laug WE,Isaacs H Jr,Gilden RV,Rongey RW,Gardner MB

更新日期：1975-11-01 00:00:00

abstract：BACKGROUND:Despite an increasing interest in the clinical application of positron emission tomography (PET) in tumors of the adult patient as a diagnostic and prognostic tool, only a few studies have been concerned with the usefulness of PET with [18F]2-deoxy-2-fluoro-D-glucose (FDG) in childhood tumors. METHODS:Fifte...

journal_title：Cancer

authors： Holthoff VA,Herholz K,Berthold F,Widemann B,Schröder R,Neubauer I,Heiss WD

更新日期：1993-08-15 00:00:00

abstract：BACKGROUND:CXC chemokine receptor 4 (CXCR4) is activated by phosphorylation (pCXCR4) and is essential for the migration of hematopoietic precursors to bone marrow. CXCR4 overexpression predicts a poor prognosis in patients with acute myeloid leukemia. Data regarding the prognostic impact of CXCR4 in patients with B-acu...

journal_title：Cancer

authors： Konoplev S,Jorgensen JL,Thomas DA,Lin E,Burger J,Kantarjian HM,Andreeff M,Medeiros LJ,Konopleva M

更新日期：2011-10-15 00:00:00

abstract：BACKGROUND:Central neurocytomas are composed of mature neuronal elements, frequently arranged in rosettes similar to those present in pineocytomas. This suggests the possibility of similar patterns of differentiation, including photoreceptor differentiation. The authors analyzed the immunoreactivity of central neurocyt...

journal_title：Cancer

authors： Mena H,Morrison AL,Jones RV,Gyure KA

更新日期：2001-01-01 00:00:00

abstract：:The results of nine US multicenter, sequential crossover, dose titration studies of controlled-release oral morphine (MS Contin 30 mg tablets [MSC], Purdue Frederick, Norwalk, CT) are reviewed in Part I. The studies demonstrated the prolonged analgesic efficacy of the preparation in the treatment of patients with mode...

journal_title：Cancer

authors： Kaiko RF,Grandy RP,Oshlack B,Pav J,Horodniak J,Thomas G,Ingber E,Goldenheim PD

更新日期：1989-06-01 00:00:00

abstract：:Of 387 patients who died with lung cancer, 28 cases were reviewed (7.2%) which were clinically undiagnosed. The male:female ratio was 3.6 and mean age was 64 years in the males, 47 years in the females. The most frequent presenting symptoms were neurologic. Prior to death, 21 patients had known or suspected metastatic...

journal_title：Cancer

authors： Clary CF,Michel RP,Wang NS,Hanson RE

更新日期：1983-01-15 00:00:00

abstract：BACKGROUND:Health insurance is a key mediator of health care disparities. Outcomes in bladder cancer, one of the costliest diseases to treat, may be especially sensitive to a patient's insurance status. METHODS:The Surveillance, Epidemiology, and End Results registry and the National Cancer Data Base were used to iden...

journal_title：Cancer

authors： Fletcher SA,Cole AP,Lu C,Marchese M,Krimphove MJ,Friedlander DF,Mossanen M,Kilbridge KL,Kibel AS,Trinh QD

更新日期：2020-02-01 00:00:00

abstract：BACKGROUND:The demonstration of the monoclonality of immunoglobulin heavy chain (IgH) gene rearrangement is an indispensable method for the diagnosis of B-cell lymphoma as well as histocytochemical analysis. For the detection of IgH gene rearrangement, the extraction of DNA from a homogenous cell population is necessar...

journal_title：Cancer

authors： Orba Y,Tanaka S,Nishihara H,Kawamura N,Itoh T,Shimizu M,Sawa H,Nagashima K

更新日期：2003-08-25 00:00:00

abstract：BACKGROUND:Gastrointestinal stromal tumors (GISTs) are a specific clinicopathologic entity characterized by activating mutations in the c-KIT gene. These mutations are associated with increased immunohistochemical staining for the c-KIT protein. Because many GISTs display a definitive response to the KIT inhibitor imat...

journal_title：Cancer

authors： Willmore-Payne C,Layfield LJ,Holden JA

更新日期：2005-06-25 00:00:00

abstract：BACKGROUND:Despite significant advances in understanding the biology of renal cell carcinoma (RCC) during the past decade, metastatic disease remains nearly incurable and a major medical challenge. Because RCC is known to be immunogenic, immunotherapeutic agents such as recombinant human interleukin-2 (rIL-2) and inter...

journal_title：Cancer

authors： Bukowski RM

更新日期：1997-10-01 00:00:00

abstract：BACKGROUND:Commonly used chemotherapies can be toxic to the ovaries. To the authors' knowledge, the majority of studies evaluating receipt of fertility counseling for women in their reproductive years have been performed in specific settings, thereby limiting generalizability. METHODS:A nationwide sample of US women d...

journal_title：Cancer

authors： Hawkins Bressler L,Mersereau JE,Anderson C,Rodriguez JL,Hodgson ME,Weinberg CR,Sandler DP,Nichols HB

更新日期：2019-08-01 00:00:00

abstract：BACKGROUND:Myelodysplastic syndromes (MDS) appear to be underreported to cancer registries, with important implications for cancer and transfusion support service planning and delivery. Two population-based databases were linked to estimate MDS incidence more accurately. METHODS:Data from the statewide Victorian Cance...

journal_title：Cancer

authors： McQuilten ZK,Wood EM,Polizzotto MN,Campbell LJ,Wall M,Curtis DJ,Farrugia H,McNeil JJ,Sundararajan V

更新日期：2014-06-01 00:00:00

abstract：BACKGROUND:In a randomized Phase II study, the authors evaluated the activity and toxicity of the new cisplatin, doxorubicin, and mitomycin C (PAM) combination, that includes cisplatin (P) instead of 5-fluorouracil as in the 5-fluorouracil, doxorubicin, and mitomycin C (FAM) combination, in patients with advanced gastr...

journal_title：Cancer

authors： De Lisi V,Cocconi G,Angelini F,Cavicchi F,Di Costanzo F,Gilli G,Rodinò C,Soldani M,Tonato M,Finardi C

更新日期：1996-01-15 00:00:00

abstract：:The body composition of 23 patients with cachexia resulting from malignant or benign inflammatory disease was studied. Skinfold thickness and radioisotope tracer measurements enabled us to estimate total body fat, lean body mass, the ratio of fat loss to lean body loss, erythrocyte and plasma volumes, total body water...

journal_title：Cancer

authors： Watson WS,Sammon AM

更新日期：1980-11-01 00:00:00

abstract：:Histologic features similar to those present in angiosarcomas were found in organizing thrombi. Within the thrombi, freely anastomosing small channels, often lined by one or more layers of prominent, occasionally atypical, endothelial cells were noted. Papillary-like projections of organizing thrombus material lined b...

journal_title：Cancer

authors： Salyer WR,Salyer DC

更新日期：1975-09-01 00:00:00

abstract：:Formal cancer survivorship care is a growing focus internationally. This article provides a broad overview of the national strategies currently in progress for the development of survivorship programs and care plans within the United States and across Europe. The different approaches taken in their implementation, sta...

journal_title：Cancer

authors： McCabe MS,Faithfull S,Makin W,Wengstrom Y

更新日期：2013-06-01 00:00:00