Relationship of glycolytic enzyme activities and response of breast cancer patients to chemotherapy: A preliminary report.

abstract：:A case of congenital acute lymphoblastic leukemia (ALL) displayed an X;6 translocation. This is the third reported case of ALL with an X;6 translocation. In addition, two of the three ALL cases occurred during infancy, at ages 2 months and newborn, and both translocations involved the band q15-16 region of chromosome ...

journal_title：Cancer

authors： Carney LA,Kinney JS,Higgins RR,Freeman AI,Hecht BK,Woods GM

更新日期：1992-02-01 00:00:00

abstract：:In 1988, Californians passed Proposition 99, which raised the tobacco tax from 10 cents to 35 cents and allocated 20% of the resulting revenues, approximately $100 million, for tobacco education and 5% for tobacco-related research. Seventy percent was allocated for health care costs and 5% for the environment. In this...

journal_title：Cancer

authors： Martin CB,Beerline D,Breslow L

更新日期：1998-12-15 00:00:00

abstract：BACKGROUND:Through this study, the authors sought to investigate the biologic and immunologic effects of preoperative trastuzumab in patients with ductal carcinoma in situ (DCIS) of the breast. METHODS:Patients with DCIS were enrolled in this open-label phase 2 trial and tested for HER2. Trastuzumab was given by intra...

journal_title：Cancer

authors： Kuerer HM,Buzdar AU,Mittendorf EA,Esteva FJ,Lucci A,Vence LM,Radvanyi L,Meric-Bernstam F,Hunt KK,Symmans WF

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Six human pancreatic carcinoma cell lines, designated as KMP-1 to KMP-6, were established and maintained in vitro for > 3 years. All were derived from pancreatic ductal adenocarcinomas. The six cell lines originated from either primary pancreatic tumors, metastatic liver tumors, or metastases to lymph nodes....

journal_title：Cancer

authors： Kato M,Shimada Y,Tanaka H,Hosotani R,Ohshio G,Ishizaki K,Imamura M

更新日期：1999-02-15 00:00:00

abstract：BACKGROUND:Recent studies revealed that incidence rates of cutaneous melanoma (CM) were leveling off predominantly among younger people and patterns suggested birth-cohort effects. The current study analyzed the development of prognostic factors and survival in incident CM over 25 years. METHODS:All 45,483 patients wi...

journal_title：Cancer

authors： Buettner PG,Leiter U,Eigentler TK,Garbe C

更新日期：2005-02-01 00:00:00

abstract：BACKGROUND:Despite significant advances in understanding the biology of renal cell carcinoma (RCC) during the past decade, metastatic disease remains nearly incurable and a major medical challenge. Because RCC is known to be immunogenic, immunotherapeutic agents such as recombinant human interleukin-2 (rIL-2) and inter...

journal_title：Cancer

authors： Bukowski RM

更新日期：1997-10-01 00:00:00

abstract：:To evaluate the frequency, etiology, and outcome of diffuse interstitial pneumonitis after treatment of children with Stage IV (favorable histologic type) Wilms' tumor using whole-lung and abdominal radiation therapy, and combination chemotherapy, all cases reported in such patients entered on National Wilms' Tumor St...

journal_title：Cancer

authors： Green DM,Finklestein JZ,Tefft ME,Norkool P

更新日期：1989-02-01 00:00:00

abstract：:Nuclear DNA content of paraffin-embedded tissue from 48 adrenocortical neoplasms, 18 histologically normal control adrenal glands, and five hyperplastic adrenal glands was analyzed retrospectively using flow cytometry. Aneuploidy was compared with morphologic criteria as a predictor of recurrence. All 18 controls, fiv...

journal_title：Cancer

authors： Amberson JB,Vaughan ED Jr,Gray GF,Naus GJ

更新日期：1987-06-15 00:00:00

abstract：BACKGROUND:The performance of cytologic screening and its correlation with histology and polymerase chain reaction (PCR) detection of human papillomavirus (HPV) DNA have not been evaluated in populations with a low prevalence of anal intraepithelial neoplasia (AIN). The objective of the current study was to analyze the...

journal_title：Cancer

authors： Etienney I,Vuong S,Si-Mohamed A,Fléjou JF,Atienza P,Bauer P,Cytological Diaconesses Group.

