Abstract:
:Hereditary adenomatosis of the colon and rectum (HACR) is associated with a wide variety of extracolonic manifestations. Two cases of neoplasia involving the adrenal gland are reported, one adenoma and one carcinoma. The literature relating these lesions to HACR and other syndromes of malignant and nonmalignant growth disturbance is reviewed. The increasing list of the extracolonic manifestations associated with HACR emphasizes the generalized nature of the growth disorder of this disease. An increased awareness of these lesions is important, as many patients with HACR now live longer by avoiding death from colorectal carcinomas due to the increasing usage of prophylactic colectomy.
journal_name
Cancerjournal_title
Cancerauthors
Painter TA,Jagelman DGdoi
10.1002/1097-0142(19850501)55:9<2001::aid-cncr2820subject
Has Abstractpub_date
1985-05-01 00:00:00pages
2001-4issue
9eissn
0008-543Xissn
1097-0142journal_volume
55pub_type
杂志文章相关文献
CANCER文献大全abstract::Two hundred ninety-three patients with Stage IB carcinoma of the uterine cervix were treated by intracavitary irradiation followed by radical hysterectomy and pelvic lymph node dissection in the 3-year period 1970 to 1972, inclusive. Preoperative lymphography was performed and intraoperative films were taken to obtain...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19841115)54:10<2215::aid-cncr282
更新日期:1984-11-15 00:00:00
abstract:BACKGROUND:The authors are interested in identifying molecular markers that can aid in the diagnosis of adrenocortical carcinoma (ACC). The aim of this study was to identify microRNAs (miRNAs or miRs) that are differentially expressed in malignant adrenocortical tumors as compared with benign tumors and assess their po...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.25724
更新日期:2011-04-15 00:00:00
abstract:BACKGROUND:Recently, a 23-gene signature was developed to produce a melanoma diagnostic score capable of differentiating malignant and benign melanocytic lesions. The primary objective of this study was to independently assess the ability of the gene signature to differentiate melanoma from benign nevi in clinically re...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.30385
更新日期:2017-02-15 00:00:00
abstract:BACKGROUND:In vitro studies have shown an antiproliferative effect of tumor necrosis factor (TNF) against various nonsmall cell lung carcinoma (NSCLC) cell lines. However, clinical trials of combined interleukin-2 and TNF-alpha in patients with advanced NSCLC have demonstrated both conflicting and disappointing results...
journal_title:Cancer
pub_type: 杂志文章
doi:
更新日期:1998-07-15 00:00:00
abstract::The authors found metastases to the heart in 10.7% of 1029 autopsy cases in which a malignant neoplasm was diagnosed. The lung was the commonest primary site (36.4%) and adenocarcinoma was the most frequent cell type (36.4%) of neoplasms metastatic to heart. Nonepithelial tumors accounted for 22.7% of cardiac metastas...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19900315)65:6<1456::aid-cncr2820
更新日期:1990-03-15 00:00:00
abstract::Forty-milligram strips of malignant breast tissue were divided longitudinally into 20-mg microsamples. Soluble protein concentration was determined for one-half, and histologic evaluation for viable carcinoma content was made on its sister half. The correlation coefficient for 88 such comparisons was 0.330. This sugge...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19820601)49:11<2383::aid-cncr282
更新日期:1982-06-01 00:00:00
abstract::From 1977, 29 patients with inoperable non-small cell lung carcinoma due to locally far-advanced disease underwent lung resection after receiving two to eight courses of chemotherapy. After the surgery was performed, three additional courses of chemotherapy were given. The overall median survival from onset of the che...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19860201)57:3<630::aid-cncr28205
更新日期:1986-02-01 00:00:00
abstract:BACKGROUND:A positive influence of anticoagulant treatment in small cell lung cancer (SCLC) has been suggested by experimental and clinical data. METHODS:In a multicenter clinical trial, 277 patients with SCLC were randomized either to receive or not to receive subcutaneous heparin injections for 5 weeks at effective ...
journal_title:Cancer
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1002/1097-0142(19940701)74:1<38::aid-cncr282074
更新日期:1994-07-01 00:00:00
abstract:BACKGROUND:In less than a century, lung cancer has progressed from a medical curiosity to the most deadly of all malignant diseases on our planet. Because cigarette smoking is responsible for the existing global lung cancer epidemic, policy initiatives have focused almost exclusively on primary prevention. There is no ...
