Gender and other survival predictors in patients with metastatic melanoma on Southwest Oncology Group trials.

abstract：BACKGROUND:Primary malignant splenic neoplasms are rare tumors. Apart from involvement of the spleen by malignant lymphoma, hemangiosarcoma is the most common form of primary malignant neoplasm in the spleen. The diagnosis often is made at autopsy or after spontaneous splenic rupture. The prognosis is usually poor, and...

journal_title：Cancer

authors： Søndenaa K,Heikkilä R,Nysted A,Søreide JA,Odegaard H,Pollard ML,Holter J

更新日期：1993-01-01 00:00:00

abstract：:The use of prostate-specific antigen (PSA) as a screening test remains controversial. There have been several attempts to refine PSA measurements to improve its predictive value. These modifications, including PSA density, PSA kinetics, and the measurement of PSA isoforms, have met with limited success. Therefore, com...

journal_title：Cancer

authors： Herman MP,Dorsey P,John M,Patel N,Leung R,Tewari A

更新日期：2009-07-01 00:00:00

abstract：:The concept of second-look surgery was introduced by Wangensteen 25 years ago, and 17% of patients were reported to be converted to a cancer-free state. Instead of an arbitrary time interval for reoperation, serial CEA values were used as the indicator of colon cancer recurrence and second-look operation. Twenty-two r...

journal_title：Cancer

authors： Minton JP,Martin EW Jr

更新日期：1978-09-01 00:00:00

abstract：BACKGROUND:BRCA2 gene, located at chromosome 13q12.3, frequently is altered in familial types of cancer in which a "double-hit" inactivation model seems to occur. In contrast, in sporadic forms of cancer there is frequent absence of a second event (point mutations) suggesting that allelic imbalance at the BRCA2 locus m...

journal_title：Cancer

authors： Gorgoulis VG,Kotsinas A,Zacharatos P,Mariatos G,Liloglou T,Tsoli E,Kokotas S,Fassoulas C,Field JK,Kittas C

更新日期：2000-11-01 00:00:00

abstract：BACKGROUND:The authors reviewed changes in the initial clinical presentation, management techniques, and patterns of disease recurrence over time (1981-1996) in patients with breast carcinoma treated with breast-conserving therapy (BCT) at a single institution. The goals of the current study were to determine the frequ...

journal_title：Cancer

authors： Pass H,Vicini FA,Kestin LL,Goldstein NS,Decker D,Pettinga J,Ingold J,Benitez P,Neumann K,Rebner M,Dekhne N,Martinez A

更新日期：2004-08-15 00:00:00

abstract：BACKGROUND:Survival trends provide a measure of improvement in detection and treatment over time. In the current study, updated childhood and adolescent cancer survival statistics are presented, overall and among demographic subgroups, including Hispanics, for whom to the authors' knowledge national rates have not been...

journal_title：Cancer

authors： Linabery AM,Ross JA

更新日期：2008-11-01 00:00:00

abstract：BACKGROUND:Synovial sarcoma usually arises in the extremities and in close proximity to large joints. Reported examples arising in the anterior abdominal wall are rare. Because most accounts from this location consist of case reports, neither clinical nor prognostic features have been well delineated. METHODS:Twenty-s...

journal_title：Cancer

authors： Fetsch JF,Meis JM

更新日期：1993-07-15 00:00:00

abstract：BACKGROUND:Adenosquamous/squamous cell carcinoma of the gallbladder generally has been considered a lethal disease. The objective of this study was to clarify the effectiveness of resection for patients with adenosquamous/squamous cell carcinoma of the gallbladder. METHODS:Twenty-nine patients who underwent resection ...

journal_title：Cancer

authors： Oohashi Y,Shirai Y,Wakai T,Nagakura S,Watanabe H,Hatakeyama K

更新日期：2002-06-01 00:00:00

abstract：BACKGROUND:Brain metastases from esophageal carcinoma are extremely rare, and information regarding the natural history, results of treatment, and possible prognostic factors in these patients is limited. METHODS:The records of 36 patients with brain metastases from esophageal carcinoma who were treated between 1986 a...

journal_title：Cancer

authors： Ogawa K,Toita T,Sueyama H,Fuwa N,Kakinohana Y,Kamata M,Adachi G,Saito A,Yoshii Y,Murayama S

更新日期：2002-02-01 00:00:00

abstract：BACKGROUND:Despite growing evidence and support for shared decision making, little is known about the experiences of parents who hold more active roles than they wish. METHODS:This was a prospective cohort study of 372 parents of children with cancer and their oncologists at 2 academic pediatric hospitals. Parents wer...

