Autoradiographic and fluorescent staining studies of bone marrow chromosomes from a patient with acute granulocytic leukemia.

abstract：:In order to determine whether the use of a sequence of chemotherapeutic regimens plus BCG could produce longer durations of remission in adult acute nonlymphocytic leukemia than maintenance therapy with cytosine arabinoside, 6-thioguanine, plus BCG, a randomized study was performed at Washington University. Upon achie...

journal_title：Cancer

authors： Presant CA,Berger NA,Klahr C,Phillips GL

更新日期：1980-07-01 00:00:00

abstract：:The authors describe two cases of epithelioid sarcoma of the vulva and summarize the clinical and pathologic experience with this vulvar neoplasm. Findings indicate that epithelioid sarcoma of the vulva usually occurs in the labia majora of young women, but may occur in later life. Clinically it may mimic a Bartholin'...

journal_title：Cancer

authors： Ulbright TM,Brokaw SA,Stehman FB,Roth LM

更新日期：1983-10-15 00:00:00

abstract：BACKGROUND:The objective of this study was to define the effects of socioeconomic status (SES) and other demographic variables on outcomes for patients with pancreatic adenocarcinoma. METHODS:Florida cancer registry and inpatient hospital data were queried for pancreatic adenocarcinoma diagnosed from 1998 to 2002. RE...

journal_title：Cancer

authors： Cheung MC,Yang R,Byrne MM,Solorzano CC,Nakeeb A,Koniaris LG

更新日期：2010-02-01 00:00:00

abstract：BACKGROUND:Flow cytometric analysis of trophoblastic tissue has shown that most partial hydatidiform moles (PMs) are triploid, whereas most complete moles (CMs) are diploid or tetraploid. Ploidy analysis can support a diagnosis of CM or PM. However, in some cases, a precise diagnosis cannot be rendered. METHODS:This s...

journal_title：Cancer

authors： Bocklage TJ,Smith HO,Bartow SA

更新日期：1994-06-01 00:00:00

abstract：:Based on the independent activity of cisplatin, vinblastine, and dimethyl-triazeno-imidazole-carboxamide (DTIC) (CVD), a combination of these agents was used in the treatment of patients with advanced melanoma. Vinblastine was used in a dose of 1.6 mg/m2/d for 5 days, DTIC was used in a dose of 800 mg/m2 intravenously...

journal_title：Cancer

authors： Legha SS,Ring S,Papadopoulos N,Plager C,Chawla S,Benjamin R

更新日期：1989-11-15 00:00:00

abstract：BACKGROUND:Complementary medicine has become an important aspect of palliative cancer care. This overview is primarily aimed at providing guidance to clinicians regarding some commonly used complementary therapies. METHODS:Several complementary therapies were identified as particularly relevant to palliative cancer ca...

journal_title：Cancer

authors： Ernst E

更新日期：2001-06-01 00:00:00

abstract：BACKGROUND:Transforming growth factor beta (TGFbeta) is important in colorectal cancer (CRC) progression. Bone morphogenetic proteins (BMPs), a subgroup within the TGFbeta superfamily, recently also have been implicated in CRC, but their precise role in CRC has yet to be investigated. METHODS:The authors used a tissue...

journal_title：Cancer

authors： Kodach LL,Bleuming SA,Musler AR,Peppelenbosch MP,Hommes DW,van den Brink GR,van Noesel CJ,Offerhaus GJ,Hardwick JC

更新日期：2008-01-15 00:00:00

abstract：:Between February 1980 and December 1985, splenectomies were performed in 13 patients with advanced (Stage III and IV) chronic lymphocytic leukemia (CLL). Patients had advanced disease for a median of 32 months at the time of splenectomy and all were refractory to chemotherapy. All patients were anemic with a median he...

journal_title：Cancer

authors： Stein RS,Weikert D,Reynolds V,Greer JP,Flexner JM

更新日期：1987-05-15 00:00:00

abstract：:Two cases are reported of patients who developed a hematologic malignancy several years after intravesical chemotherapy of superficial bladder cancer with etoglucid, doxorubicin, and mitomycin C. In one patient, karyotypic abnormalities (-5, 7q-) typical of a therapy induced malignancy were associated with rapid progr...

journal_title：Cancer

authors： Sonneveld P,Kurth KH,Hagemeyer A,Abels J

更新日期：1990-01-01 00:00:00

abstract：BACKGROUND:Pediatric rhabdomyosarcomas (RMS) have a more advantageous prognosis after multimodality treatment compared with adult RMS, which might be related to a decreased sensitivity to chemotherapy in adults. Resistance to chemotherapy might be conveyed by the multidrug resistance (MDR)-associated proteins P-glycopr...

journal_title：Cancer

authors： Komdeur R,Klunder J,van der Graaf WT,van den Berg E,de Bont ES,Hoekstra HJ,Molenaar WM

