Multidisciplinary treatment of primary Ewing's sarcoma of bone. A 6-year experience of a European Cooperative Trial.

abstract：BACKGROUND:The expression of vascular endothelial growth factor (VEGF)-A isoforms (121, 165, 189, 206), VEGF-B, VEGF-C and VEGF-D in both experimental and clinical models of head and neck squamous cell carcinoma (HNSCC) was determined and correlated with conventional clinicopathologic parameters, with particular refere...

journal_title：Cancer

authors： O-charoenrat P,Rhys-Evans P,Eccles SA

更新日期：2001-08-01 00:00:00

abstract：BACKGROUND:The presence of urinary excretion products of human chorionic gonadotropin (hCG) has been proposed as a tumor marker. To ascertain the clinical value in gynecologic cancers, the authors studied 612 nonpregnant women. METHODS:Three different assays in four clinical groups were compared: no disease, benign di...

journal_title：Cancer

authors： Neven P,Iles RK,Lee CL,Hudson CN,Shepherd JH,Chard T

更新日期：1993-06-15 00:00:00

abstract：BACKGROUND:Children with acute lymphoblastic leukemia with multiple poor prognostic factors and who have a lymphomatous mass at diagnosis, whether of T- or non-T-immunophenotype, are at increased risk of short term remission and extramedullary recurrence, and are in need of better therapies. METHODS:Six hundred and ni...

journal_title：Cancer

authors： Steinherz PG,Gaynon PS,Breneman JC,Cherlow JM,Grossman NJ,Kersey JH,Johnstone HS,Sather HN,Trigg ME,Uckun FM,Bleyer WA

更新日期：1998-02-01 00:00:00

abstract：:Two hundred seventy-nine consecutive patients with Stage II osteogenic sarcoma of the appendicular skeleton treated between 1976 and 1986 were studied to identify predictors of long-term survival. Survival was 77% and 73% at 5 and 10 years, respectively, with continuously disease-free survival being 70% and 69%. On un...

journal_title：Cancer

authors： Glasser DB,Lane JM,Huvos AG,Marcove RC,Rosen G

更新日期：1992-02-01 00:00:00

abstract：BACKGROUND:Studies regarding different ethnic populations of children with Wilms' tumor (WT) in the U. S. have shown differences between age and gender incidence and the type of its precursor lesions (nephrogenic rests). To the authors' knowledge there are few reports in the literature regarding nephrogenic rests in a ...

journal_title：Cancer

authors： Mishra K,Mathur M,Logani KB,Kakkar N,Krishna A

更新日期：1998-11-15 00:00:00

abstract：BACKGROUND:Ewing sarcoma family of tumors (ESFTs) are the second most common bone tumor, that most often affects persons ages 3-40 years. The ESFTs rely on signaling through the insulin-like growth factor-1 receptor (IGF-1R) for growth and transformation. The current studies were performed to determine the levels of IG...

journal_title：Cancer

authors： Toretsky JA,Steinberg SM,Thakar M,Counts D,Pironis B,Parente C,Eskenazi A,Helman L,Wexler LH

更新日期：2001-12-01 00:00:00

abstract：:The development of monoclonal antibodies has led to renewed interest in the use of antibodies to treat malignant disease. Unfortunately, treatment with unmodified antibodies has been disappointing. Therapy with unmodified antibodies has been limited by the failure of host effector mechanisms to eliminate antibody-coat...

journal_title：Cancer

authors： Badger CC,Bernstein ID

更新日期：1986-07-15 00:00:00

abstract：BACKGROUND:Currently, there is very low-quality evidence available regarding benefit of surgical resection of the primary tumor (SRPT), in patients with stage IV colorectal cancer (CRC). In the absence of randomization, the reported benefit may reflect selection of younger and healthier patients with good performance s...

journal_title：Cancer

authors： Ahmed S,Leis A,Fields A,Chandra-Kanthan S,Haider K,Alvi R,Reeder B,Pahwa P

更新日期：2014-03-01 00:00:00

abstract：:Elevated serum levels of carcinoembryonic antigen (CEA) were found in 70% of 141 patients with advanced gastrointestinal (GI) cancers. Serial CEA measurements were performed on 70 patients before and during chemotherapy. The majority were treated with 5-FU and Methyl-CCNU (33 patients), 5-FU (19 patients), or 5-FU and...

journal_title：Cancer

authors： Al-Sarraf M,Baker L,Talley RW,Kithier K,Vaitkevicius VK

更新日期：1979-10-01 00:00:00

abstract：:The glucocorticoid receptor (GR) quantitation by a whole-cell assay and/or cytosol technique and the in vitro sensitivity to steroids have been assessed in peripheral blood cells from normal donors and patients with chronic lymphatic leukemia (CLL), acute lymphoblastic leukemia (ALL), lymphosarcoma cell leukemia (LSCL...

journal_title：Cancer

authors： Nanni P,Nicoletti G,Prodi G,Galli MC,De Giovanni C,Grilli S,Lollini PL,Gobbi M,Cavo M,Tura S

