Metastatic basal cell carcinoma in the era of hedgehog signaling pathway inhibitors.

abstract：:In 147 cases of mammary carcinoma, 388 serial mammographies were performed before final treatment. The average retrospective observation time was 27 months with a range of two months to 11 years. The number of serial mammographies per case ranged between two and 11. The tumor volume doubling times (TV); obtained by me...

journal_title：Cancer

authors： von Fournier D,Weber E,Hoeffken W,Bauer M,Kubli F,Barth V

更新日期：1980-04-15 00:00:00

abstract：:Chromosome abnormalities from 17 malignancies that were studied using direct preparations and G-, Q-, and C-banding methods are presented and the findings assessed. The material used was from 6 primary cervical carcinomas, 5 primary and metastatic ovarian carcinomas and 6 other metastatic carcinomas. In general, chrom...

journal_title：Cancer

authors： van der Riet-Fox MF,Retief AE,van Niekerk WA

更新日期：1979-12-01 00:00:00

abstract：:Forty-one previously untreated patients with a diagnosis of acute myelogenous leukemia (AML) were entered on a study using early intensification followed by a short-term maintenance chemotherapy. Induction and early intensification consisted of three to four cycles of doxorubicin, vincristine, cytosine arabinoside (Ar...

journal_title：Cancer

authors： Kantarjian HM,Keating MJ,Walters RS,McCredie KB,Bodey GP,Freireich EJ

更新日期：1986-10-15 00:00:00

abstract：BACKGROUND:New biologic prognostic factors are needed to guide the treatment of patients with colorectal cancer. The prognostic value of the altered expression of the cell surface glycoprotein gp78, which has been implicated in tumor-cell invasion and metastasis as an autocrine motility factor (AMF) receptor, was evalu...

journal_title：Cancer

authors： Nakamori S,Watanabe H,Kameyama M,Imaoka S,Furukawa H,Ishikawa O,Sasaki Y,Kabuto T,Raz A

更新日期：1994-10-01 00:00:00

abstract：BACKGROUND:Postchemotherapy surgery is an essential component in the management of patients with metastatic germ cell tumors (GCT). The authors assessed their institutional experience of retroperitoneal lymph node dissection (RPLND) after multiple chemotherapy regimens for advanced GCT. METHODS:By analyzing the instit...

journal_title：Cancer

authors： Eggener SE,Carver BS,Loeb S,Kondagunta GV,Bosl GJ,Sheinfeld J

更新日期：2007-02-01 00:00:00

abstract：BACKGROUND:Studies of colorectal adenocarcinoma (CRC) indicate a higher mortality rate for African Americans compared with Caucasians in the United States. In the current study, the authors evaluated the racial differences in survival based on tumor location and pathologic stage between African-American patients and Ca...

journal_title：Cancer

authors： Alexander D,Chatla C,Funkhouser E,Meleth S,Grizzle WE,Manne U

更新日期：2004-07-01 00:00:00

abstract：BACKGROUND:The National Pediatric Oncology Unit (UNOP) is the only pediatric hemato-oncology center in Guatemala. METHODS:Patients ages 1 to 17 years with acute lymphoblastic leukemia (ALL) were treated according to modified ALL Intercontinental Berlin-Frankfurt-Münster (IC-BFM) 2002 protocol. Risk classification was ...

journal_title：Cancer

authors： Antillón FG,Blanco JG,Valverde PD,Castellanos M,Garrido CP,Girón V,Letona TR,Osorio EJ,Borrayo DA,Mack RA,Melgar MA,Lorenzana R,Ribeiro RC,Metzger M,Conter V,Rossi E,Valsecchi MG

更新日期：2017-02-01 00:00:00

abstract：BACKGROUND:Patients with superficial (mucosal or submucosal) esophageal carcinoma (SEC) have significantly better survival rates than patients with advanced carcinoma. Some patients with advanced esophageal carcinoma have been reported to test positive for serum p53 antibodies (Abs). Because very few patients with supe...

journal_title：Cancer

authors： Shimada H,Takeda A,Arima M,Okazumi S,Matsubara H,Nabeya Y,Funami Y,Hayashi H,Gunji Y,Suzuki T,Kobayashi S,Ochiai T

更新日期：2000-10-15 00:00:00

abstract：BACKGROUND:In colorectal carcinoma, venous invasion has been related to patient survival. Liver metastasis develops more frequently when venous invasion is present. However, the histologic features and clinical significance of venous invasion are not well understood. METHODS:A histologic study of venous invasion in co...

journal_title：Cancer

authors： Ouchi K,Sugawara T,Ono H,Fujiya T,Kamiyama Y,Kakugawa Y,Mikuni J,Tateno H

更新日期：1996-12-01 00:00:00

abstract：METHODS:Between 1983 and 1989, 42 patients with Stage II, III, and IV, node-negative, squamous cell head and neck cancer were treated with concurrent 5-fluorouracil, cisplatin, and radiation therapy. Two courses of chemotherapy with 30 Gy of concurrent radiation therapy were to be followed in all patients by definitive...

