High-dose chemotherapy and unpurged autologous bone marrow transplantation for acute leukemia in second or subsequent remission.

abstract：:The diagnosis of pulmonary candidiasis can only be made with certainty when tissue invasion by the organism is demonstrated histologically. In order to ascertain whether characteristic radiographic patterns are seen in patients with pulmonary candidiasis, antemortem radiographic abnormalities were correlated with auto...

journal_title：Cancer

authors： Dubois PJ,Myerowitz RL,Allen CM

更新日期：1977-09-01 00:00:00

abstract：:A 58-year-old patient with metastatic prostatic carcinoma had two well-documented episodes of disseminated intravascular coagulation (DIC) occurring 1 year apart and resolving without heparin therapy. This case illustrates that DIC need not have a poor prognosis and may resolve spontaneously despite progressive cancer...

journal_title：Cancer

authors： Alving BM,Abeloff MD,Bell W

更新日期：1976-02-01 00:00:00

abstract：BACKGROUND:This study was conducted to determine the efficacy and safety of irinotecan (CPT-11) as second-line therapy in patients with advanced cervical carcinoma. METHODS:Sixteen patients with platinum-resistant squamous cell carcinoma were treated with CPT-11 as second-line therapy. CPT-11 was administered in repea...

journal_title：Cancer

authors： Irvin WP,Price FV,Bailey H,Gelder M,Rosenbluth R,Durivage HJ,Potkul RK

更新日期：1998-01-15 00:00:00

abstract：BACKGROUND:The current study was performed to create a scoring system to estimate the survival of patients with metastatic spinal cord compression (MSCC). METHODS:Based on a multivariate survival analysis of 1852 patients who were treated with radiotherapy (RT) for MSCC, a scoring system was developed. The system incl...

journal_title：Cancer

authors： Rades D,Dunst J,Schild SE

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:It has previously been shown that heparanase-1 (HPR1), an endoglycosidase, is up-regulated in pancreatic carcinoma. The purpose of this study was to test whether serum HPR1 levels in pancreatic carcinoma patients are elevated, and whether higher serum HPR1 levels are associated with a shortened survival. ME...

journal_title：Cancer

authors： Quiros RM,Rao G,Plate J,Harris JE,Brunn GJ,Platt JL,Gattuso P,Prinz RA,Xu X

更新日期：2006-02-01 00:00:00

abstract：BACKGROUND:Patients with aggressive non-Hodgkin lymphoma (NHL) require intensive and extensive therapy, which seems impracticable in elderly patients due to hematologic and extrahematologic toxicity. Consequent dose reduction and therapy attenuation can reduce treatment-related toxicity but also decreases therapeutic e...

journal_title：Cancer

authors： Rigacci L,Carpaneto A,Alterini R,Carrai V,Bernardi F,Bellesi G,Longo G,Bosi A,Rossi Ferrini P

更新日期：2003-01-01 00:00:00

abstract：:The authors present the case of a 40-year-old white man with an obstructing laryngeal mass. Despite considerable tumor size, results of repeated biopsies revealed widespread carcinoma in situ with chronic inflammation within the subcutaneous tissues, and only after extensive endoscopic "debulking" of the mass was a sm...

journal_title：Cancer

authors： Eskinazi DP,Mihail R,Dichtel WG

更新日期：1985-08-01 00:00:00

abstract：:There is justifiable excitement about the recent introduction of prophylactic vaccines against human papillomavirus (HPV) types 16 (HPV-16) and HPV-18. Preventing these infections theoretically could avert approximately 70% of cervical cancer cases worldwide. In the U.S., numerous influential advocates are calling for...

journal_title：Cancer

authors： Schiffman M

更新日期：2007-06-25 00:00:00

abstract：BACKGROUND:Race is associated with patterns of presentation and survival outcomes of gastric cancer in the United States. However, the impact of race on the receipt of guideline-recommended care is not well characterized. By using current recommendations, the authors examined the association between race and guideline-...

journal_title：Cancer

authors： Al-Refaie WB,Gay G,Virnig BA,Tseng JF,Stewart A,Vickers SM,Tuttle TM,Feig BW

更新日期：2010-01-15 00:00:00

abstract：:The autopsies of 80 patients with Hodgkin's disease (HD) were reviewed. Nearly one-third of the patients died without evidence of HD at autopsy. Four patients died with clinically unsuspected HD. Infection was the most common cause of death but a significant number of patients died of complications of therapy, both be...

journal_title：Cancer

authors： Colby TV,Hoppe RT,Warnke RA

更新日期：1981-04-01 00:00:00

abstract：BACKGROUND:Response rates in chronic myeloid leukemia (CML) are now reported based on the cumulative incidence of a single-time best response. The study aim was to examine the significance of different response criteria for CML on imatinib therapy. METHODS:In all, 276 patients with chronic phase CML on imatinib therap...