journal_title:Cancer
pub_type: 杂志文章,评审
doi:10.1002/1097-0142(20001201)89:11+<2422::aid-cncr16
更新日期:2000-12-01 00:00:00
abstract:BACKGROUND:Disruption of the lymphatic circulation through breast carcinoma-associated axillary lymph node dissection, with or without radiation therapy, reportedly is the most common cause of lymphedema in developed countries. There is no cure for breast carcinoma-associated lymphedema. Although intermittent pneumatic...
journal_title:Cancer
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1002/cncr.10976
更新日期:2002-12-01 00:00:00
abstract::Patients with cancer experience a much higher than expected incidence of thromboembolic disorders, commonly referred as Trousseau syndrome. Although this association has been well documented, the etiology of the hypercoagulable state is not known. The expression on tumor cells of tissue factor (TF), a membrane-bound l...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19920901)70:5<1194::aid-cncr2820
更新日期:1992-09-01 00:00:00
abstract:BACKGROUND:To define the clinicopathologic and prognostic features of patients with human T-cell lymphotropic virus type-1 (HTLV-1)-associated adult T-cell leukemia/lymphoma (ATLL) in North America, standard criteria were used to identify patients with ATLL. METHODS:Statistical analyses used included descriptive stati...
journal_title:Cancer
pub_type: 杂志文章,多中心研究
doi:10.1002/cncr.25147
更新日期:2010-07-15 00:00:00
abstract:BACKGROUND:Nonsteroidal anti-inflammatory drugs (NSAIDs) may prevent the development of cancer by inhibiting cyclooxygenase (COX) enzymes, which are involved in carcinogenesis. Therefore, the authors of this report examined the association between NSAID use and the risk of squamous cell carcinoma (SCC), basal cell carc...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.27406
更新日期:2012-10-01 00:00:00
abstract:BACKGROUND:Most cases of granulosa cell tumor of the ovary are characterized by relatively good outcome; however, some tumors behave aggressively, and some tend to recur many years after the initial diagnosis. Because DNA ploidy has been shown to predict biologic behavior better than conventional prognostic variables i...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19950501)75:9<2295::aid-cncr2820
更新日期:1995-05-01 00:00:00
abstract:BACKGROUND:Tamoxifen and aminoglutethimide are two hormone therapies reported to be effective palliative approaches for patients with metastatic breast cancer. The current trial was designed to evaluate their relative therapeutic effectiveness. METHODS:Two hundred forty-nine postmenopausal women with advanced breast c...
journal_title:Cancer
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1002/1097-0142(19940115)73:2<354::aid-cncr28207
更新日期:1994-01-15 00:00:00
abstract:BACKGROUND:The National Lung Screening Trial (NLST), which was conducted between 2002 and 2009, demonstrated that screening with low-dose computed tomography (LDCT) reduced lung cancer mortality by 20% among screening-eligible populations compared with chest x-ray. In this article, the authors provide an estimate of th...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.27813
更新日期:2013-04-01 00:00:00
abstract::Thyroglobulin messenger RNA (mRNA) was located and quantified in tissue sections of differentiated human thyroid cancers by in situ hybridization using cloned complementary DNA probes. The cells of the well-differentiated follicular and papillary forms contained similar levels of thyroglobulin mRNA, corresponding to a...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19850715)56:2<345::aid-cncr28205
更新日期:1985-07-15 00:00:00
abstract:BACKGROUND:Secondary acute myeloid leukemia (AML) after treatment with epipodophyllotoxins is being observed with increased frequency. Therapeutic options are limited for patients with secondary AML and the role of bone marrow transplantation is unclear. METHODS:The authors report the treatment outcome of a cohort of ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/(sici)1097-0142(19970301)79:5<1049::aid-cn
更新日期:1997-03-01 00:00:00
abstract::The authors evaluated specific gamma-GTP isoenzyme (specific gamma-GTP) found in sera of patients with hepatocellular carcinoma (HCC). In addition to band II and II' which had been reported in our previous publication, band I' also had a high specificity for HCC. One or more of these bands were detectable in 109 (55%)...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19830115)51:2<327::aid-cncr28205
更新日期:1983-01-15 00:00:00
abstract::Multifocal osteosarcoma with unique patho-biological features in a 23-year old white male is reported. The natural history and classification of multiple osteosarcomas are reviewed. A proposal is presented for evaluation of the multicentric origin in future cases. ...
