Alterations of peripheral blood B-lymphocyte populations in plasma cell disorders.

abstract：:Five hundred forty three adult patients with acute leukemia were entered on the study designed to: (1) test efficacy of vincristine and prednisone used as primary drug therapy in patients with good prognosis as judged by a circulating blast cell count less than 30,000 cm2; (2) investigate the use of either simultaneou...

journal_title：Cancer

authors： McCredie KB,Gehan EA,Freireich EJ,Hewlett JS,Coltman CA Jr,Hussein KK,Balcerzak SP,Chen TT

更新日期：1983-09-15 00:00:00

abstract：:Disease that is known to have extended beyond the prostatic capsule is unlikely to be cured by radical surgical excision, although the primary tumor may be controlled by external irradiation. The development of progressive (metastatic) disease is common and may be retarded by hormonal therapy. The timing of such treat...

journal_title：Cancer

authors： Smith PH

更新日期：1993-02-01 00:00:00

abstract：BACKGROUND:Controlled-release (CR) morphine tablets have become routine therapy in the management of cancer pain. Compared with immediate-release (IR) morphine, this formulation provides the benefit of dosing every 12 hours. METHODS:This study reviewed the 10 published, well controlled, repeated-dose, comparative stud...

journal_title：Cancer

authors： Warfield CA

更新日期：1998-06-15 00:00:00

abstract：BACKGROUND:The authors established the genotype frequencies of cytochrome P450 (CYP1A1/MspI, CYP2E1/PstI, and CYP2E1/DraI), glutathione-S-transferase (GSTM1 and GSTT1), and p53 (exon 4/AcclI and intron 3/16-base pair duplication) gene polymorphisms in cervical carcinoma patients and controls and evaluated the associati...

journal_title：Cancer

authors： Kim JW,Lee CG,Park YG,Kim KS,Kim IK,Sohn YW,Min HK,Lee JM,Namkoong SE

更新日期：2000-05-01 00:00:00

abstract：:Over the years, there has been a continuous increase in clinically relevant driver mutations in patients with non-small cell lung cancer (NSCLC). Among these, dysregulated activation of the MET tyrosine kinase receptor has gained importance due to the recent development of quite effective treatments. MET dysregulation...

journal_title：Cancer

authors： Friedlaender A,Drilon A,Banna GL,Peters S,Addeo A

更新日期：2020-11-15 00:00:00

abstract：BACKGROUND:Hepatocellular carcinoma (HCC) with portal venous invasion (PVI) has a very poor prognosis, with a median survival of 3 months and virtually no survival at 1 year. The combination of intraarterial 5-fluorouracil (FU) and systemic interferon-alpha (IFNalpha) was recently reported to be effective against HCC w...

journal_title：Cancer

authors： Obi S,Yoshida H,Toune R,Unuma T,Kanda M,Sato S,Tateishi R,Teratani T,Shiina S,Omata M

更新日期：2006-05-01 00:00:00

abstract：BACKGROUND:The use of docetaxel prolongs survival for patients with castrate-resistant prostate cancer (CRPC). Inhibition of vascular endothelial growth factor (VEGF) with bevacizumab may further enhance the antitumor effect of docetaxel and estramustine in patients with CRPC. METHODS:This cooperative group trial enro...

journal_title：Cancer

authors： Picus J,Halabi S,Kelly WK,Vogelzang NJ,Whang YE,Kaplan EB,Stadler WM,Small EJ,Cancer and Leukemia Group B.

更新日期：2011-02-01 00:00:00

abstract：BACKGROUND:Hepatectomy is the standard of care for patients with colorectal cancer who have isolated hepatic metastases; however, the long-term survival benefits of hepatectomy in this population have not been characterized well outside of case series. For the current study, a population-based database was used to comp...

journal_title：Cancer

authors： Cummings LC,Payes JD,Cooper GS

更新日期：2007-02-15 00:00:00

abstract：:The records of 52 patients younger than 40 years of age who had bronchogenic carcinoma diagnosed between 1965 and 1985 were reviewed. The preponderance of adenocarcinoma (54%), the lower male-female ratio in this age group compared with patients age 40 or older (2:1), the importance of cigarette smoking as a causative...

journal_title：Cancer

authors： Jubelirer SJ,Wilson RA

更新日期：1991-03-01 00:00:00

abstract：BACKGROUND:Patients affected by neurofibromatosis type 1 (NF1) are at higher risk of developing soft-tissue sarcomas (STS) than the general population. The clinical findings and outcome in 43 children and adolescents with NF1 treated for STS in the Italian protocols between 1988 and 2004 are reported. METHODS:The stud...

journal_title：Cancer

authors： Ferrari A,Bisogno G,Macaluso A,Casanova M,D'Angelo P,Pierani P,Zanetti I,Alaggio R,Cecchetto G,Carli M

