Transition of Ki-67 index of uterine cervical tumors during radiation therapy. Immunohistochemical study.

abstract：BACKGROUND:Although pediatric cancer mortality and survival have improved in the United States over the past 40 years, differences exist by age, race/ethnicity, cancer site, and economic status. To assess progress, this study examined recent mortality and survival data for individuals younger than 20 years. METHODS:Ag...

journal_title：Cancer

authors： Siegel DA,Richardson LC,Henley SJ,Wilson RJ,Dowling NF,Weir HK,Tai EW,Buchanan Lunsford N

更新日期：2020-10-01 00:00:00

abstract：:The relation of gastric acid-secreting function to the gross and histological types and locations of carcinomas was examined in 53 patients with early gastric carcinomas. Studies were made by the endoscopic Congo red test developed in this clinic. Results indicated a close correlation between the gross and histologica...

journal_title：Cancer

authors： Tatsuta M,Okuda S,Taniguchi H,Tamura H

更新日期：1979-01-01 00:00:00

abstract：:Ultrastructural examination of an alveolar rhabdomyosarcoma revealed that the bulk of the tumor was composed of small polygonal cells containing polyribosomes, short strands of rough endoplasmic reticulum, and variable amounts of glycogen; the cells were joined by small desmosome-like structures. Similar cells, as wel...

journal_title：Cancer

authors： Churg A,Ringus J

更新日期：1978-04-01 00:00:00

abstract：:Sixty-six consecutive cases of carcinoma of the lower lip were seen at the Indiana University Hospitals from 1960 to 1972. Each patient's records were reviewed as to age, sex, race, stage, stage by treatment modality, pathology, treatment methods used and cause of failure. Early lip cancer represents a highly curative...

journal_title：Cancer

authors： Hornback NB,Shidnia H

更新日期：1978-01-01 00:00:00

abstract：BACKGROUND:Splenic and nodal marginal zone lymphomas (MZL) are subtypes of marginal zone-derived neoplasms. Due to their rarity, little is known concerning their relation, pattern of dissemination, and treatment outcome. METHODS:The authors analyzed the clinicopathologic features and outcome of 43 patients (34 patient...

journal_title：Cancer

authors： Arcaini L,Paulli M,Boveri E,Vallisa D,Bernuzzi P,Orlandi E,Incardona P,Brusamolino E,Passamonti F,Burcheri S,Schena C,Pascutto C,Cavanna L,Magrini U,Lazzarino M

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:The poor prognosis reported for patients with high-grade glial neoplasms indicates a need for the development of multimodality therapeutic approaches. The addition of chemotherapy has contributed variably to increased survival. The objective of the current study (Southwest Oncology Group [SWOG] 9016) was to ...

journal_title：Cancer

authors： Blumenthal DT,Rankin C,Eyre HJ,Livingston RB,Spence AM,Stelzer KJ,Rushing EJ,Berger MS,Rivkin SE,Cohn AL,Petersdorf SH

更新日期：2008-08-01 00:00:00

abstract：:Seventy-six patients with malignant germ cell tumors of the ovary received vincristine, dactinomycin, and cyclophosphamide (VAC) postoperatively. Fifty-four were treated after removal of all gross disease. The majority of these remain disease-free. Indeed, only 15 (28%) have failed, including 11 of 24 with pure endode...

journal_title：Cancer

authors： Slayton RE,Park RC,Silverberg SG,Shingleton H,Creasman WT,Blessing JA

更新日期：1985-07-15 00:00:00

abstract：:Fifteen patients developed acute nonlymphocytic leukemia (ANLL) 31 to 182 months following chemotherapy and/or radiotherapy for various malignancies and one non-neoplastic disorder. The ANLL was commonly heralded by a brief preleukemic phase consisting of cytopenias and a variety of morphologic abnormalities. At diagn...

journal_title：Cancer

authors： Foucar K,McKenna RW,Bloomfield CD,Bowers TK,Brunning RD

更新日期：1979-04-01 00:00:00

abstract：:Cancer is the second most common cause of death among those aged > or =65 years, and is a major cause of morbidity. There is some evidence that screening, by detecting precancerous lesions in asymptomatic patients, is effective in reducing cancer-related morbidity and mortality among older men and women. The objective...

journal_title：Cancer

authors： Sheinfeld Gorin S,Gauthier J,Hay J,Miles A,Wardle J

更新日期：2008-12-15 00:00:00

abstract：:Until recently the prognosis of childhood non-Hodgkin's lymphoma has been poor. A program of combination chemotherapy and involved area radiotherapy was instituted in the Department of Pediatrics at Roswell Park Memorial Institute in 1971. Thirty-one biopsy proven untreated children entered this study. There were 4 St...

