Non-Hodgkin's lymphoma in children.

abstract：:To additionally understand the molecular mechanisms and biologic indicators of colonic tumorigenesis through the adenoma-carcinoma sequence, protein kinase C (PKC) activity was examined in the cytosol and particulate fraction of specimen homogenates from 18 human colonic carcinomas and seven coexisting colonic adenoma...

journal_title：Cancer

authors： Kusunoki M,Sakanoue Y,Hatada T,Yanagi H,Yamamura T,Utsunomiya J

更新日期：1992-01-01 00:00:00

abstract：:Xenografts have been established in immune-suppressed mice from three embryonal cell carcinomas, two yolk sac carcinomas, and a 'seminoma-like' tumor that produces alphafetoprotein. The ultrastructural features of these xenografts have been studied in detail and compared with human germ cell tumors removed from patien...

journal_title：Cancer

authors： Monaghan P,Raghavan D,Neville AM

更新日期：1982-02-15 00:00:00

abstract：BACKGROUND:To the authors' knowledge, outcomes and prognostic tools have yet to be clearly defined in patients with metastatic renal cell carcinoma (mRCC) who are treated with immuno-oncology (IO) checkpoint inhibitors (programmed death-ligand 1 [PD-L1] inhibitors). In the current study, the authors aimed to establish ...

journal_title：Cancer

authors： Yip SM,Wells C,Moreira R,Wong A,Srinivas S,Beuselinck B,Porta C,Sim HW,Ernst DS,Rini BI,Yuasa T,Basappa NS,Kanesvaran R,Wood LA,Canil C,Kapoor A,Fu SYF,Choueiri TK,Heng DYC

更新日期：2018-09-15 00:00:00

abstract：:Extremely high concentrations of human chorionic gonadotropin in the cerebrospinal fluid were found in a 5-year-old boy presenting sexual precocity and leg pain. An intramedullary spinal cord tumor was revealed by myelogram and metrizamide computerized tomography, and a biopsy specimen taken at laminectomy. Histologic...

journal_title：Cancer

authors： Hisa S,Morinaga S,Kobayashi Y,Ojima M,Chikaoka H,Sasano N

更新日期：1985-06-15 00:00:00

abstract：BACKGROUND:The role of adjuvant therapy in the management of patients with malignant mixed Müllerian tumors (MMMT) of the uterus has not been defined. The outcome of planned multimodality therapy for patients with apparent early stage disease was assessed. METHODS:A pilot study was performed on 38 patients with clinic...

journal_title：Cancer

authors： Manolitsas TP,Wain GV,Williams KE,Freidlander M,Hacker NF

更新日期：2001-04-15 00:00:00

abstract：:A human liposarcoma cell line COLO 222, derived from a primary tumor in a 62-year-old male, elaborates hyaluronic acid. COLO 222 is characterized on the basis of histochemical, ultramorphological, and cytogenetic properties, along with isozyme phenotype and cell products. A chromosome mode of 53 predominates and uniqu...

journal_title：Cancer

authors： Morgan RT,Quinn LA,Moore GE,Semple TU,Woods LK

更新日期：1980-03-15 00:00:00

abstract：BACKGROUND:Image-directed biopsies may be collected as histologic or cytologic specimens. METHODS:In 34 patients, the results of aspiration cytologic examination were compared prospectively with core tissue biopsy findings obtained and diagnosed independently using the same image-guided procedure. RESULTS:Cytologic e...

journal_title：Cancer

authors： Jonasson JG,Wang HH,Porter DH,Tyagi G,Ducatman BS

更新日期：1992-10-15 00:00:00

abstract：BACKGROUND:Recently, invasion of vascular spaces by endometrial carcinoma has received particular attention as a prognostic factor. The goal of the current investigation was to re-examine the effect of vascular invasion on tumor recurrence and survival in patients with endometrial carcinoma. METHODS:Surgical specimens...

journal_title：Cancer

authors： Inoue Y,Obata K,Abe K,Ohmura G,Doh K,Yoshioka T,Hoshiai H,Noda K

更新日期：1996-10-01 00:00:00

abstract：:The discovery of genes responsible for inherited forms of colorectal cancer have the potential to improve cancer risk assessment and counseling. Germline mutations (nonsense, frameshift) of APC are associated with familial adenomatous polyposis, an autosomal dominant syndrome, clinically characterized by young onset, ...

journal_title：Cancer

authors： Petersen GM,Brensinger JD,Johnson KA,Giardiello FM

更新日期：1999-12-01 00:00:00

abstract：BACKGROUND:Disparities in treatment and mortality for colorectal cancer (CRC) may reflect differences in access to specialized care or other characteristics of the area where an individual lives. METHODS:Surveillance, Epidemiology and End Results Program-Medicare data for seniors diagnosed with CRC were linked to area...

