A reversible enteropathy complicating continuous hepatic artery infusion chemotherapy with 5-fluoro-2-deoxyuridine.

abstract：BACKGROUND:In the phase 3 MARIANNE trial, trastuzumab emtansine (T-DM1) with or without pertuzumab showed noninferior progression-free survival and better tolerability than trastuzumab plus a taxane (HT) for the first-line treatment of human epidermal growth factor receptor 2 (HER2)-positive advanced breast cancer. Thi...

journal_title：Cancer

authors： Perez EA,Barrios C,Eiermann W,Toi M,Im YH,Conte P,Martin M,Pienkowski T,Pivot XB,Burris HA 3rd,Petersen JA,De Haas S,Hoersch S,Patre M,Ellis PA

更新日期：2019-11-15 00:00:00

abstract：:This study compared the resting energy expenditure (REE) modifications observed during successive intensive identical chemotherapy courses in non-Hodgkin's lymphoma patients to assess indirectly the metabolic changes induced by the cytotoxic effect of drugs on the tumor. With this therapeutic regimen, reduction of tum...

journal_title：Cancer

authors： Delarue J,Lerebours E,Tilly H,Rimbert A,Hochain P,Guedon C,Piguet H,Colin R

更新日期：1990-06-01 00:00:00

abstract：:The assumption that asymptomatic colorectal cancers bleed provides the rationale for widespread stool screening. The authors studied 12 patients with unoperated colorectal cancer but without colorectal symptoms and six healthy volunteers as laboratory controls. All stools were collected for 2 weeks and analyzed by the...

journal_title：Cancer

authors： Ahlquist DA,McGill DB,Fleming JL,Schwartz S,Wieand HS,Rubin J,Moertel CG

更新日期：1989-05-01 00:00:00

abstract：:The clinical presentation of the disease and the results of treatment in 42 patients with malignant peripheral neuroectodermal tumors (MPNT) entered into the Cooperative Ewing's, soft tissue, and neuroblastoma trials of the German Society of Pediatric Oncology were retrospectively analyzed. Within the Ewing's sarcoma ...

journal_title：Cancer

authors： Jürgens H,Bier V,Harms D,Beck J,Brandeis W,Etspüler G,Gadner H,Schmidt D,Treuner J,Winkler K

更新日期：1988-01-15 00:00:00

abstract：:Ninety-two cases of granulosa cell tumor of the ovary have been studied. The clinical and pathologic data from this group were similar to that obtained in previous series. Because of the long natural history of many granulosa cell tumors, crude death rates over a relatively short period give little indication of the t...

journal_title：Cancer

authors： Fox H,Agrawal K,Langley FA

更新日期：1975-01-01 00:00:00

abstract：:In this study of 454 colorectal carcinoma colectomy specimens, (289 were associated with and 165 were unassociated with schistosomiasis. Schistosome infestation was found to play an etiologic role in bowel malignancy in patients having diffuse involvement of the large intestine and a history of ten years or more of co...

journal_title：Cancer

authors： Ming-Chai C,Chi-Yuan C,Pei-Yu C,Jen-Chun H

更新日期：1980-10-01 00:00:00

abstract：BACKGROUND:Carboplatin-based regimens have demonstrated activity in pediatric patients with low-grade glioma (LGG). However, carboplatin hypersensitivity reaction (Cb HSR) represents a common and limiting factor for the continuation of therapy. METHODS:The objectives of this study were to describe the prevalence, char...

journal_title：Cancer

authors： Lafay-Cousin L,Sung L,Carret AS,Hukin J,Wilson B,Johnston DL,Zelcer S,Silva M,Odame I,Mpofu C,Strother D,Bouffet E

更新日期：2008-02-15 00:00:00

abstract：:A hospital-based case-control study was done to examine the hypothesis that persons with a family history of multiple myeloma (MM) or other cancers are at increased risk of multiple myeloma. Study members were 439 cases of multiple myeloma and 1317 matched controls seen at the Duke University Medical Center. Only 3 ca...

journal_title：Cancer

authors： Bourguet CC,Grufferman S,Delzell E,DeLong ER,Cohen HJ

更新日期：1985-10-15 00:00:00

abstract：BACKGROUND:Information regarding prognostic factors and survival in elderly women with metastatic breast cancer treated with tamoxifen is limited. METHODS:The data from 4 prospective clinical trials were analyzed, including information on 396 postmenopausal women with advanced breast cancer who received tamoxifen as i...

journal_title：Cancer

authors： Dhodapkar MV,Ingle JN,Cha SS,Mailliard JA,Wieand HS

更新日期：1996-02-15 00:00:00

abstract：:Plasma carcinoembryonic antigen (CEA) levels were studied in all available members of 17 families in which a presumed sporadic retinoblastoma had occurred. In 9 of the 17 families, close relatives of the patient had elevated CEA levels in the absence of demonstrable disease; this we have termed the "CEA family syndrom...

