A human liposarcoma cell line producing hyaluronic acid.

abstract：:Computed tomography (CT) has emerged from the 1980s to play a dominant role in the pretreatment staging of renal and adrenal carcinomas. For detection, definition (staging), and determination of resectability or recurrence, CT with intravenous contrast enhancement, and more recently, magnetic resonance imaging (MRI) w...

journal_title：Cancer

authors： McClennan BL

更新日期：1991-02-15 00:00:00

abstract：:The clinical findings in 262 patients with melanoma were correlated with an assessment of their cellular-mediated immunity by delayed-type hypersensitivity (DTH) skin tests, by lymphocyte blastogenesis, and by leukocyte enumerations. Patients with systemic metastases (stage IV) and those with evidence of tumor burden ...

journal_title：Cancer

authors： Pritchard DJ,Ritts RE Jr,Taylor WF,Miller GC

更新日期：1978-06-01 00:00:00

abstract：:A new human extrahepatic bile duct carcinoma cell line (KMBC) was established from a serially transplanted tumor in nude mice that originated from a surgically resected tumor from a 73-year-old Japanese man; the cell line has been maintained for 5 five years. KMBC cells proliferate in a monolayered sheet with a popula...

journal_title：Cancer

authors： Yano H,Maruiwa M,Iemura A,Mizoguchi A,Kojiro M

更新日期：1992-04-01 00:00:00

abstract：BACKGROUND:The purpose of the study was to determine the utility of quantitation of the extracellular domain (ECD) of the HER-2/neu receptor in the serum for predicting response to treatment in patients with primary breast cancer receiving neoadjuvant therapy. METHODS:HER-2/neu ECD was measured in sera obtained from 3...

journal_title：Cancer

authors： Mazouni C,Hall A,Broglio K,Fritsche H,Andre F,Esteva FJ,Hortobagyi GN,Buzdar AU,Pusztai L,Cristofanilli M

更新日期：2007-02-01 00:00:00

abstract：BACKGROUND:In a previous phase 2 trial, axitinib was active and well tolerated in patients with advanced thyroid cancer. In this second phase 2 trial, the efficacy and safety of axitinib were evaluated further in this population, and pharmacokinetic/pharmacodynamic relationships and patient-reported outcomes were asses...

journal_title：Cancer

authors： Locati LD,Licitra L,Agate L,Ou SH,Boucher A,Jarzab B,Qin S,Kane MA,Wirth LJ,Chen C,Kim S,Ingrosso A,Pithavala YK,Bycott P,Cohen EE

更新日期：2014-09-01 00:00:00

abstract：:Irreversible and progressive renal parenchymal damage and functional impairment occurred in the majority of patients receiving at least six courses (200 mg/m2 of BCNU and/or methyl CCNU at eight-week intervals) of nitrosoureas for therapy of malignant brain tumors. Seventeen of 18 patients who received at least six co...

journal_title：Cancer

authors： Schacht RG,Feiner HD,Gallo GR,Lieberman A,Baldwin DS

更新日期：1981-09-15 00:00:00

abstract：:Pel-Epstein fever cycles, consisting of 1-2 weeks of high fever separated by afebrile periods of the same duration, are classically characteristic of Hodgkin's disease. Clinical observation has determined that the lymph nodes enlarge during periods of fever and reduce in size as the fever subsides. To our knowledge, t...

journal_title：Cancer

authors： Scanlon GT,Castellino RA,Rudders R

更新日期：1975-12-01 00:00:00

abstract：:Among the patients showing evidence of cerebral metastases without previously known cancer history, lung cancer has been found 37 times as the primary tumor in our institution. There were 34 men and three women and all but two were heavy smokers. Only one presented at diagnosis with thoracic symptoms but the chest rad...

journal_title：Cancer

authors： Trillet V,Catajar JF,Croisile B,Turjman F,Aimard G,Bourrat C,Bret P,Carrie C,Chassard JL,Chauvin F

更新日期：1991-06-01 00:00:00

abstract：:Two female patients with desmoid tumors (aggressive fibromatosis) showed tumor regression after endocrine therapy. In one patient, tumor response to tamoxifen has been maintained over several years of treatment. In the second patient, who had inoperable mesenteric fibromatosis, the tumor progressed on tamoxifen but re...

journal_title：Cancer

authors： Wilcken N,Tattersall MH

更新日期：1991-09-15 00:00:00

abstract：:Results of cytogenetic studies of a patient with acute granulocytic leukemia are described. The modal number of chromosomes in cells from bone marrow samples was 43; the karyotype was characterized by missing chromosomes in groups B, C, and E. According to successive studies of the same metaphases by fluorescent stain...

