Variations in gastric cancer care: a trend beyond racial disparities.

Abstract:

BACKGROUND:Race is associated with patterns of presentation and survival outcomes of gastric cancer in the United States. However, the impact of race on the receipt of guideline-recommended care is not well characterized. By using current recommendations, the authors examined the association between race and guideline-recommended treatments and identified factors that are predictive of variations in gastric cancer care. METHODS:By using the National Cancer Database for 1998 through 2005, 106,002 patients with gastric adenocarcinoma were identified. Multivariate analysis techniques were used to examine the association between race, the receipt of guideline-recommended care, and survival after adjusting for covariates. RESULTS:Although African-American and Hispanic patients were more likely to undergo adequate lymphadenectomy (> or =15 lymph nodes) and to receive care at comprehensive cancer centers and high-volume facilities (for all, P < or = .001), they were less likely to receive adjuvant multimodality therapy for American Joint Committee on Cancer stage IB through IV, lymph node-negative (M0) disease. Up to 60% of all patients who underwent gastrectomy failed to receive adequate lymphadenectomy and adjuvant multimodality therapy. The delivery of multimodality therapy varied significantly by stage and lymph node evaluation (P < or = .001). These findings persisted on our multivariate analyses, indicating that African-American and Hispanic patients received adequate lymph node evaluation (P < or = .001), whereas they were associated with receiving no adjuvant multimodality therapy (P < or = .025). CONCLUSIONS:There were significant variations in treatment for gastric cancer among ethnic groups in the United States. It was noteworthy that, although nonwhite race was associated with improved surgical care, gastric cancer care remained suboptimal overall. Cancer programs need to identify procedures to maximize the delivery of adequate gastric cancer care to all patients.

journal_name

Cancer

journal_title

Cancer

authors

Al-Refaie WB,Gay G,Virnig BA,Tseng JF,Stewart A,Vickers SM,Tuttle TM,Feig BW

doi

10.1002/cncr.24772

subject

Has Abstract

pub_date

2010-01-15 00:00:00

pages

465-75

issue

2

eissn

0008-543X

issn

1097-0142

journal_volume

116

pub_type

杂志文章

相关文献

CANCER文献大全
  • Diagnosis of orbital tumors by aspiration biopsy guided by computerized tomography.

    abstract::Thin-needle aspiration biopsy (TNAB) was performed on 22 patients with orbital tumors. Nine patients were studied before the introduction of computed tomography (CT) and only two cytologic diagnoses could be established. Thirteen aspiration biopsies guided by CT were successful. The technique of the CT-guided TNAB of ...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19841201)54:11<2385::aid-cncr282

    authors: Czerniak B,Woyke S,Daniel B,Krzysztolik Z,Koss LG

    更新日期:1984-12-01 00:00:00

  • Combination of paclitaxel and carboplatin as second-line therapy for patients with metastatic melanoma.

    abstract:BACKGROUND:Patients with metastatic melanoma (MM) have very few therapy options. Based on reports of responses to paclitaxel and carboplatin (PC), 31 patients with MM were treated with PC. METHODS:Data regarding patients treated with PC were abstracted from medical records. Clinical outcomes as determined by the treat...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.21611

    authors: Rao RD,Holtan SG,Ingle JN,Croghan GA,Kottschade LA,Creagan ET,Kaur JS,Pitot HC,Markovic SN

    更新日期:2006-01-15 00:00:00

  • Uveal melanoma: From diagnosis to treatment and the science in between.

    abstract::Melanomas of the choroid, ciliary body, and iris of the eye are collectively known as uveal melanomas. These cancers represent 5% of all melanoma diagnoses in the United States, and their age-adjusted risk is 5 per 1 million population. These less frequent melanomas are dissimilar to their more common cutaneous melano...

    journal_title:Cancer

    pub_type: 杂志文章,评审

    doi:10.1002/cncr.29727

    authors: Chattopadhyay C,Kim DW,Gombos DS,Oba J,Qin Y,Williams MD,Esmaeli B,Grimm EA,Wargo JA,Woodman SE,Patel SP

    更新日期:2016-08-01 00:00:00

  • Radiation therapy of epithelioid sarcoma.

