Characterization of adolescent and pediatric renal cell carcinoma: A report from the Children's Oncology Group study AREN03B2.

abstract：BACKGROUND:One-carbon metabolism plays a critical role in DNA methylation and DNA synthesis. Variants of genes involved in one-carbon metabolism may result in aberrant methylation and/or DNA synthesis inhibition, and ultimately modulate the initiation and progression of tumors. In this study, the authors hypothesized t...

journal_title：Cancer

authors： Jin G,Huang J,Hu Z,Dai J,Tang R,Chen Y,Xu L,Huang X,Shu Y,Shen H

更新日期：2010-12-15 00:00:00

abstract：BACKGROUND:Prevalence usually is defined as the proportion of individuals alive who previously had a diagnosis of the disease, regardless of whether the individuals still are receiving treatment or are cured. The objective of this study was to estimate the proportion of elderly patients with colorectal carcinoma (CRC) ...

journal_title：Cancer

authors： Mariotto A,Warren JL,Knopf KB,Feuer EJ

更新日期：2003-09-15 00:00:00

abstract：:Flow cytometric measurements were done on 51 ovarian carcinoma specimens collected from consecutive patients in a prospective study. The ploidy status was related to the course of the disease. The tumors from 26 (52%) of 50 evaluable patients had DNA aneuploidy. Patients with diploid tumors were more often considered ...

journal_title：Cancer

authors： Iversen OE

更新日期：1988-03-01 00:00:00

abstract：:The role of hyperthermic isolation perfusion in the treatment of advanced melanoma of the limbs is clearly important. However, attention has in the past been focussed mainly on surgical aspects of the procedure. Whereas, equivalent interest in chemotherapy considerations has been lacking. A group of 15 patients have b...

journal_title：Cancer

authors： Klein ES,Ben-Ari GY

更新日期：1987-03-15 00:00:00

abstract：BACKGROUND:The delivery of effective treatment for pediatric solid tumors poses a particular challenge to centers in middle-income countries (MICs) that already are vigorously addressing pediatric cancer. The objective of this study was to improve the current understanding of barriers to effective treatment of pediatri...

journal_title：Cancer

authors： Friedrich P,Ortiz R,Fuentes S,Gamboa Y,Ah Chu-Sanchez MS,Arambú IC,Montero M,Báez F,Rodríguez-Galindo C,Antillón-Klussmann F,Central American Association of Pediatric Hematologists and Oncologists (AHOPCA).

更新日期：2014-01-01 00:00:00

abstract：:A controlled trial of surgical adjuvant chemotherapy for breast cancer was carried out using 551 Japanese patients. Single or combined treatment with mitomycin C (0.2 mg/kg i.v. three times within five days postoperatively) and cyclophosphamide (100 mg postoperatively daily for four months or longer) was used after ra...

journal_title：Cancer

authors： Koyama H,Wada T,Takahashi Y,Nishizawa Y,Iwanaga T,Aoki Y,Terasawa T,Kosaki G,Kajita A,Wada A

更新日期：1980-12-01 00:00:00

abstract：:Patients with non-Hodgkin's lymphomas who failed to respond to chemotherapy were treated with low dose fractionated total body irradiation (TBI). Prior to during and after scheduled therapy, their clinical status was evaluated and peripheral blood studies were performed to enumerate EAC and E rosetting cells and to me...

journal_title：Cancer

authors： Yonkosky DM,Feldman MI,Cathcart ES,Kim S

更新日期：1978-09-01 00:00:00

abstract：BACKGROUND:The aim of this study was to determine and compare the added prognostic value of screening tools, geriatric assessment (GA) components, and GA summaries to clinical information for overall survival (OS) in older patients with cancer. METHODS:A screening and a 10-item GA were systematically performed in pati...

journal_title：Cancer

authors： Kenis C,Baitar A,Decoster L,De Grève J,Lobelle JP,Flamaing J,Milisen K,Wildiers H

更新日期：2018-09-15 00:00:00

abstract：BACKGROUND:Previous studies in the literature have suggested that radiolabeled F(ab')2 fragments might be superior to whole immunoglobulin G (IgG) for imaging and therapy of cancer because of their greater penetration in tumors. To test this hypothesis, the authors compared tumor and normal tissue uptake along with pla...

journal_title：Cancer

authors： Murray JL,Rosenblum MG,Zhang HZ,Podoloff DA,Kasi LP,Curley SA,Chan JC,Roh M,Hohn DC,Brewer H

更新日期：1994-02-01 00:00:00

abstract：:A 45-year-old man was diagnosed with multiple myeloma, IgA-kappa, in 1975. Thirteen years later he presented with obstructive jaundice. Computed tomography (CT) showed a 6-cm mass in the head of the pancreas. Needle aspiration showed myeloma. The jaundice resolved after treatment with radiotherapy. Extraosseous involv...

