Radiotherapy or surgery for head and neck squamous cell cancer: establishing the baseline for hypopharyngeal carcinoma?

abstract：BACKGROUND:The goal of the current study was to investigate the prognostic impact of proliferative activity, together with the other classic clinicopathologic prognostic factors (tumor size, tumor grade, receptor status, ploidy, and lymph node status), in breast carcinoma by counting mitoses and evaluating S phase frac...

journal_title：Cancer

authors： Michels JJ,Marnay J,Delozier T,Denoux Y,Chasle J

更新日期：2004-02-01 00:00:00

abstract：:Four patients with benign giant cell tumor and one patient with probable benign giant cell tumor associated with Paget's disease of bone are reported. The familial and geographic clustering of these cases is unique in that three patients were related and all patients traced ancestral roots to the same area of southern...

journal_title：Cancer

authors： Jacobs TP,Michelsen J,Polay JS,D'Adamo AC,Canfield RE

更新日期：1979-08-01 00:00:00

abstract：BACKGROUND:Histologic response to chemotherapy has been shown to be an independent prognostic factor in patients with osteosarcoma and Ewing sarcoma. However, in patients with soft tissue sarcoma (STS), the prognostic impact of histologic response to chemotherapy is less clear. In the current study, the authors sought ...

journal_title：Cancer

authors： Mullen JT,Hornicek FJ,Harmon DC,Raskin KA,Chen YL,Szymonifka J,Yeap BY,Choy E,DeLaney TF,Nielsen GP

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND:Although cutaneous desmoplastic malignant melanoma (DMM) has been well characterized, those arising from the oral mucosa have been less well defined. METHODS:We evaluated the clinical and pathologic features of three patients with biopsy-proven DMM examined at the North Carolina Baptist Hospital. Routine he...

journal_title：Cancer

authors： Kilpatrick SE,White WL,Browne JD

更新日期：1996-08-01 00:00:00

abstract：BACKGROUND:Splenic and nodal marginal zone lymphomas (MZL) are subtypes of marginal zone-derived neoplasms. Due to their rarity, little is known concerning their relation, pattern of dissemination, and treatment outcome. METHODS:The authors analyzed the clinicopathologic features and outcome of 43 patients (34 patient...

journal_title：Cancer

authors： Arcaini L,Paulli M,Boveri E,Vallisa D,Bernuzzi P,Orlandi E,Incardona P,Brusamolino E,Passamonti F,Burcheri S,Schena C,Pascutto C,Cavanna L,Magrini U,Lazzarino M

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:Attrition is common among supportive care/palliative oncology clinical trials. However, to the authors' knowledge, few studies to date have documented the reasons and predictors for dropout. In the current study, the authors' objective was to determine the rate, reasons, and factors associated with attrition...

journal_title：Cancer

authors： Hui D,Glitza I,Chisholm G,Yennu S,Bruera E

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND:Previous studies have shown that low levels of p27(Kip1), an inhibitor of G1 cyclin-dependent kinases, are associated with high aggressiveness and poor prognosis in a variety of cancers. Decreased levels of p27 are caused, at least in part, by acceleration of the rate of its ubiquitin-mediated degradation. I...

journal_title：Cancer

authors： Hershko D,Bornstein G,Ben-Izhak O,Carrano A,Pagano M,Krausz MM,Hershko A

更新日期：2001-05-01 00:00:00

abstract：BACKGROUND:This study sought to evaluate patient-reported health-related quality of life following proton therapy for prostate cancer in men ≤ 60 years old. METHODS:Between August 2006 and January 2010, 262 hormone-naive men ≤ 60 years old were treated with definitive proton therapy for prostate cancer. Before treatme...

journal_title：Cancer

authors： Hoppe BS,Nichols RC,Henderson RH,Morris CG,Williams CR,Costa J,Marcus RB Jr,Mendenhall WM,Li Z,Mendenhall NP

更新日期：2012-09-15 00:00:00

abstract：:Ninety-five malignant tumors in the submandibular gland, the sublingual gland, and the minor salivary glands seen in a 25-year period were reviewed. The patients were retrospectively staged using the Union Internationale Contre le Cancer (UICC) classification. The most frequent tumor was adenoid cystic carcinoma, foll...

journal_title：Cancer

authors： Andersen LJ,Therkildsen MH,Ockelmann HH,Bentzen JD,Schiødt T,Hansen HS

更新日期：1991-12-01 00:00:00

abstract：:Four cell lines were derived from childhood malignancies: rhabdomyosarcoma, sarcoma, lymphosarcoma and an American Burkitt's lymphoma. Cells of the four lines formed tumors in immunosuppressed newborn hamsters. The tumors had a microscopic appearance like that of the tumors from which the cell lines were derived. No ...

journal_title：Cancer

authors： McAllister RM,Nelson-Rees WA,Peer M,Laug WE,Isaacs H Jr,Gilden RV,Rongey RW,Gardner MB

