Abstract:
:Immunoproliferative small intestinal diseases (IPSID), previously known as Mediterranean Lymphomas, constitute more than 60% of the non-Burkitt's small intestinal lymphomas in Tunisia. A multidisciplinary study of IPSID was undertaken by the Tunisian/French Lymphoma Study Group in 1980 to reach a better understanding of the two subgroups of the disease: secreting IPSID (essentially alpha-chain disease [ACD]); and nonsecreting IPSID (NS-IPSID) (extensive small intestinal lymphomas without gammopathy). The results of initial exploratory laparotomy performed in 38 cases of IPSID (17 ACD and 21 NS-IPSID) are described here, and show notable similarities between the two groups: the extensive pattern of the abnormal cell infiltrate along the major part of the small intestine; frequent and extensive involvement of the mesenteric lymph nodes; the existence of several degrees of severity in small intestinal mesenteric lymph nodes; and other intraabdominal organ involvement. Certain differences also were observed: the relatively high degree of tropism of the NS-IPSID towards the gastric mucosa which was absent in the ACD of this series; and the more frequent involvement of the entire length of the small bowel in ACD. In spite of these discrete differences, the IPSID form a homogeneous group which is definitely distinguishable from the segmentary small intestinal lymphomas known as Western-type, and which account for approximately one third of our non-Burkitt's small bowel lymphomas.
journal_name
Cancerjournal_title
Cancerauthors
Tabbane F,Mourali N,Cammoun M,Najjar Tdoi
10.1002/1097-0142(19880415)61:8<1699::aid-cncr2820subject
Has Abstractpub_date
1988-04-15 00:00:00pages
1699-706issue
8eissn
0008-543Xissn
1097-0142journal_volume
61pub_type
杂志文章相关文献
CANCER文献大全abstract::Seventeen patients with carcinoma confined to the pancreas and the peripancreatic area received preoperative radiation therapy in an attempt to increase the resectability rate and to reduce the incidence of recurrence. The tumors were considered either unresectable or of borderline resectability. The radiation dose ra...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19801101)46:9<1945::aid-cncr2820
更新日期:1980-11-01 00:00:00
abstract:BACKGROUND:The induction of estrogen and progesterone receptors (ER and PGR) has been reported in breast and endometrial cancer cells exposed to human fibroblast interferon-beta (hIFN-beta). Clinical verification of this finding might provide the rationale for new therapeutic approaches. This study was designed to eval...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/(SICI)1097-0142(19960801)78:3<448::AID-CNC
更新日期:1996-08-01 00:00:00
abstract::A case of a patient with a metastatic ACTH (adrenocorticotrophic hormone)-producing gastric carcinoid APUD (amine precursor uptake and decarboxylation) tumor is presented. The patient presented with Cushing's syndrome and very high levels of ACTH. The Cushing's syndrome was controlled medically, and when the patient d...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19800901)46:5<1263::aid-cncr2820
更新日期:1980-09-01 00:00:00
abstract:BACKGROUND:Treatment outcomes were analyzed for retromolar trigone squamous cell carcinoma. METHODS:Between June 1966 and August 2003, 99 patients were treated with radiotherapy alone (35 patients) or radiotherapy combined with surgery (64 patients). Followup ranged from 0.2 to 23.8 years (median, 3.3 yrs). All living...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.21038
更新日期:2005-06-01 00:00:00
abstract::Karyotypes from seven patients with thyroid lymphoma were studied before treatment. When the cytogenetic results were correlated with the clinical data, it became evident that there are two distinct groups of patients with thyroid lymphoma. In a group of patients with solely numerical abnormalities the disease is asso...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19890301)63:5<873::aid-cncr28206
更新日期:1989-03-01 00:00:00
abstract::We examined resected specimens from 40 cases of advanced rectal cancer to determine the extent of microtubular cancer nests and undifferentiated cancer cells (budding). We investigated the relationship between this budding and lymphatic invasion (ly), venous invasion (v), and lymph node metastasis (n), respectively. M...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19890201)63:3<539::aid-cncr28206
更新日期:1989-02-01 00:00:00
abstract:BACKGROUND:Pathologically, benign prostatic hyperplasia (BPH) is not considered a precursor for prostate carcinoma. However, because the two conditions share not only a similar hormonal environment within the prostate but also several common risk factors, it is possible that men with BPH may be at increased risk of pro...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.11710
更新日期:2003-10-15 00:00:00
abstract::The multiple classifications of histiocytic disorders, and the lack of specificity in their application, have degraded the utility of such diagnostic terms as "Letterer-Siwe Disease" and "Malignant Histiocytosis". A case is presented of a systemic histiocytic proliferation with erythrophagocytosis and giant-cell forma...