journal_title:Cancer
pub_type: 杂志文章,评审
doi:10.1002/1097-0142(197911)44:5<1897::aid-cncr282044
更新日期:1979-11-01 00:00:00
abstract:BACKGROUND:Although delay to diagnosis after a breast screening abnormality causes anxiety, its effect on prognosis is unknown. METHODS:Using pooled data from five Canadian organized breast cancer screening programs, the authors used unconditional logistic regression to evaluate the effect of delay to diagnosis on pro...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.10453
更新日期:2002-04-15 00:00:00
abstract:BACKGROUND:Despite the recognition of ionizing radiation as a causal risk factor for a variety of solid tumors (including brain tumors), to date, such an association with pituitary adenoma (PA) has not been demonstrated. METHODS:To evaluate a possible association between past exposure to radiation and the occurrence o...
journal_title:Cancer
pub_type: 杂志文章,评审
doi:10.1002/cncr.10667
更新日期:2002-07-15 00:00:00
abstract::Blood vessel invasion and axillary lymph node involvement were examined in 175 breast cancer patients. The incidence of blood vessel invasion was 35%. The presence of blood vessel invasion was highly associated with early disease recurrence. The association of poor prognosis with blood vessel invasion was independent ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19820901)50:5<962::aid-cncr28205
更新日期:1982-09-01 00:00:00
abstract:BACKGROUND:Vascular endothelial growth factor (VEGF) signaling is a target for antiangiogenic cancer therapy. The authors have previously observed that up to 40% of vessels in colorectal carcinoma (CRC) tumors are negative for VEGF receptor 2 (VEGFR2) expression. Differential activity of transforming growth factor beta...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.26247
更新日期:2011-12-15 00:00:00
abstract::The diagnosis and grading of chondrosarcoma of bone is best established by a complementary study of its cytology, as observed in smeared preparations, and of its tissue structure and relationship to the host bone, as observed in histologic sections. Smeared preparations demonstrate the cytologic features of chondrosar...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19800201)45:3<582::aid-cncr28204
更新日期:1980-02-01 00:00:00
abstract:BACKGROUND:Glioblastoma, which is the most malignant brain tumor, remains incurable and almost always causes death. As a new treatment strategy, the combination of all-trans retinoic acid (ATRA) and paclitaxel was explored for controlling the growth of glioblastoma U87MG xenografts. METHODS:Human glioblastoma U87MG xe...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.23223
更新日期:2008-02-01 00:00:00
abstract::The livers of 345 autopsy cases of chronic liver disease were examined for macroregenerative nodule (MRN), a large nodular lesion more than 10 mm in diameter. A total of 86 lesions of MRN was found in 49 cases (14.2%): 32 were from 191 cases of hepatocellular carcinoma (HCC), 16 were from 148 cases of cirrhosis only, ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19880101)61:1<99::aid-cncr282061
更新日期:1988-01-01 00:00:00
abstract::Primary splenic angiosarcomas are rare neoplasms. The diagnosis can only be made at surgery. Splenectomy prior to rupture prolongs survival. An unusual case report is presented and the literature reviewed. ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19850401)55:7<1625::aid-cncr2820
更新日期:1985-04-01 00:00:00
abstract:LAY SUMMARY:Cancer has substantial economic impacts for patients, their families and/or caregivers, employers, and the health care system. However, there is only limited understanding of how economic issues can affect access to cancer care services and the receipt of high-quality cancer care. Health economics research ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.33343
更新日期:2020-11-25 00:00:00
abstract:BACKGROUND:Interferon is approved for adjuvant treatment of patients with stage IIB/III melanoma. The identification of predictive markers that would permit selection of patients would be beneficial. Specific human leukocyte antigen (HLA) class I and II antigens have previously shown an association with response to the...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.25211
更新日期:2010-09-15 00:00:00