更新日期：2003-04-15 00:00:00

abstract：BACKGROUND:Granulocyte-macrophage-colony stimulating factor (GM-CSF) administration stimulates the proliferation of hemopoietic progenitors. Shortly (48-96 hours) after its discontinuation, feedback phenomena occur and the progenitor proliferation rate drops below baseline levels. As the quiescence of hyperplastic bone...

journal_title：Cancer

authors： Aglietta M,Montemurro F,Fagioli F,Volta C,Botto B,Cantonetti M,Racanelli V,Teofili L,Ferrara R,Amadori S,Castoldi GL,Dammacco F,Levis A

更新日期：2000-01-15 00:00:00

abstract：:Flow cytometry (FC) analysis including DNA index (ploidy status) and cell kinetics (%S and %S + G2/M) was done on frozen tissue of the primary lesions of 101 women with node negative (N-) breast cancer who were studied prospectively. Currently, 19% (19/101) of the patients have recurred. No significant relations have ...

journal_title：Cancer

authors： Muss HB,Kute TE,Case LD,Smith LR,Booher C,Long R,Kammire L,Gregory B,Brockschmidt JK

更新日期：1989-11-01 00:00:00

abstract：:Estrogen and progesterone receptors (ER/PR) were measured in primary tumors and metastases of 397 breast cancer patients. Survival following mastectomy was significantly longer in patients with ER and PR positive tumors, as was survival after first recurrence. The prognostic value of ER and PR was compared with such c...

journal_title：Cancer

authors： Alanko A,Heinonen E,Scheinin T,Tolppanen EM,Vihko R

更新日期：1985-10-01 00:00:00

abstract：:A primitive neuroectodermal tumor of peripheral nerve origin was examined by light and electron microscopy. The lesion arose in association with the S1 nerve root of the lumbosacral plexus in a 22-year-old female. Following a surgical biopsy, the patient received systemic chemotherapy; however, approximately one-and-a...

journal_title：Cancer

authors： Bolen JW,Thorning D

更新日期：1980-12-01 00:00:00

abstract：:A tumor colony assay (TCA) was evaluated for its ability to predict anticancer drug responses in an N-[4-(5-nitro-2-furyl)-2-thiazolyl]-formamide (FANFT)-induced murine bladder tumor (MBT) model. Ten anticancer drugs were evaluated in vivo and in vitro using four MBT cell lines (40 drug responses). Using the optimum c...

journal_title：Cancer

authors： Niell HB,Soloway MS,Wood CA,McCallum LW,Webster K

更新日期：1983-08-15 00:00:00

abstract：BACKGROUND:Hereditary nonpolyposis colorectal cancer (HNPCC or Lynch syndrome) is an autosomal dominant disease characterized by early-onset intestinal neoplasms, localization of tumors in the proximal colon, and frequent association with cancers at other sites, especially the endometrium, skin, and stomach. The identi...

journal_title：Cancer

authors： Ponz de Leon M,Sassatelli R,Benatti P,Roncucci L

更新日期：1993-06-01 00:00:00

abstract：BACKGROUND:The current study was conducted to characterize the epidemiology, histology, and radiographic features of as well as the surgical approach to pediatric and adolescent renal cell carcinoma (pRCC). METHODS:pRCC cases prospectively enrolled on the Children's Oncology Group study AREN03B2 underwent central path...

journal_title：Cancer

authors： Geller JI,Ehrlich PF,Cost NG,Khanna G,Mullen EA,Gratias EJ,Naranjo A,Dome JS,Perlman EJ

更新日期：2015-07-15 00:00:00

abstract：:Between the years 1973-1977, 152 male patients from 28 participating Veterans Hospitals with histologically proven nonresectable cancer of the pancreas were randomized in a two-arm study. The treated group was to receive combination chemotherapy with 5-FU and CCNU, and the controls were to receive no chemotherapy. Bot...

journal_title：Cancer

authors： Frey C,Twomey P,Keehn R,Elliott D,Higgins G

更新日期：1981-01-01 00:00:00

abstract：BACKGROUND:The authors administered a combination of docetaxel and topotecan with granulocyte-colony-stimulating factor (G-CSF) support in a Phase I study to define the maximum tolerated dose (MTD) of this regimen. METHODS:Patients with advanced-stage solid tumors were eligible for this trial if they had a Zubrod perf...

journal_title：Cancer

authors： Tsao AS,Shin DM,Palmer JL,Lee JS,Glisson BS

更新日期：2004-05-15 00:00:00

abstract：:With nearly 80% of childhood cancer patients achieving cure, there are more adult survivors living now than at any other time in history. Because they are at risk for developing complications of treatment years later, it is recommended that survivors undergo systematic, regular monitoring into young adulthood and beyo...