journal_title：Cancer

authors： Haas JS,Brawarsky P,Iyer A,Fitzmaurice GM,Neville BA,Earle C

更新日期：2011-09-15 00:00:00

abstract：:Granulocyte (PMN) directional locomotion (migration) in vitro and in vivo, resting nitroblue tetrazolium (NBT)-reduction and adherence to nylon wool of polymorphonuclear neutrophils (PMN) were assayed in 7 patients with Hodgkin's disease (HD) and in 11 patients with non-Hodgkin's lymphoma (NHL) prior to therapy. In mo...

journal_title：Cancer

authors： Von Fliedner V,Salvatori V,Higby DJ,Stutzman L,Park BH

更新日期：1980-02-01 00:00:00

abstract：:A case of biliary cystadenoma undergoing malignant dedifferentiation is presented. Biliary cystadenocarcinoma is an infrequently occurring neoplasm; fewer than 20 cases have been reported in the literature. This case is the first in which there is documentation of cystadenocarcinoma arising from a previously diagnosed...

journal_title：Cancer

authors： Woods GL

更新日期：1981-06-15 00:00:00

abstract：BACKGROUND:The authors investigated the putative surrogate endpoints of best response, complete response (CR), confirmed response, and progression-free survival (PFS) for associations with overall survival (OS), and as possible surrogate endpoints for OS. METHODS:Individual patient data from 870 untreated extensive st...

journal_title：Cancer

authors： Foster NR,Qi Y,Shi Q,Krook JE,Kugler JW,Jett JR,Molina JR,Schild SE,Adjei AA,Mandrekar SJ

更新日期：2011-03-15 00:00:00

abstract：BACKGROUND:Proliferating cell nuclear antigen (PCNA) is an intranuclear protein that is linked closely to the cell cycle. An immunohistochemical study was performed on the expression of PCNA in various sized hepatocellular carcinomas (HCCs) to determine the relation between the proliferative activity of cancer cells an...

journal_title：Cancer

authors： Suehiro T,Matsumata T,Itasaka H,Yamamoto K,Kawahara N,Sugimachi K

更新日期：1995-08-01 00:00:00

abstract：:Histopathologic and Ki-67-staining features of cancer cells were investigated in biopsy specimens before and during radiation therapy in 29 patients with cervical squamous cell carcinoma. No morphologic changes were observed up to doses of 540 cGy. A few intact cancer cells remained up to doses of 2700 cGy. Moderate c...

journal_title：Cancer

authors： Nakano T,Oka K

更新日期：1991-08-01 00:00:00

abstract：:This study delineates the temporal relationship between immune complex formation and tumor growth, and provides one possible explanation for host immunosuppression during tumor growth. The authors have studied serial circulating immune complex (CIC) levels and interleukin (IL) elaboration by peripheral blood cells (IL...

journal_title：Cancer

authors： Ravikumar T,Steele G Jr,Rodrick M,Ross D,Wilson R,Lahey S,Wright D,Munroe A,King V

更新日期：1984-03-15 00:00:00

abstract：:The pathologic features, clinical presentation and natural history of hepatocellular carcinoma (HCC) developing in the noncirrhotic liver were studied in 61 patients against a background of 63 patients seen concurrently with HCC complicating cirrhosis. Noncirrhotic HCC had a bimodal age distribution, with females pred...

journal_title：Cancer

authors： Smalley SR,Moertel CG,Hilton JF,Weiland LH,Weiand HS,Adson MA,Melton LJ 3rd,Batts K

更新日期：1988-10-01 00:00:00

abstract：BACKGROUND:Abnormalities in chromosome 11q13 regions have been frequently found in head and neck squamous carcinoma. Recent studies indicate that the PRAD-1 (also CCND1), which encodes cyclin D1, is a putative oncogene that is an important component of this region. METHODS:DNA was extracted from 32 snap-frozen specime...

journal_title：Cancer

authors： Callender T,el-Naggar AK,Lee MS,Frankenthaler R,Luna MA,Batsakis JG

更新日期：1994-07-01 00:00:00

abstract：BACKGROUND:Chemotherapy improves survival for patients with stage III colon cancer, but some older patients with lymph node-positive colon cancer do not see a medical oncologist and, thus, do not receive adjuvant chemotherapy. METHODS:To evaluate the role of the surgeon in determining referrals to medical oncology amo...

journal_title：Cancer

authors： Luo R,Giordano SH,Zhang DD,Freeman J,Goodwin JS

更新日期：2007-03-01 00:00:00

abstract：:A case of sinus histiocytosis with massive lymphadenopathy (SHML) in which cranial nerve function was impaired is described. Severe paraparesis due to an epidural block at the C2 and C5-T2 levels was also present. Treatment with cytotoxic agents resulted in a dramatic decrease in the size of the involved lymph nodes a...

