Early intensification and short-term maintenance chemotherapy does not prolong survival in acute myelogenous leukemia.

abstract：:The objective of this study was to evaluate the sensitivity of two methods for determining bone marrow involvement with non-Hodgkin's lymphoma. These methods were histologic review of bone marrow aspirates, and clot sections versus in vitro growth of lymphoma colonies on soft agar. Forty-two bone marrow aspirates were...

journal_title：Cancer

authors： Smith SD,Kisker S,Bush L,Trueworthy RC

更新日期：1984-04-15 00:00:00

abstract：BACKGROUND:Many histologic classifications of thymic epithelial tumors have been reported to date, but to the authors' knowledge, none of them closely reflect the clinical behavior or prognosis of the tumor. Therefore, it is necessary to establish a biologic marker for thymic epithelial tumors. Variants of CD44 may be ...

journal_title：Cancer

authors： Sonobe S,Miyamoto H,Nobukawa B,Izumi H,Futagawa T,Ishikawa N,Yamazaki A,Uekusa T,Abe H,Suda K

更新日期：2005-05-15 00:00:00

abstract：:Thirty-one patients with advanced, biopsy-proven squamous cell carcinoma (SCC) of the head and neck were treated with intraarterial chemotherapy (IAC) and subsequent radical surgery. Cisplatin at 25 mg/d (4 hours of infusion) and bleomycin at 15 mg/d (20 hours of infusion) were administered for 10 consecutive days. Ra...

journal_title：Cancer

authors： Sulfaro S,Frustaci S,Volpe R,Barzan L,Comoretto R,Monfardini S,Carbone A

更新日期：1989-09-01 00:00:00

abstract：BACKGROUND:This study was conducted to evaluate whether estramustine (estrogen mustard [EM]) is a promising alternative in the treatment of patients with epithelial ovarian carcinoma (OVCA). EM is a microtubule-associated protein (MAP) specific antimicrotubule agent with low toxicity. METHODS:The authors investigated ...

journal_title：Cancer

authors： Chen Z,Fadiel A,Jia JF,Sakamoto H,Carbone R,Naftolin F

更新日期：1999-06-15 00:00:00

abstract：:Unraveling cancer-associated molecular defects is crucial for further pharmacological targeting. Although novel techniques are being developed to elucidate genomic, proteomic, and transcriptomic alterations, the map of protein interactions and aberrations in normal but also in malignant cells is still obscure. It has ...

journal_title：Cancer

authors： Karamouzis MV,Papavassiliou AG

更新日期：2014-02-01 00:00:00

abstract：:This report is to make the general scientific community aware of availability of human tissues through this network. During the short period of its existence, this network has developed useful procedures for distributing human tumor tissue in a rapid, scientifically useful, cost-effective manner to investigators to wh...

journal_title：Cancer

authors： Clausen KP,Grizzle WE,Livolsi V,Newton WA Jr,Aamodt R

更新日期：1989-04-01 00:00:00

abstract：:In January, 1972, the Southwest Oncology Group initiated two randomized studies for patients with advanced breast cancer. The study for patients with prior chemotherapy showed a 33% response rate with adriamycin. The study for patients without previous chemotherapy consisted of three treatment regimens; a weekly repea...

journal_title：Cancer

authors： Hoogstraten B,George SL,Samal B,Rivkin SE,Costanzi JJ,Bonnet JD,Thigpen T,Braine H

更新日期：1976-07-01 00:00:00

abstract：BACKGROUND:Previous studies have shown that low levels of p27(Kip1), an inhibitor of G1 cyclin-dependent kinases, are associated with high aggressiveness and poor prognosis in a variety of cancers. Decreased levels of p27 are caused, at least in part, by acceleration of the rate of its ubiquitin-mediated degradation. I...

journal_title：Cancer

authors： Hershko D,Bornstein G,Ben-Izhak O,Carrano A,Pagano M,Krausz MM,Hershko A

更新日期：2001-05-01 00:00:00

abstract：BACKGROUND:Cancer and its treatment lead to increased financial distress for patients. To the authors' knowledge, to date, no standardized patient-reported outcome measure has been validated to assess this distress. METHODS:Patients with AJCC Stage IV solid tumors receiving chemotherapy for at least 2 months were recr...

journal_title：Cancer

authors： de Souza JA,Yap BJ,Wroblewski K,Blinder V,Araújo FS,Hlubocky FJ,Nicholas LH,O'Connor JM,Brockstein B,Ratain MJ,Daugherty CK,Cella D

更新日期：2017-02-01 00:00:00

abstract：:Hereditary adenomatosis of the colon and rectum (HACR) is associated with a wide variety of extracolonic manifestations. Two cases of neoplasia involving the adrenal gland are reported, one adenoma and one carcinoma. The literature relating these lesions to HACR and other syndromes of malignant and nonmalignant growth...