    abstract::Epithelioid sarcoma is an uncommon tumor characterized by its appearance in the distal extremities (especially the forearm, wrist, and ankle), the tendency to recur locally, and high probability of spread to regional lymph nodes. Most patients have been treated surgically, and the potential role of radiation therapy a...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19830915)52:6<1022::aid-cncr2820

    authors: Shimm DS,Suit HD

    更新日期:1983-09-15 00:00:00

  • Aggressive cutaneous malignancies following cardiothoracic transplantation: the Australian experience.

    abstract:BACKGROUND:The development of malignancies in recipients of a cardiothoracic transplant (CTT)--that is, heart, lung, or heart and lung recipients-is of concern. Cutaneous and lymphoproliferative malignancies comprise the two major groups of malignancies encountered. A small subgroup of patients will develop potentially...

    journal_title:Cancer

    pub_type: 杂志文章,评审

    doi:

    authors: Veness MJ,Quinn DI,Ong CS,Keogh AM,Macdonald PS,Cooper SG,Morgan GW

    更新日期:1999-04-15 00:00:00

  • C-erbB-2 oncogene protein in in situ and invasive lobular breast neoplasia.

    abstract::Lobular carcinoma in situ (LCIS) has uncertain malignant potential; biologic markers that will identify patients at risk for a poor clinical outcome have been sought actively. Amplification of the c-erbB-2 protooncogene has been correlated with poor prognosis in invasive mammary carcinoma, and immunohistochemical eval...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19910715)68:2<331::aid-cncr28206

    authors: Porter PL,Garcia R,Moe R,Corwin DJ,Gown AM

    更新日期:1991-07-15 00:00:00

  • Chemoprevention of bladder cancer.

    abstract::There is a growing body of basic science and epidemiologic evidence to support a research thrust to determine whether several natural or synthetic agents, given alone or together, can lower cancer incidence. Candidate agents include analogs of vitamin A and the vitamin A precursor, beta-carotene, vitamins C and E, and...

    journal_title:Cancer

    pub_type: 临床试验,杂志文章

    doi:10.1002/1097-0142(19870801)60:3+<650::aid-cncr2820

    authors: Malone WF,Kelloff GJ,Pierson H,Greenwald P

    更新日期:1987-08-01 00:00:00

  • Cancer in collagen disease. A statistical analysis by reviewing the Annual of Pathological Autopsy Cases (Nippon Boken Shuho) in Japan.

    abstract::Cases of systemic lupus erythematosus, systemic sclerosis, periarteritis nodosa, and dermato- and polymyositis autopsied in Japan during a recent, 7-year period (1972-1978) were studied to assess the incidence of cancer as a complication. In comparison with the other three groups, cases of dermato- and polymyositis (D...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19841101)54:9<1841::aid-cncr2820

    authors: Okayasu I,Mizutani H,Kurihara H,Yanagisawa F

    更新日期:1984-11-01 00:00:00

  • Sperm cryopreservation before cancer chemotherapy helps in the emotional battle against cancer.

    abstract:BACKGROUND:Sperm cryopreservation before cancer chemotherapy is available for young patients with cancer. However, few patients bank their sperm. The authors evaluated by questionnaire the psychological impact of sperm cryopreservation. METHODS:The authors cryopreserved the sperm of 111 patients with cancer for free a...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.21185

    authors: Saito K,Suzuki K,Iwasaki A,Yumura Y,Kubota Y

    更新日期:2005-08-01 00:00:00

  • Gauging the impact of breast carcinoma screening in terms of tumor size and death rate.

    abstract:BACKGROUND:While the question of whether the trials of breast cancer screening have resulted in a reduction in breast cancer death has been the subject of much scrutiny, there has been less attention to the reduction in tumor size achieved by screening. METHODS:Size data for invasive breast tumors were assembled from ...

    journal_title:Cancer

    pub_type: 杂志文章,meta分析

    doi:10.1002/cncr.11766

    authors: Michaelson JS,Satija S,Kopans D,Moore R,Silverstein M,Comegno A,Hughes K,Taghian A,Powell S,Smith B