journal_title：Cancer

authors： Sisk BA,Kang TI,Goldstein R,DuBois JM,Mack JW

更新日期：2019-04-15 00:00:00

abstract：BACKGROUND:Seminal vesicle (SV) invasion at the time of radical prostatectomy (RP) generally is considered to be indicative of poor outcome. The authors examined whether there was a subset of men with SV invasion who had long-term prostate-specific antigen (PSA) progression-free survival. METHODS:Data were examined fr...

journal_title：Cancer

authors： Freedland SJ,Aronson WJ,Presti JC Jr,Amling CL,Terris MK,Trock B,Kane CJ

更新日期：2004-04-15 00:00:00

abstract：:Demonstration of malignant cells in blood specimens collected during transurethral resection of the prostate (TURP) has implicated TURP in the dissemination of prostatic cancer. Of 153 patients who underwent radiation therapy for prostate cancer between January 1977 and June 1990 and were retrospectively analyzed, 93 ...

journal_title：Cancer

authors： Pansadoro V,Sternberg CN,DePaula F,Florio A,Giannarelli D,Arcangeli G

更新日期：1991-11-01 00:00:00

abstract：:A primary cardiac spindle cell tumor with immunoreactivity for keratin proteins is reported. Cytogenetic analysis of the tumor demonstrated a translocation (X;18), an aberration almost exclusively reported in synovial sarcomas. Postmortem examination revealed amphibole asbestos within the lungs and diaphragmatic pleur...

journal_title：Cancer

authors： Karn CM,Socinski MA,Fletcher JA,Corson JM,Craighead JE

更新日期：1994-01-01 00:00:00

abstract：:Chondrosarcoma of the foot is a very unusual entity. A case arising from a solitary osteocartilagenous exostosis is presented and the literature is reviewed and discussed. ...

journal_title：Cancer

authors： Lewis MM,Marcove RC,Bullough PG

更新日期：1975-08-01 00:00:00

abstract：BACKGROUND:Quantified, human hemoglobin (Hb)-specific, immunochemical fecal occult blood test (IFOBT) measurements are now used for colorectal cancer (CRC) screening. The objective was to evaluate sensitivity and specificity for CRC and advanced adenomatous polyps (APs) by the fecal Hb threshold used to determine a pos...

journal_title：Cancer

authors： Rozen P,Comaneshter D,Levi Z,Hazazi R,Vilkin A,Maoz E,Birkenfeld S,Niv Y

更新日期：2010-05-01 00:00:00

abstract：BACKGROUND:The regulation of parathyroid hormone-related protein (PTH-rP) mRNA levels and immunoreactive (ir)PTH-rP formation by peptide growth factors, particularly transforming growth factor-beta (TGF-beta) and epidermal growth factor (EGF), in squamous cell carcinomas of gynecologic origin is largely unknown. METHO...

journal_title：Cancer

authors： Tait DL,MacDonald PC,Casey ML

更新日期：1994-03-01 00:00:00

abstract：BACKGROUND:In colorectal carcinoma, venous invasion has been related to patient survival. Liver metastasis develops more frequently when venous invasion is present. However, the histologic features and clinical significance of venous invasion are not well understood. METHODS:A histologic study of venous invasion in co...

journal_title：Cancer

authors： Ouchi K,Sugawara T,Ono H,Fujiya T,Kamiyama Y,Kakugawa Y,Mikuni J,Tateno H

更新日期：1996-12-01 00:00:00

abstract：BACKGROUND:A series of retrospective studies have reported that patients with human epidermal growth factor receptor 2(HER2)-positive breast cancer are at a greater risk of central nervous system (CNS) metastases. Trastuzumab, which does not cross the blood-brain barrier, has been associated with this increased risk. ...

journal_title：Cancer

authors： Musolino A,Ciccolallo L,Panebianco M,Fontana E,Zanoni D,Bozzetti C,Michiara M,Silini EM,Ardizzoni A

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND:Recent clinical studies have demonstrated that tumor angiogenesis is a potent prognostic indicator for breast cancer patients. The quantitation of endothelial growth factors is thought to be useful to assess angiogenic phenotype in the tumor. Among the many new endothelial growth factors, vascular endothelia...

journal_title：Cancer

authors： Toi M,Kondo S,Suzuki H,Yamamoto Y,Inada K,Imazawa T,Taniguchi T,Tominaga T

更新日期：1996-03-15 00:00:00

abstract：BACKGROUND:The current randomized, controlled, multicenter clinical trial was conducted to investigate the efficacy of concurrent neoadjuvant chemotherapy (NCT) and estrogen deprivation in patients with estrogen receptor (ER)-positive, human epidermal growth factor receptor 2 (HER2)-negative breast cancer. METHODS:Eli...

journal_title：Cancer

authors： Yu KD,Wu SY,Liu GY,Wu J,Di GH,Hu Z,Hou YF,Chen CM,Fan L,Tang LC,Shen ZZ,Wu KJ,Zhuang ZG,Zhang HW,Shao ZM

