Primary intestinal lymphoma with paraproteinemia.

Abstract:

:Five cases of primary intestinal lymphoma are described. The main clinical features included abdominal pain, diarrhea, and marked weight loss, together with radiologic and some laboratory findings suggestive of malabsorption. Laparatomy perfomed in four cases revealed dilatation of the small intestine, with mesenteric node enlargement. In these four instances there was a definite histologic evidence of malignant lymphoma, either initially or later in the course of the disease. A characteristic feature here was the diffuse infiltration of the intestinal mucosa with plasma cells, which in the deeper layers became progressively atypical and were mixed with histiocytes and giant cells. A similar infiltrate was seen in the mesenteric nodes. Immunoelectrophoresis showed the pattern of IgA heavy chain disease. It is suggested that the latter is a variant of primary intestinal lymphoma and not a separate disease entity.

journal_name

Cancer

journal_title

Cancer

authors

Shahid MJ,Alami SY,Nassar VH,Balikian JB,Salem AA

doi

10.1002/1097-0142(197503)35:3<848::aid-cncr2820350

subject

Has Abstract

pub_date

1975-03-01 00:00:00

pages

848-58

issue

3

eissn

0008-543X

issn

1097-0142

journal_volume

35

pub_type

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