Expression of autocrine motility factor receptor in colorectal cancer as a predictor for disease recurrence.

abstract：:Breast cancer tissue from 12 male patients was evaluated for the presence of estrogen receptors (ER), and at least 10 of 12 were found to be high in ER (ER+). A combination of previously published cases and our own experience indicates that 80% of patients (37/47) have ER+ tumors. This incidence of ER positivity in me...

journal_title：Cancer

authors： Friedman MA,Hoffman PG Jr,Dandolos EM,Lagios MD,Johnston WH,Siiteri PK

更新日期：1981-01-01 00:00:00

abstract：:A prospective study was performed on 84 patients with neuroendocrine pancreatic tumors. Fifty-nine (70%) had malignant tumors and received causal medical treatment. Streptozotocin in combination with 5-fluorouracil or doxorubicin was used as first-line treatment and produced overall objective responses in 20 of 44 (45...

journal_title：Cancer

authors： Eriksson B,Skogseid B,Lundqvist G,Wide L,Wilander E,Oberg K

更新日期：1990-05-01 00:00:00

abstract：BACKGROUND:It has previously been shown that heparanase-1 (HPR1), an endoglycosidase, is up-regulated in pancreatic carcinoma. The purpose of this study was to test whether serum HPR1 levels in pancreatic carcinoma patients are elevated, and whether higher serum HPR1 levels are associated with a shortened survival. ME...

journal_title：Cancer

authors： Quiros RM,Rao G,Plate J,Harris JE,Brunn GJ,Platt JL,Gattuso P,Prinz RA,Xu X

更新日期：2006-02-01 00:00:00

abstract：BACKGROUND:A large amount of interindividual variability exists in the occurrence of symptoms in patients receiving chemotherapy (CTX). The purposes of the current study, which was performed in a sample of 582 oncology outpatients who were receiving CTX, were to identify subgroups of patients based on their distinct ex...

journal_title：Cancer

authors： Miaskowski C,Cooper BA,Melisko M,Chen LM,Mastick J,West C,Paul SM,Dunn LB,Schmidt BL,Hammer M,Cartwright F,Wright F,Langford DJ,Lee K,Aouizerat BE

更新日期：2014-08-01 00:00:00

abstract：BACKGROUND:Hepatic artery administration of iodine-131-Lipiodol serves as a modality that delivers targeted radiation therapy to hepatocellular carcinoma. Its efficacy has been promising according to trials conducted in the adjuvant setting after hepatic resection. Further investigation of its role in the palliative se...

journal_title：Cancer

authors： Chua TC,Chu F,Butler SP,Quinn RJ,Glenn D,Liauw W,Morris DL

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND:Fulvestrant (ICI 182,780) is a new type of estrogen receptor (ER) antagonist that down-regulates the ER and has no known agonist effects. The authors report the prospectively planned combined analysis of data from 2 Phase III trials comparing fulvestrant 250 mg monthly (n=428) and anastrozole 1 mg daily (n=4...

journal_title：Cancer

authors： Robertson JF,Osborne CK,Howell A,Jones SE,Mauriac L,Ellis M,Kleeberg UR,Come SE,Vergote I,Gertler S,Buzdar A,Webster A,Morris C

更新日期：2003-07-15 00:00:00

abstract：BACKGROUND:Patients with advanced cancer often experience fatigue and other symptoms that negatively impact their quality of life. The current trial investigated the effect of melatonin on fatigue and other symptoms in patients with advanced cancer. METHODS:Patients who were aged ≥18 years, had a histologically confir...

journal_title：Cancer

authors： Lund Rasmussen C,Klee Olsen M,Thit Johnsen A,Petersen MA,Lindholm H,Andersen L,Villadsen B,Groenvold M,Pedersen L

更新日期：2015-10-15 00:00:00

abstract：BACKGROUND:The purpose of this study was to present planning, feasibility, toxicity, and outcome of helical tomotherapy for spinal cord-sparing reirradiation of spinal metastases and tumors. METHODS:Thirty-six patients with spinal metastases and tumors who had undergone previous radiotherapy were reirradiated with hel...

journal_title：Cancer

authors： Sterzing F,Hauswald H,Uhl M,Herm H,Wiener A,Herfarth K,Debus J,Krempien R

更新日期：2010-08-15 00:00:00

abstract：:Almost all patients with prostatic cancer will eventually escape the control of the first-line endocrine therapy and relapse. This escape is attributed to selecting and/or cloning preexisting or de novo appearing hormone-independent or resistant cell lines and occurs in most patients after a median time of 12 to 18 mo...

