Combination of paclitaxel and carboplatin as second-line therapy for patients with metastatic melanoma.

abstract：:One hundred eighty-three patients with malignant skeletal (83) or soft tissue sarcoma (100) were entered into the multimodality preoperative limb salvage protocol. Local recurrences were observed in 5 of 183 (2.7%). Six patients required amputation because of complications, and 13 patients died within 1 year from meta...

journal_title：Cancer

authors： Eilber FR,Morton DL,Eckardt J,Grant T,Weisenburger T

更新日期：1984-06-15 00:00:00

abstract：BACKGROUND:The incidence of metastasis to the thyroid gland in autopsy series varies from 1.25% to 24%. Metastasis to the thyroid gland is usually considered a terminal event, and the effectiveness of conventional treatment has been questioned. The authors assessed the effects of current methods of diagnosis and treatm...

journal_title：Cancer

authors： Nakhjavani MK,Gharib H,Goellner JR,van Heerden JA

更新日期：1997-02-01 00:00:00

abstract：:Cytopathologists recognize that certain Pap smear findings are suspicious for endometrial pathology in menopausal women. To study their prognostic importance in the directed cervical smear, six parameters were used to evaluate smears for evidence of an endometrial lesion: the presence of (1) histiocytes, (2) multinucl...

journal_title：Cancer

authors： Zucker PK,Kasdon EJ,Feldstein ML

更新日期：1985-11-01 00:00:00

abstract：BACKGROUND:Non-Hodgkin lymphoma (NHL), the most common cancer of the lymphatic system, is of unknown etiology. The identification of etiologic factors in the onset of NHL is a key event that could facilitate the prevention and cure of this malignancy. Simian virus 40 (SV40) has been considered an oncogenic agent in the...

journal_title：Cancer

authors： Tognon M,Luppi M,Corallini A,Taronna A,Barozzi P,Rotondo JC,Comar M,Casali MV,Bovenzi M,D'Agostino A,Vinante F,Rigo A,Ferrarini I,Barbanti-Brodano G,Martini F,Mazzoni E

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND:The aim of the current study was to assess circulating levels of endogenous endostatin in patients with renal carcinoma and to determine the relationship of these levels to circulating levels of vascular endothelial growth factor (VEGF) and prognosis. METHODS:The authors prospectively studied 66 patients (4...

journal_title：Cancer

authors： Feldman AL,Alexander HR Jr,Yang JC,Linehan WM,Eyler RA,Miller MS,Steinberg SM,Libutti SK

更新日期：2002-10-15 00:00:00

abstract：:One hundred four endocrine tumors found in the body and tail of the pancreas of a patient with the Zollinger-Ellison syndrome (ZES) and multiple endocrine neoplasia (MEN-I) were investigated by immunohistochemistry for insulin, glucagon, somatostatin, pancreatic polypeptide (PP), and gastrin. The results for each tumo...

journal_title：Cancer

authors： Pilato FP,D'Adda T,Banchini E,Bordi C

更新日期：1988-05-01 00:00:00

abstract：BACKGROUND:The purpose of the current study was to test the hypothesis that a lower clinical TNM stage is associated with a higher rate of pathologic complete response (pathCR) in patients with esophageal carcinoma receiving preoperative chemoradiotherapy and to determine whether outcome after pathCR is related to clin...

journal_title：Cancer

authors： Rohatgi P,Swisher SG,Correa AM,Wu TT,Liao Z,Komaki R,Walsh GL,Vaporciyan AA,Rice DC,Roth JA,Ajani JA

更新日期：2005-12-01 00:00:00

abstract：:A case of a dermal nerve sheath myxoma arising in a digital nerve is reported. Similar tumors and its variants have been termed neurothekeoma, pacinian neurofibroma, bizarre cutaneous neurofibroma, and plexiform neurofibroma. The perineural sheath or the Schwann cell have been presumed to be the cell of origin by seve...

journal_title：Cancer

authors： Blumberg AK,Kay S,Adelaar RS

更新日期：1989-03-15 00:00:00

abstract：BACKGROUND:Epithelioid hemangioendothelioma (EHE) is a rare neoplasm of vascular origin that occurs in the liver and other organs; its etiology is unknown. METHODS:The authors analyzed the clinicopathologic and immunohistochemical features of 137 patients with EHE of the liver in an attempt to identify features that m...

journal_title：Cancer

authors： Makhlouf HR,Ishak KG,Goodman ZD

更新日期：1999-02-01 00:00:00

abstract：BACKGROUND:The objective of this study was to evaluate the correlation between intratumoral blood flow as assessed by color Doppler ultrasound with stage, tumor grade, depth of invasion, and lymph node metastasis in endometrial carcinoma and determine its clinical usefulness. METHODS:Sixty-six patients with endometria...