更新日期：2012-12-15 00:00:00

abstract：:While using the natural killer (NK) cell-associated HNK-1 antibody in a panel of hematopoietic cell markers, the authors found that metastatic tumor cells in the bone marrow of a patient with disseminated prostatic carcinoma stained strongly with this antibody using an indirect immunofluorescence technique. More than ...

journal_title：Cancer

authors： Rusthoven JJ,Robinson JB,Kolin A,Pinkerton PH

更新日期：1985-07-15 00:00:00

abstract：BACKGROUND:The authors examined whether survivors from the Childhood Cancer Survivor Study were less likely to be in higher-skill occupations than a sibling comparison and whether certain survivors were at higher risk for lower-skill jobs. METHODS:The authors created 3 mutually exclusive occupational categories for pa...

journal_title：Cancer

authors： Kirchhoff AC,Krull KR,Ness KK,Park ER,Oeffinger KC,Hudson MM,Stovall M,Robison LL,Wickizer T,Leisenring W

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND:Angiogenesis in individuals with various solid tumors has provided useful information on tumor progression and prognosis, and many examples of mast cell (MC) accumulation coupled with angiogenesis can be found in the literature. METHODS:Utilizing monoclonal antibodies for tryptase that are specific markers ...

journal_title：Cancer

authors： Takanami I,Takeuchi K,Naruke M

更新日期：2000-06-15 00:00:00

abstract：:The discovery of genes responsible for inherited forms of colorectal cancer have the potential to improve cancer risk assessment and counseling. Germline mutations (nonsense, frameshift) of APC are associated with familial adenomatous polyposis, an autosomal dominant syndrome, clinically characterized by young onset, ...

journal_title：Cancer

authors： Petersen GM,Brensinger JD,Johnson KA,Giardiello FM

更新日期：1999-12-01 00:00:00

abstract：:Numerous examples exist of prognostic factors that have been conclusively established and that can segregate the target patient population into subgroups with vastly different outcomes. At the same time, we can expect, in the majority of trials being conducted, that if a new treatment turns out to be successful, it ge...

journal_title：Cancer

authors： Sather HN

更新日期：1986-07-15 00:00:00

abstract：BACKGROUND:Inhibition of the hedgehog signaling pathway (HHSP) for the treatment of locally advanced basal cell carcinoma (BCC) and metastatic BCC (mBCC) has produced promising results. Typically, mBCC is not taken into consideration during the workup of a patient with multifocal metastatic disease who has a history of...

journal_title：Cancer

authors： Weiss GJ,Korn RL

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:In multidisciplinary assessment clinics for screen-detected breast lesions, onsite cytopathologists provide immediate results of fine-needle aspiration biopsies (FNABs) and this information is used for patient counseling and treatment planning. Such consultation is not possible for the increasing proportion ...

journal_title：Cancer

authors： Farshid G,Pieterse S

更新日期：2006-06-25 00:00:00

abstract：BACKGROUND:The current study was conducted to evaluate severe mucocutaneous toxicity during treatment with hydroxyurea (HU) in a large cohort of patients with Philadelphia chromosome-negative myeloproliferative neoplasms (MPN). METHODS:Among 993 consecutive patients newly diagnosed with MPN at 4 centers in Rome betwee...

journal_title：Cancer

authors： Latagliata R,Spadea A,Cedrone M,Di Giandomenico J,De Muro M,Villivà N,Breccia M,Anaclerico B,Porrini R,Spirito F,Rago A,Avvisati G,Alimena G,Montanaro M,Andriani A,Gruppo Laziale SMPC Ph1 neg.

更新日期：2012-01-15 00:00:00

abstract：:Twenty-four patients with metastatic cancer of the choroid were seen in the Department of Therapeutic Radiology, Rush-Presbyterian--St. Luke's Medical Center, Chicago, between 1964 and 1975. One fourth of the patients had involvement in both eyes, for a total of 30 eyes involved with metastatic cancer. The most common...

journal_title：Cancer

authors： Reddy S,Saxena VS,Hendrickson F,Deutsch W

更新日期：1981-02-15 00:00:00

abstract：BACKGROUND:The objectives of this study were to evaluate survival among current smokers, former smokers, and never smokers who are diagnosed with non-small cell lung cancer (NSCLC). METHODS:The study included patients who participated in the National Comprehensive Cancer Network's NSCLC Database Project. Current, form...

journal_title：Cancer

authors： Ferketich AK,Niland JC,Mamet R,Zornosa C,D'Amico TA,Ettinger DS,Kalemkerian GP,Pisters KM,Reid ME,Otterson GA

更新日期：2013-02-15 00:00:00

abstract：BACKGROUND:The effect on prognosis of adding imatinib mesylate to the treatment of patients with Philadelphia chromosome (Ph)-positive chronic myelogenous leukemia (CML) has not been explored fully. The objective of the current study was to evaluate the benefit of adding imatinib to the treatment sequence of patients w...

journal_title：Cancer

authors： Kantarjian H,O'Brien S,Cortes J,Shan J,Giles F,Garcia-Manero G,Verstovsek S,Faderl S,Rios MB,Talpaz M

