Histologic findings in the tracheobronchial tree of uranium miners and non-miners with lung cancer.

abstract：BACKGROUND:Monoclonal antibodies have not been evaluated in metastasizing endocrine tumors, even though these lesions may induce severe morbidity of hormone excess in absence of considerable tumor burden. METHODS:A murine monoclonal antibody of the IgG2a subtype was generated by immunization with dispersed tumor cells...

journal_title：Cancer

authors： Juhlin C,Papanicolaou V,Arnberg H,Klareskog L,Lörelius LE,Rastad J,Oberg K,Akerström G

更新日期：1994-03-01 00:00:00

abstract：:Unraveling cancer-associated molecular defects is crucial for further pharmacological targeting. Although novel techniques are being developed to elucidate genomic, proteomic, and transcriptomic alterations, the map of protein interactions and aberrations in normal but also in malignant cells is still obscure. It has ...

journal_title：Cancer

authors： Karamouzis MV,Papavassiliou AG

更新日期：2014-02-01 00:00:00

abstract：:The case of hepatocellular carcinoma (HCC) with foci of hepatoblastoma in a 7-year-old boy, the son of a hepatitis B surface antigen (HBsAg) carrier mother, is described. Twelve other malignant liver tumors in children were tumors in children were also reviewed for HBsAg and hepatitis B core antigen (HBcAg). Both were...

journal_title：Cancer

authors： De Potter CR,Robberecht E,Laureys G,Cuvelier CA

更新日期：1987-08-01 00:00:00

abstract：BACKGROUND:High rates of locoregional recurrence have been reported from surgical series of locally advanced melanoma. In this study, the outcomes of patients treated with surgery and postoperative hypofractionated radiation therapy were reviewed to assess local recurrence and survival. METHODS:From 1989 to 1998, 174 ...

journal_title：Cancer

authors： Stevens G,Thompson JF,Firth I,O'Brien CJ,McCarthy WH,Quinn MJ

更新日期：2000-01-01 00:00:00

abstract：:Complete spontaneous regression of high-grade malignant non-Hodgkin's lymphoma is extremely unusual. In this report the authors describe a complete spontaneous remission after surgical excisional biopsy of a small noncleaved cell malignant lymphoma (non-Burkitt's lymphoblastic lymphoma) of the tonsil in a 12-year-old ...

journal_title：Cancer

authors： Poppema S,Postma L,Brinker M,de Jong B

更新日期：1988-08-15 00:00:00

abstract：BACKGROUND:In the past 4 years, the weekly 24-hour infusion of high dose 5-fluorouracil (5-FU) and leucovorin in the treatment of patients with advanced gastric carcinoma has been prospectively studied at the authors' institution. This has enabled them to explore the possibility that the level of expression of thymidyl...

journal_title：Cancer

authors： Yeh KH,Shun CT,Chen CL,Lin JT,Lee WJ,Lee PH,Chen YC,Cheng AL

更新日期：1998-05-01 00:00:00

abstract：:The following case report describes a 22-year-old healthy man, non-smoker, non-drinker, who developed a squamous cell carcinoma of the buccal mucosa. The appearance of this unusual tumor in an unexpected clinical setting was unexplained until it was discovered that the patient had a lifetime habit of chewing plastic m...

journal_title：Cancer

authors： Casterline CL,Casterline PF,Jaques DA

更新日期：1977-04-01 00:00:00

abstract：BACKGROUND:Two types of correction for absorbed dose (D) estimates are described for clinical applications of internal emitters. The first is appropriate for legal and scientific reasons involving phantom-based estimates; the second is patient-specific and primarily intended for radioimmunotherapy (RIT). METHODS:The M...

journal_title：Cancer

authors： Williams LE,Liu A,Yamauchi DM,Lopatin G,Raubitschek AA,Wong JY

更新日期：2002-02-15 00:00:00

abstract：BACKGROUND:Breast conservation surgery (BCS) and mastectomy have equivalent survival outcomes for women with breast carcinoma, but treatment decisions are affected by many factors. The current study evaluated the impact of patient and physician factors on surgical decision-making. METHODS:Statistical analyses were per...

journal_title：Cancer

authors： Chagpar AB,Studts JL,Scoggins CR,Martin RC 2nd,Carlson DJ,Laidley AL,El-Eid SE,McGlothin TQ,Noyes RD,McMasters KM

更新日期：2006-04-01 00:00:00

abstract：BACKGROUND:Gene expression profiling should be applicable to needle biopsy samples if microarray technology is to become practically useful for clinical research or management of breast carcinoma. This study compared gene expression profiles derived from fine-needle aspiration biopsy (FNAB) and from core needle biopsy ...