journal_title：Cancer

authors： Brecher ML,Sinks LF,Thomas RR,Freeman AI

更新日期：1978-05-01 00:00:00

abstract：BACKGROUND:Thyroid tumorigenesis is characterized by a progressive loss of differentiation exhibited by a range of disease variants. The Notch receptor family (1-4) regulates developmental progression in both normal and cancerous tissues. This study sought to characterize the third Notch isoform (Notch3) across the var...

journal_title：Cancer

authors： Somnay YR,Yu XM,Lloyd RV,Leverson G,Aburjania Z,Jang S,Jaskula-Sztul R,Chen H

更新日期：2017-03-01 00:00:00

abstract：:Fourteen patients with adenocarcinoma of the gastrointestinal tract and pancreas treated with mitomycin C(MMC) and 5-fluorouracil (5-FU) had renal impairment 6-11 months from the beginning of MMC therapy. Two clinical entities were recognized: an acute fulminating renal failure that was rapidly fatal and a chronic slo...

journal_title：Cancer

authors： Hanna WT,Krauss S,Regester RF,Murphy WM

更新日期：1981-12-15 00:00:00

abstract：:Acquired myeloperoxidase deficiency has been reported in several hematological malignancies. The clinical course of a patient with acute myelomonocytic leukemia is described which was characterized by staphylococcal infections prior to therapy and again during a period of relapse. Neutropenia was not a feature of thes...

journal_title：Cancer

authors： Kitahara M,Kushner JP

更新日期：1979-12-01 00:00:00

abstract：BACKGROUND:Quality assurance (QA) of clinical practice is important for any medical specialty. Programs based on the Patterns of Care Study (PCS) have been developed to compare the quality of radiotherapeutic care at individual institutions, with the national average representing the process and outcome of radiotherapy...

journal_title：Cancer

authors： Tanisada K,Teshima T,Ohno Y,Inoue T,Abe M,Ikeda H,Owen JB,Hanks GE,Masuda K,Honke Y

更新日期：2002-07-01 00:00:00

abstract：BACKGROUND:There is controversy regarding the effect of age on breast carcinoma, and previous analyses have often excluded the most elderly patients as well as those with advanced cancers. This study assessed treatment variations and outcome in relation to age for a complete series of patients who presented with breast...

journal_title：Cancer

authors： Golledge J,Wiggins JE,Callam MJ

更新日期：2000-01-15 00:00:00

abstract：:Higher serum iron and ferritin levels noted in hepatitis B antigen (HBAg) carriers than in noncarriers suggests that virus might actively replicate in hepatocytes, stimulate ferritin synthesis, and result in increased liver iron stores. A comparative semiquantitative study of immunohistochemical ferritin (0-12) and he...

journal_title：Cancer

authors： Cohen C,Berson SD,Shulman G,Budgeon LR

更新日期：1985-11-01 00:00:00

abstract：BACKGROUND:To propose 'never-smoking nonsmall cell lung cancer (NSCLC)' as a separate entity, the clinicopathologic differences of operable NSCLC between never-smoking patients and patients with a history of smoking were investigated. METHODS:The medical records of 1405 patients with primary NSCLC who underwent a comp...

journal_title：Cancer

authors： Yano T,Miura N,Takenaka T,Haro A,Okazaki H,Ohba T,Kouso H,Kometani T,Shoji F,Maehara Y

更新日期：2008-09-01 00:00:00

abstract：BACKGROUND:Preclinical and clinical data suggest that both leucovorin (LV) and interferon (IFN) can augment the cytotoxic effects of 5-fluorouracil (5-FU). Based on the rationale of biochemical double modulation, the current Phase II study was undertaken. METHODS:Thirty-two previously untreated patients with advanced ...

journal_title：Cancer

authors： Scheithauer W,Pfeffel F,Kornek G,Marczell A,Wiltschke C,Funovics J

更新日期：1992-10-01 00:00:00

abstract：:Routinely embedded tumors (116 cases) were screened immunohistochemically for the thyroid-associated antigens, thyroglobulin and calcitonin, and for carcinoembryonic antigen (CEA). Also the influence of different fixatives, decalcification, and embedding procedures were studied. All follicular and papillary carcinomas...

journal_title：Cancer

authors： Logmans SC,Jöbsis AC

更新日期：1984-07-15 00:00:00

abstract：:Sixty-two patients with acute leukemia who remained in continuous complete remission for 8 to 45 months received three courses of intensified therapy with new chemotherapeutic agents, after which they received no further chemotherapy. Immunotherapy with BCG was then administered to 55 of these patients. They have been...

journal_title：Cancer

authors： Bodey GP,Freireich EJ,McCredie KB,Smith TL,Gehan EA,Gutterman JU,Hersh EM

