Abstract:
:Two children with Wilms' tumor and prior thoracic radiation developed congestive heart failure at cumulative adriamycin doses of 350 mg/m2 and 400 mg/m2. Details of these two cases and a summary of previously reported adriamycin cardiotoxicity in children are presented. Dose recommendations and predictive tests are discussed.
journal_name
Cancerjournal_title
Cancerauthors
Prout MN,Richards MJ,Chung KJ,Joo P,Davis HL Jrdoi
10.1002/1097-0142(197701)39:1<62::aid-cncr28203901subject
Has Abstractpub_date
1977-01-01 00:00:00pages
62-5issue
1eissn
0008-543Xissn
1097-0142journal_volume
39pub_type
杂志文章,评审相关文献
CANCER文献大全abstract:BACKGROUND:Methotrexate is a chemotherapeutic agent frequently utilized for the treatment of malignant, rheumatic, and pulmonary diseases. Although this agent has been extensively used for more than 45 years, there are few reports of immediate systemic hypersensitivity reactions. The reported immediate reactions includ...
journal_title:Cancer
pub_type: 杂志文章,评审
doi:10.1002/(SICI)1097-0142(19960515)77:10<2123::AID-C
更新日期:1996-05-15 00:00:00
abstract::In a 10-year incidence survey of breast cancer in the City of Boston, 14 cases in American Chinese women were observed, while approximately 13 were expected on the basis of age-specific incidence in the white population. In Hawaii, on the other hand, while breast cancer incidence rates for ethnic Chinese are approxima...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19840101)53:1<187::aid-cncr28205
更新日期:1984-01-01 00:00:00
abstract::The cytologic, histologic and ultrastructural features of a malignant carcinomatous mesothelioma of the tunica vaginalis testis in a 30-year old patient are described. This is the first such case with preoperative diagnosis by cytologic examination of hydrocele fluid and the second with documented history of exposure ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19820101)49:1<119::aid-cncr28204
更新日期:1982-01-01 00:00:00
abstract::High tissue concentrations of human chorionic gonadotropin (hCG) and alpha-fetoprotein (AFP) were revealed by radioimmunoassay in a hepatic tumor which was surgically removed from a two-year, eight-month-old boy manifesting sexual precocity. Histologically the tumor showed an embryonal type hepatoblastoma admixed with...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19830501)51:9<1647::aid-cncr2820
更新日期:1983-05-01 00:00:00
abstract::Two hundred and forty patients, asymptomatic relative to gastrointestinal disease, who applied for elective hernia repair, were tested as outpatients for occult blood in the stool. Thirty-eight patients had one or more positive specimens. Significant pathologic characteristics were identified by lower gastrointestinal...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19830401)51:7<1261::aid-cncr2820
更新日期:1983-04-01 00:00:00
abstract::We detected cytoplasmic estrogen receptors (ER) in only 4 of 34 (12%) patients with malignant melanoma. The titers as assayed by the dextran-coated charcoal method were 3, 3, 4, and 5 fmol/mg, respectively. Our data indicate that the incidence of melanoma with detectable ER is low, which suggests that any potential cl...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19801015)46:8<1785::aid-cncr2820
更新日期:1980-10-15 00:00:00
abstract:BACKGROUND:Young adults have historically been the least likely to have health insurance in the United States. Previous studies of survivors of childhood cancer found lower rates of insurance and less access to medical care compared with siblings; however, to the authors' knowledge, no studies to date have examined con...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.28685
更新日期:2014-08-01 00:00:00
abstract:BACKGROUND:Greater than one-half of children who are treated for acute lymphoblastic leukemia (ALL) develop ≥1 treatment-related medical conditions in their lifetime, many of which are known risk factors for diabetes mellitus. In the current study, the authors evaluated the prevalence and risk factors of diabetes melli...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.32596
更新日期:2020-02-15 00:00:00
abstract::The epidemiologic pattern for Hodgkin's disease in blacks from two different communities in the United States was characterized by higher childhood rates and significantly lower rates in the young adult and older age groups than for whites. In addition, a significantly greater number of black patients belonged to low ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(197712)40:6<3133::aid-cncr282040
更新日期:1977-12-01 00:00:00
abstract:BACKGROUND:Data suggest that vitamin D plays a role in the treatment and prevention of prostate cancer. The combination of high-dose, intermittent calcitriol (1,25 dihydroxyvitamin D3) plus dexamethasone was studied based on evidence that dexamethasone potentiates the antitumor effects of calcitriol and ameliorates hyp...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.21890
更新日期:2006-05-15 00:00:00
abstract::The prognostic significance of histologic tumor grade has been evaluated in 1537 women entered into the Ludwig Trials I-IV of adjuvant therapy for node-positive breast cancer. Tumor grade was determined on histologic review of primary tumor sections by two central review pathologists using a modification of the Bloom ...
