Facilitating clinical trials. The expanding role of the nurse.

abstract：BACKGROUND:There is an increase in the incidence of cutaneous malignant melanoma (CMM) among white people throughout the world. In Sweden, a fivefold increase has been recorded since 1960, but the mortality is rising at a much lower rate. Tumor thickness is the single most important prognostic factor for primary melano...

journal_title：Cancer

authors： Måsbäck A,Westerdahl J,Ingvar C,Olsson H,Jonsson N

更新日期：1994-03-15 00:00:00

abstract：:Peripheral blood lymphocytes of patients with multiple myeloma, macroglobulinemia, and monoclonal gammopathy of uncertain significance were analyzed for B cells, and cells bearing kappa light chains and lambda light chains on their surfaces. Compared with controls, the number of B cells were decreased in all three gro...

journal_title：Cancer

authors： Dillman RO,Royston I,Meserve BL,Griffiths JC

更新日期：1981-11-15 00:00:00

abstract：:Epidemiologic variables related to breast cancer risk were assessed in a case-control study of 332 women with breast carcinoma and 1353 comparison women. Risk factors for breast cancer as a whole included nulliparity, late age at first childbirth, early age at menarche, late age at menopause, personal history of benig...

journal_title：Cancer

authors： LiVolsi VA,Kelsey JL,Fischer DB,Holford TR,Mostow ED,Goldenberg IS

更新日期：1982-05-01 00:00:00

abstract：:Between July 1968 and December 1974, 53 patients with lung cancer were planned for preoperative irradiation and surgery. All patients were considered clinically marginally resectable because of advanced local disease, 4 Stage II patients, with limited pulmonary reserve and 49 Stage III patients. Most patients received...

journal_title：Cancer

authors： Sherman DM,Neptune W,Weichselbaum R,Order SE,Piro AJ

更新日期：1978-05-01 00:00:00

abstract：BACKGROUND:Although cervical carcinoma incidence and mortality rates have declined in the U.S. greatly since the introduction of the Papanicolaou smear, this decline has not been uniform for all histologic subtypes. Therefore, the authors assessed the differential incidence rates of squamous cell carcinoma (SCC) and ad...

journal_title：Cancer

authors： Wang SS,Sherman ME,Hildesheim A,Lacey JV Jr,Devesa S

更新日期：2004-03-01 00:00:00

abstract：BACKGROUND:Several of the large studies addressing prognosis and survival from hepatocellular carcinoma (HCC) have been from Europe and Asia, but only a few have emanated from North America. Survival statistics from other parts of the world may not be applicable to the North American population because of etiologic, de...

journal_title：Cancer

authors： Nzeako UC,Goodman ZD,Ishak KG

更新日期：1995-08-15 00:00:00

abstract：:A case of a dermal nerve sheath myxoma arising in a digital nerve is reported. Similar tumors and its variants have been termed neurothekeoma, pacinian neurofibroma, bizarre cutaneous neurofibroma, and plexiform neurofibroma. The perineural sheath or the Schwann cell have been presumed to be the cell of origin by seve...

journal_title：Cancer

authors： Blumberg AK,Kay S,Adelaar RS

更新日期：1989-03-15 00:00:00

abstract：BACKGROUND:Stereotactic radiation therapy is highly effective in the treatment of small brain metastases, regardless of the histology. This suggests that small extracranial malignancies may be curable with similar radiation therapy. The authors developed a novel treatment unit for administering such therapy. METHODS:T...

journal_title：Cancer

authors： Uematsu M,Shioda A,Tahara K,Fukui T,Yamamoto F,Tsumatori G,Ozeki Y,Aoki T,Watanabe M,Kusano S

更新日期：1998-03-15 00:00:00

abstract：:Increased in vitro tetraploidy occurred in skin cultures derived from all affected patients and some family members at risk studied in families with heritable colon cancer syndromes (15 of 16 Gardner syndrome families, three Oldfield syndrome families, and four families with heritable colon cancer syndrome without pol...

journal_title：Cancer

authors： Danes BS

更新日期：1981-10-01 00:00:00

abstract：BACKGROUND:Previous studies have suggested that the prognosis in patients with extremity soft-tissue sarcomas (ESTS) with isolated lymph node (LN) metastases (stage IV) is comparable to that of patients with high-risk ESTS without metastases (stage III). This study was performed to determine the outcomes of patients wh...

journal_title：Cancer

authors： Al-Refaie WB,Andtbacka RH,Ensor J,Pisters PW,Ellis TL,Shrout A,Hunt KK,Cormier JN,Pollock RE,Feig BW