journal_title：Cancer

authors： Haas RJ,Helmig MS,Prechtel K

更新日期：1978-07-01 00:00:00

abstract：BACKGROUND:The pretherapy prediction of occult lymph node involvement and the avoidance of otherwise futile and potentially morbid definitive local therapy is paramount in men with newly diagnosed prostate carcinoma. To identify patients with prostate carcinoma who likely have lymph node involvement and would benefit f...

journal_title：Cancer

authors： Polascik TJ,Manyak MJ,Haseman MK,Gurganus RT,Rogers B,Maguire RT,Partin AW

更新日期：1999-04-01 00:00:00

abstract：BACKGROUND:A retrospective clinicopathologic study was performed to identify the influence of diagnostic and therapeutic procedures on the outcomes of patients with the follicular variant of papillary thyroid carcinoma (FVPTC). METHODS:The results of 37 patients with FVPTC were compared with those of 37 randomly selec...

journal_title：Cancer

authors： Tielens ET,Sherman SI,Hruban RH,Ladenson PW

更新日期：1994-01-15 00:00:00

abstract：BACKGROUND:Case reports have associated neuroblastoma, a cancer derived from the embryonal neural crest, with aganglionosis coli and neurofibromatosis type I. The aim of the current study was to test the hypothesis that neuroblastoma is part of a global defect in neurodevelopment. METHODS:Neuropathologic findings from...

journal_title：Cancer

authors： Blatt J,Hamilton RL

更新日期：1998-04-15 00:00:00

abstract：:Tobacco use in the US is currently responsible for more than 30% of all cancer deaths, including cancers of the lung, larynx, oral cavity, pharynx, pancreas, kidney, bladder, and cervix. The lung cancer epidemic in men and then women since the turn of the century followed an increased prevalence of cigarette smoking. ...

journal_title：Cancer

authors： Ernster VL

更新日期：1988-10-15 00:00:00

abstract：BACKGROUND:The purpose of this study was to examine local definitive therapy for nonmetastatic breast cancer with the Patterns of Care Breast and Prostate Cancer (POCBP) study of the National Program of Cancer Registries (Centers for Disease Control and Prevention). METHODS:POCBP medical record data were re-abstracted...

journal_title：Cancer

authors： Anderson RT,Morris CR,Kimmick G,Trentham-Dietz A,Camacho F,Wu XC,Sabatino SA,Fleming ST,Lipscomb J

更新日期：2015-03-01 00:00:00

abstract：:Two consecutive trials for the treatment of childhood non-Hodgkin's lymphoma were evaluated, carried out by the same cooperative groups. Group A: From June, 1973 to December, 1975, 50 evaluable patients under 16 years of age participated in a study that included vincristine and prednisone plus surgery and/or radiother...

journal_title：Cancer

authors： Sackmann-Muriel F,Diez B,Schvartzman E,Braier JL,Schwartz L,Gallo G,Pavlovsky S

更新日期：1984-12-15 00:00:00

abstract：:Meningeal myeloid metaplasia (MM) is very rarely observed in patients with myelofibrosis. We report the occurrence of meningeal MM causing exophthalmus and fever in a patient with myelofibrosis secondary to polycythemia vera. A computerized tomography (CT) scan showed multiple intracranial and intraorbital enhancing m...

journal_title：Cancer

authors： Landolfi R,Colosimo C Jr,De Candia E,Castellana MA,De Cristofaro R,Trodella L,Leone G

更新日期：1988-12-01 00:00:00

abstract：BACKGROUND:The reliability of cytologic criteria to classify nonproliferative breast lesions (NPBL) is still debated. Sampling error and heterogeneity of breast lesions complicates the histologic correlation of fine-needle aspiration results further. METHODS:To provide optimal cytohistologic correlation, two smears (o...

journal_title：Cancer

authors： Sidawy MK,Tabbara SO,Bryan JA,Poprocky LA,Frost AR

更新日期：2001-04-25 00:00:00

abstract：:Based on laboratory studies showing enhanced cytotoxicity of floxuridine (FUDR) when used with high doses of leucovorin (LV), a pilot study of FUDR and LV through an implantable pump was initiated for the treatment of hepatic metastases from colorectal cancer. The highest dose of LV that could be administered, taking ...

journal_title：Cancer

authors： Kemeny N,Cohen A,Bertino JR,Sigurdson ER,Botet J,Oderman P

更新日期：1990-06-01 00:00:00

abstract：BACKGROUND:The objective of this study was to assess the rate and possible reasons for false-negative (FN) reflex human papillomavirus (HPV)-DNA tests. METHODS:The authors reviewed all ThinPrep cervical specimens that were submitted for reflex HPV-DNA testing using the Digene Hybrid Capture II (HC2) method from Januar...

journal_title：Cancer

authors： Eltoum IA,Chhieng DC,Crowe DR,Roberson J,Jin G,Broker TR

更新日期：2007-06-25 00:00:00