Survival impact of surgical resection of primary tumor in patients with stage IV colorectal cancer: results from a large population-based cohort study.

abstract：BACKGROUND:The diagnosis of low-grade squamous intraepithelial lesion (LSIL), cannot exclude high-grade squamous intraepithelial lesion (LSIL-H) was not included in the 2001 Bethesda System. It is used in some institutions to diagnose cases that fulfill criteria for both the diagnosis of LSIL and atypical squamous cell...

journal_title：Cancer

authors： Alsharif M,Kjeldahl K,Curran C,Miller S,Gulbahce HE,Pambuccian SE

更新日期：2009-04-25 00:00:00

abstract：BACKGROUND:Forty patients with Stage II-III breast cancer with 10 or more positive axillary nodes were treated with mastectomy followed by four cycles of standard dose CAF (cytoxan, Adriamycin, 5-FU), followed by high dose cytoxan, cisplatin, carmustine (HDCT) with autologous bone marrow transplant support (ABMT), and ...

journal_title：Cancer

authors： Marks LB,Rosner GL,Prosnitz LR,Ross M,Vredenburgh JJ,Peters WP

更新日期：1994-12-01 00:00:00

abstract：BACKGROUND:Gastrointestinal stromal tumors (GISTs) are a specific clinicopathologic entity characterized by activating mutations in the c-KIT gene. These mutations are associated with increased immunohistochemical staining for the c-KIT protein. Because many GISTs display a definitive response to the KIT inhibitor imat...

journal_title：Cancer

authors： Willmore-Payne C,Layfield LJ,Holden JA

更新日期：2005-06-25 00:00:00

abstract：:During 1982 and 1983, 4496 new cases were recorded in the French Registry of acute leukemia and myelodysplastic syndromes by the French Group of Hematologic Morphology. This cooperative group associated members of 37 university centers spread throughout France; these centers handle the overwhelming majority of acute l...

journal_title：Cancer

authors：

更新日期：1987-09-15 00:00:00

abstract：BACKGROUND:This randomized pilot trial investigated whether primary chemotherapy was feasible in terms of efficacy, survival, toxicity profile, and quality of life compared with whole-brain radiotherapy (WBRT) given first in chemotherapy-naive patients nonsmall cell lung cancer (NSCLC) with synchronous brain metastasis...

journal_title：Cancer

authors： Lee DH,Han JY,Kim HT,Yoon SJ,Pyo HR,Cho KH,Shin SH,Yoo H,Lee SH,Lee JS

更新日期：2008-07-01 00:00:00

abstract：:The incidence of long thoracic nerve palsy after radical mastectomy has been documented to be approximately 10%. No cases have been reported after the more recent treatment for breast cancer, lumpectomy with axillary dissection. This more recent surgical procedure is customarily followed by aggressive radiation therap...

journal_title：Cancer

authors： Pugliese GN,Green RF,Antonacci A

更新日期：1987-09-15 00:00:00

abstract：:To evaluate the role of chemotherapy in local control of primary breast cancer, the incidence of local failure was evaluated in 768 patients treated with surgery and adjuvant, combination chemotherapy that contained fluorouracil, doxorubicin, and cyclophosphamide (FAC) at our institute between 1974 and 1982. Of these ...

journal_title：Cancer

authors： Buzdar AU,McNeese MD,Hortobagyi GN,Smith TL,Kau S,Fraschini G,Hug V,Ellerbroek N,Holmes FA,Ames F

更新日期：1990-02-01 00:00:00

abstract：:K-ras gene mutation in colorectal tumors from patients with familial polyposis coli were investigated using oligonucleotide probes specific for a mutation at codon 12, 13, or 61 of the K-ras gene. The authors examined 22 colorectal carcinomas and 51 colorectal adenomas from 41 familial polyposis coli patients and obse...

journal_title：Cancer

authors： Sasaki M,Sugio K,Sasazuki T

更新日期：1990-06-01 00:00:00

abstract：:Arylsulfatase B activity has been determined in 24-hour urine samples from 243 patients with colorectal cancer. Elevated activity of the enzyme was obsereved in 172 out of 243 (71%) patients. Employing Dukes' modified classification of colorectal cancer, urine arylsulfatase B activity was elevated in Dukes' A lesions-...

journal_title：Cancer

authors： Morgan LR Jr,Samuels MS,Thomas W,Krementz ET,Meeker W

更新日期：1975-12-01 00:00:00

abstract：:Doxorubicin is an effective antineoplastic agent, but it frequently causes dose-related cardiotoxic effects. Because the atrial natriuretic peptide (ANP) level is elevated in children with heart defects, the authors measured the ANP levels in children to determine whether ANP might serve as a simple diagnostic indicat...