journal_title：Cancer

authors： Adelstein DJ,Sharan VM,Damm C,Earle AS,Shah AC,Haria CD,Trey JE,Carter SG,Hines JD

更新日期：1992-12-01 00:00:00

abstract：:Human cases autopsied at the Department of Pathology, University of Tokyo, were studied to investigate the chronologic changes in the relationship between cigarette smoking and lung cancer occurrence. The results obtained were as follows: (1) it was confirmed that the incidence of lung cancer was significantly higher ...

journal_title：Cancer

authors： Mori W,Sakai R

更新日期：1984-09-15 00:00:00

abstract：BACKGROUND:Intralesional radioimmunotherapy (RAIT) may improve the management of malignant gliomas whose prognosis is, at present, very poor. Current treatment modalities (e.g., surgery, radiotherapy, and chemotherapy) may prolong survival by a few months but cannot prevent tumor recurrence. METHODS:Following one or m...

journal_title：Cancer

authors： Riva P,Arista A,Tison V,Sturiale C,Franceschi G,Spinelli A,Riva N,Casi M,Moscatelli G,Frattarelli M

更新日期：1994-02-01 00:00:00

abstract：BACKGROUND:A hypothesis generated a retrospective analysis of the improvement of survival over time in patients with cutaneous melanoma (CM) in order to identify factors contributing to this progress. METHODS:A cohort of 4791 patients diagnosed with primary CM in southern Germany between 1976 and 2001 was analyzed. Ka...

journal_title：Cancer

authors： Lasithiotakis KG,Leiter U,Eigentler T,Breuninger H,Metzler G,Meier F,Garbe C

更新日期：2007-03-15 00:00:00

abstract：:A study of pneumococcal bacteremia in 56 patients with neoplastic disease from January 1, 1972 to June 30, 1980 is presented and compared to an earlier study between 1955 and 1971. Patients at highest risk were those with Hodgkin's disease who had been splenectomized, multiple myeloma and chronic lymphocytic leukemia ...

journal_title：Cancer

authors： Chou MY,Brown AE,Blevins A,Armstrong D

更新日期：1983-04-15 00:00:00

abstract：BACKGROUND:To the authors' knowledge, little is known to date regarding the prognostic relevance of measuring serum levels of vascular endothelial growth factor (VEGF), a potent stimulator of angiogenesis, in patients with colon carcinoma who undergo surgery. METHODS:Preoperative and postoperative VEGF serum levels we...

journal_title：Cancer

authors： De Vita F,Orditura M,Lieto E,Infusino S,Morgillo F,Martinelli E,Castellano P,Romano C,Ciardiello F,Catalano G,Pignatelli C,Galizia G

更新日期：2004-01-15 00:00:00

abstract：BACKGROUND:A higher total dose of radiation therapy administered in fractionated lower individual doses twice daily (hyperfractionated radiation therapy) has been reported to improve survival for children with brain stem gliomas. However, this higher dose of radiation therapy may cause more sequelae. METHOD:Eighty-eig...

journal_title：Cancer

authors： Packer RJ,Zimmerman RA,Kaplan A,Wara WM,Rorke LB,Selch M,Goldwein J,Allen JA,Boyett J,Albright AL

更新日期：1993-04-15 00:00:00

abstract：BACKGROUND AND METHODS:A univariate and multivariate analysis for the correlation between histomorphologic factors and prognosis was made using data from 1116 patients with soft tissue sarcoma, including 1005 cases available with complete histologic and follow-up data. RESULTS:The overall 5-year survival rate was 43.6...

journal_title：Cancer

authors： Hashimoto H,Daimaru Y,Takeshita S,Tsuneyoshi M,Enjoji M

更新日期：1992-12-15 00:00:00

abstract：:A prospective randomized trial by CALGB examined the relative value of four chemotherapy regimens in 537 patients with stage III B and IV Hodgkin's disease. A new combination BOPP, derived by substitution of BCNU for nitrogen mustard in the MOPP regimen, was compared to MOPP and to two 3-drug regimens, derived by remo...

journal_title：Cancer

authors： Nissen NI,Pajak TF,Glidewell O,Pedersen-Bjergaard J,Stutzman L,Falkson G,Cuttner J,Blom J,Leone L,Sawitsky A,Coleman M,Haurani F,Spurr CL,Harley JB,Seligman B,Cornell C Jr,Henry P,Senn HJ,Brunner K,Martz G,Maurice

更新日期：1979-01-01 00:00:00

abstract：BACKGROUND:Anemia in patients receiving chemotherapy can be ameliorated with recombinant human erythropoietin (rHuEPO), which is administered one to three times per week. Darbepoetin alpha, a new erythropoietic agent, has longer serum residence time, allowing it to be administered less frequently. METHODS:Patients (n ...

