Immunochemotherapy in human lung cancer using the streptococcal agent OK-432.

abstract：BACKGROUND:The objective of this study was to characterize chronic disease, health-related quality of life (HRQOL), emotional distress, and social attainment among long-term survivors of neuroblastoma. METHODS:Chronic health conditions among 136 ≥10-year neuroblastoma survivors (median age, 31.9 years; range, 20.2-54....

journal_title：Cancer

authors： Wilson CL,Brinkman TM,Cook C,Huang S,Hyun G,Green DM,Furman WL,Bhakta N,Ehrhardt MJ,Krasin MJ,Robison LL,Ness KK,Hudson MM

更新日期：2020-03-15 00:00:00

abstract：BACKGROUND:The purpose of this article was to evaluate the utility of a pharmacokinetically modeled measure of regional contrast access, based on dynamic contrast-enhanced magnetic resonance imaging (MRI) studies after preoperative chemotherapy, as a predictor of disease free survival in osteosarcoma. METHODS:The kine...

journal_title：Cancer

authors： Reddick WE,Wang S,Xiong X,Glass JO,Wu S,Kaste SC,Pratt CB,Meyer WH,Fletcher BD

更新日期：2001-06-15 00:00:00

abstract：:The long-term cancer specific survival based on individual follow-up and analysis of prospectively collected data from 1061 patients undergoing resection for carcinoma of the rectum is presented. All patients were operated on and managed by one surgeon. Survival data for 978 cases were analyzed according to the method...

journal_title：Cancer

authors： Pihl E,Hughes ES,McDermott FT,Milne BJ,Korner JM,Price AB

更新日期：1980-06-01 00:00:00

abstract：:One hundred two long-term survivors of childhood cancers with second malignant neoplasms (SMNs) were collected from 10 institutions. Forty-seven cases fulfilling study criteria were studied to determine the risk of developing a SMN in irradiated fields after exposure to various chemotherapeutic agents. The case contro...

journal_title：Cancer

authors： D'Angio GJ,Meadows A,Miké V,Harris C,Evans A,Jaffe N,Newton W,Schweisguth O,Sutow W,Morris-Jones P

更新日期：1976-02-01 00:00:00

abstract：BACKGROUND:Clinical drug resistance is recognized in patients previously treated with radiotherapy and after chemotherapy. In vitro exposure of mammalian tumor cells to fractionated X-irradiation also resulted in the expression of drug resistance. Analysis of the resistance phenotype of irradiated Chinese hamster ovary...

journal_title：Cancer

authors： Hill BT,Whelan RD,Hurst HC,McClean S

更新日期：1994-06-15 00:00:00

abstract：BACKGROUND:As androgen deprivation therapy (ADT) becomes a standard of treatment for men with recurrent or metastatic prostate cancer, evaluation of adverse effects associated with this treatment is needed. In this study, the authors evaluated the effect of ADT administered as monotherapy and in combination with local ...

journal_title：Cancer

authors： Sadetsky N,Greene K,Cooperberg MR,Hubbard A,Carroll PR,Satariano W

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND:The authors recently reported on the role of cyclin E in differentiating ovarian/primary peritoneal carcinoma from malignant peritoneal mesothelioma using gene expression arrays. In the current study, they analyzed the expression of low-molecular weight (LMW) forms of cyclin E in ovarian carcinoma, malignant...

journal_title：Cancer

authors： Davidson B,Skrede M,Silins I,Shih IeM,Trope CG,Flørenes VA

更新日期：2007-09-15 00:00:00

abstract：BACKGROUND:Chronic myeloid leukemia (CML) may progress to blast phase (BP) at the rate of 1% to 1.5% per year. With the use of single-agent tyrosine kinase inhibitors, median overall survival ranges between 7 and 11 months. METHODS:The outcome was analyzed for 42 patients with lymphoid BP-CML who were treated with hyp...

journal_title：Cancer

authors： Strati P,Kantarjian H,Thomas D,O'Brien S,Konoplev S,Jorgensen JL,Luthra R,Abruzzo L,Jabbour E,Quintas-Cardama A,Borthakur G,Faderl S,Ravandi F,Cortes J

更新日期：2014-02-01 00:00:00

abstract：:Activities of glucosephosphate isomerase, lactate dehydrogenase, and NADP-isocitrate dehydrogenase were significantly elevated in breast cancer specimens from patients who responded favorably to combination cytotoxic chemotherapy regimens compared with those in carcinomas from patients failing to respond to the same c...

journal_title：Cancer

authors： Hilf R,Savlov ED,Rector WD,Wittliff JL

更新日期：1976-08-01 00:00:00

abstract：BACKGROUND:There is an increasing number of articles regarding the long term follow-up of Papanicolaou (Pap) smears with the diagnosis of atypical squamous cells of undetermined significance (ASCUS). Much controversy exists regarding the management of patients with this diagnosis. In a prior study in 1992, the authors ...