更新日期：1975-11-01 00:00:00

abstract：:The prolonged administration of bisphosphonates can reduce the frequency of morbid skeletal events in patients with metastatic breast carcinoma or multiple myeloma. The development of more potent bisphosphonates will simplify current therapeutic schemes and could improve the therapeutic effectiveness of bisphosphonate...

journal_title：Cancer

authors： Body JJ

更新日期：1997-10-15 00:00:00

abstract：BACKGROUND:Serum alpha-L-fucosidase activity is considered a marker of hepatocellular carcinoma. To the authors' knowledge, its clinical usefulness in the early detection of hepatocellular carcinoma in the follow-up of cirrhotic patients has not been reported previously. METHODS:The authors prospectively studied serum...

journal_title：Cancer

authors： Giardina MG,Matarazzo M,Morante R,Lucariello A,Varriale A,Guardasole V,De Marco G

更新日期：1998-12-15 00:00:00

abstract：BACKGROUND:Response rates in chronic myeloid leukemia (CML) are now reported based on the cumulative incidence of a single-time best response. The study aim was to examine the significance of different response criteria for CML on imatinib therapy. METHODS:In all, 276 patients with chronic phase CML on imatinib therap...

journal_title：Cancer

authors： Kantarjian H,O'Brien S,Shan J,Huang X,Garcia-Manero G,Faderl S,Ravandi-Kashani F,Verstovsek S,Beth Rios M,Cortes J

更新日期：2008-02-15 00:00:00

abstract：BACKGROUND:A previous comparative tissue proteomics study by the authors of the current study led to the identification of caldesmon (CaD) as one of the proteins associated with cervical metastasis of oral cavity squamous cell carcinoma (OSCC). In the current investigation, the authors focused on the potential function...

journal_title：Cancer

authors： Chang KP,Wang CL,Kao HK,Liang Y,Liu SC,Huang LL,Hseuh C,Hsieh YJ,Chien KY,Chang YS,Yu JS,Chi LM

更新日期：2013-11-15 00:00:00

abstract：BACKGROUND:Although ascites cytology is important for therapeutic strategies, it is difficult to distinguish cancer infiltration from reactive mesothelial proliferation in some patients. In this study, the authors applied CDX2 immunocytochemistry to improve diagnostic accuracy. METHODS:The authors examined the distrib...

journal_title：Cancer

authors： Kobayashi M,Ueyama Y,Nakanishi H,Ishida H,Takahashi E,Nakamura S,Koshikawa T,Yatabe Y

更新日期：2006-04-25 00:00:00

abstract：:An in vivo model is described for assessing the antitumor activity of chemotherapeutic agents. Tumors derived from human colon carcinoma cell lines injected into antithymocyte serum (ATS) immunosuppressed mice were used. In this system, both antitumor effects and host toxicity can be quantitated, permitting calculatio...

journal_title：Cancer

authors： Tibbetts LM,Chu MY,Hager JC,Dexter DL,Calabresi P

更新日期：1977-11-01 00:00:00

abstract：BACKGROUND:Treatment of febrile neutropenia (FN) is costly, because it typically involves hospitalization. As cancer rates continue to increase, the number of patients suffering from FN will also increase, making it important to quantify the costs of treating this condition accurately and comprehensively. METHODS:A co...

journal_title：Cancer

authors： Lathia N,Mittmann N,DeAngelis C,Knowles S,Cheung M,Piliotis E,Shear N,Walker S

更新日期：2010-02-01 00:00:00

abstract：BACKGROUND:BRAF inhibitors are effective in melanoma and other cancers with BRAF mutations; however, patients ultimately develop therapeutic resistance through the activation of alternative signaling pathways such as RAF/RAS or MET. The authors hypothesized that combining the BRAF inhibitor vemurafenib with either the ...

journal_title：Cancer

authors： Janku F,Sakamuri D,Kato S,Huang HJ,Call SG,Naing A,Holley VR,Patel SP,Amaria RN,Falchook GS,Piha-Paul SA,Zinner RG,Tsimberidou AM,Hong DS,Meric-Bernstam F

更新日期：2021-02-01 00:00:00

abstract：:Bone scanning is a sensitive test for the detection of metastatic breast cancer, but not all abnormal findings on bone scan are diagnostic of skeletal metastasis. Recent studies have found a relatively low rate (less than or equal to 5%) of abnormal scans in patients with Stage I and II breast cancers, and only half o...

journal_title：Cancer

authors： Lee YT

更新日期：1981-02-01 00:00:00

abstract：BACKGROUND:Despite known benefits to needle biopsy for suspicious breast lesions, variability in the use of this technique has been documented in practice. We sought to study the use of needle biopsy and open surgical biopsy in women with breast cancer, predictors of needle biopsy use, and the effect of biopsy choice o...