更新日期：2003-10-01 00:00:00

abstract：:The authors describe two cases of epithelioid sarcoma of the vulva and summarize the clinical and pathologic experience with this vulvar neoplasm. Findings indicate that epithelioid sarcoma of the vulva usually occurs in the labia majora of young women, but may occur in later life. Clinically it may mimic a Bartholin'...

journal_title：Cancer

authors： Ulbright TM,Brokaw SA,Stehman FB,Roth LM

更新日期：1983-10-15 00:00:00

abstract：BACKGROUND:The authors suggested that the loss of collagen IV and laminin-containing basement membrane and the loss of Disabled-2 (Dab2) expression were two critical events associated with morphologic dysplastic changes of the ovarian surface epithelium as a step in tumorigenicity. Both the basement membrane and Dab2, ...

journal_title：Cancer

authors： Roland IH,Yang WL,Yang DH,Daly MB,Ozols RF,Hamilton TC,Lynch HT,Godwin AK,Xu XX

更新日期：2003-12-15 00:00:00

abstract：:Methionine-depleting total parenteral nutrition (methionine-depleting TPN), which infuses an amino acid solution devoid of L-methionine and L-cysteine as the sole protein source, showed enhancement of the effect of several anti-cancer agents. In this study, the combined effect of the methionine-depleting TPN with the ...

journal_title：Cancer

authors： Goseki N,Yamazaki S,Endo M,Onodera T,Kosaki G,Hibino Y,Kuwahata T

更新日期：1992-04-01 00:00:00

abstract：BACKGROUND:The current randomized, controlled, multicenter clinical trial was conducted to investigate the efficacy of concurrent neoadjuvant chemotherapy (NCT) and estrogen deprivation in patients with estrogen receptor (ER)-positive, human epidermal growth factor receptor 2 (HER2)-negative breast cancer. METHODS:Eli...

journal_title：Cancer

authors： Yu KD,Wu SY,Liu GY,Wu J,Di GH,Hu Z,Hou YF,Chen CM,Fan L,Tang LC,Shen ZZ,Wu KJ,Zhuang ZG,Zhang HW,Shao ZM

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND:Stereotactic radiation therapy is highly effective in the treatment of small brain metastases, regardless of the histology. This suggests that small extracranial malignancies may be curable with similar radiation therapy. The authors developed a novel treatment unit for administering such therapy. METHODS:T...

journal_title：Cancer

authors： Uematsu M,Shioda A,Tahara K,Fukui T,Yamamoto F,Tsumatori G,Ozeki Y,Aoki T,Watanabe M,Kusano S

更新日期：1998-03-15 00:00:00

abstract：BACKGROUND:Idarubicin (IDR), an anthracycline that is a derivative of daunorubicin, was synthesized in an attempt to find new analogs of daunorubicin with an improved spectrum of activity and diminished acute or chronic toxicity. Because of the favorable pharmacokinetic profile of IDR (with the persistence of its activ...

journal_title：Cancer

authors： Arndt CA,Krailo MD,Steinherz L,Scheithauer B,Liu-Mares W,Reaman GH

更新日期：1998-08-15 00:00:00

abstract：:A distinctive glycopeptide, which acts as an acceptor for a cancer-associated galactosyltransferase, has been detected in sera and effusions of patients with extensive carcinoma. Cancer-associated galactosyltransferase acceptor (CAGA) purified from human malignant effusions was tested for its effects on cell growth in...

journal_title：Cancer

authors： Podolsky DK,Isselbacher KJ

更新日期：1980-03-15 00:00:00

abstract：BACKGROUND:Patients with metastatic melanoma (MM) have very few therapy options. Based on reports of responses to paclitaxel and carboplatin (PC), 31 patients with MM were treated with PC. METHODS:Data regarding patients treated with PC were abstracted from medical records. Clinical outcomes as determined by the treat...

journal_title：Cancer

authors： Rao RD,Holtan SG,Ingle JN,Croghan GA,Kottschade LA,Creagan ET,Kaur JS,Pitot HC,Markovic SN

更新日期：2006-01-15 00:00:00

abstract：:Seven hundred ninety-five patients were adenocarcinomas of the proximal colon were reviewed. Two hundred forty-five patients presented with disseminated disease at the time of diagnosis, and were analyzed to identify mechanisms and sites of disease spread. Five hundred fifty patients underwent radical resection, and w...

journal_title：Cancer

authors： Russell AH,Tong D,Dawson LE,Wisbeck W

更新日期：1984-01-15 00:00:00

abstract：BACKGROUND:The effect of aspirin use on 490 patients with cancer of the colon, 340 with cancer of the rectum as the first primary site, and 212 patients with polyps having no coexisting malignancies was compared with that of two groups of control subjects that consisted of 524 hospital patients having no cancers and no...

journal_title：Cancer

authors： Suh O,Mettlin C,Petrelli NJ

更新日期：1993-08-15 00:00:00