更新日期：1982-02-15 00:00:00

abstract：:A retrospective study of 702 patients with clinically positive nodes associated with squamous cell carcinoma of the oral cavity, supraglottic larynx, and hypopharynx observed from 1954 to 1968 was done. The policies of treatment for the neck were not standardized during those years. Three hundred eleven patients who s...

journal_title：Cancer

authors： Jesse RH,Fletcher GH

更新日期：1977-02-01 00:00:00

abstract：BACKGROUND:Despite its established benefits, palliative care (PC) is rarely utilized for hematopoietic stem cell transplant (HSCT) patients. We sought to examine transplant physicians' perceptions of PC. METHODS:We conducted a cross-sectional survey of transplant physicians recruited from the American-Society-for-Bloo...

journal_title：Cancer

authors： El-Jawahri A,LeBlanc TW,Burns LJ,Denzen E,Meyer C,Mau LW,Roeland EJ,Wood WA,Petersdorf E

更新日期：2018-12-01 00:00:00

abstract：:From the standpoint of chemotherapy, the first progress in the treatment of Hodgkin's disease was the identification of the activity of nitrogen mustard in the 1940's. The initial antitumor effect of the drug created a great excitement. However, when all patients later relapsed, there was subsequent dejection and skep...

journal_title：Cancer

authors： DeVita VT Jr,Lewis BJ,Rozencweig M,Muggia FM

更新日期：1978-08-01 00:00:00

abstract：BACKGROUND:Men who undergo radical prostatectomy (RP) are at long-term risk of biochemical recurrence (BCR). In this report, the authors have described a model capable of predicting BCR up to at least 15 years after RP that can adjust predictions according to the disease-free interval. METHODS:Cox regression was used ...

journal_title：Cancer

authors： Suardi N,Porter CR,Reuther AM,Walz J,Kodama K,Gibbons RP,Correa R,Montorsi F,Graefen M,Huland H,Klein EA,Karakiewicz PI

更新日期：2008-03-15 00:00:00

abstract：BACKGROUND:While the question of whether the trials of breast cancer screening have resulted in a reduction in breast cancer death has been the subject of much scrutiny, there has been less attention to the reduction in tumor size achieved by screening. METHODS:Size data for invasive breast tumors were assembled from ...

journal_title：Cancer

authors： Michaelson JS,Satija S,Kopans D,Moore R,Silverstein M,Comegno A,Hughes K,Taghian A,Powell S,Smith B

更新日期：2003-11-15 00:00:00

abstract：BACKGROUND:Methotrexate is a chemotherapeutic agent frequently utilized for the treatment of malignant, rheumatic, and pulmonary diseases. Although this agent has been extensively used for more than 45 years, there are few reports of immediate systemic hypersensitivity reactions. The reported immediate reactions includ...

journal_title：Cancer

authors： Alkins SA,Byrd JC,Morgan SK,Ward FT,Weiss RB

更新日期：1996-05-15 00:00:00

abstract：BACKGROUND:Insulin-like growth factor I (IGF-I) is a potent mitogen for breast cancer cells. The majority of IGF-I in plasma is bound to IGF binding proteins (IGFBPs), which modulate the biologic effects of IGF-I. METHODS:Plasma concentrations of IGF-I, IGFBP-I, and IGFBP-3 were compared between 40 postmenopausal brea...

journal_title：Cancer

authors： Lahti EI,Knip M,Laatikainen TJ

更新日期：1994-07-15 00:00:00

abstract：BACKGROUND:Single-walled carbon nanotubes (SWNTs) have remarkable physicochemical properties that may have several medical applications. The authors have discovered a novel property of SWNTs-heat release in a radiofrequency (RF) field-that they hypothesized may be used to produce thermal cytotoxicity in malignant cells...

journal_title：Cancer

authors： Gannon CJ,Cherukuri P,Yakobson BI,Cognet L,Kanzius JS,Kittrell C,Weisman RB,Pasquali M,Schmidt HK,Smalley RE,Curley SA

更新日期：2007-12-15 00:00:00

abstract：BACKGROUND:The influence of HER-2/neu on prognosis of breast cancer is controversial. The authors investigated by immunohistochemistry in node-positive disease the influence of the pattern of immunostaining (membranous or cytoplasmic) on outcome and the prognostic significance of this marker in patients receiving or no...

journal_title：Cancer

authors： Têtu B,Brisson J

更新日期：1994-05-01 00:00:00

abstract：BACKGROUND:A phase 1 trial was used to evaluate a combination of cisplatin, gemcitabine, and escalating doses of veliparib in patients with untreated advanced pancreatic ductal adenocarcinoma (PDAC) in 2 cohorts: a germline BRCA1/2-mutated (BRCA+) cohort and a wild-type BRCA (BRCA-) cohort. The aims were to determine t...