journal_title:Cancer
pub_type: 杂志文章,评审
doi:10.1002/1097-0142(197612)38:6<2529::aid-cncr282038
更新日期:1976-12-01 00:00:00
abstract:BACKGROUND:The authors analyzed the outcomes of patients treated with radiotherapy (RT) alone or combined with surgery for carcinoma of the salivary glands. METHODS:Between October 1964 and June 2003, 224 previously untreated patients were treated with curative intent with RT alone (n = 64) or combined with surgery (n...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.21083
更新日期:2005-06-15 00:00:00
abstract::There were no significant differences between the mean blood plasma (leukocyte-free) RNAase activity among 128 healthy women volunteers age 13-70 and 49 women with benign gynecological tumors. Exceptions to this finding were three apparently healthy women volunteers who had plasma enzyme activity which was higher than...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(197705)39:5<2204::aid-cncr282039
更新日期:1977-05-01 00:00:00
abstract::Surgery is the most effective treatment for thyroid cancer; however, in some subsets of patients, the role of radiotherapy (RT) is important. The main indication for external-beam RT is incomplete surgery. When neoplastic tissue is left behind at operation, RT must be considered, but only if an experienced surgeon fee...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19850501)55:9+<2062::aid-cncr282
更新日期:1985-05-01 00:00:00
abstract:BACKGROUND:In preclinical Ewing sarcoma (ES) models, poly(adenosine diphosphate ribose) polymerase (PARP) inhibitors were identified as a potential therapeutic strategy with synergy in combination with cytotoxic agents. This study evaluated the safety and dosing of the PARP1/2 inhibitor niraparib (NIR) with temozolomid...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.33349
更新日期:2020-12-08 00:00:00
abstract:BACKGROUND:Between January 11, 1991 and January 8, 1992, 104 patients with previously untreated, invasive, primitive breast carcinoma were admitted to the authors' hospital. METHODS:For each patient, flow cytometry DNA analyses on frozen samples and on immunohistochemical staining were performed, including Ki-67, cycl...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.11209
更新日期:2003-03-15 00:00:00
abstract:BACKGROUND:Validation of the prognostic indices for the recurrence-free interval of patients with parotid carcinoma, the development of which was described in a previous report, is needed to be confident of their generalizability and justified prospective use. METHODS:The Dutch Cooperative Group on Head and Neck Cance...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.11254
更新日期:2003-03-15 00:00:00
abstract:BACKGROUND:Childhood cancer is a highly curable disease when timely diagnosis and appropriate therapy are provided. A negative impact of the coronavirus disease 2019 (COVID-19) pandemic on access to care for children with cancer is likely but has not been evaluated. METHODS:A 34-item survey focusing on barriers to ped...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.33075
更新日期:2020-09-15 00:00:00
abstract::Diagnostic advances currently have exceeded therapeutic gain. The present, however, is a transition phase. Chemotherapy, for example, has become curative for some tumors in recent years, rather than merely palliative, due to the precision permitted by advances in molecular biology. At this time, acceleration in the ba...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19901015)60:8+<1931::aid-cncr282
更新日期:1987-10-15 00:00:00
abstract:BACKGROUND:Reports on lymphoid malignancy and its treatment in children infected with human immunodeficiency virus (HIV) are limited. METHODS:Antibodies to Epstein-Barr virus (EBV) were detected by indirect immunofluorescence. DNA was extracted from peripheral blood lymphocytes or biopsy specimens. Polymerase chain re...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19940101)73:1<224::aid-cncr28207
更新日期:1994-01-01 00:00:00
abstract::Two children with Wilms' tumor and prior thoracic radiation developed congestive heart failure at cumulative adriamycin doses of 350 mg/m2 and 400 mg/m2. Details of these two cases and a summary of previously reported adriamycin cardiotoxicity in children are presented. Dose recommendations and predictive tests are di...