journal_title：Cancer

authors： Felberg NT,Michelson JB,Shields JA

更新日期：1976-03-01 00:00:00

abstract：:Lobular carcinoma in situ (LCIS) has uncertain malignant potential; biologic markers that will identify patients at risk for a poor clinical outcome have been sought actively. Amplification of the c-erbB-2 protooncogene has been correlated with poor prognosis in invasive mammary carcinoma, and immunohistochemical eval...

journal_title：Cancer

authors： Porter PL,Garcia R,Moe R,Corwin DJ,Gown AM

更新日期：1991-07-15 00:00:00

abstract：:The reported results from throughout the world of modern treatment of testicular seminoma are reviewed for the various clinical stages of disease. The three-year survival rate for 1,346 patients with Stage 1 and 2 disease is 91%. Since the review reveals considerable differences in staging methods, a clinically useful...

journal_title：Cancer

authors： Caldwell WL,Kademian MT,Frias Z,Davis TE

更新日期：1980-04-01 00:00:00

abstract：BACKGROUND:Aggressive non-Hodgkin's lymphoma is now often curable with chemotherapy. The International Prognostic Index (IPI) was recently developed to predict patient survival on the basis of pretreatment clinical features. However, classical multivariate regression models such as the IPI fail to detect time-dependent...

journal_title：Cancer

authors： Mounier N,Morel P,Haioun C,Coiffier B,Tilly H,Chatelain C,Lederlin P,Thyss A,Herbrecht R,Gisselbrecht C,Lepage E

更新日期：1998-05-15 00:00:00

abstract：:The authors administered high-dose chemotherapy with cyclophosphamide, BCNU (carmustine) and VP-16 (etoposide) plus autologous bone marrow transplantation (ABMT) to 22 adult patients with relapsed acute leukemia in second or subsequent remission. The marrow was not treated ex vivo. The long-term, disease-free survival...

journal_title：Cancer

authors： Spinolo JA,Dicke KA,Horwitz LJ,Jagannath S,McCredie K,Estey E,Kantarjian H,Zander AR,Keating M,Spitzer G

更新日期：1990-08-15 00:00:00

abstract：:Renal cell carcinoma (RCC) evokes an immune response, which occasionally has resulted in spontaneous and dramatic remissions. In an attempt to reproduce or accentuate this response, various immunotherapeutic strategies have been studied. The most consistent antitumor activity has been reported with interferon-alpha (I...

journal_title：Cancer

authors： McDermott DF

更新日期：2009-05-15 00:00:00

abstract：:Categories of objective response to chemotherapy for 460 advanced relapsing prostate cancer patients evaluated in the initial first four randomized clinical trials of the National Prostatic Cancer Project were compared by survival and other patient and disease characteristics. The response criteria for stable were sho...

journal_title：Cancer

authors： Slack NH,Mittelman A,Brady MF,Murphy GP

更新日期：1980-12-01 00:00:00

abstract：:In Finland, the incidence of cervical cancer has shown a decreasing tendency since the 1960s. The same trend, however, has not been noticed in the incidence of cervical adenocarcinoma. The reason for this is not known, although many studies have shown differences in the cause, epidemiology, and biology of the epidermo...

journal_title：Cancer

authors： Leminen A,Paavonen J,Forss M,Wahlström T,Vesterinen E

更新日期：1990-01-01 00:00:00

abstract：BACKGROUND:The current study was performed to determine whether neuropsychologic functioning differs in breast cancer survivors 6 months after the completion of adjuvant treatment compared with women without cancer. METHODS:Participants were 187 women who were diagnosed with ductal carcinoma in situ or stage I or stag...

journal_title：Cancer

authors： Jim HS,Donovan KA,Small BJ,Andrykowski MA,Munster PN,Jacobsen PB

更新日期：2009-04-15 00:00:00

abstract：:Forty-nine patients with regionally confined recurrent malignancy were treated with intra-arterial cis-diamminedichloro platinum II in a Phase I-II trial. A safe starting dose of 120 mg/m2 was established. An overall response rate of 45% was noted with significant responses observed among patients with melanoma, sarco...

journal_title：Cancer

authors： Calvo DB 3rd,Patt YZ,Wallace S,Chuang VP,Benjamin RS,Pritchard JD,Hersh EM,Bodey GP Sr,Mavligit GM

更新日期：1980-03-15 00:00:00

abstract：BACKGROUND:Attrition is common among supportive care/palliative oncology clinical trials. However, to the authors' knowledge, few studies to date have documented the reasons and predictors for dropout. In the current study, the authors' objective was to determine the rate, reasons, and factors associated with attrition...