journal_title：Cancer

authors： Friese CR,Neville BA,Edge SB,Hassett MJ,Earle CC

更新日期：2009-02-15 00:00:00

abstract：BACKGROUND:The effect on prognosis of adding imatinib mesylate to the treatment of patients with Philadelphia chromosome (Ph)-positive chronic myelogenous leukemia (CML) has not been explored fully. The objective of the current study was to evaluate the benefit of adding imatinib to the treatment sequence of patients w...

journal_title：Cancer

authors： Kantarjian H,O'Brien S,Cortes J,Shan J,Giles F,Garcia-Manero G,Verstovsek S,Faderl S,Rios MB,Talpaz M

更新日期：2003-10-01 00:00:00

abstract：BACKGROUND:Tamoxifen is a prototypic cancer chemopreventive agent, yet clinical trials have not evaluated its effect on mortality or the impact of drug pricing on its cost-effectiveness. METHODS:A state-transition Markov model for a hypothetical cohort of women age 50 years was used to evaluate the effects of tamoxife...

journal_title：Cancer

authors： Melnikow J,Kuenneth C,Helms LJ,Barnato A,Kuppermann M,Birch S,Nuovo J

更新日期：2006-09-01 00:00:00

abstract：:A case of a dermal nerve sheath myxoma arising in a digital nerve is reported. Similar tumors and its variants have been termed neurothekeoma, pacinian neurofibroma, bizarre cutaneous neurofibroma, and plexiform neurofibroma. The perineural sheath or the Schwann cell have been presumed to be the cell of origin by seve...

journal_title：Cancer

authors： Blumberg AK,Kay S,Adelaar RS

更新日期：1989-03-15 00:00:00

abstract：BACKGROUND:This study was performed to develop a sensitive method for the detection of circulating hepatocellular carcinoma (HCC) cells in peripheral blood, in advance of the diagnosis of distant metastasis of HCC by conventional means. METHODS:Peripheral blood (5 ml) samples were obtained from 64 patients with HCC an...

journal_title：Cancer

authors： Komeda T,Fukuda Y,Sando T,Kita R,Furukawa M,Nishida N,Amenomori M,Nakao K

更新日期：1995-05-01 00:00:00

abstract：BACKGROUND:This study explores whether externalizing religious and spiritual beliefs is associated with advanced-stage colon cancer at initial oncology presentation and whether this association is stronger for blacks than for whites. METHODS:Patients who had newly diagnosed, invasive colon cancer were recruited at 9 s...

journal_title：Cancer

authors： Polite BN,Cipriano-Steffens TM,Hlubocky FJ,Jean-Pierre P,Cheng Y,Brewer KC,Rauscher GH,Fitchett GA

更新日期：2018-06-15 00:00:00

abstract：:Among 164 patients with acute lymphoblastic leukemia (ALL) (age greater than 11 years) induced into complete remission at four hospitals in Italy and The Netherlands between 1971-1977, 49 survived for more than three years in continuous complete remission. Features at diagnosis of the 49 long-term survivors were compa...

journal_title：Cancer

authors： Amadori S,Meloni G,Baccarani M,Haanen C,Willemze R,Corbelli G,Drenthe-Schonk A,Cardozo PL,Tura S,Mandelli F

更新日期：1983-07-01 00:00:00

abstract：:Twenty-nine patients treated with adjuvant chemotherapy for carcinoma of the breast were evaluated for frequency and amount of weight gained during treatment. No difference with respect to age, menopausal status, estrogen receptor status, nodal status, biochemical parameters, or treatment regimen (CMF versus CMFVP) we...

journal_title：Cancer

authors： Huntington MO

更新日期：1985-08-01 00:00:00

abstract：BACKGROUND:Although almost half of all incidents of breast carcinoma occur in women age > or = 65 years, not enough is known about appropriate care for patients in this age group. The objective of the current study was to evaluate the role of breast conservation therapy in the management of breast carcinoma in women ag...

journal_title：Cancer

authors： Vlastos G,Mirza NQ,Meric F,Hunt KK,Kuerer HM,Ames FC,Ross MI,Buchholz TA,Hortobagyi GN,Singletary SE

更新日期：2001-09-01 00:00:00

abstract：BACKGROUND:Male patients with oral and oropharyngeal cancer are known to have high risk of concomitant esophageal cancer developing. Thus, mass screening programs are pursued to detect such esophageal cancer early, and in a mass screening trial of patients with early oral and oropharyngeal cancer, the efficacy of Lugol...

journal_title：Cancer

authors： Ina H,Shibuya H,Ohashi I,Kitagawa M

更新日期：1994-04-15 00:00:00

abstract：:Twenty-two children with acute lymphocytic leukemia (ALL) who had relapsed while on therapy and for whom remissions were successfully reinduced were maintained with a combination of methotrexate, daunomycin, 6-mercaptopurine, prednisone, and vincristine (Djerassi-methotrexate with BOMB). The median duration of remissi...

journal_title：Cancer

authors： Kimball JC,Herson J,Sullivan MP

更新日期：1980-09-01 00:00:00