Lymph node metastases with PAS-positive tumor cells and massive epithelioid granulomatous reaction as diagnostic clue to occult seminoma.

Abstract:

:Two cases of occult seminoma were observed which showed left-sided lymph node metastases without clinically demonstrable testicular tumors. The peculiar histology of the lymph node metastases, namely PAS-positive tumor cells with clear cytoplasm together with a granulomatous stromal reaction, was highly suggestive of seminoma. Despite lack of testicular enlargement in both cases, a left-sided orchiectomy was done. Histologically, intratubular seminomas were found which confirmed the original diagnostic suspicions derived from the morphology of the lymph node metastases. It is concluded, therefore, that in the case of lymph node metastases with the above-mentioned structure, occult seminoma should always be taken into consideration. Because of the modern beneficial therapeutic implications, detection of occult seminoma is very important.

journal_name

Cancer

journal_title

Cancer

authors

Richter HJ,Leder LD

doi

10.1002/1097-0142(197907)44:1<245::aid-cncr2820440

subject

Has Abstract

pub_date

1979-07-01 00:00:00

pages

245-9

issue

1

eissn

0008-543X

issn

1097-0142

journal_volume

44

pub_type

杂志文章

相关文献

CANCER文献大全
  • A phase II study of irinotecan (CPT-11) in patients with advanced squamous cell carcinoma of the cervix.

    abstract:BACKGROUND:This study was conducted to determine the efficacy and safety of irinotecan (CPT-11) as second-line therapy in patients with advanced cervical carcinoma. METHODS:Sixteen patients with platinum-resistant squamous cell carcinoma were treated with CPT-11 as second-line therapy. CPT-11 was administered in repea...

    journal_title:Cancer

    pub_type: 临床试验,杂志文章

    doi:10.1002/(sici)1097-0142(19980115)82:2<334::aid-cnc

    authors: Irvin WP,Price FV,Bailey H,Gelder M,Rosenbluth R,Durivage HJ,Potkul RK

    更新日期:1998-01-15 00:00:00

  • A phase II trial of extracorporeal plasma immunoadsorption of patient plasma with PROSORBA columns for treating metastatic breast cancer.

    abstract:BACKGROUND:Circulating immune complexes (CIC) have been implicated as a cause of malignancy-associated immunosuppression and disease progression. Previous attempts to remove CIC by pheresis or immunoadsorption over a Staphylococcus aureus protein A column have resulted in a few clinical responses, however the relations...

    journal_title:Cancer

    pub_type: 临床试验,杂志文章

    doi:10.1002/1097-0142(19950415)75:8<2099::aid-cncr2820

    authors: Fennelly DW,Norton L,Sznol M,Hakes TB

    更新日期:1995-04-15 00:00:00

  • Prenatal and perinatal risk factors for neuroblastoma. A case-control study.

    abstract::Neuroblastoma is the most common neoplasm in children less than 1 year of age and has one of the earliest incidence peaks of all childhood cancers. Using birth registration data, a matched case-control study was undertaken to investigate potential prenatal and perinatal risk factors. Ninety-seven neuroblastoma patient...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19880601)61:11<2202::aid-cncr282

    authors: Neglia JP,Smithson WA,Gunderson P,King FL,Singher LJ,Robison LL

    更新日期:1988-06-01 00:00:00

  • Rhabdomyosarcoma of the oral and paraoral region.

    abstract::Oral rhabdomyosarcoma (RMS) was studied by analysis of eight such cases which presented over a 25-year period. Rhabdomyosarcoma was the fourth most common oral sarcoma (7.5%) from this period after osteosarcoma (32%), fibrosarcoma (19%), and chondrosarcoma (9%). In patients younger than 20 years, RMS was the second mo...

    journal_title:Cancer

    pub_type: 杂志文章,评审

    doi:10.1002/1097-0142(19890301)63:5<963::aid-cncr28206

    authors: Peters E,Cohen M,Altini M,Murray J

    更新日期:1989-03-01 00:00:00

  • Primary malignant fibrous histiocytoma of bone.