更新日期：2008-04-15 00:00:00

abstract：:The DNA sequences around codons 12, 13, and 61 of the ras gene were analyzed by polymerase chain reaction and direct sequencing in 18 intrahepatic cholangiocarcinomas. The ras gene mutations were found in 9 of 18 (50%): 6 in K-ras codon 12, 1 in K-ras codon 13, 1 in K-ras codon 61, and 1 in N-ras codon 12. The inciden...

journal_title：Cancer

authors： Tada M,Omata M,Ohto M

更新日期：1992-03-01 00:00:00

abstract：BACKGROUND:We have often encountered difficulties in identifying small liver cancers during surgery. Fluorescent imaging using indocyanine green (ICG) has the potential to detect liver cancers through the visualization of the disordered biliary excretion of ICG in cancer tissues and noncancerous liver tissues compresse...

journal_title：Cancer

authors： Ishizawa T,Fukushima N,Shibahara J,Masuda K,Tamura S,Aoki T,Hasegawa K,Beck Y,Fukayama M,Kokudo N

更新日期：2009-06-01 00:00:00

abstract：:Plasminogen activator is a serine protease which exists in two forms, known as tissue-type plasminogen activator and urokinase-type plasminogen activator. Here, we show that urokinase-type plasminogen activator activity in primary breast carcinomas correlates with both size of tumor and number of axillary nodes with m...

journal_title：Cancer

authors： Duffy MJ,O'Grady P,Devaney D,O'Siorain L,Fennelly JJ,Lijnen HJ

更新日期：1988-08-01 00:00:00

abstract：BACKGROUND:Some vasoactive drugs have been studied in the hope of altering the vascular permeability and/or blood of tumors to enhance monoclonal antibody (MoAb) uptake. The pretreatment of interleukin-2 (IL-2), one of the vasoactive reagents, produced a generalized vascular permeability, but its function was not tumor...

journal_title：Cancer

authors： Nakamura K,Kubo A

更新日期：1997-12-15 00:00:00

abstract：:Human prostate specimens from 25 patients provided 15 normal, four benign prostatic hypertrophy (BPH), and seven adenocarcinoma samples which were studied using a polyclonal antibody against prostatic specific antigen (PSA) and protein A-gold complex. Our study showed the presence of gold particles in cytoplasmic vesi...

journal_title：Cancer

authors： Sinha AA,Wilson MJ,Gleason DF

更新日期：1987-09-15 00:00:00

abstract：:Image cytometry for the classification of fine needle aspirate (FNA) biopsies was evaluated in samples from 39 women. Eighteen of them had benign lesions, seven had premalignant lesions, nine had carcinoma in situ, and five had carcinoma. The term, premalignant, here refers to lesions with an increased risk of develop...

journal_title：Cancer

authors： King EB,Chew KL,Duarte L,Hom JD,Mayall BH,Miller TR,Petrakis NL

更新日期：1988-07-01 00:00:00

abstract：BACKGROUND:Acute myeloid leukemia (AML) with t(6;11)(q27;q23) is a well established but rare entity, and few studies have reported the full clinical, hematologic, and outcome data of patients with this disease. METHODS:To characterize the features of t(6;11) AML, the authors searched the Cancer and Leukemia Group B (C...

journal_title：Cancer

authors： Blum W,Mrózek K,Ruppert AS,Carroll AJ,Rao KW,Pettenati MJ,Anastasi J,Larson RA,Bloomfield CD

更新日期：2004-09-15 00:00:00

abstract：:Immunoproliferative small intestinal diseases (IPSID), previously known as Mediterranean Lymphomas, constitute more than 60% of the non-Burkitt's small intestinal lymphomas in Tunisia. A multidisciplinary study of IPSID was undertaken by the Tunisian/French Lymphoma Study Group in 1980 to reach a better understanding ...

journal_title：Cancer

authors： Tabbane F,Mourali N,Cammoun M,Najjar T

更新日期：1988-04-15 00:00:00

abstract：:The relation of gastric acid-secreting function to the gross and histological types and locations of carcinomas was examined in 53 patients with early gastric carcinomas. Studies were made by the endoscopic Congo red test developed in this clinic. Results indicated a close correlation between the gross and histologica...

journal_title：Cancer

authors： Tatsuta M,Okuda S,Taniguchi H,Tamura H

更新日期：1979-01-01 00:00:00

abstract：BACKGROUND:Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is the only treatment with a curative potential for myelodysplastic syndrome (MDS) patients. Allo-HSCT has substantial risks, particularly in the elderly, and its role for older MDS patients has yet to be defined. METHODS:We analyzed 88 MDS pati...