更新日期：1981-04-15 00:00:00

abstract：:Disulfiram (tetraethylthiuram disulfide, Antabuse) and sodium diethyldithiocarbamate, when added to the diet, inhibit 1,2-dimethylhydrazine (DMH)-induced neoplasia of the large bowel in female CF1 mice. Ethylene bis(dithiocarbamato)manganese (Maneb) and bis(ethylxanthogen), two pesticides with structural similarities ...

journal_title：Cancer

authors： Wattenberg LW,Lam LK,Fladmoe AV,Borchert P

更新日期：1977-11-01 00:00:00

abstract：BACKGROUND:Image-directed biopsies may be collected as histologic or cytologic specimens. METHODS:In 34 patients, the results of aspiration cytologic examination were compared prospectively with core tissue biopsy findings obtained and diagnosed independently using the same image-guided procedure. RESULTS:Cytologic e...

journal_title：Cancer

authors： Jonasson JG,Wang HH,Porter DH,Tyagi G,Ducatman BS

更新日期：1992-10-15 00:00:00

abstract：:A patient with acute lymphoblastic leukemia who had received CNS sanctuary treatment with cranial X-irradiation and intrathecal methotrexate displayed his first sign of relapse as iritis with malignant hypopyon. Treatment included topical and subconjunctival corticosteroids and local X-irradiation. Leukemic infiltrati...

journal_title：Cancer

authors： Gruenewald RL,Perry MC,Henry PH

更新日期：1979-10-01 00:00:00

abstract：:From January, 1973, to June, 1976, 226 patients with palpable ovarian masses were evaluated preoperatively by lymphography. Histology showed 166 cases of malignant epithelial tumors, 26 benign tumors, and 34 malignant special tumors (not included in this report). Furthermore, the group of patients included 99 recurren...

journal_title：Cancer

authors： Musumeci R,Banfi A,Bolis G,Candiani GB,De Palo G,Di Re F,Lucina L,Lattuada A,Mangioni C,Mattioli G,Natale N

更新日期：1977-10-01 00:00:00

abstract：BACKGROUND:Although several refinements have been reported for breast magnetic resonance imaging (MRI), there has been no uniform agreement by researchers on the optimal method. The authors report a simple and effective MRI method that incorporated the best qualities of other breast MRI methods yet eliminated the compl...

journal_title：Cancer

authors： Khatri VP,Stuppino JJ,Espinosa MH,Pollack MS

更新日期：2001-08-01 00:00:00

abstract：:The effect of multimodal immunotherapy was studied in rats bearing primary gastrointestinal tumors induced by 1,2-dimethylhydrazine dihydrochloride. Multimodal immune manipulation consisted of combinations of splenectomy, C. parvum, unblocking serum, unblocked lymphoid cells, and levamisole. Such immunologic intervent...

journal_title：Cancer

authors： Bansal BR,Mobini J,Bansal SC

更新日期：1978-11-01 00:00:00

abstract：:The cases of three patients with primary carcinoid tumor of the testis were reported. The patients were 41, 44, and 83 years of age. At initial examination, all three had testicular masses with or without associated pain, and none had the carcinoid syndrome. The tumors measured 4.3 cm, 3.0 cm, and 6.5 cm in dimension....

journal_title：Cancer

authors： Zavala-Pompa A,Ro JY,el-Naggar A,Ordóñez NG,Amin MB,Pierce PD,Ayala AG

更新日期：1993-09-01 00:00:00

abstract：BACKGROUND:Glembatumumab vedotin is an antibody-drug conjugate that produced preliminary clinical activity against advanced melanoma in a phase 1 dose-escalation trial. The objective of the current study was to investigate further the antitumor activity of glembatumumab vedotin at the recommended phase 2 dose in heavil...

journal_title：Cancer

authors： Ott PA,Pavlick AC,Johnson DB,Hart LL,Infante JR,Luke JJ,Lutzky J,Rothschild NE,Spitler LE,Cowey CL,Alizadeh AR,Salama AK,He Y,Hawthorne TR,Bagley RG,Zhang J,Turner CD,Hamid O

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND:Pericolorectal tumor deposits (TDs) are associated with adverse outcomes in patients with colorectal cancer, and the seventh edition of the American Joint Committee on Cancer (AJCC) staging system recently classified TDs without regional lymph node metastasis as category N1c. However, the definition of TDs h...

journal_title：Cancer

authors： Song JS,Chang HJ,Kim DY,Kim SY,Baek JY,Park JW,Park SC,Choi HS,Oh JH

更新日期：2011-09-01 00:00:00

abstract：:Previous studies and those of the authors have reported about raised levels of lipid-bound sialic acid (LSA) in sera of patients with various neoplasms. Most authors have used the method of Katopodis and Stock for isolating serum LSA. Because of the discrepancy of the amount of extracted LSA with the content of pure g...

journal_title：Cancer

authors： Voigtmann R,Pokorny J,Meinshausen A

更新日期：1989-12-01 00:00:00