journal_title：Cancer

authors： Fischer A,Suhrland MJ,Vogl SE

更新日期：1991-02-01 00:00:00

abstract：:A 12-year-old boy with primary reticulum cell sarcoma of the testis who is alive and free of tumor 32 months after orchiectomy, radiation therapy to inguinal, iliac and retroperitoneal lymph nodes and chemotherapy is reported. Seven previously documented cases of childhood primary testicular lymphoma are reviewed. The...

journal_title：Cancer

authors： Weitzner S,Gropp A

更新日期：1976-02-01 00:00:00

abstract：:From the standpoint of chemotherapy, the first progress in the treatment of Hodgkin's disease was the identification of the activity of nitrogen mustard in the 1940's. The initial antitumor effect of the drug created a great excitement. However, when all patients later relapsed, there was subsequent dejection and skep...

journal_title：Cancer

authors： DeVita VT Jr,Lewis BJ,Rozencweig M,Muggia FM

更新日期：1978-08-01 00:00:00

abstract：BACKGROUND:Data from the Health Care Financing Administration's (HCFA) Medicare Health Outcomes Survey (MHOS) of patients enrolled in managed care services through Medicare were analyzed. The MHOS provided baseline estimates of quality of life of cancer survivors in comparison to a frequency age-matched cohort of nonca...

journal_title：Cancer

authors： Baker F,Haffer SC,Denniston M

更新日期：2003-02-01 00:00:00

abstract：:Activities of glucosephosphate isomerase, lactate dehydrogenase, and NADP-isocitrate dehydrogenase were significantly elevated in breast cancer specimens from patients who responded favorably to combination cytotoxic chemotherapy regimens compared with those in carcinomas from patients failing to respond to the same c...

journal_title：Cancer

authors： Hilf R,Savlov ED,Rector WD,Wittliff JL

更新日期：1976-08-01 00:00:00

abstract：:The authors describe the results of a hospital-based incident case-control study of lung cancer conducted in a high-risk region of southern Louisiana from January 1979 through April 1982. Dietary intake of carotene, retinol, and vitamin C was estimated from food frequency questionnaires administered to 1253 cases and ...

journal_title：Cancer

authors： Fontham ET,Pickle LW,Haenszel W,Correa P,Lin YP,Falk RT

更新日期：1988-11-15 00:00:00

abstract：BACKGROUND:Quality assurance (QA) of clinical practice is important for any medical specialty. Programs based on the Patterns of Care Study (PCS) have been developed to compare the quality of radiotherapeutic care at individual institutions, with the national average representing the process and outcome of radiotherapy...

journal_title：Cancer

authors： Tanisada K,Teshima T,Ohno Y,Inoue T,Abe M,Ikeda H,Owen JB,Hanks GE,Masuda K,Honke Y

更新日期：2002-07-01 00:00:00

abstract：:Medical adrenalectomy, consisting of aminoglutethimide plus either dexamethasone or hydrocortisone, was administered to 53 women with advanced breast cancer. Sixteen (30%) patients had an objective response, five patients had stabilization of disease, 26 patients demonstrated progression of disease, two patients did n...

journal_title：Cancer

authors： Horsley JS 3rd,Newsome HH,Brown PW,Neifeld JP,Terz JJ,Lawrence W Jr

更新日期：1982-03-15 00:00:00

abstract：BACKGROUND:In the current study, the authors focused on determinants influencing the quality of care and variations in the actual quality of integrated care for patients with nonsmall cell lung cancer (NSCLC) to estimate whether there is room for improvement. METHODS:The authors tested the quality of integrated care f...

journal_title：Cancer

authors： Ouwens MM,Hermens RR,Termeer RA,Vonk-Okhuijsen SY,Tjan-Heijnen VC,Verhagen AF,Hulscher MM,Marres HA,Wollersheim HC,Grol RP

更新日期：2007-10-15 00:00:00

abstract：:A patient is described with Gardner's syndrome manifested initially by an extra-abdominal desmoid which was resected. The case was complicated by metastatic adenocarcinoma of the colon and recurrence of several large painful desmoid lesions. In view of the predilection of desmoids to occur in women in their childbeari...

journal_title：Cancer

authors： Kinzbrunner B,Ritter S,Domingo J,Rosenthal CJ

更新日期：1983-12-15 00:00:00

abstract：:In this study the authors applied flow cytometric DNA-ploidy analysis to multiple female genital tract malignant tumors in 43 patients, most of whom (n = 37) had bilateral ovarian cancer. An algorithm was developed for calculation of the likelihood ratio of the probabilities that measured DNA index differences between...

journal_title：Cancer

authors： Smit VT,Fleuren GJ,van Houwelingen JC,Zegveld ST,Kuipers-Dijkshoorn NJ,Cornelisse CJ

更新日期：1990-10-15 00:00:00

abstract：BACKGROUND:Bortezomib is a proteasome inhibitor with manageable clinical toxicity and laboratory evidence of anti-melanoma activity. Therefore, it was considered for clinical testing in patients with metastatic melanoma. METHODS:Patients with metastatic melanoma and adequate hematologic, renal, and hepatic function we...