journal_title：Cancer

authors： Bauch M,Ester A,Kimura B,Victorica BE,Kedar A,Phillips MI

更新日期：1992-03-15 00:00:00

abstract：BACKGROUND:To the authors' knowledge, little is known to date regarding the prognostic relevance of measuring serum levels of vascular endothelial growth factor (VEGF), a potent stimulator of angiogenesis, in patients with colon carcinoma who undergo surgery. METHODS:Preoperative and postoperative VEGF serum levels we...

journal_title：Cancer

authors： De Vita F,Orditura M,Lieto E,Infusino S,Morgillo F,Martinelli E,Castellano P,Romano C,Ciardiello F,Catalano G,Pignatelli C,Galizia G

更新日期：2004-01-15 00:00:00

abstract：BACKGROUND:Cancer costs should be discussed by patients and providers, but information is not readily available. Results from recently published studies (in the last 5 years) on direct and indirect cancer costs may help guide these discussions. METHODS:The authors reviewed studies published between 2013 and 2017 that ...

journal_title：Cancer

authors： Pisu M,Henrikson NB,Banegas MP,Yabroff KR

更新日期：2018-11-01 00:00:00

abstract：:To examine the relationship between smoking and stage of colorectal cancer at diagnosis, data on 2788 current smokers and 6313 nonsmokers with known stage at diagnosis were obtained from the Massachusetts Cancer Registry. The stage at diagnosis was treated as a polytomous response variable in a logit-type, log-linear ...

journal_title：Cancer

authors： Longnecker MP,Clapp RW,Sheahan K

更新日期：1989-09-15 00:00:00

abstract：BACKGROUND:Tamoxifen has been used in the treatment of patients with metastatic malignant melanoma either as a single agent or, more commonly, in combination with other chemotherapeutic agents. The aim of the current study was to summarize the available clinical evidence on the role of the tamoxifen in different combin...

journal_title：Cancer

authors： Lens MB,Reiman T,Husain AF

更新日期：2003-10-01 00:00:00

abstract：:Two hundred-eighty patients were randomized to receive either BCNU, hydroxyurea and imidazole carboxamide (BHD), BHD plus levamisole, or high-dose DTIC plus actinomycin D. There was no difference in response rate in the three groups (24%, 25% and 22%). Females responded better than males and, as expected, those with a...

journal_title：Cancer

authors： Costanzi JJ,Fletcher WS,Balcerzak SP,Taylor S,Eyre HJ,O'Bryan RM,Al-Sarraf M,Frank J

更新日期：1984-02-15 00:00:00

abstract：:The records of 1,497 patients with histologically proven adenocarcinoma of the stomach were reviewed from Charity Hospital over the 25-year period, 1948 to 1973. The operability rate was 82% and the resectability rate was 48%. In this series gastric carcinoma predominated in males and Negroes. Necropsy studies indicat...

journal_title：Cancer

authors： Dupont JB Jr,Lee JR,Burton GR,Cohn I Jr

更新日期：1978-03-01 00:00:00

abstract：BACKGROUND:Neuropilins (NRPs) are characterized as coreceptors of vascular endothelial growth factor (VEGF). In the current study, the authors assessed the expression of NRPs, VEGF, and vascular endothelial growth factor receptors (VEGFRs), as well as VEGF-induced cell proliferation, in pancreatic carcinoma cell lines ...

journal_title：Cancer

authors： Li M,Yang H,Chai H,Fisher WE,Wang X,Brunicardi FC,Yao Q,Chen C

更新日期：2004-11-15 00:00:00

abstract：BACKGROUND:Adenoid cystic carcinoma (ACC) of the head and neck (ACCHN) is a rare tumor of minor salivary, parotid, and submandibular glands. The biologic behavior of the disease is poorly understood, and nonsurgical treatment strategies have yet to be standardized. The long-term prognosis continues to be guarded, with ...

journal_title：Cancer

authors： Ellington CL,Goodman M,Kono SA,Grist W,Wadsworth T,Chen AY,Owonikoko T,Ramalingam S,Shin DM,Khuri FR,Beitler JJ,Saba NF

更新日期：2012-09-15 00:00:00

abstract：:This study investigated whether an endoscopic surveillance program for patients with "benign" gastric ulcers and gastric cancer leads to early detection of neoplasms and improves survival. The clinical course of all patients diagnosed between 1977 and 1986 as having either gastric ulcers or gastric cancer was followed...