journal_title：Cancer

authors： Stastny JF,Remmers RE,London WB,Pedigo MA,Cahill LA,Ryan M,Frable WJ

更新日期：1997-12-25 00:00:00

abstract：:Eighty-six children with non-Hodgkin's lymphoma were studied from 1964 to January 31, 1975. Seventy-six percent of the 43 patients in the nonprotocol group had far advanced disease, and 76% had Rappaport's diffuse histology. Only 11% of these patients survived free of disease. The second group of 43 patients received ...

journal_title：Cancer

authors： Wollner N,Burchenal JH,Lieberman PH,Exelby P,D'Angio G,Murphy ML

更新日期：1976-01-01 00:00:00

abstract：:The effects of radiotherapy on immune status in patients with localized carcinoma of the cervix have been assessed serially up to 5 years remission by a wide range of methods. Neutrophil function and serum immunoglobulins were essentially normal throughout. Peripheral blood neutrophil and lymphocyte counts and the pro...

journal_title：Cancer

authors： Hancock BW,Bruce L,Whitham MD,Ward AM

更新日期：1984-02-15 00:00:00

abstract：:Five cases of primary intestinal lymphoma are described. The main clinical features included abdominal pain, diarrhea, and marked weight loss, together with radiologic and some laboratory findings suggestive of malabsorption. Laparatomy perfomed in four cases revealed dilatation of the small intestine, with mesenteric...

journal_title：Cancer

authors： Shahid MJ,Alami SY,Nassar VH,Balikian JB,Salem AA

更新日期：1975-03-01 00:00:00

abstract：BACKGROUND:There is no clear consensus between pediatric and adult providers about the treatment of adolescents and young adults (AYAs) with Hodgkin lymphoma (HL). METHODS:Failure-free survival (FFS) and overall survival (OS) were compared between 114 patients ages 17 to 21 years with HL who were treated on the Easter...

journal_title：Cancer

authors： Henderson TO,Parsons SK,Wroblewski KE,Chen L,Hong F,Smith SM,McNeer JL,Advani RH,Gascoyne RD,Constine LS,Horning S,Bartlett NL,Shah B,Connors JM,Leonard JI,Kahl BS,Kelly KM,Schwartz CL,Li H,Friedberg JW,Friedman D

更新日期：2018-01-01 00:00:00

abstract：:The histologic findings of five patients with clinically typical Bowenoid dysplasia (BD) allowed the authors to classify the vulvar and perineal biopsies of 18 patients under 40 years as BD and the vulvar biopsies of six patients under 40 years as squamous cell carcinoma in situ (CIS). The two best criteria for BD are...

journal_title：Cancer

authors： Ulbright TM,Stehman FB,Roth LM,Ehrlich CE,Ransburg RC

更新日期：1982-12-15 00:00:00

abstract：:While investigating the cause of mild polycythemia in a young man, a testicular seminoma was discovered with unusual and tumor-dependent features: an absolute polycythemia with high plasma erythropoietin (EPO) levels, an overproduction of estradiol and testosterone, and a dramatic Leydig cell hyperplasia surrounding t...

journal_title：Cancer

authors： Reman O,Reznik Y,Casadevall N,Lacombe C,Troussard X,Mandard JC,Leporrier M,Mahoudeau J

更新日期：1991-11-15 00:00:00

abstract：:Flow cytometry studies of the DNA distribution of tumor cells from 92 human breast cancers showed measurable aneuploidy (hyperploidy) in 83 cases (92%). The DNA ploidy values were unimodal in each case, but there was a bimodal distribution for the entire series. One group of tumors had a diploid or near diploid DNA di...

journal_title：Cancer

authors： Olszewski W,Darzynkiewicz Z,Rosen PP,Schwartz MK,Melamed MR

更新日期：1981-08-15 00:00:00

abstract：BACKGROUND:Early stage lung cancer has a variable prognosis, and there are currently no markers that predict which patients will recur. This study examined the relation between tumor-regulatory T (Treg) cells and total tumor-infiltrating T-cell lymphocytes (TIL) to determine whether they correlated with recurrence. ME...

journal_title：Cancer

authors： Petersen RP,Campa MJ,Sperlazza J,Conlon D,Joshi MB,Harpole DH Jr,Patz EF Jr

更新日期：2006-12-15 00:00:00

abstract：:Actuarial progression-free survival rate at 5 years of a series of 34 patients with medulloblastoma treated by combined surgery, radiotherapy, and chemotherapy was 71%. No relapses were observed in 14 patients followed for more than 5 years. Treatment consisted of a short postoperative course of vincristine (VCR) and ...

journal_title：Cancer

authors： Bellani FF,Gasparini M,Lombardi F,Zucali R,Luccarelli G,Migliavacca F,Moise S,Nicola G

更新日期：1984-11-01 00:00:00

abstract：BACKGROUND:Breast conservation is now established treatment for patients with small breast cancers. The authors reviewed a large series of patients with long term follow-up who underwent conservative treatment. Clinical and pathologic factors were analyzed to identify patients at an increased risk of relapse in the bre...