    abstract::A review of over 400 primary bone tumors yielded 11 lesions with features allowing classification as malignant fibrous histiocytoma on a purely histological basis. Correlation with roentgenograms and clinical data indicated that these tumors occurred as osteolytic lesions associated with a high incidence of pathologic...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.2820360925

    authors: Spanier SS,Enneking WF,Enriquez P

    更新日期:1975-12-01 00:00:00

  • Defining a molecular phenotype for benign and malignant parathyroid tumors.

    abstract:BACKGROUND:It is frequently difficult to establish histologically whether a parathyroid tumor is a parathyroid carcinoma, parathyromatosis, or an atypical adenoma. The authors asked whether these tumors have a distinctive molecular profile, whether benign tumors could be distinguished from malignant tumors, and whether...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.24037

    authors: Fernandez-Ranvier GG,Khanafshar E,Tacha D,Wong M,Kebebew E,Duh QY,Clark OH

    更新日期:2009-01-15 00:00:00

  • Adoptive immunotherapy with allogeneic Epstein-Barr virus (EBV)-specific cytotoxic T-lymphocytes for recurrent, EBV-positive Hodgkin disease.

    abstract:BACKGROUND:It has been shown that adoptive immunotherapy with Epstein-Barr virus (EBV)-specific cytotoxic T-lymphocytes (CTL) is effective for the treatment of EBV-induced lymphoproliferative disease in stem cell transplantation recipients and organ transplantation recipients. The role of EBV CTL in other tumors for wh...

    journal_title:Cancer

    pub_type: 临床试验,杂志文章

    doi:10.1002/cncr.20188

    authors: Lucas KG,Salzman D,Garcia A,Sun Q

    更新日期:2004-05-01 00:00:00

  • Factors influencing survival of children with nonmetastatic neuroblastoma.

    abstract::A randomized study was designed to determine the effect of intermittent oral cyclophosphamide on the rate of metastases in children with localized and regional neuroblastoma. Secondary objectives of the study were to determine the value of the proposed staging system, to measure the influence of the peripheral lymphoc...

    journal_title:Cancer

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1002/1097-0142(197608)38:2<661::aid-cncr2820380

    authors: Evans AE,Albo V,D'Angio GJ,Finklestein JZ,Leiken S,Santulli T,Weiner J,Hammond GD

    更新日期:1976-08-01 00:00:00

  • Factors predicting prostate cancer upgrading on magnetic resonance imaging-targeted biopsy in an active surveillance population.

    abstract:BACKGROUND:The objective of this study was to create a nomogram model integrating clinical and multiparametric magnetic resonance imaging (MP-MRI)-based variables to predict prostate cancer upgrading in a population of active surveillance (AS) patients. METHODS:Prostate cancer patients on AS who underwent MP-MRI with ...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.30548

    authors: Lai WS,Gordetsky JB,Thomas JV,Nix JW,Rais-Bahrami S

    更新日期:2017-06-01 00:00:00

  • Assessment of reflex human papillomavirus DNA testing in patients with atypical endocervical cells on cervical cytology.

    abstract:BACKGROUND:Reflex human papillomavirus (HPV) testing for atypical squamous cells of undetermined significance (ASC-US) has improved the sensitivity and specificity in detecting high-grade squamous dysplasia (cervical intraepithelial neoplasia [CIN]2+). However, to the authors' knowledge there are no guidelines for perf...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.23639

    authors: Chen L,Yang B

    更新日期:2008-08-25 00:00:00

  • Trends in multiple myeloma presentation, management, cost of care, and outcomes in the Medicare population: A comprehensive look at racial disparities.

    abstract:BACKGROUND:Outcomes have improved significantly in multiple myeloma (MM), but racial disparities in health care access and survival exist. A comprehensive analysis exploring MM care and racial disparities is warranted. METHODS:Patients with MM from 1991 to 2010 in the Surveillance, Epidemiology, and End Results-Medica...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.31237

    authors: Ailawadhi S,Frank RD,Sharma M,Menghani R,Temkit M,Paulus S,Khera N,Hashmi S,Advani P,Swaika A,Paulus A,Aslam N,Sher T,Roy V,Colon-Otero G,Chanan-Khan A