journal_title:Cancer
pub_type: 临床试验,杂志文章
doi:10.1002/1097-0142(19861215)58:12<2662::aid-cncr282
更新日期:1986-12-15 00:00:00
abstract::The dose of adjuvant chemotherapy for breast cancer may be an important factor in the success of the treatment program. In a retrospective analysis, the authors determined whether patients who were irradiated either postoperatively (N = 29) or as part of primary treatment (N = 13) received a lower dose of adjuvant cyc...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19840115)53:2<237::aid-cncr28205
更新日期:1984-01-15 00:00:00
abstract::The authors administered high-dose chemotherapy with cyclophosphamide, BCNU (carmustine) and VP-16 (etoposide) plus autologous bone marrow transplantation (ABMT) to 22 adult patients with relapsed acute leukemia in second or subsequent remission. The marrow was not treated ex vivo. The long-term, disease-free survival...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19900815)66:4<619::aid-cncr28206
更新日期:1990-08-15 00:00:00
abstract::Cancer is the second most common cause of death among those aged > or =65 years, and is a major cause of morbidity. There is some evidence that screening, by detecting precancerous lesions in asymptomatic patients, is effective in reducing cancer-related morbidity and mortality among older men and women. The objective...
journal_title:Cancer
pub_type: 杂志文章,评审
doi:10.1002/cncr.23938
更新日期:2008-12-15 00:00:00
abstract:BACKGROUND:Hepatocellular carcinoma (HCC) with portal venous invasion (PVI) has a very poor prognosis, with a median survival of 3 months and virtually no survival at 1 year. The combination of intraarterial 5-fluorouracil (FU) and systemic interferon-alpha (IFNalpha) was recently reported to be effective against HCC w...
journal_title:Cancer
pub_type: 临床试验,杂志文章
doi:10.1002/cncr.21832
更新日期:2006-05-01 00:00:00
abstract:BACKGROUND:Partial nephrectomy (PN) is recommended for localized T1a (≤4 cm) renal masses and is preferred over radical nephrectomy (RN) for amenable T1b/T2 (>4 cm) tumors. The objective of the current study was to assess overall survival (OS) differences between PN and RN in patients with T1 and T2 renal cell carcinom...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.31582
更新日期:2018-10-01 00:00:00
abstract:BACKGROUND:Postprostatectomy adjuvant or salvage radiotherapy, when using standard fractionation, requires 6.5 to 8 weeks of treatment. The authors report on the safety and efficacy of an expedited radiotherapy course for salvage prostate radiotherapy. METHODS:A total of 108 consecutive patients were treated with salv...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.25824
更新日期:2011-06-15 00:00:00
abstract::The purpose of this study is to evaluate benign and/or malignant thyroid tumors with 201TI thyroid scan. We studied 76 cases of histologically verified thyroid tumors, all seen as cold nodules on the 123I thyroid scan. 201TI thyroid scan was performed 5-15 minutes (early scan) and 3-5 hours (delayed scan) after intrav...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19820715)50:2<236::aid-cncr28205
更新日期:1982-07-15 00:00:00
abstract::A useful approach to establishing the biologic actions, in vivo, of granulocyte-macrophage colony-stimulating factor (GM-CSF) is to assess the consequences of long-term elevation of the factor in transgenic mice. Two lines of transgenic GM-CSF mice were analyzed. The major abnormality exhibited was an elevation in the...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19910515)67:10+<2695::aid-cncr28
更新日期:1991-05-15 00:00:00
abstract:BACKGROUND:A clinicopathologic evaluation of clinical Stage I and II uterine sarcoma was done by the Gynecologic Oncology Group from 1979-1988. METHODS:After all eligibility criteria were met, 453 cases were evaluable and analyzed for prognostic factors. RESULTS:Of the 301 mixed mesodermal tumors (MMT), 167 were homo...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.2820710440
更新日期:1993-02-15 00:00:00