journal_title：Cancer

authors： Hui D,Glitza I,Chisholm G,Yennu S,Bruera E

更新日期：2013-03-01 00:00:00

abstract：:A retrospective study was done of all patients who were seen for definitive treatment of adenocarcinoma of the pancreas at the Massachusetts General Hospital from 1963 to 1973. There were a total of 145 patients. Thirty-one patients were treated with radical surgery, with a 16% operative mortality, a 5-year crude surv...

journal_title：Cancer

authors： Tepper J,Nardi G,Sutt H

更新日期：1976-03-01 00:00:00

abstract：BACKGROUND:A series of retrospective studies have reported that patients with human epidermal growth factor receptor 2(HER2)-positive breast cancer are at a greater risk of central nervous system (CNS) metastases. Trastuzumab, which does not cross the blood-brain barrier, has been associated with this increased risk. ...

journal_title：Cancer

authors： Musolino A,Ciccolallo L,Panebianco M,Fontana E,Zanoni D,Bozzetti C,Michiara M,Silini EM,Ardizzoni A

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND:There are few reports comparing the clinicopathologic features of sarcomas of the aorta (SA), sarcomas of the inferior vena cava (SIVC), and sarcomas of the pulmonary artery (SPA). METHODS:The authors retrospectively reviewed 11 SA, 16 SIVC, and 16 SPA, and compared clinical, pathologic, and immunohistochem...

journal_title：Cancer

authors： Burke AP,Virmani R

更新日期：1993-03-01 00:00:00

abstract：BACKGROUND:Ideally, screening detects cancer at a more curable stage and, as a result, decreases the rate of subsequent diagnosis at a late stage. Although it is suggested that some cancer screening tests have led to substantial increases in early-stage incidence with only marginal reductions in late-stage incidence (e...

journal_title：Cancer

authors： Yang DX,Gross CP,Soulos PR,Yu JB

更新日期：2014-09-15 00:00:00

abstract：:To evaluate the incidence of thrombocytopenia and bleeding among patients with solid tumors treated intensively with chemotherapy, the records of 1274 patients treated between 1972 and 1980 on protocols known to produce significant myelosuppression were reviewed. Three hundred one patients with solid tumors (breast, l...

journal_title：Cancer

authors： Dutcher JP,Schiffer CA,Aisner J,O'Connell BA,Levy C,Kendall JA,Wiernik PH

更新日期：1984-02-01 00:00:00

abstract：:The evaluation of serial plasma carcinoembryonic antigen (CEA) levels is one of the most important parameter used to establish the prognosis of surgically cured colorectal cancer patients. Carcinoembryonic antigen is particularly useful in the identification of recurrences and metastasis. However, to improve the usefu...

journal_title：Cancer

authors： Midiri G,Amanti C,Benedetti M,Campisi C,Santeusanio G,Castagna G,Peronace L,Di Tondo U,Di Paola M,Pascal RR

更新日期：1985-06-01 00:00:00

abstract：BACKGROUND:Radiologic Diagnostic Oncology Group 5 is a multicenter clinical trial designed to evaluate fine-needle aspiration (FNA) of nonpalpable breast lesions performed by multiple operators using the same protocol. METHODS:Four hundred and nineteen women with mammographically detected nonpalpable breast lesions we...

journal_title：Cancer

authors： Pisano ED,Fajardo LL,Tsimikas J,Sneige N,Frable WJ,Gatsonis CA,Evans WP,Tocino I,McNeil BJ

更新日期：1998-02-15 00:00:00

abstract：:The authors retrospectively searched for human papillomavirus (HPV) types 16 and 18 in 60 cases of carcinoma arising from the nasal cavities (NC) and paranasal sinuses (PS) by using the polymerase chain reaction (PCR) on DNA extracted from formalin-fixed, paraffin-embedded tissues. In cases of SCC (n = 49), the author...

journal_title：Cancer

authors： Furuta Y,Takasu T,Asai T,Shinohara T,Sawa H,Nagashima K,Inuyama Y

更新日期：1992-01-15 00:00:00

abstract：BACKGROUND:Patients who travel a long distance (≥50 miles) for cancer care have improved outcomes. However, to the authors' knowledge, the prevalence of long travel distances for treatment by patients with head and neck squamous cell carcinoma (HNSCC), and the effect of travel distance on overall survival (OS), remains...

journal_title：Cancer

authors： Graboyes EM,Ellis MA,Li H,Kaczmar JM,Sharma AK,Lentsch EJ,Day TA,Hughes Halbert C

更新日期：2018-08-01 00:00:00

abstract：:A classification for childhood brain tumors based upon revision of nomenclature of all brain tumors published by the World Health Organization (WHO) in 1979 is proposed. Applicability of the WHO classification scheme was tested in a combined study of the clinical and pathologic features of approximately 3300 brain tum...

journal_title：Cancer

authors： Rorke LB,Gilles FH,Davis RL,Becker LE

更新日期：1985-10-01 00:00:00