journal_title：Cancer

authors： Freyer DR,Kibrick-Lazear R

更新日期：2006-10-01 00:00:00

abstract：:A total of 1026 patients with gastric cancer was followed up for five years after surgery and classified into different groups according to surgeons' assessment of nodal involvement, serosal invasion, peritoneal spread, and hepatic metastasis. The survival of each group was studied by parametric analysis, using the lo...

journal_title：Cancer

authors： Maetani S,Tobe T,Hirakawa A,Kashiwara S,Kuramoto S

更新日期：1980-12-15 00:00:00

abstract：BACKGROUND:: Although platinum-based combinations are considered the best option of care for patients with advanced nonsmall cell lung cancer (NSCLC), single-agent therapy is the preferred treatment for older patients. Since the late 1990s, various combinations of third-generation agents (gemcitabine [G], vinorelbine, ...

journal_title：Cancer

authors： Russo A,Rizzo S,Fulfaro F,Adamo V,Santini D,Vincenzi B,Gebbia N,Carreca I

更新日期：2009-05-01 00:00:00

abstract：BACKGROUND:Although it induces a relevant reduction in the risk of both visceral metastases and locoregional recurrences, the combination of chemotherapy and surgery only marginally improves the survival of patients with Stage IIIA(N2) (International Union Against Cancer staging and classification system) nonsmall-cell...

journal_title：Cancer

authors： Andre F,Grunenwald D,Pujol JL,Girard P,Dujon A,Brouchet L,Brichon PY,Westeel V,Le Chevalier T

更新日期：2001-06-15 00:00:00

abstract：BACKGROUND:Hyperglycemia is often observed in medically ill patients. Previous studies have shown that patients with hyperglycemia during induction therapy for acute lymphoblastic leukemia develop more infections and have shorter disease-free survival. The authors hypothesized that hyperglycemia may be associated with ...

journal_title：Cancer

authors： Ali NA,O'Brien JM Jr,Blum W,Byrd JC,Klisovic RB,Marcucci G,Phillips G,Marsh CB,Lemeshow S,Grever MR

更新日期：2007-07-01 00:00:00

abstract：BACKGROUND:Previous studies in the literature have suggested that radiolabeled F(ab')2 fragments might be superior to whole immunoglobulin G (IgG) for imaging and therapy of cancer because of their greater penetration in tumors. To test this hypothesis, the authors compared tumor and normal tissue uptake along with pla...

journal_title：Cancer

authors： Murray JL,Rosenblum MG,Zhang HZ,Podoloff DA,Kasi LP,Curley SA,Chan JC,Roh M,Hohn DC,Brewer H

更新日期：1994-02-01 00:00:00

abstract：:Patients with cancer experience a much higher than expected incidence of thromboembolic disorders, commonly referred as Trousseau syndrome. Although this association has been well documented, the etiology of the hypercoagulable state is not known. The expression on tumor cells of tissue factor (TF), a membrane-bound l...

journal_title：Cancer

authors： Callander NS,Varki N,Rao LV

更新日期：1992-09-01 00:00:00

abstract：:Hypercalcemia is very uncommon in small cell (oat cell) carcinoma of the lung. Two cases of this neoplasm associated with symptomatic hypercalcemia are described. Despite normal skeletal roentgenograms, metastatic bone disease was demonstrated by abnormal bone scans and bone biopsies in both patients. The combination ...

journal_title：Cancer

authors： Bowman DM,Dubé WJ,Levitt M

更新日期：1975-09-01 00:00:00

abstract：BACKGROUND:The authors conducted a comprehensive review of the efficacy of 2-deoxy-2-[F-18]fluoro-D-glucose positron emission tomography (FDG-PET) in the detection of primary tumors in patients with disseminated carcinoma of unknown primary site. METHODS:Ten studies (involving a total of 221 patients) tat were publish...

journal_title：Cancer

authors： Sève P,Billotey C,Broussolle C,Dumontet C,Mackey JR

更新日期：2007-01-15 00:00:00

abstract：:The records were reviewed for all patients hospitalized at a pediatric oncology center for complications of leukemia (n = 822) or lymphoma (n = 290) during an 8-year period. The results of surveillance cultures (throat, rectal, and urine) and blood cultures were analyzed to identify cases of Candida tropicalis and C. ...

journal_title：Cancer

authors： Marina NM,Flynn PM,Rivera GK,Hughes WT

更新日期：1991-08-01 00:00:00

abstract：:A prospective study of computerized tomography (CT) of the liver using a liver contrast agent compared to conventional CT was undertaken. CT scanning without contrast agents (NC-CT), CT with water-soluble contrast (WSC-CT), and CT with ethiodized oil emulsion (EOE-CT) were performed on patients with possible or probab...

journal_title：Cancer

authors： Sugarbaker PH,Vermess M,Doppman JL,Miller DL,Simon R

更新日期：1984-10-15 00:00:00