abstract::Human cases autopsied at the Department of Pathology, University of Tokyo, were studied to investigate the chronologic changes in the relationship between cigarette smoking and lung cancer occurrence. The results obtained were as follows: (1) it was confirmed that the incidence of lung cancer was significantly higher ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19840915)54:6<1038::aid-cncr2820
更新日期:1984-09-15 00:00:00
abstract:BACKGROUND:The objective of this study was to investigate whether polymorphisms in DNA repair genes affect clinical outcome of never-smokers with lung adenocarcinoma (NSLA). METHOD:Common polymorphisms in the DNA repair genes ribonucleotide reductase M1 (RRM1), excision repair cross-complementation group 1 (ERCC1), an...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.25863
更新日期:2011-07-15 00:00:00
abstract:BACKGROUND:Cancer clinicians do not receive routine training in the psychosocial aspects of patient care such as how to communicate bad news or respond to patients who have unrealistic expectations of cure. Postgraduate workshops may be an effective way to increase interpersonal skills in managing these stressful patie...
journal_title:Cancer
pub_type: 杂志文章
doi:
更新日期:1999-09-01 00:00:00
abstract::Although weight loss has an adverse impact on cancer patient survival, the ability of caloric provision via total parenteral nutrition (TPN) to favorably influence outcome in chemotherapy-treated populations is not established. In randomized trials, no significant improvement in either response or survival was associa...
journal_title:Cancer
pub_type: 临床试验,杂志文章,评审
doi:10.1002/1097-0142(19850101)55:1+<268::aid-cncr2820
更新日期:1985-01-01 00:00:00
abstract:BACKGROUND:Breast carcinoma is one of the leading causes of excess mortality rates in Harlem, an inner-city neighborhood with the highest mortality rates and worst life expectancy in New York City. This study reports the results of a breast carcinoma screening and diagnostic program in Harlem. METHODS:Retrospective re...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.10640
更新日期:2002-07-01 00:00:00
abstract::Greatest surface diameter of a cancer, together with suspicion of regional node metastasis, forms the basis for prognosis through the clinical TNM staging system for many cancers. In oral cancer, however, surface size sometimes fails to correlate, or sometimes inversely correlates, with tumor aggressiveness. To shed l...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19860701)58:1<158::aid-cncr28205
更新日期:1986-07-01 00:00:00
abstract::A case report of a metastasizing basal cell carcinoma is presented, primary in the leg with regional inguinal lymph node metastasis, followed by extensive metastasis to skin and bone marrow with myelophthisic anemia and terminal splenohepatic and unilateral adrenal metastasis. ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(196810)22:4<879::aid-cncr2820220
更新日期:1968-10-01 00:00:00
abstract::Between 1968 and 1985, 28 patients with recurrent gestational trophoblastic disease (GTD) were treated at the Southeastern Regional Trophoblastic Disease Center. Sixteen patients received primary therapy at this center and had recurrence diagnosed by re-elevation of human chorionic gonadotropin (hCG) levels after thre...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19900901)66:5<978::aid-cncr28206
更新日期:1990-09-01 00:00:00
abstract::A patient with a primary adenohypophyseal neoplasm who had a long course marked by multiple surgical resections, radiation therapy, and high-dose dopamine agonist therapy developed local invasion as well as cranial and extracranial osseous metastatic lesions. The serum prolactin levels were greatly elevated, and immun...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19850201)55:3<598::aid-cncr28205
更新日期:1985-02-01 00:00:00
abstract:BACKGROUND:The authors examined the "real-world" effectiveness of rituximab (R) maintenance therapy (R-maintenance) compared with observation after R-based induction therapy in patients with previously untreated follicular lymphoma (FL) in the United States. METHODS:The National LymphoCare Study is a prospective, mult...
journal_title:Cancer
pub_type: 杂志文章,多中心研究
doi:10.1002/cncr.28659
更新日期:2014-06-15 00:00:00