    更新日期:2003-11-15 00:00:00

  • A pathologic assessment of tumor residue and stromal changes after intraarterial chemotherapy for head and neck carcinomas. A study on serial sections of the whole surgical specimen.

    abstract::Thirty-one patients with advanced, biopsy-proven squamous cell carcinoma (SCC) of the head and neck were treated with intraarterial chemotherapy (IAC) and subsequent radical surgery. Cisplatin at 25 mg/d (4 hours of infusion) and bleomycin at 15 mg/d (20 hours of infusion) were administered for 10 consecutive days. Ra...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19890901)64:5<994::aid-cncr28206

    authors: Sulfaro S,Frustaci S,Volpe R,Barzan L,Comoretto R,Monfardini S,Carbone A

    更新日期:1989-09-01 00:00:00

  • A scanning electron microscopy study of changes in the colonic mucus layer during chemical carcinogenesis.

    abstract::Scanning electron microscopy was used to examine the appearances of the colonic mucus layer of rats during chemical carcinogenesis with dimethylhydrazine. The normal colonic mucus layer had a dense homogeneous appearance and provided a complete cover for the mucosal epithelium. At high magnifications tiny fenestration...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19830515)51:10<1847::aid-cncr282

    authors: Traynor OJ,Costa NL,Wood CB

    更新日期:1983-05-15 00:00:00

  • Primary retroperitoneal seminoma.

    abstract::In a retrospective review (1950-1975) of the Mayo Clinic experience with seminomas (483 cases), twelve patients (2.5%) were found to have a retroperitoneal seminoma without evidence of testicular involvement. The mean age was 47 years (range, 31-67). Eleven patients were treated by radiation alone, with doses ranging ...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19820501)49:9<1934::aid-cncr2820

    authors: Buskirk SJ,Evans RG,Farrow GM,Earle JD

    更新日期:1982-05-01 00:00:00

  • Malignant lymphoepithelial lesion of the parotid gland: poorly differentiated squamous cell carcinoma with lymphoid stroma.

    abstract::The case of a European patient with a malignant lymphoepithelial lesion of epithelial type is presented. This type of tumor has an exceptionally high incidence among Eskimos. To the authors' knowledge this is the first case reported with an ultrastructural study that demonstrates the squamous nature of the tumor cells...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19810715)48:2<289::aid-cncr28204

    authors: Redondo C,Garcia A,Vazquez F

    更新日期:1981-07-15 00:00:00

  • The role of clofarabine in hematologic and solid malignancies--development of a next-generation nucleoside analog.

    abstract::Clofarabine is a new-generation nucleoside analog that has been synthesized to combine the most favorable pharmacokinetic properties of its congeners fludarabine and cladribine. In addition to inhibition of DNA polymerases and DNA synthesis, clofarabine acts as a strong inhibitor of ribonucleotide reductase (RnR), an ...

    journal_title:Cancer

    pub_type: 杂志文章,评审

    doi:10.1002/cncr.21005

    authors: Faderl S,Gandhi V,Keating MJ,Jeha S,Plunkett W,Kantarjian HM

    更新日期:2005-05-15 00:00:00

  • Disparities in hepatocellular carcinoma incidence by race/ethnicity and geographic area in California: Implications for prevention.

    abstract:BACKGROUND:The incidence of hepatocellular carcinoma (HCC) has been rising rapidly in the United States. California is an ethnically diverse state with the largest number of incident HCC cases in the country. Characterizing HCC disparities in California may inform priorities for HCC prevention. METHODS:By using data f...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.31598

    authors: Yang B,Liu JB,So SK,Han SS,Wang SS,Hertz A,Shariff-Marco S,Lin Gomez S,Rosenberg PS,Nguyen MH,Hsing AW

    更新日期:2018-09-01 00:00:00

  • Transition of Ki-67 index of uterine cervical tumors during radiation therapy. Immunohistochemical study.