journal_title：Cancer

authors： Cheng WF,Chen TM,Chen CA,Wu CC,Huang KT,Hsieh CY,Hsieh FJ

更新日期：1998-05-15 00:00:00

abstract：:The remaining tissue of the tracheobronchial tree from 210 men who died from lung cancer was studied to compare the histologic alterations leading to further sites of primary cancer. These men were uranium miners matched with nonminers for age and smoking habits. In the examination of a total of 28,928 cross-sections ...

journal_title：Cancer

authors： Auerbach O,Saccomanno G,Kuschner M,Brown RD,Garfinkel L

更新日期：1978-08-01 00:00:00

abstract：BACKGROUND:Alveolar soft part sarcoma (ASPS), chondrosarcoma (CS), chordoma, epithelioid sarcoma, and solitary fibrous tumor (SFT) are malignant tumors that are relatively resistant to chemotherapy and for which more effective drug therapy is needed. METHODS:The 5 listed subtypes were enrolled into a single indolent s...

journal_title：Cancer

authors： Schuetze SM,Bolejack V,Choy E,Ganjoo KN,Staddon AP,Chow WA,Tawbi HA,Samuels BL,Patel SR,von Mehren M,D'Amato G,Leu KM,Loeb DM,Forscher CA,Milhem MM,Rushing DA,Lucas DR,Chugh R,Reinke DK,Baker LH

更新日期：2017-01-01 00:00:00

abstract：:A case report is presented, believed to be the first documented example of pleomorphic rhabdomyosarcoma developing in the larynx of a child. A review of the literature then follows, with evaluation of the epidemiology, treatment options, and survival of patients with this disease. Cure of this malignancy is more likel...

journal_title：Cancer

authors： Dodd-o JM,Wieneke KF,Rosman PM

更新日期：1987-03-01 00:00:00

abstract：:Pretreatment biopsy material of 82 cases of follicular lymphoma of lymph node origin was reviewed. According to the amount of small lymphocytes in the parafollicular lymphoid tissue (PSL), tumors were classified: PSL++, abundant lymphocytes with prominent postcapillary venules; PSL+, a number of lymphocytes readily re...

journal_title：Cancer

authors： Ree HJ,Leone LA

更新日期：1978-04-01 00:00:00

abstract：:Local and systemic toxicities associated with hepatic arterial infusion of human recombinant tumor necrosis factor (rTNF) were studied in healthy adult mongrel dogs. The animals received saline containing human serum albumin with or without rTNF (0.02, 0.2, or 2.0 mg/m2). Arteriograms were made, and blood samples were...

journal_title：Cancer

authors： Ohkawa S,Wright KC,Mahajan H,Mavligit GM,Wallace S

更新日期：1989-06-01 00:00:00

abstract：:Retinoblastoma should not be considered as the exceptional childhood cancer that shows dominant inheritance, but rather as the typical childhood cancer that embraces a prezygotic and postzygotic subgroup. Postzygotic cases are conceived as involving mutation as a first step too, but with the mutation in somatic rather...

journal_title：Cancer

authors： Knudson AG Jr

更新日期：1975-03-01 00:00:00

abstract：:Flow cytometry examinations (FCM) were carried out on 110 bladder irrigation specimens from 84 urologic outpatients who had had prior conservative treatment for low stage bladder tumors. The specimens were easily obtained, and adequately cellular in all cases. Of 60 examinations on patients with no cytoscopic abnormal...

journal_title：Cancer

authors： Devonec M,Darzynkiewicz Z,Kostyrka-Claps ML,Collste L,Whitmore WF Jr,Melamed MR

更新日期：1982-01-01 00:00:00

abstract：:A case-referent study on soft tissue sarcomas (STS) was conducted, to see if previous findings regarding an association between exposure to phenoxyacetic acids or chlorophenols and this tumor type could be reproduced. Fifty-five male STS patients were thereby compared with 220 living and 110 dead population-based refe...

journal_title：Cancer

authors： Hardell L,Eriksson M

更新日期：1988-08-01 00:00:00

abstract：BACKGROUND:In this prospective study, the authors evaluated potential treatment toxicity and progression-free survival in patients with low-grade glioma who received treatment with proton radiation therapy. METHODS:Twenty patients with World Health Organization grade 2 glioma who were eligible for radiation therapy we...

journal_title：Cancer

authors： Shih HA,Sherman JC,Nachtigall LB,Colvin MK,Fullerton BC,Daartz J,Winrich BK,Batchelor TT,Thornton LT,Mancuso SM,Saums MK,Oh KS,Curry WT,Loeffler JS,Yeap BY

更新日期：2015-05-15 00:00:00

abstract：:Five patients with hepatocellular carcinoma in the caudate lobe were evaluated. Computed tomography (CT) scan and/or angiography clearly demonstrated multiple intrahepatic metastases in four (80%), and tumor thrombi in the portal vein in two (40%), and in the inferior vena cava in one. Even though there was no recogni...