    更新日期:2018-04-15 00:00:00

  • Multidisciplinary treatment of primary Ewing's sarcoma of bone. A 6-year experience of a European Cooperative Trial.

    abstract::The German Society of Pediatric Oncology in 1981 initiated the Cooperative Ewing's Sarcoma Study (CESS 81) using a four-drug combination of chemotherapy prior to definitive local control with surgery and/or radiation. From January 1, 1981 until February 28, 1985, 93 patients were registered at the trial office from 54...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19880101)61:1<23::aid-cncr282061

    authors: Jürgens H,Exner U,Gadner H,Harms D,Michaelis J,Sauer R,Treuner J,Voûte T,Winkelmann W,Winkler K

    更新日期:1988-01-01 00:00:00

  • Functional insulin receptors are overexpressed in thyroid tumors: is this an early event in thyroid tumorigenesis?

    abstract:BACKGROUND:Insulin receptor (IR), a member of the receptor tyrosine kinase family, is expressed in normal thyroid cells and affects thyroid cell proliferation and differentiation. METHODS:The authors measured IR content in benign and malignant thyroid tumors by three independent methods: a specific radioimmunoassay, 1...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/(sici)1097-0142(19990115)85:2<492::aid-cnc

    authors: Frittitta L,Sciacca L,Catalfamo R,Ippolito A,Gangemi P,Pezzino V,Filetti S,Vigneri R

    更新日期:1999-01-15 00:00:00

  • Studies on translocation of immunoglobulins across intestinal epithelium.

    abstract::The issue of how immunoglobulins are transported across the intestinal epithelium into the gut lumen was examined by immunohistocytochemical techniques. IgA, IgM, IgG and secretory component (SC) in human small intestine at light and electron microscopic levels were localized by the peroxidase-labeled antibody techniq...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(197711)40:5+<2497::aid-cncr28204

    authors: Brown WR

    更新日期:1977-11-01 00:00:00

  • Disease and treatment characteristics do not predict symptom occurrence profiles in oncology outpatients receiving chemotherapy.

    abstract:BACKGROUND:A large amount of interindividual variability exists in the occurrence of symptoms in patients receiving chemotherapy (CTX). The purposes of the current study, which was performed in a sample of 582 oncology outpatients who were receiving CTX, were to identify subgroups of patients based on their distinct ex...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.28699

    authors: Miaskowski C,Cooper BA,Melisko M,Chen LM,Mastick J,West C,Paul SM,Dunn LB,Schmidt BL,Hammer M,Cartwright F,Wright F,Langford DJ,Lee K,Aouizerat BE

    更新日期:2014-08-01 00:00:00

  • Religion, spirituality, and health outcomes in cancer: A case for a meta-analytic investigation.

    abstract::A growing body of research shows that a majority of patients with cancer report having religious and spiritual (R/S) beliefs, engaging in R/S behaviors, or deriving comfort from R/S experiences. These studies have been reviewed but not subjected to rigorous critical analysis. A meta-analytic approach is needed to prov...

    journal_title:Cancer

    pub_type: 杂志文章,meta分析

    doi:10.1002/cncr.29349

    authors: Salsman JM,Fitchett G,Merluzzi TV,Sherman AC,Park CL

    更新日期:2015-11-01 00:00:00

  • Quality of life and symptoms in a randomized trial of radiotherapy versus deferred treatment of localized prostate carcinoma.

    abstract:BACKGROUND:Treatment of localized prostate carcinoma (LPC) using radiotherapy (RT) can induce disturbances in a patient's quality of life (QOL) and urinary and intestinal function. Late symptoms and QOL were evaluated in a randomized trial between RT and deferred treatment (DT). METHODS:Quality of life was evaluated w...