journal_title：Cancer

authors： Painter TA,Jagelman DG

更新日期：1985-05-01 00:00:00

abstract：BACKGROUND:The incidence of rectal cancer in the United States in young patients is considered to be low. Underestimating this incidence may result in a failure to diagnose younger patients with rectal cancer in a timely manner. METHODS:The authors conducted a retrospective cohort study using Surveillance, Epidemiolog...

journal_title：Cancer

authors： Meyer JE,Narang T,Schnoll-Sussman FH,Pochapin MB,Christos PJ,Sherr DL

更新日期：2010-09-15 00:00:00

abstract：BACKGROUND:Cytologic distinction between follicle center lymphoma (FCL) and mantle cell lymphoma (MCL) is difficult with cytomorphology alone and requires immunophenotyping. The current study describes the distinction between follicle center and mantle cell lymphoma made with fine-needle aspiration (FNA) material. MET...

journal_title：Cancer

authors： Rassidakis GZ,Tani E,Svedmyr E,Porwit A,Skoog L

更新日期：1999-08-25 00:00:00

abstract：:A 29-year-old man with metastatic extraadrenal pheochromocytoma developed paraplegia which reversed completely after megavoltage irradiation of the dorsolumbar spine. Later, treated with cyclophosphamide, vincristine, and dacarbazine, he had a temporary decrease in plasma norepinephrine concentration, a partial recalc...

journal_title：Cancer

authors： Siddiqui MZ,Von Eyben FE,Spanos G

更新日期：1988-08-15 00:00:00

abstract：BACKGROUND:The lack of comparable metrics to evaluate prevention and early detection patient navigation programs impeded the ability to identify best practices. METHODS:The Prevention and Early Detection Workgroup of the Patient Navigation Leadership Summit was charged with making recommendations for common clinical m...

journal_title：Cancer

authors： Battaglia TA,Burhansstipanov L,Murrell SS,Dwyer AJ,Caron SE,Prevention and Early Detection Workgroup, National Patient Navigation Leadership Summit.

更新日期：2011-08-01 00:00:00

abstract：BACKGROUND:The response to antifungal therapy alone often is suboptimal in patients with cancer who have therapy-refractory neutropenia, and even donor-derived granulocyte transfusions (GTX) are not always successful. The authors evaluated the safety and efficacy of immune enhancement using recombinant interferon gamma...

journal_title：Cancer

authors： Safdar A,Rodriguez GH,Lichtiger B,Dickey BF,Kontoyiannis DP,Freireich EJ,Shpall EJ,Raad II,Kantarjian HM,Champlin RE

更新日期：2006-06-15 00:00:00

abstract：BACKGROUND:The Women's Health Initiative randomized clinical trial reported that menopausal hormone therapy increases lung cancer mortality risk. If this is true, use of anti-estrogens should be associated with decreased lung cancer mortality risk. The authors compared lung cancer incidence and mortality among breast c...

journal_title：Cancer

authors： Bouchardy C,Benhamou S,Schaffar R,Verkooijen HM,Fioretta G,Schubert H,Vinh-Hung V,Soria JC,Vlastos G,Rapiti E

更新日期：2011-03-15 00:00:00

abstract：BACKGROUND:Inactivation of the tumor suppressor gene PTEN/MMAC1/TEP1, located on chromosome 10q23, is a common event in advanced stages of diverse human malignancies. However, the prognostic role of PTEN expression in patients with hepatocellular carcinoma (HCC) has not been characterized. METHODS:One hundred five res...

journal_title：Cancer

authors： Hu TH,Huang CC,Lin PR,Chang HW,Ger LP,Lin YW,Changchien CS,Lee CM,Tai MH

更新日期：2003-04-15 00:00:00

abstract：:This article documents the study of 383 cases of lung cancer in uranium miners and presents for the first time the relationship of radioactive radon gas and cigarette smoking. There is evidence that alpha radiation from radon gas at exposure levels above 465 working level months (WLM) is a strong contributor to the de...

journal_title：Cancer

authors： Saccomanno G,Huth GC,Auerbach O,Kuschner M

更新日期：1988-10-01 00:00:00

abstract：BACKGROUND:The results and consequences of genetic testing in a family with familial medullary thyroid carcinoma (FMTC) are described. METHODS:In the screening of relatives, serum calcitonin is replaced by RET mutation analysis that was performed in families suspected of hereditary medullary thyroid carcinoma (MTC). I...

journal_title：Cancer

authors： Hansen HS,Torring H,Godballe C,Jäger AC,Nielsen FC

更新日期：2000-08-15 00:00:00

abstract：:This prospective evaluation of 5-fluorouracil (5-FU) and methyl-CCNU administered in combination to patients with surgery for histologically proved gastric adenocarcinoma is based upon 312 patients randomized between August 1974 and May 1980. Patients were stratified into three categories of resectability, (1) complet...

