Abstract:
:Histologic features similar to those present in angiosarcomas were found in organizing thrombi. Within the thrombi, freely anastomosing small channels, often lined by one or more layers of prominent, occasionally atypical, endothelial cells were noted. Papillary-like projections of organizing thrombus material lined by similar cells heightened the similarity of the process to angiosarcomas. The papillary-like structures appeared to develop due to a combination of endothelialization of thrombus fragments and of ingrowth of interlacing vessels. The peculiar process of thrombus organization, which has been called "intravascular angiomatosis," may be mistaken for true angiosarcoma and thus lead to unnecessary irradiation or radical surgery. The pseudoangiosarcoma differed from angiosarcoma in its confinement entirely within large vascular lumens and in its lack of mitoses, necrosis, and true solid cellular areas devoid of vascular differentiation.
journal_name
Cancerjournal_title
Cancerauthors
Salyer WR,Salyer DCdoi
10.1002/1097-0142(197509)36:3<995::aid-cncr2820360subject
Has Abstractpub_date
1975-09-01 00:00:00pages
995-1001issue
3eissn
0008-543Xissn
1097-0142journal_volume
36pub_type
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