journal_title：Cancer

authors： Glaspy JA,Jadeja JS,Justice G,Fleishman A,Rossi G,Colowick AB

更新日期：2003-03-01 00:00:00

abstract：:Immunoblastic sarcoma is a malignancy of transformed lymphocytes with a high association of occurrence in patients with immune disorders. The youngest previously reported case occurred in a 6-year-old child with immunoblastic lymphadenopathy. The authors report the finding of immunoblastic sarcoma of B-cells in a prev...

journal_title：Cancer

authors： Larson T,Katz DA,Mailliard JA

更新日期：1984-11-01 00:00:00

abstract：:Routinely embedded tumors (116 cases) were screened immunohistochemically for the thyroid-associated antigens, thyroglobulin and calcitonin, and for carcinoembryonic antigen (CEA). Also the influence of different fixatives, decalcification, and embedding procedures were studied. All follicular and papillary carcinomas...

journal_title：Cancer

authors： Logmans SC,Jöbsis AC

更新日期：1984-07-15 00:00:00

abstract：BACKGROUND:Radiotherapy (XRT) is effective as the primary treatment modality for laryngopharyngeal cancer; however, complications of XRT can result in significant morbidity. Few previous studies have examined the effect of continued smoking on complications of XRT. The authors of this report hypothesized that patients ...

journal_title：Cancer

authors： Zevallos JP,Mallen MJ,Lam CY,Karam-Hage M,Blalock J,Wetter DW,Garden AS,Sturgis EM,Cinciripini PM

更新日期：2009-10-01 00:00:00

abstract：BACKGROUND:Since endoscopic treatment was first evaluated and established as a treatment for patients with early stage gastric carcinoma, metachronous disease recurrence at other sites in the stomach after endoscopic treatment has become a major problem. METHODS:A retrospective case-control study was conducted on 10 p...

journal_title：Cancer

authors： Kawamura A,Adachi K,Ishihara S,Katsube T,Takashima T,Yuki M,Amano K,Fukuda R,Yamashita Y,Kinoshita Y

更新日期：2001-01-15 00:00:00

abstract：:Both image and flow DNA cytometry were performed in isolated nuclei from paraffin-embedded tumor tissue of patients with small cell carcinoma of the lung (SCCL). In 14 patients tissue was obtained by surgery from the primary tumor. From 14 patients tissue was taken by autopsy. From two patients tissue obtained by both...

journal_title：Cancer

authors： Oud PS,Pahlplatz MM,Beck JL,Wiersma-Van Tilburg A,Wagenaar SJ,Vooijs GP

更新日期：1989-09-15 00:00:00

abstract：:Individualization of treatment using judicious combinations of external and intracavitary irradiation remains the cornerstone of the radiation management of carcinoma of the cervix. The inherent propensity of this cancer to either confine itself to the pelvis or else spread in a systematic and predictable manner throu...

journal_title：Cancer

authors： Rotman M,John M,Boyce J

更新日期：1981-07-15 00:00:00

abstract：BACKGROUND:Cancer of the pancreas is a highly malignant illness with a very poor prognosis. Unfortunately, there has been little in the way of improvement in prognosis over the past 20 years. It is feared by patients because of its reputation as a deadly and often painful disease. Given these realities, it is not surpr...

journal_title：Cancer

authors： Passik SD,Breitbart WS

更新日期：1996-08-01 00:00:00

abstract：:A primary fibrosarcoma of the thyroid occurring in a patient with a nodular goiter is described. Light microscopy showed interwoven bundles of spindle cells admixed with plump ovoid cells, and foci of multinucleated giant cells. Remnants of distorted thyroid follicles were found only at the periphery of the tumor. "Tr...

journal_title：Cancer

authors： Shin WY,Aftalion B,Hotchkiss E,Schenkman R,Berkman J

更新日期：1979-08-01 00:00:00

abstract：BACKGROUND:It is hypothesized that oligometastatic disease represents a state of potentially curable, limited metastases. Stereotactic body radiation therapy (SBRT) is an option for patients who are not amenable to or do not want resection. METHODS:From 2001 to 2006, 121 patients with < or =5 detectable metastases wer...

journal_title：Cancer

authors： Milano MT,Katz AW,Muhs AG,Philip A,Buchholz DJ,Schell MC,Okunieff P

更新日期：2008-02-01 00:00:00

abstract：BACKGROUND:Although the biologic characteristics of papillary cystic tumors (PCT) generally indicate a good prognosis, a malignant form has been reported. METHODS:Twenty-two examples of PCT were examined to assess their malignant potential by histologic, flow cytometric, and immunohistochemical studies. RESULTS:Three...

journal_title：Cancer

authors： Nishihara K,Nagoshi M,Tsuneyoshi M,Yamaguchi K,Hayashi I

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND:High-dose methotrexate (MTX) is an important component of current protocols for the treatment of osteosarcoma. Although MTX uptake proceeds primarily through the reduced folate carrier (RFC) protein and efflux occurs via multidrug resistance protein 1 (MRP1), RFC protein expression in osteosarcoma remains un...

journal_title：Cancer

authors： Ifergan I,Meller I,Issakov J,Assaraf YG

更新日期：2003-11-01 00:00:00