更新日期：2019-07-01 00:00:00

abstract：:Doubling times were estimated for 15 breast carcinomas in 13 patients, and were found to be between 42 and 397 days with the average at 211 days. The mean lead time at mean growth rate from the average size of 44 preclinical to the average size of 118 clinical tumors was estimated to be 3 years. This period may be con...

journal_title：Cancer

authors： Lundgren B

更新日期：1977-10-01 00:00:00

abstract：BACKGROUND:The incidence and pattern of brain metastases was analyzed among patients who achieved a pathological complete response (pCR) after neoadjuvant chemotherapy or chemoradiotherapy for locally advanced nonsmall-cell lung cancer (NSCLC). METHODS:Between 1990 and 2004, 211 patients were treated with neoadjuvant ...

journal_title：Cancer

authors： Chen AM,Jahan TM,Jablons DM,Garcia J,Larson DA

更新日期：2007-04-15 00:00:00

abstract：:The effect of cis-diamminedichloroplatinum II (DDP) and ionizing radiation on human bladder transitional cell carcinoma (TCC) was evaluated in nude mouse-grown human tumors following administration of single-agent and combination treatment. Combination of DDP and radiation resulted in accelerated tumor regression and ...

journal_title：Cancer

authors： Kyriazis AP,Yagoda A,Kereiakes JG,Kyriazis AA,Whitmore WF Jr

更新日期：1983-08-01 00:00:00

abstract：:Eighty-seven previously untreated patients with pathologic Stage IA, II (A or B), or IIIA Hodgkin's disease were randomized over a 48-month period to receive either megavoltage extended field radiotherapy alone or megavoltage radiotherapy limited to involved lymph node sites (including at least an upper mantle field) ...

journal_title：Cancer

authors： O'Connell MJ,Wiernik PH,Brace KC,Byhardt RW,Greene WH

更新日期：1975-04-01 00:00:00

abstract：BACKGROUND:: Survival rates for gastrointestinal (GI) and bronchopulmonary (BP) neuroendocrine tumors (NETs) have not altered significantly (5-year survival rate: GI NETs, 64.1%; BP NETs, 87%-89%) in 30 years (from 1973 to 2004). No effective or specific antineoplastic agents are available to date, although somatostati...

journal_title：Cancer

authors： Drozdov I,Kidd M,Gustafsson BI,Svejda B,Joseph R,Pfragner R,Modlin IM

更新日期：2009-11-01 00:00:00

abstract：BACKGROUND:Multimodality treatment has dramatically improved the outcome of patients with Ewing sarcoma. However, there appears to be little information concerning treatment-related complications in patients who are long-term survivors. METHODS:Forty-one patients with Ewing sarcoma who were treated between 1960-1980 a...

journal_title：Cancer

authors： Fuchs B,Valenzuela RG,Inwards C,Sim FH,Rock MG

更新日期：2003-12-15 00:00:00

abstract：BACKGROUND:The incidence of basal cell carcinoma (BCC) in a defined population is unknown. METHODS:The incidence of histologically diagnosed cases of BCC in a defined population of a city in southern Sweden was studied. Four 2-year periods were examined from 1970 to 1986. Cases from 1970 and 1980 were reexamined micro...

journal_title：Cancer

authors： Dahl E,Aberg M,Rausing A,Rausing EL

更新日期：1992-07-01 00:00:00

abstract：BACKGROUND:Although it induces a relevant reduction in the risk of both visceral metastases and locoregional recurrences, the combination of chemotherapy and surgery only marginally improves the survival of patients with Stage IIIA(N2) (International Union Against Cancer staging and classification system) nonsmall-cell...

journal_title：Cancer

authors： Andre F,Grunenwald D,Pujol JL,Girard P,Dujon A,Brouchet L,Brichon PY,Westeel V,Le Chevalier T

更新日期：2001-06-15 00:00:00

abstract：BACKGROUND:Because medulloblastoma (MB) is rare in adults, the few studies on this condition have been retrospective, and the follow-up has tended to be short. Furthermore, the different therapeutic strategies used in these patients has made it difficult to assess survival rates and prognostic factors. METHODS:In 1989...

journal_title：Cancer

authors： Brandes AA,Franceschi E,Tosoni A,Blatt V,Ermani M

更新日期：2007-11-01 00:00:00

abstract：BACKGROUND:The induction of estrogen and progesterone receptors (ER and PGR) has been reported in breast and endometrial cancer cells exposed to human fibroblast interferon-beta (hIFN-beta). Clinical verification of this finding might provide the rationale for new therapeutic approaches. This study was designed to eval...

journal_title：Cancer

authors： Codegoni AM,Landoni F,Lomonico S,Losa G,Mangioni C,Taverna M,Lucchini V,D'Incalci M

更新日期：1996-08-01 00:00:00