Childhood sarcomas and lymphomas. Characterization of new cell lines and search for type-C virus.

Abstract:

:Four cell lines were derived from childhood malignancies: rhabdomyosarcoma, sarcoma, lymphosarcoma and an American Burkitt's lymphoma. Cells of the four lines formed tumors in immunosuppressed newborn hamsters. The tumors had a microscopic appearance like that of the tumors from which the cell lines were derived. No virus-like particles were detected by electron microscopy in the cell lines after treatment with bromodeoxyuridine; no hamster type-C virus expression was present in cell lines derived from the hamster tumors. Chromosome constitution and in vitro growth properties of the cell lines were studied as was the fibrinolytic function of the sarcoma lines.

journal_name

Cancer

journal_title

Cancer

authors

McAllister RM,Nelson-Rees WA,Peer M,Laug WE,Isaacs H Jr,Gilden RV,Rongey RW,Gardner MB

doi

10.1002/1097-0142(197511)36:5<1804::aid-cncr282036

subject

Has Abstract

pub_date

1975-11-01 00:00:00

pages

1804-14

issue

5

eissn

0008-543X

issn

1097-0142

journal_volume

36

pub_type

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