journal_title：Cancer

authors： Eckardt VF,Giessler W,Kanzler G,Bernhard G

更新日期：1992-01-15 00:00:00

abstract：BACKGROUND:The Akt/mammalian target of the rapamycin (mTOR) signaling pathway represents a promising target for cancer therapy. The phosphorylation status of Akt and of mTOR's phosphorylation target eukaryotic initiation factor 4E-binding protein 1 (4E-BP1) is often used to assess the activity of Akt and mTOR signaling...

journal_title：Cancer

authors： Akcakanat A,Sahin A,Shaye AN,Velasco MA,Meric-Bernstam F

更新日期：2008-06-01 00:00:00

abstract：:External-beam irradiation of prostatic cancer was introduced at Stanford in 1956. The program has sought to determine the following: whether prostatic carcinoma can be cured by external beam radiation therapy, with what frequency this can be accomplished, which patients are best suited for irradiation, and what techni...

journal_title：Cancer

authors： Bagshaw MA,Ray GR,Cox RS

更新日期：1987-08-01 00:00:00

abstract：:It is justifiable to assume that a spontaneous regression of cervical intraepithelial neoplasia is in progress when pathologic epithelium is replaced by normal epithelium. Very rare histologic pictures of this process are shown. Dysplastic squamous epithelium or intraepithelial carcinomas become detached from their ba...

journal_title：Cancer

authors： Bajardi F

更新日期：1984-08-15 00:00:00

abstract：:A case of squamous cell carcinoma of the tongue in a 26-year-old man developing nine years after renal transplantation is presented. This is the first such case to be reported. Within seven months, widespread tumor metastases resulted in death. Pathologic examination of the transplanted kidney demonstrated neither re-...

journal_title：Cancer

authors： Lee YW,Gisser SD

更新日期：1978-01-01 00:00:00

abstract：:The clinical, histological, and ultrastructural aspects of a cervical paraganglioma of the vagus nerve, in a 66-year-old white man, have been discussed in detail. Ultrastructurally, the tumor chief cells contained characteristic membrane-bound and dense-cored neurosecretory granules which ranged in size from 85 millim...

journal_title：Cancer

authors： Chaudhry AP,Haar JG,Koul A,Nickerson PA

更新日期：1979-05-01 00:00:00

abstract：:Streptococcal agent OK-432 was administered at maintenance levels with conventional inductive chemotherapeutic agents to stage III and IV lung cancer patients. Survival rates were longer in patients treated with OK-432 than in patients treated without OK-432. An enhancement of lymphocyte blastogenic activity and a del...

journal_title：Cancer

authors： Kimura I,Ohnoshi T,Yasuhara S,Sugiyama M,Urabe Y

更新日期：1976-05-01 00:00:00

abstract：BACKGROUND:It has been established that comparative genomic hybridization (CGH) on Papanicolaou-stained cervical smears can be used to identify chromosomal imbalances. METHODS:In this study, the authors identified normal and dysplastic squamous epithelial cells cytologically, eliminated surrounding bacteria or leukocy...

journal_title：Cancer

authors： Aubele M,Zitzelsberger H,Schenck U,Walch A,Höfler H,Werner M

更新日期：1998-12-25 00:00:00

abstract：:During the period from September, 1976 to June, 1979, 70 patients with locoregional or extensive epidermoid carcinoma of the esophagus were treated with the two-drug combination of cisplatin and bleomycin (DB). For the 43 patients with locoregional disease (LRD), DB was used prior to surgery and/or radiation therapy; ...

journal_title：Cancer

authors： Coonley CJ,Bains M,Hilaris B,Chapman R,Kelsen DP

更新日期：1984-12-01 00:00:00

abstract：:Oncologic therapy demands technologic sophistication to meet the clinical challenges of proper drug administration for chemotherapeutic agents, pain management, antibiotics, hydration, antiemetic drugs, and total parenteral nutrition. Drug administration systems for patient-controlled analgesia include benefits of imp...

journal_title：Cancer

authors： Shaw HL

更新日期：1992-08-15 00:00:00

abstract：BACKGROUND:The experience of one institution in treating soft tissue sarcomas of the head and neck in a pediatric population is presented. METHODS:Case materials of 134 patients younger than 20 years who were referred to the University of Texas M. D. Anderson Cancer Center between 1970 and 1989 for treatment of sarcom...

journal_title：Cancer

authors： Lyos AT,Goepfert H,Luna MA,Jaffe N,Malpica A

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND:It is challenging for clinicians to foster coping and allow hope when discussing prognosis and end-of-life (EOL) issues with terminally ill cancer patients and their caregivers. To the authors' knowledge, little research evidence is currently available to guide clinical practice. METHODS:The authors conduct...

journal_title：Cancer

authors： Clayton JM,Butow PN,Arnold RM,Tattersall MH

更新日期：2005-05-01 00:00:00