journal_title：Cancer

authors： Dewar JA,Arriagada R,Benhamou S,Benhamou E,Bretel JJ,Pellae-Cosset B,Marin JL,Petit JY,Contesso G,Sarrazin D

更新日期：1995-12-01 00:00:00

abstract：BACKGROUND:Survival trends provide a measure of improvement in detection and treatment over time. In the current study, updated childhood and adolescent cancer survival statistics are presented, overall and among demographic subgroups, including Hispanics, for whom to the authors' knowledge national rates have not been...

journal_title：Cancer

authors： Linabery AM,Ross JA

更新日期：2008-11-01 00:00:00

abstract：:Among 164 patients with acute lymphoblastic leukemia (ALL) (age greater than 11 years) induced into complete remission at four hospitals in Italy and The Netherlands between 1971-1977, 49 survived for more than three years in continuous complete remission. Features at diagnosis of the 49 long-term survivors were compa...

journal_title：Cancer

authors： Amadori S,Meloni G,Baccarani M,Haanen C,Willemze R,Corbelli G,Drenthe-Schonk A,Cardozo PL,Tura S,Mandelli F

更新日期：1983-07-01 00:00:00

abstract：BACKGROUND:This survey documents the strategies used by pain control physicians in the selection of opioid drugs and routes of administration in the management of inpatients referred to a cancer pain service. METHODS:The following approaches were prospectively evaluated during the treatment of 100 consecutive inpatien...

journal_title：Cancer

authors： Cherny NJ,Chang V,Frager G,Ingham JM,Tiseo PJ,Popp B,Portenoy RK,Foley KM

更新日期：1995-10-01 00:00:00

abstract：BACKGROUND:Extragonadal germ cell tumors (EGGCT) are uncommon, occur primarily in the mediastinum and retroperitoneum, and have been noted to have variable response rates to cisplatin-based chemotherapy regimens. METHODS:The Southwest Oncology Group (SWOG) has completed a prospective trial of combination chemotherapy ...

journal_title：Cancer

authors： Bukowski RM,Wolf M,Kulander BG,Montie J,Crawford ED,Blumenstein B

更新日期：1993-04-15 00:00:00

abstract：BACKGROUND:Historically, estrogen receptor (ER) determinations have been made by the ligand-binding assay of tumor homogenates, primarily by the dextran-coated charcoal method (DCC). Immunocytochemical assays (ICA) for ER are more recent and have been executed mostly on frozen sections with the monoclonal antibody H222...

journal_title：Cancer

authors： Pertschuk LP,Feldman JG,Kim YD,Braithwaite L,Schneider F,Braverman AS,Axiotis C

更新日期：1996-06-15 00:00:00

abstract：:Forty-four patients with advanced carcinoma of the head and neck were treated with cyclophosphamide, 400 mg/m2 plus BCNU, 100 mg/m2 day 1 followed by adriamycin 40 mg/m2 day 2, with therapy repeated every 4 weeks. Of 31 evaluable patients, there were 1 complete response, and 10 partial responses (35%). Four of 8 patie...

journal_title：Cancer

authors： Presant CA,Ratkin G,Klahr C,Brown C

更新日期：1979-11-01 00:00:00

abstract：:The ability to noninvasively discriminate the most common types of renal cell carcinoma (RCC) based on their magnetic resonance imaging (MRI) appearances or their magnetic resonance phenotypes is achievable. Intracellular lipids, a histologic characteristic of the clear cell RCC, can be identified on chemical shift MR...

journal_title：Cancer

authors： Pedrosa I,Alsop DC,Rofsky NM

更新日期：2009-05-15 00:00:00

abstract：BACKGROUND:Physical activity has been related to improved breast cancer outcomes. Especially in the older breast cancer population, physical activity may be important because old age is associated with comorbidities and decreased physical function. The purpose of this study was to investigate the relation between physi...

journal_title：Cancer

authors： de Glas NA,Fontein DB,Bastiaannet E,Pijpe A,De Craen AJ,Liefers GJ,Nortier HJ,de Haes HJ,van de Velde CJ,van Leeuwen FE

更新日期：2014-09-15 00:00:00

abstract：:Review of 61 surgically resected small hepatocellular carcinomas (HCC) less than or equal to 3 cm in diameter yielded a simple gross classification system of five types based on tumor shape, which is highly correlated with microscopic and clinical features, including prognosis. Type 1 (single nodular type) tumors (n =...

journal_title：Cancer

authors： Kanai T,Hirohashi S,Upton MP,Noguchi M,Kishi K,Makuuchi M,Yamasaki S,Hasegawa H,Takayasu K,Moriyama N

更新日期：1987-08-15 00:00:00

abstract：:The disposition of many drugs in obesity is altered, although little is known of the effect of obesity on the pharmacokinetics of anti-cancer drugs. In this report the authors describe the pharmacokinetics of high-dose methotrexate in an obese woman (184% ideal body weight) with osteosarcoma. For this patient, both th...

journal_title：Cancer

authors： Fleming RA,Eldridge RM,Johnson CE,Stewart CF

更新日期：1991-09-15 00:00:00