journal_title：Cancer

authors： Higgins GA,Amadeo JH,Smith DE,Humphrey EW,Keehn RJ

更新日期：1983-09-15 00:00:00

abstract：:The dose of adjuvant chemotherapy for breast cancer may be an important factor in the success of the treatment program. In a retrospective analysis, the authors determined whether patients who were irradiated either postoperatively (N = 29) or as part of primary treatment (N = 13) received a lower dose of adjuvant cyc...

journal_title：Cancer

authors： Levine JF,Coleman CN,Cox RS,Ray GR,Rogoway WM,Martinez A,Stockdale FE

更新日期：1984-01-15 00:00:00

abstract：BACKGROUND:Systemic anticancer therapies can produce acute and chronic organ damage, but the eye is usually considered a protected site. Nonetheless, the oculo-visual system has a potentially high degree of sensitivity to toxic substances. Ocular toxicity induced by cancer chemotherapy includes a broad spectrum of diso...

journal_title：Cancer

authors： al-Tweigeri T,Nabholtz JM,Mackey JR

更新日期：1996-10-01 00:00:00

abstract：BACKGROUND:Atypical and anaplastic meningiomas tend to recur and to invade adjacent brain, bone, and skin. They also can metastasize to extracranial organs such as the lung, liver, or bone, causing death. Recent reports have indicated that allelic deletion of chromosome 1p is associated with malignant progression of me...

journal_title：Cancer

authors： Ishino S,Hashimoto N,Fushiki S,Date K,Mori T,Fujimoto M,Nakagawa Y,Ueda S,Abe T,Inazawa J

更新日期：1998-07-15 00:00:00

abstract：BACKGROUND:Epidermal growth factor (EGF) and EGF-regulated processes play an important role in steroid signal transduction. Comparative analysis of EGF and steroid receptor expression and the sensitivity of early stages of proliferation induction, such as activation of phospholipid turnover to EGF and steroids, may pro...

journal_title：Cancer

authors： Gershtein ES,Shatskaya VA,Kostyleva OI,Ermilova VD,Kushlinsky NE,Krasil'nikov MA

更新日期：1995-12-15 00:00:00

abstract：:Paraneoplastic nervous system syndromes are being identified with increasing frequency because of greater physician awareness and the availability of serodiagnostic tests for some syndromes. Frequently, paraneoplastic syndromes develop in the setting of an indolent, limited stage, or otherwise occult malignancy. As a ...

journal_title：Cancer

authors： Glantz MJ,Biran H,Myers ME,Gockerman JP,Friedberg MH

更新日期：1994-01-01 00:00:00

abstract：BACKGROUND:Sunitinib malate is an orally bioavailable tyrosine kinase inhibitor that is active against many tyrosine kinase receptors involving crucial pathways in both healthy tissues and malignant tissues. Because its use in clinical practice is quite recent, many of its possible side effects remain unknown. In this ...

journal_title：Cancer

authors： Baldazzi V,Tassi R,Lapini A,Lunghi A,Garofoli E,Caruso S,Carini M,Mazzanti R

更新日期：2012-06-15 00:00:00

abstract：:This presentation will focus on the issues of access to care, insurance, and personpower in pediatric oncology. The invitation to participate in this workshop was addressed to me as former Chairman of the Section of Hematology/Oncology of the American Academy of Pediatrics and current Chairman of the sub-board of Pedi...

journal_title：Cancer

authors： Gilchrist GS

更新日期：1993-05-15 00:00:00

abstract：:Flow cytometric analysis of nuclear DNA content was performed on excised malignant tissue of the esophagus. The DNA ploidy pattern was compared with a variety of histologic parameters and the subsequent clinical course to determine whether or not this pattern is associated with the mode of malignant potentiality. Of t...

journal_title：Cancer

authors： Kaketani K,Saito T,Kobayashi M

更新日期：1989-08-15 00:00:00

abstract：:Six breast cancer patients were treated recently for renal insufficiency secondary to neoplasic involvement of the ureters. This complication usually occurs in long standing hormonal-dependent breast cancer with bone metastases. Diagnosis was performed by abdominal echography. Ureteral catheterization or percutaneous ...

journal_title：Cancer

authors： Recloux P,Weiser M,Piccart M,Sculier JP

更新日期：1988-05-01 00:00:00

abstract：BACKGROUND:Colorectal cancer (CRC) is the third most common cause of cancer deaths; however, rates of regular screening for this cancer are low. A quality improvement (QI) program to increase CRC screening was developed for use in a managed care health plan. METHODS:Thirty-six provider organizations (POs) contracting ...

journal_title：Cancer

authors： Ganz PA,Farmer MM,Belman MJ,Garcia CA,Streja L,Dietrich AJ,Winchell C,Bastani R,Kahn KL

更新日期：2005-11-15 00:00:00