更新日期：2007-04-01 00:00:00

abstract：BACKGROUND:Circulating prostate cells can be detected in the venous blood of patients with clinically localized prostate carcinoma by applying reverse transcriptase-polymerase chain reaction (RT-PCR) techniques using primers specific for the prostate specific antigen (PSA) gene. This study evaluates whether the detecti...

journal_title：Cancer

authors： Ennis RD,Katz AE,de Vries GM,Heitjan DF,O'Toole KM,Rubin M,Buttyan R,Benson MC,Schiff PB

更新日期：1997-06-15 00:00:00

abstract：BACKGROUND:Previous studies have shown that matrix metalloproteinase-2 (MMP-2) (a 72-kilodalton Type IV collagenase/gelatinase A) is associated with breast carcinoma, but to the authors' knowledge there are no reports showing that it is prognostic for overall survival. METHODS:Expression of the immunoreactive protein ...

journal_title：Cancer

authors： Talvensaari-Mattila A,Pääkkö P,Höyhtyä M,Blanco-Sequeiros G,Turpeenniemi-Hujanen T

更新日期：1998-09-15 00:00:00

abstract：BACKGROUND:In colorectal carcinoma, venous invasion has been related to patient survival. Liver metastasis develops more frequently when venous invasion is present. However, the histologic features and clinical significance of venous invasion are not well understood. METHODS:A histologic study of venous invasion in co...

journal_title：Cancer

authors： Ouchi K,Sugawara T,Ono H,Fujiya T,Kamiyama Y,Kakugawa Y,Mikuni J,Tateno H

更新日期：1996-12-01 00:00:00

abstract：:Proviral DNA of adult T-cell leukemia virus (HTLV-I) was examined by the standard Southern blotting method in lymph nodes of 45 patients with anti-HTLV-I antibody (ATLA)-positive adult T-cell leukemia/lymphoma (ATLL). Six of these patients revealed no monoclonal proviral HTLV-I DNA in tumor cells. These six patients s...

journal_title：Cancer

authors： Yoshida T,Kikuchi M,Ooshima K,Takeshita M,Kimura N,Kozuru M,Satoh H

更新日期：1989-12-15 00:00:00

abstract：:The evaluation of serial plasma carcinoembryonic antigen (CEA) levels is one of the most important parameter used to establish the prognosis of surgically cured colorectal cancer patients. Carcinoembryonic antigen is particularly useful in the identification of recurrences and metastasis. However, to improve the usefu...

journal_title：Cancer

authors： Midiri G,Amanti C,Benedetti M,Campisi C,Santeusanio G,Castagna G,Peronace L,Di Tondo U,Di Paola M,Pascal RR

更新日期：1985-06-01 00:00:00

abstract：LAY SUMMARY:Cancer has substantial economic impacts for patients, their families and/or caregivers, employers, and the health care system. However, there is only limited understanding of how economic issues can affect access to cancer care services and the receipt of high-quality cancer care. Health economics research ...

journal_title：Cancer

authors： Halpern MT,Shih YT,Yabroff KR,Ekwueme DU,Bradley CJ,Davidoff AJ,Sabik LM,Lipscomb J

更新日期：2020-11-25 00:00:00

abstract：BACKGROUND:To the authors' knowledge, the potential prognostic value of DNA ploidy in vulvar melanoma has not been evaluated in previous series. METHODS:Clinical data and follow-up information were retrieved from the hospital records of 75 patients treated from 1956 to 1987. Histopathologic specimens were reviewed for...

journal_title：Cancer

authors： Scheistrøen M,Tropé C,Koern J,Pettersen EO,Abeler VM,Kristensen GB

更新日期：1995-01-01 00:00:00

abstract：:During a 2-year period, three young Chinese women in Taiwan were found to have a rare pancreatic tumor known as solid and papillary neoplasm of the pancreas. They had a large abdominal mass, found either incidentally or because of abdominal discomfort. Endoscopic retrograde cholangiopancreatography was useful in local...

journal_title：Cancer

authors： Kuo TT,Su IJ,Chien CH

更新日期：1984-10-01 00:00:00

abstract：:Six patients with Hodgkin's disease (HD) and demonstrable serum antibodies to human immunodeficiency virus (HIV) and two additional patients with HD belonging to HIV-associated high-risk groups but with negative HIV serology were studied. All patients were men and ranged in age from 21 to 45 years. The HIV risk factor...

journal_title：Cancer

authors： Pelstring RJ,Zellmer RB,Sulak LE,Banks PM,Clare N

更新日期：1991-04-01 00:00:00

abstract：BACKGROUND:A series of retrospective studies have reported that patients with human epidermal growth factor receptor 2(HER2)-positive breast cancer are at a greater risk of central nervous system (CNS) metastases. Trastuzumab, which does not cross the blood-brain barrier, has been associated with this increased risk. ...

journal_title：Cancer

authors： Musolino A,Ciccolallo L,Panebianco M,Fontana E,Zanoni D,Bozzetti C,Michiara M,Silini EM,Ardizzoni A