journal_title：Cancer

authors： Sofuni T,Okada H

更新日期：1975-02-01 00:00:00

abstract：BACKGROUND:A hypothesis generated a retrospective analysis of the improvement of survival over time in patients with cutaneous melanoma (CM) in order to identify factors contributing to this progress. METHODS:A cohort of 4791 patients diagnosed with primary CM in southern Germany between 1976 and 2001 was analyzed. Ka...

journal_title：Cancer

authors： Lasithiotakis KG,Leiter U,Eigentler T,Breuninger H,Metzler G,Meier F,Garbe C

更新日期：2007-03-15 00:00:00

abstract：BACKGROUND:It remains unclear whether primary tumor resection benefits patients with metastatic neuroblastoma. The authors assessed the impact of extent and timing of resection on outcome in these patients. METHODS:The authors reviewed the records of 124 patients > 1 year of age at diagnosis of International Neuroblas...

journal_title：Cancer

authors： McGregor LM,Rao BN,Davidoff AM,Billups CA,Hongeng S,Santana VM,Hill DA,Fuller C,Furman WL

更新日期：2005-12-15 00:00:00

abstract：:Melanomas of the choroid, ciliary body, and iris of the eye are collectively known as uveal melanomas. These cancers represent 5% of all melanoma diagnoses in the United States, and their age-adjusted risk is 5 per 1 million population. These less frequent melanomas are dissimilar to their more common cutaneous melano...

journal_title：Cancer

authors： Chattopadhyay C,Kim DW,Gombos DS,Oba J,Qin Y,Williams MD,Esmaeli B,Grimm EA,Wargo JA,Woodman SE,Patel SP

更新日期：2016-08-01 00:00:00

abstract：BACKGROUND:The results of an international, multicenter, randomized, double-blind, controlled study assessing the efficacy and safety of lenalidomide treatment in patients with refractory stage IV metastatic malignant melanoma are reported. METHODS:The study compared treatment with lenalidomide (25 mg/d on Days 1-21 o...

journal_title：Cancer

authors： Eisen T,Trefzer U,Hamilton A,Hersey P,Millward M,Knight RD,Jungnelius JU,Glaspy J

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Ovarian cancer patients frequently receive chemotherapy near the end of life. The purpose of the current study was to develop indicators that characterize those ovarian cancer patients who have a short life span. METHODS:The medical charts of deceased epithelial ovarian cancer patients were retrospectively ...

journal_title：Cancer

authors： von Gruenigen V,Daly B,Gibbons H,Hutchins J,Green A

更新日期：2008-05-15 00:00:00

abstract：BACKGROUND:Patient safety is a critical concern in clinical oncology, but the ability to measure adverse events (AEs) across cancer care is limited by a narrow focus on treatment-related toxicities. The objective of this study was to assess the nature and extent of AEs among cancer patients across inpatient and outpati...

journal_title：Cancer

authors： Lipitz-Snyderman A,Pfister D,Classen D,Atoria CL,Killen A,Epstein AS,Anderson C,Fortier E,Weingart SN

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:Gastric carcinoma with lymphoid stroma (GCLS) has been reported to have a more favorable prognosis than ordinary gastric carcinoma, however, the precise mechanism of the pathogenesis for GCLS remains unclear. METHODS:The authors analyzed 99 GCLS in 94 patients for Epstein-Barr virus (EBV) sequences using po...

journal_title：Cancer

authors： Nakamura S,Ueki T,Yao T,Ueyama T,Tsuneyoshi M

更新日期：1994-05-01 00:00:00

abstract：:Various attempts have been made to improve the effectiveness of radiation in the treatment of cerebral malignant astrocytomas. A trend favoring multiple daily fractionated (MDF) radiation therapy over conventional single daily fractionated (CF) radiation therapy was identified in our previous study. In order to assess...

journal_title：Cancer

authors： Shin KH,Urtasun RC,Fulton D,Geggie PH,Tanasichuk H,Thomas H,Muller PJ,Curry B,Mielke B,Johnson E

更新日期：1985-08-15 00:00:00

abstract：:The possibility that urinary pepsinogen I is a tumor marker of stomach cancer after total gastrectomy was examined. To decide the cutoff level of urinary pepsinogen I after total gastrectomy, urine samples from 15 patients who had undergone total gastrectomy for stomach cancer in the early or advanced stages and had b...

journal_title：Cancer

authors： Yamaguchi T,Takahashi T,Yokota T,Kitamura K,Noguchi A,Kamiguchi M,Doi M,Ahn T,Sawai K,Yamane T

更新日期：1991-08-15 00:00:00

abstract：:The introduction of trimodal combination therapy (surgery + radiation + intraarterial infusion) for maxillary carcinoma resulted in a change in the sites of recurrence and no satisfactory improvement in the local control rate. To examine the cause of these phenomena, external carotid angiography was performed on 51 pa...