journal_title：Cancer

authors： Takayasu K,Muramatsu Y,Shima Y,Goto H,Moriyama N,Yamada T,Makuuchi M,Kaneko A,Itabashi M,Shimamura Y

更新日期：1986-10-01 00:00:00

abstract：BACKGROUND:Lung carcinoma remains the major cause of cancer death in North America and is even more common among military veterans. The objective of this study was to determine whether there were differences in the characteristics and survival of Pennsylvania patients with lung carcinoma in the Veterans Administration ...

journal_title：Cancer

authors： Campling BG,Hwang WT,Zhang J,Thompson S,Litzky LA,Vachani A,Rosen IM,Algazy KM

更新日期：2005-08-15 00:00:00

abstract：BACKGROUND:Atypical and anaplastic meningiomas tend to recur and to invade adjacent brain, bone, and skin. They also can metastasize to extracranial organs such as the lung, liver, or bone, causing death. Recent reports have indicated that allelic deletion of chromosome 1p is associated with malignant progression of me...

journal_title：Cancer

authors： Ishino S,Hashimoto N,Fushiki S,Date K,Mori T,Fujimoto M,Nakagawa Y,Ueda S,Abe T,Inazawa J

更新日期：1998-07-15 00:00:00

abstract：BACKGROUND:Recent studies have shown that multiple cytokines are secreted by ovarian epithelial cancer cells. Previous studies have shown that the cancer cell lines secrete macrophage colony-stimulating factor (M-CSF), granulocyte-macrophage colony-stimulating factor (GM-CSF), interleukin-1 (IL-1), interleukin-6 (IL-6)...

journal_title：Cancer

authors： Moradi MM,Carson LF,Weinberg B,Haney AF,Twiggs LB,Ramakrishnan S

更新日期：1993-10-15 00:00:00

abstract：:Seventeen patients were given DTIC, 200 mg/m2/day in five-day courses every four to six weeks. In four patients (stage II) treated on an adjuvant basis, tumor recurrence has been verified in three. Four of the palliatively treated patients were also given DTIC by regional intra-arterial infusion with minimal positive ...

journal_title：Cancer

authors： Jönsson PE,Agrup G,Arnbjörnsson E,Hafström L,Rorsman H

更新日期：1980-01-15 00:00:00

abstract：BACKGROUND:Several studies have reported inverse associations between folate intake and colorectal carcinoma risk. Few were prospective studies and none evaluated the association between the intake of individual folate vitamers and colorectal carcinoma risk. METHODS:The aim of the current study was to investigate the ...

journal_title：Cancer

authors： Konings EJ,Goldbohm RA,Brants HA,Saris WH,van den Brandt PA

更新日期：2002-10-01 00:00:00

abstract：:The acquisition by tumor cells of the ability to metastasize is the critical event in the clinical course of most human neoplastic disease. While metastasis plays a pivotal role in the ultimate success of failure of therapy, it is in fact a result of a more insidious malignant process termed tumor progression. It is t...

journal_title：Cancer

authors： Frost P,Fidler IJ

更新日期：1986-07-15 00:00:00

abstract：:Sixty-four evaluable patients with hepatic metastases from colorectal carcinoma, who did not have evidence of extrahepatic disease, were treated with intrahepatic (IH) mitomycin C (M) after disease progression or intolerance to treatment with IH fluorodeoxyuridine (FUDR). Eleven patients (17%) had a partial response (...

journal_title：Cancer

authors： Schneider A,Kemeny N,Chapman D,Niedzwiecki D,Oderman P

更新日期：1989-12-01 00:00:00

abstract：:Malignant melanoma can potentially involve any organ system in the body once it metastasizes beyond the regional lymph nodes. A survey of the radiographic and associated clinical manifestations of metastatic melanoma is presented. The findings from 74 autopsies of patients who died of metastatic melanoma are included....

journal_title：Cancer

authors： Meyer JE

更新日期：1978-07-01 00:00:00

abstract：BACKGROUND:TRAIL (tumor necrosis factor related apoptosis-inducing ligand) is involved in tumor immune surveillance and, thus, may be a potential cancer therapy. TRAIL expression in the tumor microenvironment has been shown to impact cancer survival in multiple tumor types, including ovarian cancer. We studied TRAIL ex...

journal_title：Cancer

authors： Anees M,Horak P,El-Gazzar A,Susani M,Heinze G,Perco P,Loda M,Lis R,Krainer M,Oh WK

更新日期：2011-03-15 00:00:00

abstract：:DNA ploidy and percent of (%S-phase) S-phase cells were determined from the DNA content distribution of 21 benign and 76 malignant (69 primary, 7 metastatic) breast tumors using flow cytometry. All of the benign tumors were diploid, whereas 89% of the malignant tumors had measurable aneuploidy. Multiple stem-lines wer...

journal_title：Cancer

authors： Moran RE,Black MM,Alpert L,Straus MJ

更新日期：1984-10-15 00:00:00