journal_title：Cancer

authors： Kantarjian H,O'Brien S,Shan J,Huang X,Garcia-Manero G,Faderl S,Ravandi-Kashani F,Verstovsek S,Beth Rios M,Cortes J

更新日期：2008-02-15 00:00:00

abstract：BACKGROUND:Acquired Glanzmann's thrombasthenia is a rare hemorrhagic diathesis resulting from impaired adhesive function of the platelet receptor GPIIb/IIIa (alpha(IIb)beta3). Typically, this disorder develops during adulthood, with patients manifesting fluctuating clinical and laboratory findings. To date, the underly...

journal_title：Cancer

authors： Malik U,Dutcher JP,Oleksowicz L

更新日期：1998-05-01 00:00:00

abstract：:An unusual case of myeloproliferative disorder in which mature and immature myeloid cells were found to contain unusual cytoplasmic inclusions is reported. By light microscopy, these inclusions could be observed with Wright's stain. By electron microscopy they appeared to consist of a pale, finely granular material wi...

journal_title：Cancer

authors： Coppola A,O'Connor J

更新日期：1977-11-01 00:00:00

abstract：BACKGROUND:It has been reported that MUC1 is an important prognostic factor in several cancers. This study investigated the importance of MUC1 as a prognostic factor in mass-forming intrahepatic cholangiocarcinoma (m-ICC). METHODS:In 50 patients with m-ICC who had undergone hepatectomy, expression of MUC1 was investig...

journal_title：Cancer

authors： Matsumura N,Yamamoto M,Aruga A,Takasaki K,Nakano M

更新日期：2002-03-15 00:00:00

abstract：BACKGROUND:The Akt/mammalian target of rapamycin (mTOR) pathway mediates cell survival and proliferation and contributes to tumor progression. Soft tissue leiomyosarcoma continues to show poor prognosis, and little is known about its mechanisms of tumor progression. Here the authors investigated the significance of act...

journal_title：Cancer

authors： Setsu N,Yamamoto H,Kohashi K,Endo M,Matsuda S,Yokoyama R,Nishiyama K,Iwamoto Y,Dobashi Y,Oda Y

更新日期：2012-03-15 00:00:00

abstract：BACKGROUND:Immunohistological markers specific for a single type of epithelium are rare. Recently, urothelium tissue-specific genes were cloned. The genes encoded a family of transmembrane proteins, uroplakins, that are expressed only in urothelial mucosa. Using uroplakin antibodies on paraffin-embedded tissue, a previ...

journal_title：Cancer

authors： Xu X,Sun TT,Gupta PK,Zhang P,Nasuti JF

更新日期：2001-06-25 00:00:00

abstract：BACKGROUND:Patients with metachronous multiple colorectal carcinomas have been reported to have a higher frequency of a family history of colorectal carcinoma, associated colorectal adenomas, and extracolonic malignancies. These clinicopathologic factors also are considered to be related to the development of metachron...

journal_title：Cancer

authors： Masubuchi S,Konishi F,Togashi K,Okamoto T,Senba S,Shitoh K,Kashiwagi H,Kanazawa K,Tsukamoto T

更新日期：1999-05-01 00:00:00

abstract：BACKGROUND:Little is known about genetic aberrations associated with development and progression of biliary tract carcinomas. METHODS:To study chromosomal aberrations associated with development and progression of biliary tract carcinomas, the authors used comparative genomic hybridization to examine 50 such carcinoma...

journal_title：Cancer

authors： Shiraishi K,Okita K,Harada T,Kusano N,Furui T,Kondoh S,Oga A,Kawauchi S,Fukumoto Y,Sasaki K

更新日期：2001-02-01 00:00:00

abstract：BACKGROUND:Fine-needle aspiration biopsy (FNAB) is a reliable, rapid, minimally invasive alternative to surgical biopsy when it is performed by physician specialists for the diagnosis of palpable masses. FNAB may be under-utilized in community hospitals in the U.S. because physicians without specialty training commonly...

journal_title：Cancer

authors： Florentine BD,Staymates B,Rabadi M,Barstis J,Black A,Cancer Committee of the Henry Mayo Newhall Memorial Hospital.