journal_title：Cancer

authors： Shibuya H,Suzuki S,Horiuchi J,Takagi M,Okuyama T,Suzuki H,Takeda M

更新日期：1982-12-15 00:00:00

abstract：BACKGROUND:According to the overview of Early Breast Cancer Trialists' Collaborative Group, anthracycline containing regimens are superior to cyclophosphamide, methotrexate, and 5-fluorouracil (CMF) as adjuvant chemotherapy for breast carcinoma, but no comparative information is available in terms of primary chemothera...

journal_title：Cancer

authors： Cocconi G,Di Blasio B,Boni C,Bisagni G,Ceci G,Rondini E,Bella M,Leonardi F,Savoldi L,Camisa R,Bruzzi P

更新日期：2002-07-15 00:00:00

abstract：:A case of meningeal melanocytoma of the left Meckel's cave associated with ipsilateral Ota's nevus in a 43-year-old woman, was studied by light and electron microscopy. The cells of the tumor were characterized by the presence of dendritic cytoplasmic processes, melanosomes and premelanosomes; hence, they were deemed ...

journal_title：Cancer

authors： Botticelli AR,Villani M,Angiari P,Peserico L

更新日期：1983-06-15 00:00:00

abstract：BACKGROUND:Human breast cancers frequently show loss of heterozygosity (LOH) and/or amplification at specific chromosomal regions. METHODS:To investigate the roles of these genetic alterations during tumor development and/or progression, 457 cases of primary breast cancer were examined for LOH at chromosomal regions 1...

journal_title：Cancer

authors： Harada Y,Katagiri T,Ito I,Akiyama F,Sakamoto G,Kasumi F,Nakamura Y,Emi M

更新日期：1994-10-15 00:00:00

abstract：:Pain management often is difficult in patients with bone metastases. Metastatic disease represents >40% of oncologic practice, and >70% of patients with metastatic disease have uncontrolled cancer-related pain. Significant morbidity caused by pathologic fracture and spinal cord compression can result from untreated bo...

journal_title：Cancer

authors： Janjan NA

更新日期：1997-10-15 00:00:00

abstract：:A primitive neuroectodermal tumor of peripheral nerve origin was examined by light and electron microscopy. The lesion arose in association with the S1 nerve root of the lumbosacral plexus in a 22-year-old female. Following a surgical biopsy, the patient received systemic chemotherapy; however, approximately one-and-a...

journal_title：Cancer

authors： Bolen JW,Thorning D

更新日期：1980-12-01 00:00:00

abstract：BACKGROUND:Insulin-like growth factor I (IGF-I) is a potent mitogen for breast cancer cells. The majority of IGF-I in plasma is bound to IGF binding proteins (IGFBPs), which modulate the biologic effects of IGF-I. METHODS:Plasma concentrations of IGF-I, IGFBP-I, and IGFBP-3 were compared between 40 postmenopausal brea...

journal_title：Cancer

authors： Lahti EI,Knip M,Laatikainen TJ

更新日期：1994-07-15 00:00:00

abstract：BACKGROUND:The advantage of whole-body imaging for distribution studies is that it accounts for all activities. The problem, however, is that the classic approach to determining distribution from planar images does not accommodate overlapping structures. That approach assumes implicitly that the sampling region is a pr...

journal_title：Cancer

authors： Goris ML,Knox SA,Nielsen KR,Bouillant O

更新日期：1994-02-01 00:00:00

abstract：BACKGROUND:Some studies have suggested that women with metastatic malignant melanoma have a better survival rate than men. However, little is known about the effect of gender on survival in combination with other clinical variables and treatment variables. Thus, an analysis of 813 eligible patients from 15 consecutive ...

journal_title：Cancer

authors： Unger JM,Flaherty LE,Liu PY,Albain KS,Sondak VK

更新日期：2001-03-15 00:00:00

abstract：BACKGROUND:Increased pretreatment serum interleukin (IL)-6 levels among patients with head and neck squamous cell carcinoma (HNSCC) have been shown to correlate with poor prognosis, but sample sizes in prior studies have been small and thus unable to control for other known prognostic variables. METHODS:A longitudinal...

journal_title：Cancer

authors： Duffy SA,Taylor JM,Terrell JE,Islam M,Li Y,Fowler KE,Wolf GT,Teknos TN

更新日期：2008-08-15 00:00:00

abstract：:We counted the number of toluidine blue positive mast cells within and around the tumor in 44 patients with soft tissue sarcomas (STS). Irrespective of their histologic types, these cases were broadly divided into the following two groups: (1) low count (less than 20 mast cells/10 high-power fields [HPF]) and (2) high...

journal_title：Cancer

authors： Ueda T,Aozasa K,Tsujimoto M,Yoshikawa H,Kato T,Ono K,Matsumoto K

更新日期：1988-12-01 00:00:00