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND:Stereotactic radiation therapy is highly effective in the treatment of small brain metastases, regardless of the histology. This suggests that small extracranial malignancies may be curable with similar radiation therapy. The authors developed a novel treatment unit for administering such therapy. METHODS:T...

journal_title：Cancer

authors： Uematsu M,Shioda A,Tahara K,Fukui T,Yamamoto F,Tsumatori G,Ozeki Y,Aoki T,Watanabe M,Kusano S

更新日期：1998-03-15 00:00:00

abstract：BACKGROUND:The purpose of this study was to compare outcomes in patients with anal canal squamous cell carcinoma (SCCA) who were treated with definitive chemoradiotherapy by either intensity-modulated radiation therapy (IMRT) or conventional radiotherapy (CRT). METHODS:Forty-six patients who received definitive chemor...

journal_title：Cancer

authors： Bazan JG,Hara W,Hsu A,Kunz PA,Ford J,Fisher GA,Welton ML,Shelton A,Kapp DS,Koong AC,Goodman KA,Chang DT

更新日期：2011-08-01 00:00:00

abstract：BACKGROUND:Inflammatory breast cancer (IBC) is a rare but aggressive form of breast cancer. Despite multimodality treatment, the long-term survival rate for patients with IBC has remained inferior at 50%. Until recently, IBC was understudied at the molecular level. Since 2004, new high-throughput molecular profiling te...

journal_title：Cancer

authors： Bertucci F,Finetti P,Birnbaum D,Viens P

更新日期：2010-06-01 00:00:00

abstract：BACKGROUND:Lesions of the thyroid gland composed of Hurthle cells encompass pathologic entities ranging from hyperplastic nodules with Hurthle cell metaplasia to Hurthle cell carcinomas. The cytologic distinction between these entities can be diagnostically challenging. Many cytologic features of Hurthle cell lesions t...

journal_title：Cancer

authors： Elliott DD,Pitman MB,Bloom L,Faquin WC

更新日期：2006-04-25 00:00:00

abstract：:This article describes two patients with hepatic metastases from colorectal cancer in whom a reversible enteropathy developed during the administration of hepatic artery infusion chemotherapy with 5-fluoro-2-deoxyuridine (5-FUdR) via an Infusaid Series 400 pump (Infusaid Corp., Sharon, MA). Both patients had severe di...

journal_title：Cancer

authors： Gluck WL,Akwari OE,Kelvin FM,Goodwin BJ

更新日期：1985-11-15 00:00:00

abstract：:Necropsy and clinical data show that primary hepatocellular carcinoma (PHC) is the commonest cancer among the Senoi (a Malaysian aboringine group). The other aboringine tribes do not appear to have this high predilection for liver cancer. In the necropsy series, PHS was present in 10 out of 22 Senoi patients with cirr...

journal_title：Cancer

authors： Sumithran E,Prathap K

更新日期：1977-10-01 00:00:00

abstract：BACKGROUND:Lysosomal proteases are implicated in cancer progression and metastasis. In the current study, using subtraction cloning for genes that are differentially expressed in metastasis, the authors isolated a clone encoding ceroid lipofuscinosis, neuronal 2 (CLN2), which is a lysosomal serine protease defective in...

journal_title：Cancer

authors： Tsukamoto T,Iida J,Dobashi Y,Furukawa T,Konishi F

更新日期：2006-04-01 00:00:00

abstract：:The cancer experience among 754 first-degree relatives (mothers, fathers, and siblings) of a population-based series of 177 children with soft tissue sarcoma is reported. The current study represents an extension of our earlier work in which the authors found an excess of breast cancer in the mothers of 143 of these c...

journal_title：Cancer

authors： Birch JM,Hartley AL,Blair V,Kelsey AM,Harris M,Teare MD,Jones PH

更新日期：1990-11-15 00:00:00

abstract：BACKGROUND:Breast carcinoma is one of the leading causes of excess mortality rates in Harlem, an inner-city neighborhood with the highest mortality rates and worst life expectancy in New York City. This study reports the results of a breast carcinoma screening and diagnostic program in Harlem. METHODS:Retrospective re...

journal_title：Cancer

authors： Liberman L,Freeman HP,Chandra S,Stein AL,McCord C,Godfrey D,Dershaw DD

更新日期：2002-07-01 00:00:00

abstract：:Twenty-three bilateral testicular germ cell tumors (four synchronous and 19 sequential tumors) were investigated for potential risk factors. The incidence of maldescensus testis was not found to be higher than in patients with unilateral disease. The histologic findings of the first tumor did not have any effect on th...

journal_title：Cancer

authors： Kratzik C,Aiginger P,Kuber W,Riccabona M,Kührer I,Joos H,Frick J,Amann G,Mayr W

更新日期：1991-08-15 00:00:00