    abstract::Histopathologic and Ki-67-staining features of cancer cells were investigated in biopsy specimens before and during radiation therapy in 29 patients with cervical squamous cell carcinoma. No morphologic changes were observed up to doses of 540 cGy. A few intact cancer cells remained up to doses of 2700 cGy. Moderate c...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19910801)68:3<517::aid-cncr28206

    authors: Nakano T,Oka K

    更新日期:1991-08-01 00:00:00

  • Functional insulin receptors are overexpressed in thyroid tumors: is this an early event in thyroid tumorigenesis?

    abstract:BACKGROUND:Insulin receptor (IR), a member of the receptor tyrosine kinase family, is expressed in normal thyroid cells and affects thyroid cell proliferation and differentiation. METHODS:The authors measured IR content in benign and malignant thyroid tumors by three independent methods: a specific radioimmunoassay, 1...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/(sici)1097-0142(19990115)85:2<492::aid-cnc

    authors: Frittitta L,Sciacca L,Catalfamo R,Ippolito A,Gangemi P,Pezzino V,Filetti S,Vigneri R

    更新日期:1999-01-15 00:00:00

  • DNA methylation of genes linked with retinoid signaling in gastric carcinoma: expression of the retinoid acid receptor beta, cellular retinol-binding protein 1, and tazarotene-induced gene 1 genes is associated with DNA methylation.

    abstract:BACKGROUND:Hypermethylation of CpG islands has been associated with silencing of various tumor suppressor genes, and the retinoid acid receptor beta (RARbeta), cellular retinol-binding protein 1 (CRBP1), and tazarotene-induced gene 1 (TIG1) genes have been associated with retinoic acid signaling. To the authors' knowle...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.21392

    authors: Shutoh M,Oue N,Aung PP,Noguchi T,Kuraoka K,Nakayama H,Kawahara K,Yasui W

    更新日期:2005-10-15 00:00:00

  • Value of cytologic Papanicolaou smears and polymerase chain reaction screening for human papillomavirus DNA in detecting anal intraepithelial neoplasia: comparison with histology of a surgical sample.

    abstract:BACKGROUND:The performance of cytologic screening and its correlation with histology and polymerase chain reaction (PCR) detection of human papillomavirus (HPV) DNA have not been evaluated in populations with a low prevalence of anal intraepithelial neoplasia (AIN). The objective of the current study was to analyze the...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.27671

    authors: Etienney I,Vuong S,Si-Mohamed A,Fléjou JF,Atienza P,Bauer P,Cytological Diaconesses Group.

    更新日期:2012-12-15 00:00:00

  • A population-based study of prevalence of complementary methods use by cancer survivors: a report from the American Cancer Society's studies of cancer survivors.

    abstract:BACKGROUND:The use of complementary methods (CMs) is widespread and increasing in the United States. Most literature on CM use among cancer survivors focuses on the treatment period, whereas only a few studies address use further along the cancer continuum. METHODS:This study analyzed the prevalence and the medical an...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.23659

    authors: Gansler T,Kaw C,Crammer C,Smith T

    更新日期:2008-09-01 00:00:00

  • Extremity and trunk desmoid tumors: a multifactorial analysis of outcome.

    abstract:BACKGROUND:The natural history of desmoid tumors remains an enigma. Previous reports attempting to identify their biology have included recurrent and primary tumors as well as tumors from both intra- and extra-abdominal sites. The purpose of this study was to analyze patients with primary extremity and trunk desmoid tu...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:

    authors: Merchant NB,Lewis JJ,Woodruff JM,Leung DH,Brennan MF

    更新日期:1999-11-15 00:00:00

  • Humoral immune response in melanoma and glioma patients: a solubilized melanoma-membrane component as a tool for detecting circulating antibodies.

    abstract::In search of tumor-associated components in human melanomas and gliomas, plasma membranes were isolated from these tumors and compared morphologically, biochemically and immunologically with those from normal human brain. The preparations exhibited a comparable ultrastructure of empty vesicles of various form and size...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19811201)48:11<2399::aid-cncr282

    authors: Birkmayer GD

    更新日期:1981-12-01 00:00:00

  • Physical activity and survival of postmenopausal, hormone receptor-positive breast cancer patients: results of the Tamoxifen Exemestane Adjuvant Multicenter Lifestyle study.