journal_title：Cancer

authors： Mahler C,Denis L

更新日期：1992-07-01 00:00:00

abstract：:A case of meningeal melanocytoma of the left Meckel's cave associated with ipsilateral Ota's nevus in a 43-year-old woman, was studied by light and electron microscopy. The cells of the tumor were characterized by the presence of dendritic cytoplasmic processes, melanosomes and premelanosomes; hence, they were deemed ...

journal_title：Cancer

authors： Botticelli AR,Villani M,Angiari P,Peserico L

更新日期：1983-06-15 00:00:00

abstract：:Fifty-nine colorectal carcinomas of patients with verified cancer family syndrome (CFS) were analyzed for DNA ploidy using flow cytometry. Sixty-eight percent of the tumors were diploid, and 32% were aneuploid. The aneuploid tumors had a median DNA index of 1.24 (range, 1.12-1.97). In 90% of all tumors the DNA index w...

journal_title：Cancer

authors： Kouri M,Laasonen A,Mecklin JP,Järvinen H,Franssila K,Pyrhönen S

更新日期：1990-04-15 00:00:00

abstract：:A 26-year-old man with erythroleukemia was found to have circulating micromegakaryocytes . Megakaryocytic features were defined by morphologic and cytochemical studies using light and electron microscopy with platelet-megakaryocyte peroxidase staining. This appears to be the first reported instance of erythroleukemia ...

journal_title：Cancer

authors： Yamauchi K,Miyauchi J,Nagao T

更新日期：1984-06-15 00:00:00

abstract：BACKGROUND:It is believed that atypical cells identified by nipple duct lavage (NDL) indicate an increased risk for breast carcinoma similar to atypical ductal hyperplasia diagnosed by tissue biopsy, but many basic performance characteristics of NDL currently are undefined. METHODS:NDL was performed in 108 patients un...

journal_title：Cancer

authors： Johnson-Maddux A,Ashfaq R,Cler L,Naftalis E,Leitch AM,Hoover S,Euhus DM

更新日期：2005-03-15 00:00:00

abstract：:The value of a 3-day Hemoccult II test in the diagnosis of colorectal disease in patients receiving anticoagulant therapy was studied. The influence of rehydration and nonrehydration of the slide was investigated, as well as the reproducibility of positive tests. Eight hundred forty-nine patients on anticoagulant ther...

journal_title：Cancer

authors： Kewenter J,Svanvik J,Svensson C,Wållgren K

更新日期：1984-12-15 00:00:00

abstract：BACKGROUND:Acquired Glanzmann's thrombasthenia is a rare hemorrhagic diathesis resulting from impaired adhesive function of the platelet receptor GPIIb/IIIa (alpha(IIb)beta3). Typically, this disorder develops during adulthood, with patients manifesting fluctuating clinical and laboratory findings. To date, the underly...

journal_title：Cancer

authors： Malik U,Dutcher JP,Oleksowicz L

更新日期：1998-05-01 00:00:00

abstract：:With increasing evidence that cancer patients respond immunologically to their cancers, it seemed interesting to investigate whether or not the course of the second cancer differed from that of the first. If we assume that, in analogy to mammary cancer in the mouse, the cells of human breast cancers carry shared antig...

journal_title：Cancer

authors： Khafagy MM,Schottenfeld D,Robbins GF

更新日期：1975-03-01 00:00:00

abstract：BACKGROUND:Population-based studies suggest that, because of inequalities in treatment, black women with localized endometrial cancer have shorter survival compared with white women. The objective of the current investigation was to determine whether there is a racial disparity in outcome between black patients and whi...

journal_title：Cancer

authors： Maxwell GL,Tian C,Risinger JI,Hamilton CA,Barakat RR,Gynecologic Oncology Group Study.

更新日期：2008-09-15 00:00:00

abstract：BACKGROUND:Microsatellite instability (MIN) appears to be a novel molecular mechanism in carcinogenesis and is believed to reflect multiple replication errors. The authors analyzed MIN in de novo acute leukemia and its association with expression of the human MSH3 (hMSH3) gene and point mutations of the N-ras gene. The...

journal_title：Cancer

authors： Tanosaki S,Inokuchi K,Shimada T,Dan K

更新日期：1998-08-01 00:00:00

abstract：:Chondrosarcoma of the foot is a very unusual entity. A case arising from a solitary osteocartilagenous exostosis is presented and the literature is reviewed and discussed. ...

journal_title：Cancer

authors： Lewis MM,Marcove RC,Bullough PG

更新日期：1975-08-01 00:00:00

abstract：:Malignant fibrous histiocytoma (MFH) was produced by injection of 9,10-dimethyl-1,2-benzanthracene (DMBA) into the rat knee joint. The tumor was observed in or around the knee in nearly all the animals 13 to 36 weeks after the initial DMBA administration. Histologically, these lesions were of the storiform-pleomorphic...