journal_title：Cancer

authors： O'Reilly EM,Lee JW,Lowery MA,Capanu M,Stadler ZK,Moore MJ,Dhani N,Kindler HL,Estrella H,Maynard H,Golan T,Segal A,Salo-Mullen EE,Yu KH,Epstein AS,Segal M,Brenner R,Do RK,Chen AP,Tang LH,Kelsen DP

更新日期：2018-04-01 00:00:00

abstract：BACKGROUND:Improvements in quality of life after treatment with recombinant human erythropoietin (rHuEPO) often have been reported in patients with end-stage renal disease. In patients with chronic anemia of cancer, comparatively few systemic investigations have been performed. METHODS:Various aspects of quality of li...

journal_title：Cancer

authors： Leitgeb C,Pecherstorfer M,Fritz E,Ludwig H

更新日期：1994-05-15 00:00:00

abstract：BACKGROUND:In Western countries, esophageal squamous cell carcinoma is usually advanced at presentation and is rarely diagnosed in situ. The authors studied an in situ squamous cell carcinoma that occupied the entire mucosa of a 9 cm length of esophagus, causing dysphagia for solid food in a woman aged 68 years. METHO...

journal_title：Cancer

authors： Chu P,Stagias J,West AB,Traube M

更新日期：1997-05-15 00:00:00

abstract：BACKGROUND:Synovial sarcomas are high-grade soft tissue neoplasms often characterized by a biphasic spindle and epithelioid cell morphology. The majority of synovial sarcomas harbor a specific chromosomal translocation in which the proximal portion of the SYT gene at chromosome 18q11 is fused to the distal portion of o...

journal_title：Cancer

authors： Thomas DG,Giordano TJ,Sanders D,Biermann S,Sondak VK,Trent JC,Yu D,Pollock RE,Baker L

更新日期：2005-02-15 00:00:00

abstract：:Between March 1973, and December 1976, 22 patients who developed disease progression during or after MOPP therapy were treated with a new combination, B-CAVe (Bleomycin 5 mg/m2 iv days 1, 28, 35; CCNU 100 mg/m2 po day 1; adriamycin 60 mg/m2 iv day 1; and vinblastine 5 mg/m2 iv day 1). Objective responses were achieved...

journal_title：Cancer

authors： Porzig KJ,Portlock CS,Robertson A,Rosenberg SA

更新日期：1978-05-01 00:00:00

abstract：BACKGROUND:This paper gives an outline of the Casley-Smith method for the treatment of lymphedema of the arm. It includes a brief summary of the development of manual techniques and the terminology applied to them. METHODS:The four principles of this method are skin care, manual lymphatic drainage, compression in the ...

journal_title：Cancer

authors： Casley-Smith JR,Boris M,Weindorf S,Lasinski B

更新日期：1998-12-15 00:00:00

abstract：:This is a report of a gastric perforation secondary to a metastasis from a primary squamous cell carcinoma of the lung in a 70-year-old white man who was being treated with cimetidine for a presumed benign gastric ulcer. The literature concerning bronchogenic carcinoma metastasizing to the stomach and small bowel is r...

journal_title：Cancer

authors： Fletcher MS

更新日期：1980-10-15 00:00:00

abstract：BACKGROUND:Patients with aggressive non-Hodgkin lymphoma (NHL) require intensive and extensive therapy, which seems impracticable in elderly patients due to hematologic and extrahematologic toxicity. Consequent dose reduction and therapy attenuation can reduce treatment-related toxicity but also decreases therapeutic e...

journal_title：Cancer

authors： Rigacci L,Carpaneto A,Alterini R,Carrai V,Bernardi F,Bellesi G,Longo G,Bosi A,Rossi Ferrini P

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:The authors previously identified sperm protein 17 (Sp17) as being expressed in patients with multiple myeloma. The restricted expression of Sp17 in normal tissue makes it an ideal target for tumor vaccine. In the current study, the authors extended their research to include ovarian carcinoma. METHODS:A pai...

journal_title：Cancer

authors： Chiriva-Internati M,Wang Z,Salati E,Timmins P,Lim SH

更新日期：2002-05-01 00:00:00

abstract：BACKGROUND:Several studies have shown that Ashkenazi Jews in the United States and Israel have a high prevalence of the founder mutations BRCA1 185delAG, BRCA1 5382insC, BRCA2 6174delT, and APC I1307K at frequencies of 1.0--1.1%, 0.2--0.3%, 0.6--1.4%, and 6.1--7.0%, respectively. The objective of this study was to comp...

journal_title：Cancer

authors： Bahar AY,Taylor PJ,Andrews L,Proos A,Burnett L,Tucker K,Friedlander M,Buckley MF

更新日期：2001-07-15 00:00:00

abstract：:Jaundice and hepatomegaly developed in a boy with Fanconi anemia after he had undergone treatment with oxymetholone for nine years. A liver scan showed patchy uptake consistent with the presence of space-occupying lesions. After oxymetholone treatment was stopped, the jaundice resolved, the liver size decreased, and t...

journal_title：Cancer

authors： Obeid DA,Hill FG,Harnden D,Mann JR,Wood BS

更新日期：1980-09-15 00:00:00