    abstract:BACKGROUND:Physical activity has been related to improved breast cancer outcomes. Especially in the older breast cancer population, physical activity may be important because old age is associated with comorbidities and decreased physical function. The purpose of this study was to investigate the relation between physi...

    journal_title:Cancer

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1002/cncr.28783

    authors: de Glas NA,Fontein DB,Bastiaannet E,Pijpe A,De Craen AJ,Liefers GJ,Nortier HJ,de Haes HJ,van de Velde CJ,van Leeuwen FE

    更新日期:2014-09-15 00:00:00

  • Prediction of survival in patients with metastases in the spinal column: results based on a randomized trial of radiotherapy.

    abstract:BACKGROUND:Adequate prediction of survival is important in deciding on treatment for patients with symptomatic spinal metastases. The authors reviewed 342 patients with painful spinal metastases without neurologic impairment who were treated conservatively within a large, prospectively randomized radiotherapy trial. Re...

    journal_title:Cancer

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1002/cncr.20756

    authors: van der Linden YM,Dijkstra SP,Vonk EJ,Marijnen CA,Leer JW,Dutch Bone Metastasis Study Group.

    更新日期:2005-01-15 00:00:00

  • Cost-effectiveness of systemic and regional chemotherapy for the treatment of patients with unresectable colorectal liver metastases.

    abstract:BACKGROUND:Management of unresectable colorectal liver metastases (CLM) can be by regional (hepatic arterial infusion [HAI]) or systemic chemotherapy, or by symptom control alone. In this study the costs of each type of management were related to clinical outcome in 134 patients with CLM. METHODS:The costs (both in te...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:

    authors: Durand-Zaleski I,Earlam S,Fordy C,Davies M,Allen-Mersh TG

    更新日期:1998-09-01 00:00:00

  • Non-Hodgkin's lymphoma in bone. Pathologic and radiologic features with clinical correlates.

    abstract::Thirty-seven lymphomas of bone were studied, including 33 diffuse large cell lymphomas, three undifferentiated (small noncleaved cell) lymphomas, and one well-differentiated (small) lymphocytic lymphoma. The large cell lymphomas were subclassified as large cleaved, large noncleaved, multilobated cell, and immunoblasti...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19871115)60:10<2494::aid-cncr282

    authors: Clayton F,Butler JJ,Ayala AG,Ro JY,Zornoza J

    更新日期:1987-11-15 00:00:00

  • Results in patients with breast cancer treated by radical mastectomy and postoperative irradiation with no adjuvant chemotherapy.

    abstract::In 1963 an electron beam became available, making irradiation of the chest wall technically easy. In addition to peripheral lymphatic irradiation in patients with positive axillary nodes and/or the tumor in the inner quadrants or centrally located, patients with tumor larger than 5 cm or with grave signs and/or a sign...

    journal_title:Cancer

    pub_type: 临床试验,杂志文章

    doi:10.1002/1097-0142(19820315)49:6<1316::aid-cncr2820

    authors: Tapley ND,Spanos WJ Jr,Fletcher GH,Montague ED,Schell S,Oswald MJ

    更新日期:1982-03-15 00:00:00

  • Fine-needle aspiration biopsy of the pancreas complicated by pancreatic ascites.

    abstract::A case is reported of a patient with pancreatic carcinoma who developed pancreatic ascites after intraoperative fine-needle aspiration cytology (FNAC) biopsy. This complication of FNAC has not previously been reported to the authors' knowledge. The literature is reviewed, and FNAC is shown to be the safest method of p...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19900601)65:11<2537::aid-cncr282

    authors: Rosenbaum DA,Frost DB

    更新日期:1990-06-01 00:00:00

  • Remission of rapidly growing desmoid tumors after tamoxifen therapy.

    abstract::A patient is described with Gardner's syndrome manifested initially by an extra-abdominal desmoid which was resected. The case was complicated by metastatic adenocarcinoma of the colon and recurrence of several large painful desmoid lesions. In view of the predilection of desmoids to occur in women in their childbeari...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19831215)52:12<2201::aid-cncr282

    authors: Kinzbrunner B,Ritter S,Domingo J,Rosenthal CJ

    更新日期:1983-12-15 00:00:00