    journal_title:Cancer

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1002/1097-0142(20011215)92:12<3111::aid-cncr101

    authors: Fransson P,Damber JE,Tomic R,Modig H,Nyberg G,Widmark A

    更新日期:2001-12-15 00:00:00

  • The two types of correction of absorbed dose estimates for internal emitters.

    abstract:BACKGROUND:Two types of correction for absorbed dose (D) estimates are described for clinical applications of internal emitters. The first is appropriate for legal and scientific reasons involving phantom-based estimates; the second is patient-specific and primarily intended for radioimmunotherapy (RIT). METHODS:The M...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.10290

    authors: Williams LE,Liu A,Yamauchi DM,Lopatin G,Raubitschek AA,Wong JY

    更新日期:2002-02-15 00:00:00

  • Risk assessment of patients with hematologic malignancies who develop fever accompanied by pulmonary infiltrates: a historical cohort study.

    abstract:BACKGROUND:The mortality rate associated with fever accompanied by pulmonary infiltrates after chemotherapy for hematologic malignancies remains higher than the corresponding rate associated with febrile neutropenia without pulmonary infiltrates. Nonetheless, few studies have focused on the factors that predict outcome...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.20406

    authors: Offidani M,Corvatta L,Malerba L,Marconi M,Bichisecchi E,Cecchini S,Manso E,Principi T,Gasparini S,Leoni P

    更新日期:2004-08-01 00:00:00

  • Changes in serum levels of Forssman-like antibody in patients with gastric cancer.

    abstract::Because Forssman antigen, one of the most well-known heteroantigens, has been noted in certain cancerous tissues, it would seem that the serum levels of the Forssman antibody of patients with these cancers would be low, owing to the absorption of the naturally occurring antibody by the Forssman antigen-containing canc...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19890415)63:8<1528::aid-cncr2820

    authors: Hirayama R,Hirokawa K,Takagi Y,Utsuyama M,Maejima S,Takemura K,Mishima Y,Makinodan T

    更新日期:1989-04-15 00:00:00

  • Application of distance matrices to define associations between acute toxicities in colorectal cancer patients receiving chemotherapy.

    abstract:BACKGROUND:Colorectal cancer patients undergoing chemotherapy (CT) are likely to experience multiple concurrent toxicities that, rather than appearing singularly, may be associated with one another. Graphic and tabular representations of distance matrices were used to identify associations between toxicities and to def...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.23182

    authors: Aprile G,Ramoni M,Keefe D,Sonis S

    更新日期:2008-01-15 00:00:00

  • Establishment of a new Hodgkin's cell line (HD-70) of B-cell origin.

    abstract::A new Hodgkin's cell line, designated HD-70, was established from the peripheral blood of a 69-year-old man with Hodgkin's disease of nodular sclerosing type. The cell line grows in a single cell suspension and has a doubling time of 28 hours. The cells have a round or irregular nucleus or multiple nuclei in relativel...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19920215)69:4<1034::aid-cncr2820

    authors: Kanzaki T,Kubonishi I,Eguchi T,Yano S,Sonobe H,Ohyashiki JH,Ohyashiki K,Toyama K,Ohtsuki Y,Miyoshi I

    更新日期:1992-02-15 00:00:00

  • Evaluation of an automated immunochemical fecal occult blood test for colorectal neoplasia detection in a Chinese population.

    abstract:BACKGROUND:Most commercial fecal occult blood tests (FOBT) used for colorectal carcinoma screening of Western populations are guaiac-based, manually developed, subjective, and sensitive to dietary components. Preliminary studies demonstrated the unsuitability of these tests for screening a Chinese population. The goal ...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.11369

    authors: Wong WM,Lam SK,Cheung KL,Tong TS,Rozen P,Young GP,Chu KW,Ho J,Law WL,Tung HM,Choi HK,Lee YM,Lai KC,Hu WH,Chan CK,Yuen MF,Wong BC

    更新日期:2003-05-15 00:00:00

  • Indomethacin-mediated enhancement of lymphocyte response to mitogens in healthy subjects and lung cancer patients.