journal_title：Cancer

authors： Symmans WF,Ayers M,Clark EA,Stec J,Hess KR,Sneige N,Buchholz TA,Krishnamurthy S,Ibrahim NK,Buzdar AU,Theriault RL,Rosales MF,Thomas ES,Gwyn KM,Green MC,Syed AR,Hortobagyi GN,Pusztai L

更新日期：2003-06-15 00:00:00

abstract：BACKGROUND:The current study determined the efficacy and toxicity of weekly paclitaxel in combination with estramustine phosphate (EMP) in patients with androgen-independent prostate carcinoma (AIPC). METHODS:Patients with progressive AIPC received 90 mg/m2 paclitaxel by 1-hour intravenous infusion weekly for 3 weeks,...

journal_title：Cancer

authors： Vaughn DJ,Brown AW Jr,Harker WG,Huh S,Miller L,Rinaldi D,Kabbinavar F

更新日期：2004-02-15 00:00:00

abstract：:The properties of two classes of nonhistone nuclear proteins (NHNP) whose appearance has been correlated with the process of carcinogenesis in the colonic epithelium of rats given 1,2-dimethylhydrazine (DMH) have been investigated. NHNP isolated from adenocarcinomas of the colon were tested for their binding to homolo...

journal_title：Cancer

authors： Boffa LC,Allfrey VG

更新日期：1977-11-01 00:00:00

abstract：:Primary splenic angiosarcomas are rare neoplasms. The diagnosis can only be made at surgery. Splenectomy prior to rupture prolongs survival. An unusual case report is presented and the literature reviewed. ...

journal_title：Cancer

authors： Smith VC,Eisenberg BL,McDonald EC

更新日期：1985-04-01 00:00:00

abstract：:A study of 112 biopsy specimens from Danish oral leukoplakia patients and 145 biopsy specimens from Indian leukoplakia patients revealed a chevron-like keratinization of the epithelium in a number of cases. Clinically, this type of keratinization was often characterized by a pumice-like appearance. The clinical and hi...

journal_title：Cancer

authors： Pindborg JJ,Reibel J,Roed-Peterson B,Mehta FS

更新日期：1980-05-01 00:00:00

abstract：:Breast cancer specimens from 600 women were assayed for estrogen receptors (ER) using an immunocytochemical assay (ICA) employing the monoclonal antiestrophilin antibody H222 Sp gamma. Results showed significant correlation with biochemical ER determinations as well as with tumor grade and menopausal status. In 449 ca...

journal_title：Cancer

authors： Pertschuk LP,Kim DS,Nayer K,Feldman JG,Eisenberg KB,Carter AC,Rong ZT,Thelmo WL,Fleisher J,Greene GL

更新日期：1990-10-15 00:00:00

abstract：:A case of pancreatoblastoma, arising in the tail of the pancreas with metastases to the right radius, in an 8-year-old boy is reported. The serum alpha-fetoprotein (AFP) level was over 13 times the normal value before surgery, but returned to normal after removal of the primary tumor. Furthermore, AFP was detected in ...

journal_title：Cancer

authors： Iseki M,Suzuki T,Koizumi Y,Hirose M,Laskin WB,Nakazawa S,Ohaki Y

更新日期：1986-05-01 00:00:00

abstract：BACKGROUND:Chemotherapy intensification may lead to new forms of toxicity such as hemolytic uremic syndrome. METHODS:Three patients are described who developed this complication 4 to 6 months after high dose chemotherapy followed by autologous stem cell support. The literature on this subject is reviewed. RESULTS:One...

journal_title：Cancer

authors： van der Lelie H,Baars JW,Rodenhuis S,van Dijk MA,de Glas-Vos CW,Thomas BL,van Oers RH,von dem Borne AE

更新日期：1995-12-01 00:00:00

abstract：BACKGROUND:The FHIT gene, located at human chromosome 3p14.2, frequently is deleted in a number of human tumors, including breast carcinoma. Its protein product (Fhit) is presumed to have tumor suppressor function. Loss of expression of a tumor suppressor gene is an important step in tumor progression from premalignant...

journal_title：Cancer

authors： Gatalica Z,Lele SM,Rampy BA,Norris BA

更新日期：2000-03-15 00:00:00

abstract：:A 49-year-old white woman with refractory anemia subsequently developed acute myelomonocytic leukemia with paraproteinemia 12 months later. The paraprotein was characterized as immunoglobulin G, type kappa, and the Bence Jones protein as free kappa chains. Further studies, including electron microscopy, cytochemistry,...

journal_title：Cancer

authors： Law IP,Koch FJ,Cannon GB,Herberman RB,Oldham RK

更新日期：1976-03-01 00:00:00

abstract：BACKGROUND:: Although patients with chronic pancreatitis (CP) have an increased risk of pancreatic cancer (PanCa), the timely detection of PanCa often is difficult, because the symptoms of CP and PanCa are very similar. Moreover, secondary inflammation may be identified in PanCa, further complicating diagnosis. To impr...