journal_title：Cancer

authors： Markovic SN,Geyer SM,Dawkins F,Sharfman W,Albertini M,Maples W,Fracasso PM,Fitch T,Lorusso P,Adjei AA,Erlichman C

更新日期：2005-06-15 00:00:00

abstract：BACKGROUND:The current study determined the efficacy and toxicity of weekly paclitaxel in combination with estramustine phosphate (EMP) in patients with androgen-independent prostate carcinoma (AIPC). METHODS:Patients with progressive AIPC received 90 mg/m2 paclitaxel by 1-hour intravenous infusion weekly for 3 weeks,...

journal_title：Cancer

authors： Vaughn DJ,Brown AW Jr,Harker WG,Huh S,Miller L,Rinaldi D,Kabbinavar F

更新日期：2004-02-15 00:00:00

abstract：METHODS:The diagnostic performance of transrectal ultrasound (TRUS) gland volume and prostate specific antigen (PSA) results were evaluated in 204 men consecutively scheduled to undergo transurethral prostatic resection (TUR). RESULTS:Nonpalpable prostate cancer was detected by TRUS alone in 18% (29 of 161) and by TUR...

journal_title：Cancer

authors： Lee F,Littrup PJ,Loft-Christensen L,Kelly BS Jr,McHugh TA,Siders DB,Mitchell AE,Newby JE

更新日期：1992-07-01 00:00:00

abstract：:A case of congenital acute lymphoblastic leukemia (ALL) displayed an X;6 translocation. This is the third reported case of ALL with an X;6 translocation. In addition, two of the three ALL cases occurred during infancy, at ages 2 months and newborn, and both translocations involved the band q15-16 region of chromosome ...

journal_title：Cancer

authors： Carney LA,Kinney JS,Higgins RR,Freeman AI,Hecht BK,Woods GM

更新日期：1992-02-01 00:00:00

abstract：:Laparoscopy is highly effective in diagnosing malignant liver disease, with overall accuracy in the 90% range. Up to 80% of the liver surface can be inspected, and biopsies can be directed with precision. A major advantage over scan guided percutaneous techniques is the ability to detect and biopsy lesions only a few ...

journal_title：Cancer

authors： Lightdale CJ

更新日期：1982-12-01 00:00:00

abstract：BACKGROUND:Uterine serous carcinoma (USC) is not recognized as part of any defined hereditary cancer syndrome, and its association with hereditary breast and ovarian carcinoma and Lynch syndrome are uncertain. METHODS:Using targeted capture and massively parallel genomic sequencing, 151 subjects with USC were assessed...

journal_title：Cancer

authors： Pennington KP,Walsh T,Lee M,Pennil C,Novetsky AP,Agnew KJ,Thornton A,Garcia R,Mutch D,King MC,Goodfellow P,Swisher EM

更新日期：2013-01-15 00:00:00

abstract：BACKGROUND:The authors attempted to obtain shared proteins among lung carcinoma cells by column chromatographies. A glycoprotein with approximately 500 kDa isolated from QG56 cells showed an identical amino acid sequence to 90K/Mac-2 binding protein (M2BP). This protein has been reported to be highly expressed and to m...

journal_title：Cancer

authors： Ozaki Y,Kontani K,Hanaoka J,Chano T,Teramoto K,Tezuka N,Sawai S,Fujino S,Yoshiki T,Okabe H,Ohkubo I

更新日期：2002-11-01 00:00:00

abstract：BACKGROUND:The objective of this study was to determine whether standardized treatment of germ cell tumors (GCTs) could overcome sociodemographic factors limiting patient care. METHODS:The records of all patients undergoing primary treatment for GCTs at both a public safety net hospital and an academic tertiary care c...

journal_title：Cancer

authors： Chertack N,Ghandour RA,Singla N,Freifeld Y,Hutchinson RC,Courtney K,Bowman IA,Arafat W,Meng X,Moore JA,Aydin AM,Sagalowsky AI,Margulis V,Lotan Y,Woldu SL,Bagrodia A

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND:The demonstration of the monoclonality of immunoglobulin heavy chain (IgH) gene rearrangement is an indispensable method for the diagnosis of B-cell lymphoma as well as histocytochemical analysis. For the detection of IgH gene rearrangement, the extraction of DNA from a homogenous cell population is necessar...

journal_title：Cancer

authors： Orba Y,Tanaka S,Nishihara H,Kawamura N,Itoh T,Shimizu M,Sawa H,Nagashima K

更新日期：2003-08-25 00:00:00

abstract：:The authors report the accuracy of mammographically guided fine-needle aspiration (FNA) for the diagnosis of nonpalpable breast lesions in a series of 71 patients. Each mammographically guided FNA was immediately followed by hookwire localization and open biopsy. Seven malignancies were identified cytologically, but t...

journal_title：Cancer

authors： Layfield LJ,Parkinson B,Wong J,Giuliano AE,Bassett LW

更新日期：1991-11-01 00:00:00