    abstract::Indomethacin (prostaglandin synthetase inhibitor) was found to be capable of enhancing the mitogen-induced lymphocyte proliferative responses of healthy subjects and patients with lung cancer. A whole-blood culture technique was used. Indomethacin had no mitogenic activity. We observed a greater enhancement of lymphoc...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19801201)46:11<2416::aid-cncr282

    authors: Han T,Takita H

    更新日期:1980-12-01 00:00:00

  • The role of tumor resection in the treatment of glioblastoma multiforme in adults.

    abstract:BACKGROUND:The therapeutic impact of tumor resection is poorly defined. Therefore the current study was conducted. METHODS:A retrospective, 2-institutional study was conducted (1991-1994) to compare the treatment results of stereotactic biopsy plus radiation therapy (99 patients; tumor dose: 60 gray [Gy]) with those o...

    journal_title:Cancer

    pub_type: 杂志文章,多中心研究

    doi:

    authors: Kreth FW,Berlis A,Spiropoulou V,Faist M,Scheremet R,Rossner R,Volk B,Ostertag CB

    更新日期:1999-11-15 00:00:00

  • Wide local excision of recurrent breast cancer in the thoracic wall.

    abstract:BACKGROUND:Local recurrence is one of the major problems in treatment of breast cancer. Approximately 20% of patients who have radical or modified radical mastectomy have a local recurrence. METHODS:The records of 98 women with locally recurrent breast cancer treated with wide local excision, in the years 1983-1987, w...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19930801)72:3<774::aid-cncr28207

    authors: Dahlstrøm KK,Andersson AP,Andersen M,Krag C

    更新日期:1993-08-01 00:00:00

  • Urinary chorionic gonadotropin subunits and beta-core in nonpregnant women. A study of benign and malignant gynecologic disorders.

    abstract:BACKGROUND:The presence of urinary excretion products of human chorionic gonadotropin (hCG) has been proposed as a tumor marker. To ascertain the clinical value in gynecologic cancers, the authors studied 612 nonpregnant women. METHODS:Three different assays in four clinical groups were compared: no disease, benign di...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19930615)71:12<4124::aid-cncr282

    authors: Neven P,Iles RK,Lee CL,Hudson CN,Shepherd JH,Chard T

    更新日期:1993-06-15 00:00:00

  • Survival outcome of adjuvant chemotherapy in deficient mismatch repair stage III colon cancer.

    abstract:BACKGROUND:The prognostic impact of DNA mismatch repair (MMR) status remains controversial in patients with stage III colon cancer who are treated with adjuvant chemotherapy (AC). The aim of this study was to evaluate the survival outcome of AC in deficient mismatch repair (dMMR)/microsatellite instable (MSI) stage III...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.33049

    authors: Shaib WL,Zakka KM,Jiang R,Yan M,Alese OB,Akce M,Wu C,Behera M,El-Rayes BF

    更新日期:2020-09-15 00:00:00

  • Expression of c-myc oncogene product and ras family oncogene products in various human malignant lymphomas defined by immunohistochemical techniques.

    abstract::The authors studied the expression of c-myc and ras family oncogene products in 43 cases of malignant lymphoma (ML) using the immunoperoxidase method. Unfixed frozen sections of lymph nodes from four patients with Hodgkin's disease and 39 with non-Hodgkin's lymphoma, together with normal lymph nodes, were studied by t...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19881115)62:10<2085::aid-cncr282

    authors: Mitani S,Sugawara I,Shiku H,Mori S

    更新日期:1988-11-15 00:00:00

  • The prognostic significance of ploidy analysis in operable breast cancer.

    abstract::The nuclear DNA content of 98 operable breast cancers was determined by flow cytometric analysis using paraffin-embedded tissue. All patients were on follow-up and failure of treatment or recurrences were identified. DNA ploidy data in the form of ploidy status and DNA index (DI) has been correlated with various clini...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19911215)68:12<2612::aid-cncr282

    authors: Sharma S,Mishra MC,Kapur BM,Verma K,Nath I

    更新日期:1991-12-15 00:00:00