journal_title：Cancer

authors： Sakamoto K

更新日期：1986-06-15 00:00:00

abstract：BACKGROUND:The authors evaluated the efficacy of adjuvant chemotherapy with 5-fluorouracil (5-FU) plus doxorubicin in gastric carcinoma after D2-3 curative resection. They also evaluated the effect of dose-related factors (delivered total dose/m(2), actual dose intensity [ADI], relative dose intensity [RDI]) of this re...

journal_title：Cancer

authors： Jeung HC,Rha SY,Noh SH,Min JS,Kim BS,Chung HC

更新日期：2001-06-01 00:00:00

abstract：:A search of the records of 10 pediatric oncology centers revealed 102 children with more than one malignant neoplasm. In this group of 102 patients, all pediatric cancers were seen as initial lesions, but Wilms' tumor and retinoblastoma were over-represented and leukemia and brain tumors underrepresented. Survival var...

journal_title：Cancer

authors： Meadows AT,D'Angio GJ,Miké V,Banfi A,Harris C,Jenkin RD,Schwartz A

更新日期：1977-10-01 00:00:00

abstract：:The poor postsurgical prognosis in patients with colorectal cancer of the Dukes' C classification has prompted a clinical trial of adjuvant immunotherapy versus chemoimmunotherapy intended to prolong either the disease-free interval or the overall survival or both. One hundred and twenty-one patients have been entered...

journal_title：Cancer

authors： Mavligit GM,Gutterman JU,Malahy MA,Burgess MA,McBride CM,Jubert A,Hersh EM

更新日期：1977-11-01 00:00:00

abstract：:The reactivity of serum alpha-fetoprotein (AFP) from 20 patients with hepatocellular carcinoma (HCC) with immobilized lentil lectin was examined and found to be significantly greater (39% +/- 18%) than that of the same protein from seven patients with chronic liver disease (CLD, 11.2% +/- 3.3%), seven with fulminant h...

journal_title：Cancer

authors： Du MQ,Hutchinson WL,Johnson PJ,Williams R

更新日期：1991-01-15 00:00:00

abstract：:Kaposi's sarcoma developed in two lymphoma patients previously treated by chemotherapy and chemoirradiation. The histologic picture in the two cases showed a non-Hodgkin's lymphoma with multifocal epithelioid histiocytic reaction. Both patients had Hepatitis-B surface antigen and other infections due to herpes and str...

journal_title：Cancer

authors： Berrebi A,Shtalrid M,Hurwitz N,Frumkin A,Schattner A

更新日期：1984-08-15 00:00:00

abstract：BACKGROUND:Historically, estrogen receptor (ER) determinations have been made by the ligand-binding assay of tumor homogenates, primarily by the dextran-coated charcoal method (DCC). Immunocytochemical assays (ICA) for ER are more recent and have been executed mostly on frozen sections with the monoclonal antibody H222...

journal_title：Cancer

authors： Pertschuk LP,Feldman JG,Kim YD,Braithwaite L,Schneider F,Braverman AS,Axiotis C

更新日期：1996-06-15 00:00:00

abstract：:Chemotherapy once relegated to end stage patients has markedly improved with the use of combinations. Response rates with single agents have improved from 15 to 35%, to 50 to 70%, using combinations with an increase in complete response rates to about 25%. A series of four studies completed by the Eastern Cooperative ...

journal_title：Cancer

authors： Carbone PP,Bauer M,Band P,Tormey D

更新日期：1977-06-01 00:00:00

abstract：BACKGROUND:The current study examines 1) the sensitivity of detection and 2) sampling and screening/diagnostic error in the cytologic diagnosis of adenocarcinoma in situ (AIS) of the cervix. The data were taken from public and private sector screening laboratories reporting 25,000 and 80,000 smears, respectively, each ...

journal_title：Cancer

authors： Schoolland M,Segal A,Allpress S,Miranda A,Frost FA,Sterrett GF

更新日期：2002-12-25 00:00:00

abstract：:After a series of studies on the linkage of reserpine with breast cancer, both evidence and interpretation appeared to be in conflict. Our case-control survey of long-term, comprehensive records from the Kaiser Foundation Medical Care Program, on 108 hypertensive breast cancer cases and 324 hypertensive controls, matc...

journal_title：Cancer

authors： Kodlin D,McCarthy N

更新日期：1978-02-01 00:00:00

abstract：:The unique characteristics of tumor vasculature represent an attractive target that may be exploited by vascular-targeting anticancer agents. A promising strategy involves the selective disruption of established tumor blood vessels by tumor-vascular disrupting agents (tumor-VDAs), which exhibit antivascular activity, ...

journal_title：Cancer

authors： McKeage MJ,Baguley BC

更新日期：2010-04-15 00:00:00