journal_title：Cancer

authors： Liggett T,Melnikov A,Yi QL,Replogle C,Brand R,Kaul K,Talamonti M,Abrams RA,Levenson V

更新日期：2010-04-01 00:00:00

abstract：BACKGROUND:Prostate specific antigen (PSA) is useful as a tumor marker for monitoring patients with prostate cancer after definitive therapy. Limitations have been noted when PSA was used for the early detection of prostate cancer. The use of prostate specific antigen density [PSAD = PSA (ng/ml)/prostate volume (cc)] h...

journal_title：Cancer

authors： Bretton PR,Evans WP,Borden JD,Castellanos RD

更新日期：1994-12-01 00:00:00

abstract：BACKGROUND:RUNX3 is a tumor suppressor that plays important roles in cell proliferation, apoptosis, and metastasis. The authors investigated the role of RUNX3 in melanoma pathogenesis and analyzed the prognostic impact of RUNX3 expression in a large series of melanoma patients. METHODS:Two sets of tissue microarrays w...

journal_title：Cancer

authors： Zhang Z,Chen G,Cheng Y,Martinka M,Li G

更新日期：2011-06-15 00:00:00

abstract：:Formal cancer survivorship care is a growing focus internationally. This article provides a broad overview of the national strategies currently in progress for the development of survivorship programs and care plans within the United States and across Europe. The different approaches taken in their implementation, sta...

journal_title：Cancer

authors： McCabe MS,Faithfull S,Makin W,Wengstrom Y

更新日期：2013-06-01 00:00:00

abstract：BACKGROUND:The current study was conducted to examine gender differences in the effect of grief reactions and burnout on emotional distress among clinical oncologists. METHODS:The participants included a convenience sample of 178 oncologists from Israel (52 of whom were women) and Canada (48 of whom were women). Oncol...

journal_title：Cancer

authors： Granek L,Krzyzanowska MK,Nakash O,Cohen M,Ariad S,Barbera L,Levy R,Ben-David M

更新日期：2016-12-01 00:00:00

abstract：:A case of squamous cell carcinoma of the tongue in a 26-year-old man developing nine years after renal transplantation is presented. This is the first such case to be reported. Within seven months, widespread tumor metastases resulted in death. Pathologic examination of the transplanted kidney demonstrated neither re-...

journal_title：Cancer

authors： Lee YW,Gisser SD

更新日期：1978-01-01 00:00:00

abstract：BACKGROUND:Prostate-specific antigen (PSA) screening for prostate cancer has high risks of overdiagnosis, particularly among older men, and reports from screening trials indicate that it saves few lives after 11 to 13 years of follow-up. New clinical guidelines recommend against PSA screening for all men or for men age...

journal_title：Cancer

authors： Gulati R,Tsodikov A,Etzioni R,Hunter-Merrill RA,Gore JL,Mariotto AB,Cooperberg MR

更新日期：2014-11-15 00:00:00

abstract：:The diagnosis of malignant melanoma is based on clinical grounds and a properly performed biopsy, preferably excision, so that the type of melanoma and the thickness can be assessed by methods described by Clark and Breslow. These facilitate clinical and pathologic staging. Excisions with conservative margins for thin...

journal_title：Cancer

authors： Harris MN,Shapiro RL,Roses DF

更新日期：1995-01-15 00:00:00

abstract：:Two cases of occult seminoma were observed which showed left-sided lymph node metastases without clinically demonstrable testicular tumors. The peculiar histology of the lymph node metastases, namely PAS-positive tumor cells with clear cytoplasm together with a granulomatous stromal reaction, was highly suggestive of ...

journal_title：Cancer

authors： Richter HJ,Leder LD

更新日期：1979-07-01 00:00:00

abstract：:We have reviewed the records of 76 patients with Stage I or II extranodal non-Hodgkin's lymphoma who were referred to the Division of Radiation Oncology, Mallinckrodt Institute of Radiology, during the years 1964 through 1974. The histologic slides were reviewed in the 67 cases in which they were available. Forty-thre...

journal_title：Cancer

authors： Mill WB,Lee FA,Franssila KO

更新日期：1980-02-15 00:00:00

abstract：:A classification for childhood brain tumors based upon revision of nomenclature of all brain tumors published by the World Health Organization (WHO) in 1979 is proposed. Applicability of the WHO classification scheme was tested in a combined study of the clinical and pathologic features of approximately 3300 brain tum...

journal_title：Cancer

authors： Rorke LB,Gilles FH,Davis RL,Becker LE

更新日期：1985-10-01 00:00:00