journal_title:Cancer
pub_type: 杂志文章,评审
doi:10.1002/1097-0142(197701)39:1<62::aid-cncr28203901
更新日期:1977-01-01 00:00:00
abstract::A study of primary epithelial neoplasms of the appendix (with the exception of classical carcinoids), produced 24 adenocarcinomas and 42 benign lesions from the files of the Laboratory of Surgical Pathology of Columbia University. Invasive adenoarcinomas were often complicated by appendicitis and were then unexpectedl...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(197605)37:5<2493::aid-cncr282037
更新日期:1976-05-01 00:00:00
abstract::In three cases of the spontaneous rupture of hepatocellular carcinoma, emergent transcatheter hepatic arterial embolization was performed for controlling the intraperitoneal hemorrhage. No more transfusions were required after embolization. Operation was carried out on the 10th, 5th, and 5th day, respectively, after l...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19860715)58:2<332::aid-cncr28205
更新日期:1986-07-15 00:00:00
abstract::Granulocyte (PMN) directional locomotion (migration) in vitro and in vivo, resting nitroblue tetrazolium (NBT)-reduction and adherence to nylon wool of polymorphonuclear neutrophils (PMN) were assayed in 7 patients with Hodgkin's disease (HD) and in 11 patients with non-Hodgkin's lymphoma (NHL) prior to therapy. In mo...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19800201)45:3<469::aid-cncr28204
更新日期:1980-02-01 00:00:00
abstract::The effect of cis-diamminedichloroplatinum II (DDP) and ionizing radiation on human bladder transitional cell carcinoma (TCC) was evaluated in nude mouse-grown human tumors following administration of single-agent and combination treatment. Combination of DDP and radiation resulted in accelerated tumor regression and ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19830801)52:3<452::aid-cncr28205
更新日期:1983-08-01 00:00:00
abstract::With the improved survival of children with cancer, increased attention is being focused on the health status of survivors. The ultimate objective of this research is to use the results to design and test rational intervention strategies directed toward reduction of morbidity and mortality associated with the diagnosi...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19930515)71:10+<3406::aid-cncr28
更新日期:1993-05-15 00:00:00
abstract:BACKGROUND:Studies regarding different ethnic populations of children with Wilms' tumor (WT) in the U. S. have shown differences between age and gender incidence and the type of its precursor lesions (nephrogenic rests). To the authors' knowledge there are few reports in the literature regarding nephrogenic rests in a ...
journal_title:Cancer
pub_type: 杂志文章,多中心研究
doi:
更新日期:1998-11-15 00:00:00
abstract::The frequency and significance of hyperprolactinemia was studied in 21 consecutive, untreated male patients with bronchogenic carcinoma. Seven patients (33%) were found to have elevated serum prolactin (hPRL) levels. No correlation was demonstrated between increased hPRL levels, tissue histology, or tumor burden. L-do...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(197908)44:2<676::aid-cncr2820440
更新日期:1979-08-01 00:00:00
abstract::An unusual thyroid carcinoma is described, showing structural, histochemical and radioimmunologic features of both a follicular and a parafollicular cell carcinoma. Radioimmunoassay revealed high levels of thyroglobulin in the patient's serum and in extracts from metastatic tumor tissue. Immunoreactive thyroglobulin w...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19830915)52:6<1053::aid-cncr2820
更新日期:1983-09-15 00:00:00
abstract:BACKGROUND:Postprostatectomy adjuvant or salvage radiotherapy, when using standard fractionation, requires 6.5 to 8 weeks of treatment. The authors report on the safety and efficacy of an expedited radiotherapy course for salvage prostate radiotherapy. METHODS:A total of 108 consecutive patients were treated with salv...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.25824
更新日期:2011-06-15 00:00:00
abstract::Thirty-seven lymphomas of bone were studied, including 33 diffuse large cell lymphomas, three undifferentiated (small noncleaved cell) lymphomas, and one well-differentiated (small) lymphocytic lymphoma. The large cell lymphomas were subclassified as large cleaved, large noncleaved, multilobated cell, and immunoblasti...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19871115)60:10<2494::aid-cncr282
更新日期:1987-11-15 00:00:00
abstract::Twelve cases of thymic carcinoid were studied by electron microscopy and immunohistochemistry. Clinically, all of them presented either as asymptomatic, radiographically detected mediastinal masses or as neoplasms producing symptoms of thoracic structural displacement or Cushing's syndrome. By light microscopic examin...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19840201)53:3<475::aid-cncr28205
更新日期:1984-02-01 00:00:00
abstract::Among the patients showing evidence of cerebral metastases without previously known cancer history, lung cancer has been found 37 times as the primary tumor in our institution. There were 34 men and three women and all but two were heavy smokers. Only one presented at diagnosis with thoracic symptoms but the chest rad...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19910601)67:11<2935::aid-cncr282
更新日期:1991-06-01 00:00:00