更新日期：2006-07-15 00:00:00

abstract：BACKGROUND:Outcomes for patients with relapsed/refractory acute myeloid leukemia (R/R AML) remain poor. Novel therapies specifically targeting AML are of high interest. Brentuximab vedotin (BV) is an antibody-drug conjugate that is specific for human CD30. In this phase 1 dose escalation study, the authors evaluated th...

journal_title：Cancer

authors： Narayan R,Blonquist TM,Emadi A,Hasserjian RP,Burke M,Lescinskas C,Neuberg DS,Brunner AM,Hobbs G,Hock H,McAfee SL,Chen YB,Attar E,Graubert TA,Bertoli C,Moran JA,Bergeron MK,Foster JE,Ramos AY,Som TT,Vartanian MK,

更新日期：2020-03-15 00:00:00

abstract：BACKGROUND:The Danish Breast Cancer Cooperative Group (DBCG) 77B trial examined the relative efficacy of levamisole, single-agent oral cyclophosphamide, and the classic combination of cyclophosphamide, methotrexate, and 5-fluorouracil (CMF) against no adjuvant systemic therapy in high-risk breast cancer patients. The a...

journal_title：Cancer

authors： Ejlertsen B,Mouridsen HT,Jensen MB,Andersen J,Andersson M,Kamby C,Knoop AS,Danish Breast Cancer Cooperative Group.

更新日期：2010-05-01 00:00:00

abstract：BACKGROUND:Although the anticancer effects of progesterone therapy for patients with endometrial carcinoma are widely acknowledged, a detailed assessment of the resultant morphologic alterations in tumor tissue kinetics has hitherto been lacking. METHODS:Biopsy and hysterectomy specimens of 14 endometrial carcinomas (...

journal_title：Cancer

authors： Saegusa M,Okayasu I

更新日期：1998-07-01 00:00:00

abstract：BACKGROUND:Treatment of febrile neutropenia (FN) is costly, because it typically involves hospitalization. As cancer rates continue to increase, the number of patients suffering from FN will also increase, making it important to quantify the costs of treating this condition accurately and comprehensively. METHODS:A co...

journal_title：Cancer

authors： Lathia N,Mittmann N,DeAngelis C,Knowles S,Cheung M,Piliotis E,Shear N,Walker S

更新日期：2010-02-01 00:00:00

abstract：:The incidence of ovarian cancer in Rochester, Minnesota over the 40-year period 1935 through 1974 was determined; and risk factors for epithelial ovarian cancer occurring in Rochester from 1945 to 1974 were examined in 116 patients and 464 controls. Among the characteristics studied, only nulliparity was found to be a...

journal_title：Cancer

authors： Annegers JF,Strom H,Decker DG,Dockerty MB,O'Fallon WM

更新日期：1979-02-01 00:00:00

abstract：BACKGROUND:The purpose of this study was to present planning, feasibility, toxicity, and outcome of helical tomotherapy for spinal cord-sparing reirradiation of spinal metastases and tumors. METHODS:Thirty-six patients with spinal metastases and tumors who had undergone previous radiotherapy were reirradiated with hel...

journal_title：Cancer

authors： Sterzing F,Hauswald H,Uhl M,Herm H,Wiener A,Herfarth K,Debus J,Krempien R

更新日期：2010-08-15 00:00:00

abstract：:Fifty-one patients with confirmed bladder cancer have enrolled in a prospective evaluation of BCG immunotherapy. Following resection of existing tumors, patients were stratified according to tumor grade and number of previous recurrences and randomly assigned to control or BCG treatment groups. Immunotherapy consisted...

journal_title：Cancer

authors： Lamm DL,Thor DE,Winters WD,Stogdill VD,Radwin HM

更新日期：1981-07-01 00:00:00

abstract：BACKGROUND:To clarify the differences in angiogenesis between benign and malignant ovarian tumors, the authors examined the immunohistochemical characteristics and the density of tumor vessels in both tumor groups. Intratumoral vascularization was observed preoperatively by transvaginal color Doppler ultrasound. METHO...

journal_title：Cancer

authors： Emoto M,Iwasaki H,Mimura K,Kawarabayashi T,Kikuchi M

更新日期：1997-09-01 00:00:00

abstract：:The hematologic factors of 16 female patients with breast carcinoma who had received adjuvant chemotherapy with L-phenylalanine-based programs for two years were compared with those for 13 normal female volunteers of similar age. The findings include significant suppression of the mean hemoglobin level, of leukocyte c...

journal_title：Cancer

authors： Corder MP,Jochimsen PR

更新日期：1982-06-15 00:00:00

abstract：:Many cancer patients have elevated serum protein and sialic acid (N-acetyl neuraminic acid, NANA) levels. Serial determinations were performed, using serum treated with perchloric acid from 34 patients with widespread metastatic disease. Six of six patients who underwent debulking surgery had a drop in their serum NAN...

journal_title：Cancer

authors： Harvey HA,Lipton A,White D,Davidson E

更新日期：1981-01-15 00:00:00

abstract：BACKGROUND:The presence of tumor cells in peritoneal washing cytology specimens taken during surgery affects the staging of many gynecologic malignancies. Peritoneal washings are often collected routinely, even in cases of presumed benign disease. This study was designed to address whether evaluation of these specimens...

journal_title：Cancer

authors： Sharifi S,Ducatman BS,Wang HH,Fraser JL

更新日期：1999-10-25 00:00:00