journal_title：Cancer

authors： Yucel OK,Saliba RM,Rondon G,Ahmed S,Alousi A,Bashir Q,Ciurea SO,Popat U,Khouri I,Marin D,Rezvani K,Kebriaei P,Shpall EJ,Champlin RE,Oran B

更新日期：2017-07-15 00:00:00

abstract：:A series of nine cases of radiation myelopathy seen at the University of California, San Francisco (UCSF) is reviewed, and their treatment data converted into nominal single doses (NSD) and equivalent single doses (ED). The 1% incidence level of myelopathy in the thoracic cord is 1015 rets (ED), and the 50% incidence...

journal_title：Cancer

authors： Wara WM,Phillips TL,Sheline GE,Schwade JG

更新日期：1975-06-01 00:00:00

abstract：BACKGROUND:Ordinary craniopharyngiomas affecting sellar regions of children and preadolescents are composed of ameloblastomatous and/or squamous constituents. The authors encountered an autopsy case of a stillborn infant with a large craniopharyngioma with unusual manifestations. METHODS:The craniopharyngioma was anal...

journal_title：Cancer

authors： Yamada H,Haratake J,Narasaki T,Oda T

更新日期：1995-06-15 00:00:00

abstract：BACKGROUND:Hospital services are expectantly reduced over the weekend, which may result in a delay in treatment or in obtainment of medical procedures. The authors investigated quality of care and clinical outcomes of newly diagnosed acute myeloid leukemia (AML) patients who were hospitalized on weekends versus weekday...

journal_title：Cancer

authors： Bejanyan N,Fu AZ,Lazaryan A,Fu R,Kalaycio M,Advani A,Sobecks R,Copelan E,Maciejewski JP,Sekeres MA

更新日期：2010-08-01 00:00:00

abstract：INTRODUCTION:The presence of nodal metastases remains the most significant predictive factor for regional recurrence and survival in patients treated for squamous cell carcinoma of the head and neck. Survival rates are further decreased in patients with nodal metastases that have spread beyond the lymph node capsule, o...

journal_title：Cancer

authors： Myers JN,Greenberg JS,Mo V,Roberts D

更新日期：2001-12-15 00:00:00

abstract：:Evaluation and radiotherapy implications of chest relapse patterns in small cell lung carcinoma treated with chemotherapy and radiotherapy to the chest and brain. Emphasis was placed on analysis of patterns of chest disease relapse, chest complications, and sites of initial chest disease relapse in relation to volume ...

journal_title：Cancer

authors： Mira JG,Livingston RB

更新日期：1980-12-15 00:00:00

abstract：BACKGROUND:The objective of the current study was to examine the impact of adherence to guidelines on stage-specific survival outcomes in patients with stage III and high-risk stage II colon cancer. The National Comprehensive Cancer Network (NCCN) has established working, expert consensus, and evidence-based guidelines...

journal_title：Cancer

authors： Boland GM,Chang GJ,Haynes AB,Chiang YJ,Chagpar R,Xing Y,Hu CY,Feig BW,You YN,Cormier JN

更新日期：2013-04-15 00:00:00

abstract：:In estrogen target tissues and hormone-dependent tumors, the steroid enters the cells and binds to a cytoplasmic protein called the estrogen receptor (ER). The steroid-receptor complex then migrates to the nuclei, where it initiates the biochemicial events characteristic of estrogen stimulation. Since ER is absent in ...

journal_title：Cancer

authors： McGuire WL

更新日期：1975-08-01 00:00:00

abstract：:The value of image analysis in predicting the malignant potential of oral epithelial lesions showing either hyperplasia or dysplasia was investigated; 5-micron formalin-fixed sections of 16 oral epithelial lesions, of which eight had later transformed to carcinoma and eight had not transformed during a follow-up of 10...

journal_title：Cancer

authors： Abdel-Salam M,Mayall BH,Chew K,Silverman S Jr,Greenspan JS

更新日期：1988-11-01 00:00:00

abstract：:Two cases of occult seminoma were observed which showed left-sided lymph node metastases without clinically demonstrable testicular tumors. The peculiar histology of the lymph node metastases, namely PAS-positive tumor cells with clear cytoplasm together with a granulomatous stromal reaction, was highly suggestive of ...

journal_title：Cancer

authors： Richter HJ,Leder LD

更新日期：1979-07-01 00:00:00

abstract：:Standardized incidence ratio for cancer in Norwegian Seventh-Day Adventists compared with the general population was not significantly different from unity (men 91, women 97). Persons converting late in life had a higher incidence than those converting at an earlier age. Respiratory cancers (standardized incidence rat...

journal_title：Cancer

authors： Fønnebø V,Helseth A

更新日期：1991-08-01 00:00:00